DK2364742T3 - Indretning til lægemiddelafgivelse - Google Patents

Indretning til lægemiddelafgivelse Download PDF

Info

Publication number
DK2364742T3
DK2364742T3 DK10184272.2T DK10184272T DK2364742T3 DK 2364742 T3 DK2364742 T3 DK 2364742T3 DK 10184272 T DK10184272 T DK 10184272T DK 2364742 T3 DK2364742 T3 DK 2364742T3
Authority
DK
Denmark
Prior art keywords
dose
piston rod
delivery
predetermined
drug
Prior art date
Application number
DK10184272.2T
Other languages
English (en)
Inventor
Lennart Brunnberg
Anders Karlsson
Victor Kronestedt
Stephan Olson
Tomas Deurell
Original Assignee
Shl Group Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42543328&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2364742(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/140,989 external-priority patent/US20060276753A1/en
Priority claimed from US11/282,593 external-priority patent/US9011386B2/en
Application filed by Shl Group Ab filed Critical Shl Group Ab
Application granted granted Critical
Publication of DK2364742T3 publication Critical patent/DK2364742T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0073—Mechanical counters having a display or indicator on a ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0076—Mechanical counters having a display or indicator on a drum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (11)

1. Indretning (2; 100) til afgivelse af forudbestemte doser af flydende lægemiddel, hvilken indretning er indrettet til at være i en lægemiddelafgivelsesstilling og i en ikke-lægemiddelafgivelsesstilling, og indretningen er indrettet til at omfatte: - en kassette (10; 103), der er indrettet til at indeholde det flydende lægemiddel, og et stempel, der er anbragt tætnende og glidbart i kassetten; - et energiakkumulerende organ (26; 114) indrettet til akkumulering af energi i mindst ét forudbestemt trin, når indretningen er i den ikke-lægemiddelafgivende stilling; - en aflang, gevindforsynet stempelstang (16; 126) indrettet til anbringelse inden i indretningen; - et stempelstangsdrivorgan (40; 47; 128) i indgreb med den gevindforsynede stempelstang (16; 126) og indrettet til at være i en drivstilling, når indretningen er i lægemiddelafgivelsesstillingen, og indrettet til at være i en ikke-drivstilling, når indretningen er i den ikke-lægemiddelafgivende stilling, hvorved drejningen af stempelstangsdrivorganet (40; 47; 128) som følge af det energiakkumulerende organs (26; 114) udgangsmoment driver den gevindforsynede stempelstang (16; 126) og tillader stangen, som er i kontakt med stemplet, at blive drevet mod den proksimale ende af kassetten med en forudbestemt afstand og udstøder en forudbestemt dosis af det flydende lægemiddel fra kassetten; kendetegnet ved, at det energiakkumulerende organ (26; 114) er en flad spiralfjeder.
2. Indretning ifølge krav 1, kendetegnet ved, at et kassettehus (8; 101) er koblet til det ydre hylster (48), og hvor den indvendige del af kassettehuset (8; 101), som er i indgreb med stempelstangen, er forsynet med dele (52) i indgreb med langstrakte dele (53) på stempelstangen, og hvor den indvendige del af stempelstangsdrivorganet (40; 128), som er i indgreb med stempelstangen, er forsynet med et gevind, der passer til gevindet på stempelstangen, således at drejningen af stempelstangsdrivorganet (40; 128) vil drive stempelstangen mod den proksimale ende af kassetten den forudbestemte afstand uden drejning.
3. Indretning ifølge krav 1, kendetegnet ved, at den indvendige del af stempelstangsdrivorganet (47), som står i indgreb med stempelstangen, er forsynet med dele (52), der griber ind i langsgående dele (53) på stempelstangen, og at stempelstangsdrivorganet (47) er indrettet til at rumme et ikke-roterende leje (41), hvor den indvendige del (43) af det ikke-roterende leje (41) er forsynet med et gevind, der passer til gevindet på stempelstangen, således at stempelstangen bevæger sig mod den proksimale ende af kassetten den forudbestemte afstand under drejning.
4. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at et dosisindstillingsorgan (4; 104) er indrettet til at blive drejet mindst ét forudbestemt trin, når indretningen står i den ikke-lægemiddelafgivende stilling, for at øge den akkumulerede energi i det energiakkumulerende organ med mindst ét trin, og også er indrettet til at blive trukket mod den distale ende af afgivelsesindretningen for at frigive den akkumulerede energi i det energiakkumulerende organ til lukning af en dosis.
5. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at den udvendige del af stempelstangsdrivorganet (40; 47; 128) er udformet således, at det i sin proksimale ende er forsynet med udad ragende flanger (42; 302; 130), der er i indgreb med indad ragende stoporganer (51; 306; 111), der er tilvejebragt på den indvendige del af en aktiveringsbøsning (50; 109), når indretningen står i den ikke-lægemiddelafgivende stilling.
6. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at de udad ragende flanger (302) kan være udformet med et antal dosistrinfremspring (302a, 302b), der er jævnt fordelt langs omkredsen af den proksimale del af stempelstangsdrivorganet (47), således at hvert dosistrin afgiver samme forudbestemte mængde lægemiddel.
7. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at indretningen under lægemiddelafgivelse er indrettet til at blive sat i den ikke-lægemiddelafgivende stilling, før hele den indstillede dosis er afgivet, hvorpå stempelstangen stopper sin bevægelse mod den proksimale ende af kassetten, og at indretningen derefter er beregnet til at sættes i den lægemiddelafgivende stilling, hvorefter stempelstangen fortsætter at bevæge sig den forudbestemte afstand mod den proksimale ende af indretningen.
8. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at indretningen er indrettet til at blive forbundet til et lægemiddeladministreringsorgan i form af et mund- eller næsestykke, som patienten anbringer i munden eller næsen, hvorved den forudbestemte dosis lægemiddel inhaleres af patienten, når afgivelsesindretningen er i lægemiddelafgivelsesstillingen.
9. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at indretningen er beregnet til at blive forbundet til et lægemiddelafgivelsesorgan i form af en dyse, hvorved den forudbestemte dosis lægemiddel sprøjtes i øjet eller på huden af patienten, når afgivelsesindretningen er i lægemiddelafgivelsesstillingen.
10. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at indretningen er beregnet til at blive forbundet til et lægemiddeladministreringsorgan i form af et organ, der afgiver den forudbestemte dosis lægemiddel i form af mindst én dråbe, når afgivelsesindretningen er i lægemiddelafgivelsesstillingen.
11. Indretning ifølge ethvert af de foregående krav, kendetegnet ved, at indretningen er beregnet til at blive forbundet til et lægemiddeladministreringsorgan i form af en kanyle til injektion af den forudbestemte dosis lægemiddel ind i patientens krop, når afgivelsesindretningen er i lægemiddelafgivelsesstillingen.
DK10184272.2T 2005-06-01 2006-05-22 Indretning til lægemiddelafgivelse DK2364742T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/140,989 US20060276753A1 (en) 2005-06-01 2005-06-01 Device for delivering medicament
EP05104734.8A EP1728529B2 (en) 2005-06-01 2005-06-01 Device for delivering medicament
US11/282,593 US9011386B2 (en) 2005-06-01 2005-11-21 Device for delivering medicament
EP06733519.0A EP1885415B1 (en) 2005-06-01 2006-05-22 Device for delivering medicament
PCT/SE2006/050150 WO2006130100A1 (en) 2005-06-01 2006-05-22 Device for delivering medicament

Publications (1)

Publication Number Publication Date
DK2364742T3 true DK2364742T3 (da) 2019-03-04

Family

ID=42543328

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06733519.0T DK1885415T3 (da) 2005-06-01 2006-05-22 Indretning til afgivelse af et medikament
DK10184272.2T DK2364742T3 (da) 2005-06-01 2006-05-22 Indretning til lægemiddelafgivelse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06733519.0T DK1885415T3 (da) 2005-06-01 2006-05-22 Indretning til afgivelse af et medikament

Country Status (5)

