US3773919A
(en)
*
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
US4289872A
(en)
|
1979-04-06 |
1981-09-15 |
Allied Corporation |
Macromolecular highly branched homogeneous compound based on lysine units
|
ZA811368B
(en)
|
1980-03-24 |
1982-04-28 |
Genentech Inc |
Bacterial polypedtide expression employing tryptophan promoter-operator
|
EP0052322B1
(de)
|
1980-11-10 |
1985-03-27 |
Gersonde, Klaus, Prof. Dr. |
Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
FR2504010B1
(fr)
*
|
1981-04-15 |
1985-10-25 |
Sanofi Sa |
Medicaments anticancereux contenant la chaine a de la ricine associee a un anticorps antimelanome et procede pour leur preparation
|
US4551433A
(en)
|
1981-05-18 |
1985-11-05 |
Genentech, Inc. |
Microbial hybrid promoters
|
JPS57206622A
(en)
*
|
1981-06-10 |
1982-12-18 |
Ajinomoto Co Inc |
Blood substitute
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
NZ201705A
(en)
|
1981-08-31 |
1986-03-14 |
Genentech Inc |
Recombinant dna method for production of hepatitis b surface antigen in yeast
|
US4550096A
(en)
|
1982-01-19 |
1985-10-29 |
Plurichemie Anstalt |
Homogeneous catalytic system comprising rhodium, hydrazine and phosphine and a process for the preparation of same
|
EP0088046B1
(de)
*
|
1982-02-17 |
1987-12-09 |
Ciba-Geigy Ag |
Lipide in wässriger Phase
|
US4671958A
(en)
|
1982-03-09 |
1987-06-09 |
Cytogen Corporation |
Antibody conjugates for the delivery of compounds to target sites
|
DE3377484D1
(en)
*
|
1982-04-19 |
1988-09-01 |
Nissan Motor |
Method for controlling reduction ratio of continuously variable transmission with acceleration compensation
|
DE3218121A1
(de)
|
1982-05-14 |
1983-11-17 |
Leskovar, Peter, Dr.-Ing., 8000 München |
Arzneimittel zur tumorbehandlung
|
EP0102324A3
(de)
|
1982-07-29 |
1984-11-07 |
Ciba-Geigy Ag |
Lipide und Tenside in wässriger Phase
|
US4511502A
(en)
|
1982-12-22 |
1985-04-16 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
US4512922A
(en)
|
1982-12-22 |
1985-04-23 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
US4511503A
(en)
*
|
1982-12-22 |
1985-04-16 |
Genentech, Inc. |
Purification and activity assurance of precipitated heterologous proteins
|
CA1341116C
(en)
|
1983-02-22 |
2000-10-17 |
Rae Lyn Burke |
Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein
|
US5089398A
(en)
*
|
1983-02-22 |
1992-02-18 |
Chiron Corporation |
Enhanced yeast transcription employing hybrid GAPDH promoter region constructs
|
US4876197A
(en)
|
1983-02-22 |
1989-10-24 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
JPS59166086A
(ja)
|
1983-03-09 |
1984-09-19 |
Teruhiko Beppu |
新規な発現型プラスミドとそれらを用いて仔牛プロキモシン遺伝子を大腸菌内で発現させる方法
|
US4755465A
(en)
*
|
1983-04-25 |
1988-07-05 |
Genentech, Inc. |
Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
|
US4859600A
(en)
*
|
1983-04-25 |
1989-08-22 |
Genentech, Inc. |
Recombinant procaryotic cell containing correctly processed human growth hormone
|
EP0127839B1
(en)
|
1983-05-27 |
1992-07-15 |
THE TEXAS A&M UNIVERSITY SYSTEM |
Method for producing a recombinant baculovirus expression vector
|
US4544545A
(en)
*
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
JPS607934A
(ja)
|
1983-06-29 |
1985-01-16 |
Dai Ichi Seiyaku Co Ltd |
リポソ−ムの製造方法
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
US4689406A
(en)
*
|
1983-08-10 |
1987-08-25 |
Amgen |
Enhancement of microbial expression of polypeptides
|
ATE159858T1
(de)
*
|
1983-09-26 |
1997-11-15 |
Ehrenfeld Udo |
Mittel und erzeugnis für die diagnose und therapie von tumoren sowie zur behandlung von schwächen der zelligen und humoralen immunabwehr
|
EP0143949B1
(en)
|
1983-11-01 |
1988-10-12 |
TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION |
Pharmaceutical composition containing urokinase
|
NZ210501A
(en)
|
1983-12-13 |
1991-08-27 |
Kirin Amgen Inc |
Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
|
US4703008A
(en)
|
1983-12-13 |
1987-10-27 |
Kiren-Amgen, Inc. |
DNA sequences encoding erythropoietin
|
KR850004274A
(ko)
|
1983-12-13 |
1985-07-11 |
