DK239685D0 - Substituerede pyrrolidinoner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne - Google Patents

Substituerede pyrrolidinoner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne

Info

Publication number: DK239685D0
Authority: DK; Denmark
Prior art keywords: group; carbon atoms; substituted; alkyl group; chained
Prior art date: 1984-05-30

Application number

DK239685A

Other languages

English (en)

Other versions

DK239685A (da

Inventor

Karl-Heinz Weber

Claus Schneider

Gerard Walter

Dieter Hinzen

Franz Josef Kuhn

Erich Lehr

Helmut Ensinger

Wolfgang Troeger

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-30

Filing date

1985-05-29

Publication date

1985-05-29

1985-05-29 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1985-05-29 Publication of DK239685D0 publication Critical patent/DK239685D0/da

1985-12-01 Publication of DK239685A publication Critical patent/DK239685A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK239685A 1984-05-30 1985-05-29 Substituerede pyrrolidinoner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne DK239685A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19843420193 DE3420193A1 (de)	1984-05-30	1984-05-30	Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel

Publications (2)

Publication Number	Publication Date
DK239685D0 true DK239685D0 (da)	1985-05-29
DK239685A DK239685A (da)	1985-12-01

Family

ID=6237240

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK239685A DK239685A (da)	1984-05-30	1985-05-29	Substituerede pyrrolidinoner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne

Country Status (22)

Country	Link
US (4)	US4670456A (da)
EP (1)	EP0163260B1 (da)
JP (1)	JPS6168A (da)
KR (1)	KR850008343A (da)
AT (1)	ATE36151T1 (da)
AU (1)	AU581438B2 (da)
CA (1)	CA1255664A (da)
CS (1)	CS261883B2 (da)
DD (1)	DD235256A5 (da)
DE (2)	DE3420193A1 (da)
DK (1)	DK239685A (da)
ES (4)	ES8607926A1 (da)
FI (1)	FI78462C (da)
GR (1)	GR851306B (da)
HU (1)	HU193393B (da)
IL (1)	IL75339A (da)
NO (1)	NO852133L (da)
NZ (1)	NZ212241A (da)
PL (1)	PL144921B1 (da)
PT (1)	PT80545B (da)
SU (1)	SU1360583A3 (da)
ZA (1)	ZA854072B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3336024A1 (de) *	1983-10-04	1985-04-18	Boehringer Ingelheim KG, 6507 Ingelheim	4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
FR2597100A1 (fr) *	1986-01-21	1987-10-16	Nippon Shinyaku Co Ltd	Derives du pyroglutamide
US4960776A (en) *	1987-01-28	1990-10-02	A. H. Robins Company, Inc.	4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides
CA1305148C (en) *	1987-08-19	1992-07-14	Hiromu Matsumura	Carbamoylpyrrolidone derivatives and drugs for senile dementia
US4833139A (en) *	1988-01-25	1989-05-23	Hoechst-Roussel Pharmaceuticals, Inc.	Enhancing cholinergic activity with 5-substituted 1-[4-(1-pyrrolidinyl)-2-butynyl]-2-pyrrolidinones and related compounds
EP0342613B1 (en) *	1988-05-20	1992-11-11	ZAMBON GROUP S.p.A.	Compounds with central analgesic activity, process for their preparation and pharmaceutical compositions containing them
JPH02137427A (ja) *	1988-11-18	1990-05-25	Du Pont Opt Electron Kk	光電気的接続装置及び光コンセント
US4981974A (en) *	1989-05-08	1991-01-01	Gaf Chemicals Corporation	Polymerizable pyrrolidonyl oxazoline monomers
KR101419554B1 (ko) *	2006-03-13	2014-07-17	교린 세이야꾸 가부시키 가이샤	Ｇｓｋ３ 억제제로서 아미노퀴놀론
JP5426552B2 (ja) *	2007-09-11	2014-02-26	杏林製薬株式会社	Ｇｓｋ−３阻害剤としてのシアノアミノキノロン及びテトラゾロアミノキノロン
KR20100093104A (ko) *	2007-12-05	2010-08-24	아스트라제네카 아베	항비만제로서의 피페라진
CN102015668A (zh)	2007-12-05	2011-04-13	阿斯利康(瑞典)有限公司	用作瘦蛋白受体调节剂的哌嗪衍生物及其用途
EP2321276A1 (en) *	2008-06-04	2011-05-18	AstraZeneca AB	New compounds vii
EP2406266B1 (en) *	2009-03-11	2013-12-25	Kyorin Pharmaceutical Co., Ltd.	7-cycloalkylaminoquinolones as gsk-3 inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2838914A (en) *	1957-07-03	1958-06-17	Olin Mathieson	Isonicotinic acid hydrazide derivatives
GB1309692A (en) *	1970-02-13	1973-03-14	Ucb Sa	N-substituted lactams
GB1039113A (en) *	1964-08-06	1966-08-17	Ucb Sa	New n-substituted lactams
JPS4924916B1 (da) *	1970-08-14	1974-06-26
FR2387218A1 (fr) *	1977-04-15	1978-11-10	Ile De France	Nouveaux n-(1'-ethyl 2'-oxo 5'-pyrrolidinyl methyl) benzamides, leurs procedes de preparation et leur application comme modificateurs du comportement
CU21107A3 (es) *	1978-02-10	1988-02-01	Hoffmann La Roche	Pyrrolidines derivatives
DE3326724A1 (de) *	1983-07-25	1985-02-07	Boehringer Ingelheim KG, 6507 Ingelheim	In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte
DE3336024A1 (de) *	1983-10-04	1985-04-18	Boehringer Ingelheim KG, 6507 Ingelheim	4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
GB8412358D0 (en) *	1984-05-15	1984-06-20	Ucb Sa	Pharmaceutical composition
US4670436A (en) *	1986-08-29	1987-06-02	Mcneilab, Inc.	Hypoglycemic 5-substituted pyrrolidinylidene compounds, compositions and use