Country Link
EP (3) EP1885415B1 (da)
JP (1) JP5026412B2 (da)
DK (2) DK1885415T3 (da)
ES (1) ES2423199T3 (da)
WO (1) WO2006130100A1 (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040103930A (ko) 2002-02-11 2004-12-09 앤태어스 파머, 인코퍼레이티드 피내 주사기
PT1850892T (pt) 2005-01-24 2019-02-08 Antares Pharma Inc Injector a jacto com seringa pré-cheia
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
WO2008031236A1 (de) * 2006-09-15 2008-03-20 Tecpharma Licensing Ag Spritzwassergeschütztes injektionsgerät
WO2009097934A1 (en) * 2008-02-05 2009-08-13 Shl Group Ab Injection device with pre-activation means
ES2752152T3 (es) 2008-03-10 2020-04-03 Antares Pharma Inc Dispositivo de seguridad para inyector
JP5611208B2 (ja) 2008-08-05 2014-10-22 アンタレス・ファーマ・インコーポレーテッド 多数回服用量の注射装置
ES2567715T3 (es) * 2008-11-17 2016-04-26 Becton Dickinson And Company Dispositivo de fuerza adicional para pluma de administración de medicamento para inyección de medicación intradérmica
AU2010226442A1 (en) 2009-03-20 2011-10-13 Antares Pharma, Inc. Hazardous agent injection system
US9623187B2 (en) * 2009-06-01 2017-04-18 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US9750900B2 (en) 2009-10-08 2017-09-05 Shl Group Ab Metered liquid droplet inhaler
GB0918145D0 (en) * 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
PL215310B1 (pl) * 2009-10-30 2013-11-29 Kappa Medilab Spolka Z Ograniczona Odpowiedzialnoscia Automatyczny aplikator, zwlaszcza do insuliny
EP2536451B1 (en) * 2010-02-18 2018-03-28 Sanofi-Aventis Deutschland GmbH Auto-injector with a torsion spring
EP2560712A4 (en) * 2010-04-19 2017-12-13 SHL Group AB A self-administration medicament delivery device
US9072839B2 (en) * 2010-11-29 2015-07-07 Sanofi-Aventis Deutschland Gmbh Automatic delivery device with triggering mechanism
EP2468329A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
EP2474332A1 (en) * 2011-01-07 2012-07-11 Sanofi-Aventis Deutschland GmbH Cartridge holder for an injection device
WO2012173553A1 (en) * 2011-06-17 2012-12-20 Shl Group Ab Injection device
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
WO2013078078A1 (en) * 2011-11-22 2013-05-30 West Pharmaceutical Services, Inc. Linear drive and clutch assembly
PL220720B1 (pl) * 2012-02-08 2015-12-31 Copernicus Spółka Z Ograniczoną Odpowiedzialnością Urządzenie wstrzykujące z mechanizmem resetu dawki
KR20150003179A (ko) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 분리력 특징을 가진 사전충전형 주사기
EP2825228B1 (en) * 2012-03-16 2020-06-24 SHL Medical AG Medicament delivery device
EP2833944A4 (en) 2012-04-06 2016-05-25 Antares Pharma Inc ADMINISTRATION OF TESTOSTERONE COMPOSITIONS BY NEEDLE-SUPPORTED NOZZLE INJECTION
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
CH706567A2 (de) 2012-05-16 2013-11-29 Tecpharma Licensing Ag Verbesserte Vorrichtung zum Einstellen einer Dosis mit einem Begrenzungsmechanismus für ein Gerät zur Verabreichung eines Produkts.
JP2015525583A (ja) * 2012-06-29 2015-09-07 ノボ・ノルデイスク・エー／エス ばね駆動式の注射装置
PT2953667T (pt) 2013-02-11 2020-01-28 Antares Pharma Inc Dispositivo de injeção a jato auxiliado por agulha tendo força de gatilho reduzida
ES2742046T3 (es) 2013-03-11 2020-02-12 Antares Pharma Inc Inyector de dosis con sistema de piñón
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
WO2014170267A1 (en) * 2013-04-19 2014-10-23 Novo Nordisk A/S Drug delivery device with compact power unit
EP3132821B1 (en) 2015-03-03 2018-12-19 Innovative Precision Instruments Limited Drug information detection apparatus and drug information detection type injection apparatus
EP3064241A1 (en) * 2015-03-06 2016-09-07 Carebay Europe Ltd. Power supply mechanism
EP3288613B1 (en) 2015-04-29 2021-12-08 Novo Nordisk A/S Drug delivery device with spring mechanism
PL414382A1 (pl) 2015-10-15 2017-04-24 Copernicus Spółka Z Ograniczoną Odpowiedzialnością Mechanizm nastawczy, w szczególności do dozowania
TW201726193A (zh) 2015-11-27 2017-08-01 賽諾菲阿凡提斯德意志有限公司 自動注射器（二）
PL227678B1 (pl) 2015-12-22 2018-01-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ
EP3108914B1 (en) 2016-07-07 2019-02-27 Copernicus SP. Z O.O. Injection device for delivering a defined number of equal doses of a liquid substance
US9636464B1 (en) 2016-08-01 2017-05-02 Innovative Precision Instruments Limited Drug delivery device and a drug information detection device
JP7200134B2 (ja) 2017-06-08 2023-01-06 アムジエン・インコーポレーテツド トルク駆動式薬物送達デバイス
US11554215B2 (en) 2017-06-08 2023-01-17 Novartis Ag Injection device and injection solution transferring system
PL232651B1 (pl) 2017-07-18 2019-07-31 Copernicus Spolka Z Ograniczona Odpowiedzialnoscia Sprzęgło z systemem blokowania dla medycznego urządzenia wstrzykującego