원본미기재 |
에리트로포이에틴의 제조방법
|
ZA848495B
(en)
|
1984-01-31 |
1985-09-25 |
Idaho Res Found |
Production of polypeptides in insect cells
|
DE3572982D1
(en)
|
1984-03-06 |
1989-10-19 |
Takeda Chemical Industries Ltd |
Chemically modified lymphokine and production thereof
|
US4880734A
(en)
*
|
1984-05-11 |
1989-11-14 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
EP0164566A3
(de)
|
1984-05-11 |
1986-10-29 |
LGA Gastechnik GmbH |
Sicherheitseinrichtung für Flüssiggastanks
|
EP0480480A3
(en)
|
1984-05-11 |
1992-06-10 |
Chiron Corporation |
Enhanced yeast transcription employing hybrid promoter region constructs
|
US4542225A
(en)
|
1984-08-29 |
1985-09-17 |
Dana-Farber Cancer Institute, Inc. |
Acid-cleavable compound
|
US4738921A
(en)
*
|
1984-09-27 |
1988-04-19 |
Eli Lilly And Company |
Derivative of the tryptophan operon for expression of fused gene products
|
US4659839A
(en)
|
1984-10-10 |
1987-04-21 |
Mallinckrodt, Inc. |
Coupling agents for radiolabeled antibody fragments
|
US4837148A
(en)
|
1984-10-30 |
1989-06-06 |
Phillips Petroleum Company |
Autonomous replication sequences for yeast strains of the genus pichia
|
GB8430252D0
(en)
|
1984-11-30 |
1985-01-09 |
Beecham Group Plc |
Compounds
|
ATE66469T1
(de)
|
1985-01-14 |
1991-09-15 |
Neorx Corp |
Metall-radionuklid markiertes protein fuer diagnose und therapie.
|
US4612367A
(en)
|
1985-04-08 |
1986-09-16 |
Eli Lilly And Company |
Process for purifying growth hormone-like materials
|
DE3675588D1
(de)
|
1985-06-19 |
1990-12-20 |
Ajinomoto Kk |
Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
|
US4667016A
(en)
|
1985-06-20 |
1987-05-19 |
Kirin-Amgen, Inc. |
Erythropoietin purification
|
JP2524586B2
(ja)
|
1985-06-26 |
1996-08-14 |
シタス コーポレイション |
ポリマ−接合を利用する医薬組成物用蛋白質の可溶化
|
US4680338A
(en)
*
|
1985-10-17 |
1987-07-14 |
Immunomedics, Inc. |
Bifunctional linker
|
US4818700A
(en)
*
|
1985-10-25 |
1989-04-04 |
Phillips Petroleum Company |
Pichia pastoris argininosuccinate lyase gene and uses thereof
|
US4812405A
(en)
|
1986-02-18 |
1989-03-14 |
Phillips Petroleum Company |
Double auxotrophic mutants of Pichia pastoris and methods for preparation
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
DK173067B1
(da)
*
|
1986-06-27 |
1999-12-13 |
Univ Washington |
Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa
|
JPS63123383A
(ja)
|
1986-11-11 |
1988-05-27 |
Mitsubishi Kasei Corp |
ハイブリツドプロモ−タ−、発現調節dna配列および発現ベクタ−
|
US5186933A
(en)
|
1986-12-30 |
1993-02-16 |
Baylor College Of Medicine |
Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system
|
US4871824A
(en)
|
1987-03-13 |
1989-10-03 |
Minnesota Mining And Manufacturing Company |
Variably crosslinked polymeric supports
|
EP0349594A4
(en)
|
1987-03-16 |
1990-09-26 |
American Biogenetic Sciences, Inc. |
Recombinant baculovirus occlusion bodies in vaccines and biological insecticides
|
EP0284044B1
(en)
|
1987-03-23 |
1994-03-23 |
Zymogenetics, Inc. |
High level expression in yeast
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
WO1989001037A1
(en)
|
1987-07-24 |
1989-02-09 |
Cetus Corporation |
Production of ricin toxins in a baculovirus-insect cell expression system
|
AU2251488A
(en)
|
1987-07-24 |
1989-03-01 |
Cetus Corporation |
Production of biologically active forms of csf using a baculovirus (acnpv)-insect cell expression system
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
US4929555A
(en)
*
|
1987-10-19 |
1990-05-29 |
Phillips Petroleum Company |
Pichia transformation
|
NZ227011A
(en)
|
1987-11-18 |
1992-03-26 |
Chiron Corp |
Non-a, non-b-hepatitis (hepatitis c) antigens, proteins, nucleotide sequences, vaccines and kits
|
US4904584A
(en)
*
|
1987-12-23 |
1990-02-27 |
Genetics Institute, Inc. |
Site-specific homogeneous modification of polypeptides
|
CA1340772C
(en)
|
1987-12-30 |
1999-09-28 |
Patricia Tekamp-Olson |
Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
|
US4847325A
(en)
|
1988-01-20 |
1989-07-11 |
Cetus Corporation |
Conjugation of polymer to colony stimulating factor-1