1984
- 1984-05-30 DE DE19843420193 patent/DE3420193A1/de not_active Withdrawn
1985
- 1985-05-23 DE DE8585106343T patent/DE3564105D1/de not_active Expired
- 1985-05-23 AT AT85106343T patent/ATE36151T1/de not_active IP Right Cessation
- 1985-05-23 EP EP85106343A patent/EP0163260B1/de not_active Expired
- 1985-05-24 US US06/738,152 patent/US4670456A/en not_active Expired - Fee Related
- 1985-05-28 GR GR851306A patent/GR851306B/el unknown
- 1985-05-28 PL PL1985253668A patent/PL144921B1/pl unknown
- 1985-05-29 CS CS853854A patent/CS261883B2/cs unknown
- 1985-05-29 FI FI852130A patent/FI78462C/fi not_active IP Right Cessation
- 1985-05-29 ZA ZA854072A patent/ZA854072B/xx unknown
- 1985-05-29 SU SU853900955A patent/SU1360583A3/ru active
- 1985-05-29 KR KR1019850003709A patent/KR850008343A/ko not_active Application Discontinuation
- 1985-05-29 HU HU852056A patent/HU193393B/hu not_active IP Right Cessation
- 1985-05-29 ES ES543592A patent/ES8607926A1/es not_active Expired
- 1985-05-29 IL IL75339A patent/IL75339A/xx unknown
- 1985-05-29 PT PT80545A patent/PT80545B/pt unknown
- 1985-05-29 DD DD85276752A patent/DD235256A5/de not_active IP Right Cessation
- 1985-05-29 NZ NZ212241A patent/NZ212241A/xx unknown
- 1985-05-29 CA CA000482660A patent/CA1255664A/en not_active Expired
- 1985-05-29 NO NO852133A patent/NO852133L/no unknown
- 1985-05-29 DK DK239685A patent/DK239685A/da not_active Application Discontinuation
- 1985-05-30 JP JP60117657A patent/JPS6168A/ja active Granted
- 1985-05-30 AU AU43170/85A patent/AU581438B2/en not_active Ceased
1986
- 1986-02-26 ES ES552410A patent/ES8707927A1/es not_active Expired
- 1986-02-26 ES ES552409A patent/ES8801200A1/es not_active Expired
- 1986-02-26 ES ES552411A patent/ES8707928A1/es not_active Expired
- 1986-12-18 US US06/943,532 patent/US4762832A/en not_active Expired - Fee Related
1988
- 1988-04-20 US US07/183,819 patent/US4857528A/en not_active Expired - Fee Related
1989
- 1989-06-12 US US07/365,169 patent/US4891378A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK239685A (da)	1985-12-01
NZ212241A (en)	1989-07-27
DE3564105D1 (en)	1988-09-08
US4857528A (en)	1989-08-15
FI78462C (fi)	1989-08-10
US4762832A (en)	1988-08-09
PT80545A (de)	1985-06-01
PT80545B (de)	1987-04-06
ES543592A0 (es)	1986-06-01
DE3420193A1 (de)	1985-12-05
ZA854072B (en)	1987-02-25
CS385485A2 (en)	1988-06-15
ES552411A0 (es)	1987-09-01
PL253668A1 (en)	1986-05-20
EP0163260B1 (de)	1988-08-03
PL144921B1 (en)	1988-07-30
CA1255664A (en)	1989-06-13
GR851306B (da)	1985-11-25
FI852130A0 (fi)	1985-05-29
IL75339A0 (en)	1985-09-29
IL75339A (en)	1988-07-31
HU193393B (en)	1987-09-28
ES8707928A1 (es)	1987-09-01
ES552409A0 (es)	1987-12-16
ES552410A0 (es)	1987-09-01
HUT37751A (en)	1986-02-28
AU581438B2 (en)	1989-02-23
SU1360583A3 (ru)	1987-12-15
JPS6168A (ja)	1986-01-06
CS261883B2 (en)	1989-02-10
ES8801200A1 (es)	1987-12-16
FI852130L (fi)	1985-12-01
KR850008343A (ko)	1985-12-16
JPH0517904B2 (da)	1993-03-10
US4891378A (en)	1990-01-02
ATE36151T1 (de)	1988-08-15
US4670456A (en)	1987-06-02
FI78462B (fi)	1989-04-28
EP0163260A1 (de)	1985-12-04
ES8607926A1 (es)	1986-06-01
NO852133L (no)	1985-12-02
DD235256A5 (de)	1986-04-30
ES8707927A1 (es)	1987-09-01
AU4317085A (en)	1985-12-05