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52621B1 (en) 1981-02-12 1988-01-06 Turner Robert Charles Dose metering plunger devices for use with syringes
GB8809115D0 (en) * 1988-04-18 1988-05-18 Turner R C Syringes
US4921487A (en) 1988-09-21 1990-05-01 Compagnie Financiere Saint. Nicolas External device for injecting medicine
DK175491D0 (da) * 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5320609A (en) * 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
JP2003516193A (ja) 1999-12-09 2003-05-13 ノボ ノルディスク アクティーゼルスカブ 注入装置
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
US6899699B2 (en) 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
US20030055380A1 (en) 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
DE20209051U1 (de) 2001-12-21 2003-04-24 Disetronic Licensing Ag, Burgdorf Injektionsgerät mit endpositionsblockiertem Dosiseinstellglied
DE10240166A1 (de) 2002-08-30 2004-03-18 Disetronic Licensing Ag Vorrichtung zur kontrollierten Ausschüttung einer injizierbaren Flüssigkeit
DE10240165A1 (de) 2002-08-30 2004-03-18 Disetronic Licensing Ag Vorrichtung zum dosierten Ausstoßen eines flüssigen Wirkstoffes und Infusionspumpe
DE10343548B4 (de) * 2003-09-19 2008-03-27 Tecpharma Licensing Ag Vorrichtung für eine dosierte Abgabe eines injizierbaren Produkts
DE102004063644A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Drehfederantrieb

Also Published As

Publication number Publication date
EP2364742A3 (en) 2012-11-07
EP2364742A2 (en) 2011-09-14
EP1885415A1 (en) 2008-02-13
EP2484395B1 (en) 2023-11-08
JP5026412B2 (ja) 2012-09-12
ES2423199T3 (es) 2013-09-18
EP2364742B1 (en) 2018-11-14
EP1885415B1 (en) 2013-05-15
EP1885415A4 (en) 2012-02-22
EP2484395A3 (en) 2013-04-17
JP2008541932A (ja) 2008-11-27
EP2484395A2 (en) 2012-08-08
WO2006130100A1 (en) 2006-12-07
DK1885415T3 (da) 2013-08-05

Similar Documents

Publication Publication Date Title
DK2364742T3 (da) Indretning til lægemiddelafgivelse
US8617109B2 (en) Device for delivering medicament
US9011386B2 (en) Device for delivering medicament
US7896850B2 (en) Device for delivering medicament
US9205196B2 (en) Medication delivery device
US8475414B2 (en) Medication delivery device and method for operating a medication delivery device
US8226631B2 (en) Drive mechanisms suitable for use in drug delivery devices
EP3858404A1 (en) Injection device
CN112955198A (zh) 扭转弹簧驱动式注射装置
IL170993A (en) Dose dial and drive mechanism suitable for use in drug delivery devices
SG171861A1 (en) Medication delivery device and method for operating a medication delivery device