|
US5674706A
(en)
*
|
1988-05-06 |
1997-10-07 |
Chiron Corporation |
High level expression of proteins in yeast
|
CA1324969C
(en)
|
1988-05-06 |
1993-12-07 |
Jeffrey R. Shuster |
High level expression of proteins in yeast
|
FR2631974B1
(fr)
|
1988-05-31 |
1992-12-11 |
Agronomique Inst Nat Rech |
Baculovirus modifie, son procede de preparation et son application en tant que vecteur d'expression de genes
|
WO1990001556A1
(en)
|
1988-08-05 |
1990-02-22 |
Mount Sinai School Of Medicine Of The City University Of New York |
In vivo infection of live insects with a recombinant baculovirus
|
GB8819453D0
(en)
|
1988-08-16 |
1988-09-21 |
Roy P |
Production of bluetongue virus non-structural proteins using baculovirus expression vector
|
NZ230425A
(en)
|
1988-09-02 |
1992-07-28 |
Molecular Eng Ass |
Production of paramyxovirus fusion (f) protein using recombinant baculovirus expression vector
|
ATE112687T1
(de)
|
1988-09-13 |
1994-10-15 |
Chiron Corp |
Mutanten des hiv-1 hüllproteins mit fehlenden hypervariabelen domänen.
|
GB8824591D0
(en)
|
1988-10-20 |
1988-11-23 |
Royal Free Hosp School Med |
Fractionation process
|
CA2001774C
(en)
|
1988-10-28 |
2001-10-16 |
James A. Wells |
Method for identifying active domains and amino acid residues in polypeptides and hormone variants
|
US6780613B1
(en)
|
1988-10-28 |
2004-08-24 |
Genentech, Inc. |
Growth hormone variants
|
AU649217B2
(en)
|
1988-11-18 |
1994-05-19 |
Regents Of The University Of California, The |
Method for site-specifically incorporating unnatural amino acids into proteins
|
ATE135370T1
(de)
|
1988-12-22 |
1996-03-15 |
Kirin Amgen Inc |
Chemisch modifizierte granulocytenkolonie erregender faktor
|
US4902502A
(en)
*
|
1989-01-23 |
1990-02-20 |
Cetus Corporation |
Preparation of a polymer/interleukin-2 conjugate
|
WO1990008822A1
(en)
|
1989-02-03 |
1990-08-09 |
Genetics Institute, Inc. |
Erythropoietin receptor
|
WO1990010078A1
(en)
|
1989-02-23 |
1990-09-07 |
University Of Ottawa |
Improved baculovirus expression system capable of producing foreign gene proteins at high levels
|
CA2045614C
(en)
|
1989-02-24 |
1997-09-30 |
James W. Bacus |
Method and apparatus for determining a proliferation index of a cell sample
|
ES2247656T3
(es)
|
1989-04-19 |
2006-03-01 |
Enzon, Inc. |
Un proceso para formar un polipeptido modificado que comprende un polipeptido y un oxido de polialquileno.
|
US5324844A
(en)
|
1989-04-19 |
1994-06-28 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
US5122614A
(en)
|
1989-04-19 |
1992-06-16 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
JPH04501065A
(ja)
|
1989-05-17 |
1992-02-27 |
ユニバーシティ オブ ジョージア リサーチ ファウンデーション インコーポレイテッド |
改良されたバキュロウイルス発現ベクター
|
EP0400472B1
(en)
|
1989-05-27 |
1996-04-03 |
Sumitomo Pharmaceuticals Company, Limited |
Process for preparing polyethylene glycol derivatives and modified protein.
|
FR2649120B1
(fr)
|
1989-06-30 |
1994-01-28 |
Cayla |
Nouvelle souche et ses mutants de champignons filamenteux, procede de production de proteines recombinantes a l'aide de ladite souche et souches et proteines obtenues selon ce procede
|
DE3923963A1
(de)
*
|
1989-07-20 |
1991-01-31 |
Behringwerke Ag |
Muteine des menschlichen erythropoetins, ihre herstellung und ihre verwendung
|
DE3924746A1
(de)
|
1989-07-26 |
1991-01-31 |
Behringwerke Ag |
Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper
|
US5856298A
(en)
|
1989-10-13 |
1999-01-05 |
Amgen Inc. |
Erythropoietin isoforms
|
US5312808A
(en)
|
1989-11-22 |
1994-05-17 |
Enzon, Inc. |
Fractionation of polyalkylene oxide-conjugated hemoglobin solutions
|
US5162601A
(en)
*
|
1989-11-22 |
1992-11-10 |
The Upjohn Company |
Plant potyvirus expression vector with a gene for protease
|
US5219564A
(en)
|
1990-07-06 |
1993-06-15 |
Enzon, Inc. |
Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
|
FR2664905B1
(fr)
*
|
1990-07-18 |
1994-08-12 |
Agronomique Inst Nat Rech |
Baculovirus modifie, son procede d'obtention, et vecteurs d'expression obtenus a partir dudit baculovirus.
