DK2376121T4 - Slidgigtbehandling - Google Patents
Slidgigtbehandling Download PDFInfo
- Publication number
- DK2376121T4 DK2376121T4 DK09833924.5T DK09833924T DK2376121T4 DK 2376121 T4 DK2376121 T4 DK 2376121T4 DK 09833924 T DK09833924 T DK 09833924T DK 2376121 T4 DK2376121 T4 DK 2376121T4
- Authority
- DK
- Denmark
- Prior art keywords
- osteoarthritis treatment
- osteoarthritis
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/243—Colony Stimulating Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13967908P | 2008-12-22 | 2008-12-22 | |
US16448609P | 2009-03-30 | 2009-03-30 | |
PCT/AU2009/001672 WO2010071924A1 (en) | 2008-12-22 | 2009-12-21 | Osteoarthritis treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
DK2376121T3 DK2376121T3 (da) | 2016-05-30 |
DK2376121T4 true DK2376121T4 (da) | 2021-08-16 |
Family
ID=42286786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09833924.5T DK2376121T4 (da) | 2008-12-22 | 2009-12-21 | Slidgigtbehandling |
Country Status (19)
Country | Link |
---|---|
US (4) | US9243061B2 (da) |
EP (2) | EP2376121B2 (da) |
JP (3) | JP5727379B2 (da) |
KR (2) | KR101799264B1 (da) |
CN (2) | CN106397591A (da) |
AU (1) | AU2009329814B2 (da) |
BR (1) | BRPI0918356B1 (da) |
CA (1) | CA2746827C (da) |
CY (1) | CY1117698T1 (da) |
DK (1) | DK2376121T4 (da) |
ES (2) | ES2886063T3 (da) |
HK (1) | HK1226938A1 (da) |
HR (1) | HRP20160577T4 (da) |
HU (1) | HUE028615T2 (da) |
PL (1) | PL2376121T5 (da) |
RU (2) | RU2011127334A (da) |
SI (2) | SI2376121T1 (da) |
SM (1) | SMT201600156B (da) |
WO (1) | WO2010071924A1 (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2011127334A (ru) | 2008-12-22 | 2013-01-27 | Де Юниверсити Оф Мельбурн | Лечение остеоартрита |
EP3381471B1 (en) | 2008-12-22 | 2024-03-20 | The University of Melbourne | Pain treatment |
KR20150056846A (ko) | 2012-09-20 | 2015-05-27 | 모르포시스 아게 | 류마티스 관절염에 대한 치료 |
DE102013222200A1 (de) * | 2013-10-31 | 2015-08-27 | Osram Opto Semiconductors Gmbh | Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements |
IL301622A (en) * | 2017-08-14 | 2023-05-01 | Zynerba Pharmaceuticals Inc | Methods for treating degenerative joint disease with cannabidiol gel through the skin |
CN110075304B (zh) * | 2019-05-29 | 2020-02-11 | 四川大学华西医院 | 一种治疗骨关节炎的药物组合物及其用途 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
WO1991001330A1 (en) | 1989-07-14 | 1991-02-07 | Schering Corporation | Antagonists of gm-csf derived from the carboxyl terminus |
DK0486572T3 (da) | 1989-08-11 | 1998-05-04 | Amrad Corp Ltd | Forbedringer i granulocyt-makrofag-kolonistimulerende faktorreceptor og derivater deraf |
US5747032A (en) | 1990-08-10 | 1998-05-05 | Amrad Corporation Limited | Monoclonal antibody to human granulocyte macrophage colony stimulating factor |
CA2149881A1 (en) | 1992-11-19 | 1994-05-26 | Paul T. Jubinsky | Antibodies for gm-csf receptor and uses thereof |
WO1997008320A1 (en) | 1995-08-18 | 1997-03-06 | Morphosys Gesellschaft Für Proteinoptimierung Mbh | Protein/(poly)peptide libraries |
AUPP525198A0 (en) | 1998-08-13 | 1998-09-03 | Medvet Science Pty. Ltd. | Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof |
US7108852B2 (en) | 2000-03-20 | 2006-09-19 | Warner-Lambert Company Llc | Methods of treating inflammation using antibodies to M-CSF |
US7455836B2 (en) * | 2000-05-08 | 2008-11-25 | The University Of Melbourne | Method of treatment and agents useful for same |
US20060067938A1 (en) * | 2001-10-26 | 2006-03-30 | Sherif Daouti | Methods for the treatment of osteoarthritis and compositions thereof |
US7714113B2 (en) | 2002-02-13 | 2010-05-11 | Ludwig Institute For Cancer Research | Fusion proteins of humanized g250 specific antibodies and uses thereof |
US20040241755A1 (en) * | 2003-06-02 | 2004-12-02 | Pfizer Inc. | Human cell assay to determine effect of sample compounds on Col2 enhancer expression |
ATE464908T1 (de) | 2004-02-11 | 2010-05-15 | Warner Lambert Co | Verfahren zur behandlung von osteoarthritis mit anti-il-6 antikörpern |
ES2465141T3 (es) * | 2004-03-31 | 2014-06-05 | Kazuwa Nakao | Remedio o medicamento preventivo para la artritis |
ATE435238T1 (de) | 2004-05-05 | 2009-07-15 | Micromet Ag | Herstellung eines einkettigen fv antikörperfragments |
JP2008510168A (ja) * | 2004-08-18 | 2008-04-03 | アメリカ合衆国 | 骨関節炎のバイオマーカー |
US20060040258A1 (en) | 2004-08-23 | 2006-02-23 | Huiyan Guo | Water-soluble conjugates and methods of preparation |