Legal Events

Date	Code	Title	Description
1991-01-21	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK239685D0 (da)	1985-05-29	Substituerede pyrrolidinoner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne
ES8104275A1 (es)	1981-04-01	Un metodo para la preparacion de derivados de ftalimidina
ES8503355A1 (es)	1985-02-16	Procedimiento de preparacion de nuevas sales de derivados organofosforados
AT389108B (de)	1989-10-25	Neue pyridazinonderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
MX9207491A (es)	1993-07-01	Compuestos de 1-(arilalquilaminoalquil)imidazol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
NZ217276A (en)	1988-10-28	Bicyclic heterocyclic compounds and pharmaceutical compositions
DK104488D0 (da)	1988-02-26	Acetamider afledt af 2,3-dihydro-3-phenyl-2-benzofuranon, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem
DK356287D0 (da)	1987-07-09	2,6-piperazindionderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse
DK513281A (da)	1982-05-21	Fremgangsaade til fremstilling af 3-thiovinylcephalosproner
DK553482A (da)	1983-06-15	Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider
ES498150A0 (es)	1982-04-16	Un procedimiento para la preparacion de nuevos eteres de 1-(2-propiniloxi)-2-amino-3-propanol.
ES8600204A1 (es)	1985-10-01	Procedimiento de preparacion de nuevos deridados de alfa-etibenzol con un grupo amino propanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias.
ES515201A0 (es)	1983-11-01	"procedimiento para la fabricacion de derivados n- susbtituidos de la tetrahidroisftalimida".