|
WO1992001800A1
(en)
|
1990-07-20 |
1992-02-06 |
Chiron Corporation |
Method for integrative transformation of yeast using dispersed repetitive elements
|
JPH06501845A
(ja)
|
1990-08-02 |
1994-03-03 |
カイロン コーポレイション |
バキュロウイルス―昆虫細胞発現システムを用いたヒトcmv糖タンパク質―hの発現
|
FR2665923B1
(fr)
|
1990-08-14 |
1993-01-22 |
Arbona Jean |
Unite de soins modulaire.
|
EP0548267A4
(en)
*
|
1990-09-04 |
1994-11-23 |
Salk Inst Biotech Ind |
Production of insulin-like growth factor-1 in methylotrophic yeast cells
|
CA2073511A1
(en)
|
1990-11-14 |
1992-05-29 |
Matthew R. Callstrom |
Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
WO1992009690A2
(en)
*
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with altered binding properties
|
US5292654A
(en)
|
1990-12-13 |
1994-03-08 |
Whitehead Institute For Biomedical Research |
Mutant EPO receptor and uses therefor
|
US5231178A
(en)
*
|
1991-01-16 |
1993-07-27 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Method for the purification of intact, correctly-folded insulin-like growth factor-1
|
JPH06506217A
(ja)
|
1991-03-18 |
1994-07-14 |
エンゾン,インコーポレーテッド |
ポリペプチドまたはグリコポリペプチドとポリマーとのヒドラジン含有結合体
|
WO1992016619A1
(en)
|
1991-03-19 |
1992-10-01 |
Us Army |
Expression of influenza nucleoprotein antigens in baculovirus
|
US5595732A
(en)
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
US6013433A
(en)
|
1991-04-26 |
2000-01-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Baculovirus expression vectors and recombinant antigens for detecting type-specific antibodies to herpes simplex virus
|
DE69231467T2
(de)
*
|
1991-05-10 |
2001-01-25 |
Genentech, Inc. |
Auswählen von agonisten und antagonisten von liganden
|
US5281698A
(en)
*
|
1991-07-23 |
1994-01-25 |
Cetus Oncology Corporation |
Preparation of an activated polymer ester for protein conjugation
|
US5290686A
(en)
*
|
1991-07-31 |
1994-03-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Expression of influenza a M2 protein in baculovirus
|
NZ245015A
(en)
|
1991-11-05 |
1995-12-21 |
Transkaryotic Therapies Inc |
Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
|
JP3210383B2
(ja)
|
1992-01-22 |
2001-09-17 |
株式会社東芝 |
ヘテロ接合バイポーラトランジスタ
|
IT1260468B
(it)
|
1992-01-29 |
1996-04-09 |
|
Metodo per mantenere l'attivita' di enzimi proteolitici modificati con polietilenglicole
|
WO1993021259A1
(en)
|
1992-04-14 |
1993-10-28 |
Cornell Research Foundation Inc. |
Dendritic based macromolecules and method of production
|
US5516657A
(en)
|
1992-05-11 |
1996-05-14 |
Cambridge Biotech Corporation |
Baculovirus vectors for expression of secretory and membrane-bound proteins
|
ZA933926B
(en)
*
|
1992-06-17 |
1994-01-03 |
Amgen Inc |
Polyoxymethylene-oxyethylene copolymers in conjuction with blomolecules
|
US5614184A
(en)
|
1992-07-28 |
1997-03-25 |
New England Deaconess Hospital |
Recombinant human erythropoietin mutants and therapeutic methods employing them
|
US6153407A
(en)
|
1992-07-28 |
2000-11-28 |
Beth Israel Deaconess Medical Center |
Erythropoietin DNA having modified 5' and 3' sequences and its use to prepare EPO therapeutics
|
WO1994004193A1
(en)
|
1992-08-21 |
1994-03-03 |
Enzon, Inc. |
Novel attachment of polyalkylene oxides to bio-effecting substances
|
US5382657A
(en)
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
TW402639B
(en)
|
1992-12-03 |
2000-08-21 |
Transkaryotic Therapies Inc |
Protein production and protein delivery
|
NZ250375A
(en)
|
1992-12-09 |
1995-07-26 |
Ortho Pharma Corp |
Peg hydrazone and peg oxime linkage forming reagents and protein derivatives
|
US5298643A
(en)
|
1992-12-22 |
1994-03-29 |
Enzon, Inc. |
Aryl imidate activated polyalkylene oxides
|
WO1994015625A1
(en)
|
1993-01-15 |
1994-07-21 |
Enzon, Inc. |
Factor viii - polymeric conjugates
|
US5349001A
(en)
|
1993-01-19 |
1994-09-20 |
Enzon, Inc. |
Cyclic imide thione activated polyalkylene oxides
|
US5321095A
