DK270983D0 - 1-aryloxy-2,3,4,5-tetrahydro-3--benzazepiner, en fremgangsmade til fremstilling deraf og deres anvendelse - Google Patents

1-aryloxy-2,3,4,5-tetrahydro-3--benzazepiner, en fremgangsmade til fremstilling deraf og deres anvendelse

Info

Publication number
DK270983D0
DK270983D0 DK2709/83A DK270983A DK270983D0 DK 270983 D0 DK270983 D0 DK 270983D0 DK 2709/83 A DK2709/83 A DK 2709/83A DK 270983 A DK270983 A DK 270983A DK 270983 D0 DK270983 D0 DK 270983D0
Authority
DK
Denmark
Prior art keywords
sub
hydrogen
lower alkyl
benzazepines
tetrahydro
Prior art date
Application number
DK2709/83A
Other languages
English (en)
Other versions
DK270983A (da
Inventor
Richard Charles Effland
Joseph Thomas Klein
Larry Davis
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK270983D0 publication Critical patent/DK270983D0/da
Publication of DK270983A publication Critical patent/DK270983A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK270983A 1982-06-14 1983-06-13 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse DK270983A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/387,916 US4988690A (en) 1982-06-14 1982-06-14 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof

Publications (2)

Publication Number Publication Date
DK270983D0 true DK270983D0 (da) 1983-06-13
DK270983A DK270983A (da) 1983-12-15

Family

ID=23531838

Family Applications (1)

Application Number Title Priority Date Filing Date
DK270983A DK270983A (da) 1982-06-14 1983-06-13 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepiner, en fremgangsmaade til fremstilling deraf og deres anvendelse

Country Status (17)

Country Link
US (1) US4988690A (da)
EP (1) EP0096838B1 (da)
JP (1) JPS595165A (da)
KR (1) KR900001214B1 (da)
AT (1) ATE26263T1 (da)
AU (1) AU570920B2 (da)
CA (1) CA1214460A (da)
DE (1) DE3370621D1 (da)
DK (1) DK270983A (da)
ES (1) ES523191A0 (da)
FI (1) FI78473C (da)
GR (1) GR78291B (da)
HU (1) HU190902B (da)
IE (1) IE55404B1 (da)
IL (1) IL68964A (da)
PT (1) PT76864B (da)
ZA (1) ZA834309B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA882080B (en) * 1987-03-27 1989-04-26 Schering Corp Substituted benzazepines,their preparation and pharmaceutical compositions containing them
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ZA885824B (en) * 1987-08-14 1989-04-26 Merrell Dow Pharma Novel antidepressants
US5202319A (en) * 1991-09-23 1993-04-13 Hoechst-Roussel Pharmaceuticals Inc. Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5639482A (en) * 1993-11-10 1997-06-17 Crary; Ely J. Composition for control and prevention of diabetic retinopathy
WO2002044144A2 (en) * 2000-11-30 2002-06-06 Advanced Research And Technology Institute, Inc. Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CN101792417A (zh) * 2003-06-17 2010-08-04 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
MXPA05013364A (es) 2003-06-17 2006-03-17 Arena Pharm Inc Procedimiento para preparar 3-benzazepinas.
WO2005042491A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
SI1838677T1 (sl) 2004-12-21 2010-01-29 Arena Pharm Inc Kristalne oblike (R)-8-kloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzazepin hidroklorida
EA015012B1 (ru) 2004-12-23 2011-04-29 Арена Фармасьютикалз, Инк. Композиция, содержащая фентермин и избирательный агонист рецептора 5ht, и ее применение
SG10201508066VA (en) 2006-04-03 2015-10-29 Arena Pharm Inc Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
ES2522587T3 (es) * 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma
EP2146720A4 (en) 2007-05-10 2012-01-18 Amr Technology Inc ARYLOXY- AND HETEROARYLOXY-SUBSTITUTED TETRAHYDROBENZAZEPINE AND THEIR USE FOR THE RECOURSE-INHIBITION OF NOREPINEPHRIN, DOPAMINE AND SEROTONINE
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
EP2611782A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
EP2611433A2 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
KR20180118801A (ko) 2010-09-01 2018-10-31 에자이 알앤드디 매니지먼트 가부시키가이샤 체중 관리에 유용한 5-ｈｔ2ｃ 작동제의 변형-방출 투여 형태
SG188365A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
KR20190128001A (ko) 2012-10-09 2019-11-13 에자이 알앤드디 매니지먼트 가부시키가이샤 체중 관리 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5233687A (en) * 1975-09-11 1977-03-14 Shionogi & Co Ltd Process for preparation of 1,5-dihydro-2h-1,4-benzodiazepine-2-on deri vatives
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound

Also Published As

Publication number Publication date
DE3370621D1 (en) 1987-05-07
JPH0365342B2 (da) 1991-10-11
GR78291B (da) 1984-09-26
EP0096838B1 (en) 1987-04-01
IE55404B1 (en) 1990-09-12
PT76864A (en) 1983-07-01
FI78473B (fi) 1989-04-28
FI832092A0 (fi) 1983-06-10
KR900001214B1 (ko) 1990-02-28
PT76864B (en) 1986-02-27
ES8503666A1 (es) 1985-03-01
FI832092L (fi) 1983-12-15
IL68964A (en) 1988-03-31
AU1576483A (en) 1983-12-22
ATE26263T1 (de) 1987-04-15
HU190902B (en) 1986-12-28
IE831384L (en) 1983-12-14
FI78473C (fi) 1989-08-10
ZA834309B (en) 1984-03-28
US4988690A (en) 1991-01-29
AU570920B2 (en) 1988-03-31
KR840005103A (ko) 1984-11-03
JPS595165A (ja) 1984-01-12
IL68964A0 (en) 1983-10-31
DK270983A (da) 1983-12-15
ES523191A0 (es) 1985-03-01
CA1214460A (en) 1986-11-25
EP0096838A1 (en) 1983-12-28

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Legal Events

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AHS Application shelved for other reasons than non-payment