PL1874819T3 (pl) | 2005-04-18 | 2015-10-30 | Amgen Res Munich Gmbh | Przeciwciała neutralizujące ludzki czynnik stymulujący wzrost kolonii granulocytów i makrofagów |
AU2006249062B2 (en) * | 2005-05-18 | 2012-12-20 | Morphosys Ag | Anti-GM-CSF antibodies and uses therefor |
JP4736037B2 (ja) | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトgm−csfに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
EP1957537A2 (en) * | 2005-12-01 | 2008-08-20 | Domantis Limited | Competitive domain antibody formats that bind interleukin 1 receptor type 1 |
KR101486183B1 (ko) * | 2006-02-08 | 2015-01-28 | 모르포테크, 인크. | 항원성 gm-csf 펩티드 및 gm-csf에 대한 항체 |
SI1999152T1 (sl) * | 2006-03-27 | 2013-02-28 | Medimmune Limited | Vezni äślen za gm-csf receptor |
US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
BRPI0719109A2 (pt) * | 2006-11-21 | 2013-12-10 | Kalobios Pharmaceuticals Inc | Métodos para tratar doenças inflamatórias crônicas usando um antagonista de gm-csf |
WO2008080134A2 (en) * | 2006-12-22 | 2008-07-03 | Rigel Pharmaceuticals, Inc. | 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors |
EP2160407A4 (en) | 2007-05-23 | 2011-07-27 | Crc For Asthma And Airways Ltd | NEUTRALIZING ANTIBODIES |
TW200918553A (en) | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
WO2009042854A1 (en) * | 2007-09-26 | 2009-04-02 | Musculoskeletal Research Llc | Ion-channel regulator compositions and methods of using same |
EP2217626A4 (en) | 2007-11-12 | 2011-06-22 | Crc For Asthma And Airways Ltd | EPITOP FOR NEUTRALIZING ANTIBODIES |
EP2215119B1 (en) | 2007-11-13 | 2012-12-26 | Evec Inc. | Monoclonal antibodies that bind to hgm-csf and medical compositions comprising same |
MX2010010503A (es) | 2008-03-24 | 2010-11-09 | Abbott Biotech Ltd | Metodos y composiciones para tratar perdida osea. |
NZ588850A (en) | 2008-04-28 | 2012-12-21 | Kalobios Pharmaceuticals Inc | Antibodies to granulocyte-macrophage colony-stimulating factor |
RU2011127334A (ru) | 2008-12-22 | 2013-01-27 | Де Юниверсити Оф Мельбурн | Лечение остеоартрита |
EP3381471B1 (en) | 2008-12-22 | 2024-03-20 | The University of Melbourne | Pain treatment |
CN102459340A (zh) | 2009-04-23 | 2012-05-16 | 特罗科隆科学有限公司 | 粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体 |
-
2009
- 2009-12-21 RU RU2011127334/15A patent/RU2011127334A/ru unknown
- 2009-12-21 PL PL09833924T patent/PL2376121T5/pl unknown
- 2009-12-21 ES ES15194091T patent/ES2886063T3/es active Active
- 2009-12-21 CN CN201610822096.9A patent/CN106397591A/zh active Pending
- 2009-12-21 US US13/140,467 patent/US9243061B2/en active Active
- 2009-12-21 JP JP2011541030A patent/JP5727379B2/ja active Active
- 2009-12-21 AU AU2009329814A patent/AU2009329814B2/en active Active
- 2009-12-21 SI SI200931446A patent/SI2376121T1/sl unknown
- 2009-12-21 BR BRPI0918356-6A patent/BRPI0918356B1/pt active IP Right Grant
- 2009-12-21 HU HUE09833924A patent/HUE028615T2/en unknown
- 2009-12-21 WO PCT/AU2009/001672 patent/WO2010071924A1/en active Application Filing
- 2009-12-21 EP EP09833924.5A patent/EP2376121B2/en active Active
- 2009-12-21 EP EP15194091.3A patent/EP3056217B1/en active Active
- 2009-12-21 CA CA2746827A patent/CA2746827C/en active Active
- 2009-12-21 CN CN2009801516359A patent/CN102271705A/zh active Pending
- 2009-12-21 KR KR1020117017015A patent/KR101799264B1/ko active IP Right Grant
- 2009-12-21 SI SI200931446T patent/SI2376121T2/sl unknown
- 2009-12-21 KR KR1020177032850A patent/KR101898982B1/ko active IP Right Grant
- 2009-12-21 RU RU2016102339A patent/RU2712273C2/ru active
- 2009-12-21 DK DK09833924.5T patent/DK2376121T4/da active
- 2009-12-21 ES ES09833924T patent/ES2572368T5/es active Active
-
2015
- 2015-02-20 JP JP2015031198A patent/JP2015143233A/ja active Pending
- 2015-12-18 US US14/975,024 patent/US20160185868A1/en not_active Abandoned
-
2016
- 2016-05-18 CY CY20161100433T patent/CY1117698T1/el unknown
- 2016-05-30 HR HRP20160577TT patent/HRP20160577T4/hr unknown
- 2016-06-01 SM SM201600156T patent/SMT201600156B/it unknown
- 2016-12-06 HK HK16113893A patent/HK1226938A1/zh unknown
-
2017
- 2017-06-12 JP JP2017114806A patent/JP6458086B2/ja active Active
- 2017-11-13 US US15/811,279 patent/US20180066062A1/en not_active Abandoned
-
2020
- 2020-03-31 US US16/836,464 patent/US20200247895A1/en not_active Abandoned
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