(en)
|
1993-02-02 |
1994-06-14 |
Enzon, Inc. |
Azlactone activated polyalkylene oxides
|
US5532142A
(en)
*
|
1993-02-12 |
1996-07-02 |
Board Of Regents, The University Of Texas System |
Method of isolation and purification of fusion polypeptides
|
IL104734A0
(en)
*
|
1993-02-15 |
1993-06-10 |
Univ Bar Ilan |
Bioactive conjugates of cellulose with amino compounds
|
AU6709794A
(en)
*
|
1993-04-21 |
1994-11-08 |
Brigham And Women's Hospital |
Erythropoietin muteins with enhanced activity
|
EP0744953A4
(en)
|
1993-04-29 |
1998-05-06 |
Abbott Lab |
METHODS AND COMPOSITIONS OF ERYTHROPO ETINE ANALOGS
|
WO1994028024A1
(en)
|
1993-06-01 |
1994-12-08 |
Enzon, Inc. |
Carbohydrate-modified polymer conjugates with erythropoietic activity
|
AU7113594A
(en)
|
1993-06-21 |
1995-01-17 |
Enzon, Inc. |
Site specific synthesis of conjugated peptides
|
ZA946122B
(en)
|
1993-08-17 |
1995-03-20 |
Amgen Inc |
Erythropoietin analogs
|
GB9317618D0
(en)
|
1993-08-24 |
1993-10-06 |
Royal Free Hosp School Med |
Polymer modifications
|
US5762939A
(en)
|
1993-09-13 |
1998-06-09 |
Mg-Pmc, Llc |
Method for producing influenza hemagglutinin multivalent vaccines using baculovirus
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
US5491076A
(en)
*
|
1993-11-01 |
1996-02-13 |
The Texas A&M University System |
Expression of foreign genes using a replicating polyprotein producing virus vector
|
US5605792A
(en)
*
|
1993-11-04 |
1997-02-25 |
The Ohio State University Research Foundation |
Infectious bursal disease virus VP2 fusion protein expressed by baculovirus, use as diagnostic
|
AU691225B2
(en)
|
1993-11-10 |
1998-05-14 |
Schering Corporation |
Improved interferon polymer conjugates
|
US5951974A
(en)
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
US5446090A
(en)
*
|
1993-11-12 |
1995-08-29 |
Shearwater Polymers, Inc. |
Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
|
US5773569A
(en)
|
1993-11-19 |
1998-06-30 |
Affymax Technologies N.V. |
Compounds and peptides that bind to the erythropoietin receptor
|
US5830851A
(en)
|
1993-11-19 |
1998-11-03 |
Affymax Technologies N.V. |
Methods of administering peptides that bind to the erythropoietin receptor
|
FR2715664B1
(fr)
|
1994-01-31 |
1996-04-12 |
Proteine Performance Sa |
Baculovirus recombinant et son utilisation pour la production d'anticorps monoclonaux.
|
US6316254B1
(en)
|
1994-02-14 |
2001-11-13 |
University Of Washington |
Methods for stimulating erythropoiesis using hematopoietic proteins
|
US5856179A
(en)
|
1994-03-10 |
1999-01-05 |
Genentech, Inc. |
Polypeptide production in animal cell culture
|
JP3090586B2
(ja)
*
|
1994-03-15 |
2000-09-25 |
片倉工業株式会社 |
システインプロテアーゼ遺伝子欠損バキュロウイルスおよびその製造法並びにこれを利用する有用タンパク質の製造法
|
US5494892A
(en)
|
1994-03-17 |
1996-02-27 |
International Flavors & Fragrances Inc. |
Methyl substituted propyl-substituted pentamethyl indane derivatives processes for producing same and perfumery uses thereof
|
US5473034A
(en)
|
1994-03-18 |
1995-12-05 |
Hyogo Prefectural Government |
Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby
|
US5629384A
(en)
*
|
1994-05-17 |
1997-05-13 |
Consiglio Nazionale Delle Ricerche |
Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces
|
AU2826495A
(en)
|
1994-06-02 |
1996-01-04 |
Enzon, Inc. |
Method of solubilizing substantially water insoluble materials
|
US5730990A
(en)
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
US5572955A
(en)
|
1994-07-08 |
1996-11-12 |
Fambo, Inc. |
Animal amusement and exercising device
|
US6099830A
(en)
|
1994-08-09 |
2000-08-08 |
Zymogenetics, Inc. |
Methods for stimulating erythropoiesis using hematopoietic proteins
|
US6403375B1
(en)
|
1994-08-24 |
2002-06-11 |
Boyce Thompson Institute For Plant Research, Inc. |
Establishment of Trichoplusia ni cell lines in serum-free medium for recombinant protein and baculovirus production
|
US5650234A
(en)
|
1994-09-09 |
1997-07-22 |
Surface Engineering Technologies, Division Of Innerdyne, Inc. |
Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces
|
US5871986A
(en)
|
1994-09-23 |
1999-02-16 |
The General Hospital Corporation |
Use of a baculovirus to express and exogenous gene in a mammalian cell
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
EP0788375A2
(en)
|
1994-11-09 |
1997-08-13 |
Robin Ewart Offord |
Functionalized polymers for site-specific attachment
|
US5738846A
(en)
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
US5932462A
(en)
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
AU4724996A
(en)
|
1995-02-16 |
1996-09-04 |
Medical Research Council |
Sperm factor
|
AU720337B2
(en)
|
1995-02-17 |
2000-05-25 |
Stichting Dienst Landbouwkundig Onderzoek |
Production of biologically active recombinant bovine follicle stimulating hormone (REC bFSH) in the baculovirus expression system
|
FR2732035B1
(fr)
|
1995-03-23 |
1997-05-30 |
Agronomique Inst Nat Rech |
Procede de regulation de l'expression d'un gene dans un baculovirus, par un site de fixation d'un recepteur de l'acide retinoique, et vecteur pour la mise en oeuvre du dit procede
|
IL118201A
(en)
|
1995-05-11 |
2004-12-15 |
Roche Diagnostics Gmbh |
Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
|
NZ308772A
(en)
|
1995-05-17 |
1999-04-29 |
Du Pont |
Recombinant baculovirus insecticides
|
AU5893696A
(en)
|
1995-06-07 |
1996-12-30 |
Novo Nordisk A/S |
Modification of polypeptides
|
EP0886648B8
(en)
*
|
1995-06-07 |
2004-03-03 |
Ortho Pharmaceutical Corporation |
Compounds and peptides that bind to the erythropoietin receptor
|
US5767078A
(en)
*
|
1995-06-07 |
1998-06-16 |
Johnson; Dana L. |
Agonist peptide dimers
|
US5672662A
(en)
|
1995-07-07 |
1997-09-30 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
|
US5955349A
(en)
|
1996-08-26 |
1999-09-21 |
Zymogenetics, Inc. |
Compositions and methods for producing heterologous polypeptides in Pichia methanolica
|
US5703283A
(en)
|
1995-11-24 |
1997-12-30 |
Motorola Inc. |
Detrending engine positional data for rotating position encoders
|
WO1997026332A1
(en)
|
1996-01-17 |
1997-07-24 |
Schering Corporation |
Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin 5 antagonists
|
US5861279A
(en)
|
1996-01-17 |
1999-01-19 |
Schering Corporation |
Baculovirus expression system for human interleukin 5 receptor and method of screening for interleukin 5 antagonists
|
US5747639A
(en)
|
1996-03-06 |
1998-05-05 |
Amgen Boulder Inc. |
Use of hydrophobic interaction chromatography to purify polyethylene glycols
|
TW517067B
(en)
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
TW586933B
(en)
|
1996-06-20 |
2004-05-11 |
Chugai Pharmaceutical Co Ltd |
Compositions for treating liver-complaints using EPO
|
US5736383A
(en)
|
1996-08-26 |
1998-04-07 |
Zymogenetics, Inc. |
Preparation of Pichia methanolica auxotrophic mutants
|
DK0964702T3
(da)
|
1996-08-02 |
2007-01-08 |
Ortho Mcneil Pharm Inc |
Polypeptider med en enkelt kovalent bundet N-terminal vandoplöselig polymer
|
US5980948A
(en)
|
1996-08-16 |
1999-11-09 |
Osteotech, Inc. |
Polyetherester copolymers as drug delivery matrices
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US5998595A
(en)
|
1996-11-05 |
1999-12-07 |
Wako Pure Chemical Industries, Ltd. |
Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups
|
EP0946736B1
(en)
|
1996-12-13 |
2003-10-29 |
Chiron Corporation |
Method for expression of heterologous proteins in yeast
|
GB9701237D0
(en)
|
1997-01-22 |
1997-03-12 |
Nycomed Imaging As |
Improvements in or relating to contrast agents
|
US6221608B1
(en)
|
1997-01-22 |
2001-04-24 |
Ortho Pharmaceutical Corporation |
Methods for identifying erythropoietin receptor binding protein
|
ATE200030T1
(de)
|
1997-01-29 |
2001-04-15 |
Polymasc Pharmaceuticals Plc |
Pegylationsverfahren
|
GB9703406D0
(en)
*
|
1997-02-19 |
1997-04-09 |
Chiron Spa |
Expression of heterologous proteins
|
US6440526B1
(en)
|
1997-03-26 |
2002-08-27 |
Craig Steven John Gamble |
Non-slip pad
|
US6323322B1
(en)
|
1997-04-30 |
2001-11-27 |
Enzon, Inc. |
Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof
|
US5990237A
(en)
|
1997-05-21 |
1999-11-23 |
Shearwater Polymers, Inc. |
Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
|
RO121474B1
(ro)
|
1997-06-06 |
2007-06-29 |
Kyowa Hakko Kogyo Co., Ltd. |
Polipeptide modificate chimic
|
US5965393A
(en)
|
1997-07-01 |
1999-10-12 |
National Institute Of Immunology |
Method for enhancing foreign gene expression in baculovirus expression vector system
|
US6187564B1
(en)
|
1997-07-10 |
2001-02-13 |
Beth Israel Deaconess Medical Center |
DNA encoding erythropoietin multimers having modified 5′ and 3′ sequences and its use to prepare EPO therapeutics
|
WO1999003887A1
(en)
|
1997-07-14 |
1999-01-28 |
Bolder Biotechnology, Inc. |
Derivatives of growth hormone and related proteins
|
PT986644E
(pt)
|
1997-07-23 |
2007-01-31 |
Roche Diagnostics Gmbh |
Preparação de eritropoietina por activação genética endógena com promotores virais
|
CN1151258C
(zh)
|
1997-07-23 |
2004-05-26 |
罗切诊断学有限公司 |
通过内源基因活化制备***
|
GB9715660D0
(en)
|
1997-07-25 |
1997-10-01 |
Zeneca Ltd |
Proteins
|
AU8688798A
(en)
|
1997-08-05 |
1999-03-01 |
Chiron Corporation |
Novel (pichia pastoris) gene sequences and methods for their use
|
DE19735593C2
(de)
|
1997-08-15 |
1999-08-26 |
Hepavec Ag Fuer Gentherapie |
Hüllprotein-modifizierter Baculovirus-Vektor für die Gentherapie
|
US6090584A
(en)
|
1997-08-21 |
2000-07-18 |
University Technologies International Inc. |
Baculovirus artificial chromosomes and methods of use
|
DK0902085T3
(da)
|
1997-09-01 |
2004-04-05 |
Aventis Pharma Gmbh |
Rekombinant human erythropoietin med fordelagtig glycosyleringsprofil
|
US5989868A
(en)
|
1997-09-12 |
1999-11-23 |
The Board Of Regents Of The University Of Oklahoma |
Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in esherichia coli
|
DE69841578D1
(de)
|
1997-09-16 |
2010-05-06 |
Centocor Inc |
Methoden zur kompletten chemischen Synthese und Zusammensetzung von Genen und Genomen
|
CA2320156A1
(en)
|
1997-09-26 |
1999-04-08 |
Uab Research Foundation |
Reduced antigenic cells and uses therefor
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
US6201072B1
(en)
|
1997-10-03 |
2001-03-13 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
US6165783A
(en)
|
1997-10-24 |
2000-12-26 |
Neuro Spheres Holdings Ltd. |
Erythropoietin-mediated neurogenesis
|
DE19748489A1
(de)
|
1997-11-03 |
1999-05-06 |
Roche Diagnostics Gmbh |
Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
|
US6448369B1
(en)
|
1997-11-06 |
2002-09-10 |
Shearwater Corporation |
Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation
|
EP0924298A1
(en)
|
1997-12-18 |
1999-06-23 |
Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) |
Protein expression in baculovirus vector expression systems
|
US5985263A
(en)
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
US5981709A
(en)
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
TW445295B
(en)
|
1997-12-31 |
2001-07-11 |
Shiu Li Wei |
Expression vector pcDNA3.1-HC for human erythropoietin, BHK-21 host cell line transformed therewith, and production of human erythropoietin using the transformed cell
|
DE19803557C2
(de)
|
1998-01-30 |
1999-12-23 |
Koenig & Bauer Ag |
Antrieb für ein rotierendes Bauteil einer Druckmaschine
|
US6274158B1
(en)
|
1998-02-04 |
2001-08-14 |
Veronica L. Zaharia Czeizler |
Treatment with recombinant human erythropoietin of bleeding in patients with normal and abnormal hemostasis
|
CA2319701C
(en)
|
1998-02-09 |
2009-09-29 |
University Of Southern California |
Method of promoting erythropoiesis
|
JP2002505110A
(ja)
|
1998-03-04 |
2002-02-19 |
オニックス ファーマシューティカルズ,インコーポレイティド |
遺伝物質の高生産性発現のためのバキュロウイルス発現系及び方法
|
WO1999045026A1
(en)
|
1998-03-05 |
1999-09-10 |
Chiron Corporation |
Method for increasing the serum half-life of a biologically active molecule
|
DK1411075T3
(da)
|
1998-03-12 |
2008-10-27 |
Nektar Therapeutics Al Corp |
Fremgangsmåde til fremstilling af polymerkonjugater
|
KR100264953B1
(ko)
|
1998-04-03 |
2001-03-02 |
박현우 |
재조합 베큘로바이러스, 이의 제조방법 및 이를 포함하는 미생물 살충제
|
IL124015A0
(en)
|
1998-04-08 |
1999-01-26 |
Yeda Res & Dev |
Pharmaceutical compositions comprising a protein
|
AR019025A1
(es)
|
1998-04-09 |
2001-12-26 |
Roche Diagnostics Gmbh |
Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado
|
US6310078B1
(en)
*
|
1998-04-20 |
2001-10-30 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituted amino acids as erythropoietin mimetics
|
DE69933216T2
(de)
|
1998-06-15 |
2007-09-20 |
GTC Biotherapeutics, Inc., Framingham |
Erythropoietin-analog-menschliches serum-albumin fusionsprotein
|
US6451986B1
(en)
|
1998-06-22 |
2002-09-17 |
Immunex Corporation |
Site specific protein modification
|
US6168932B1
(en)
|
1998-07-13 |
2001-01-02 |
Parker Hughes Institute |
Recombinant DTctGMCSF fusion toxin in a baculovirus expression vector system
|
US6171821B1
(en)
|
1998-07-24 |
2001-01-09 |
Apoptogen, Inc. |
XIAP IRES and uses thereof
|
US6245528B1
(en)
|
1998-07-28 |
2001-06-12 |
Academia Sinica |
Latent baculovirus expression system
|
US6368825B1
(en)
|
1998-08-10 |
2002-04-09 |
Academia Sinica |
Baculovirus containing minimal CMV promoter
|
ATE364654T1
(de)
|
1998-08-28 |
2007-07-15 |
Amylin Pharmaceuticals Inc |
Polyamideketten von genauer länge und deren konjugate mit proteinen
|
WO2000020032A1
(en)
|
1998-10-06 |
2000-04-13 |
Trustees Of Dartmouth College |
RECOMBINANT CAT ALLERGEN, Fel dI, EXPRESSED IN BACULOVIRUS FOR DIAGNOSIS AND TREATMENT OF CAT ALLERGY
|
US6420339B1
(en)
|
1998-10-14 |
2002-07-16 |
Amgen Inc. |
Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
|
US6165283A
(en)
|
1998-10-23 |
2000-12-26 |
Dahlin; William G. |
Railcar cleaning method and apparatus
|
CA2348822A1
(en)
|
1998-10-30 |
2000-05-11 |
Novozymes A/S |
Glycosylated proteins having reduced allergenicity
|
AU2346900A
(en)
|
1998-11-30 |
2000-06-19 |
Eli Lilly And Company |
Erythropoietic compounds
|
US6451346B1
(en)
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
JP4805432B2
(ja)
|
1998-12-28 |
2011-11-02 |
ランクセス・ドイチュランド・ゲーエムベーハー |
木質材又は木質複合材を製造する際に使用される接着剤混入用薬剤
|
US6281211B1
(en)
|
1999-02-04 |
2001-08-28 |
Euro-Celtique S.A. |
Substituted semicarbazides and the use thereof
|
EP1177311B1
(en)
|
1999-03-17 |
2014-11-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
In vitro macromolecule biosynthesis methods using exogenous amino acids and a novel atp regeneration system
|
US6994986B2
(en)
|
1999-03-17 |
2006-02-07 |
The Board Of Trustees Of The Leland Stanford University |
In vitro synthesis of polypeptides by optimizing amino acid metabolism
|
US6342216B1
(en)
|
1999-03-17 |
2002-01-29 |
The Board Of Regents, The University Of Texas System |
Therapy of cancer by insect cells containing recombinant baculovirus encoding genes
|
US6642353B1
(en)
|
1999-03-17 |
2003-11-04 |
Chugai Seiyaku Kabushiki Kaisha |
Peptide ligands for the erythropoietin receptor
|
US6337191B1
(en)
|
1999-03-22 |
2002-01-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Vitro protein synthesis using glycolytic intermediates as an energy source
|
US6258559B1
(en)
|
1999-03-22 |
2001-07-10 |
Zymogenetics, Inc. |
Method for producing proteins in transformed Pichia
|
HUP0201068A3
(en)
|
1999-04-09 |
2002-10-28 |
Ortho Mcneil Pharm Inc |
Pharmaceutical compositions of erythropoietin
|
CA2370330C
(en)
|
1999-04-16 |
2009-01-20 |
Wm. Marsh Rice University |
Biodegradable poly(propylene fumarate) networks cross linked with poly(propylene fumarate)-diacrylate macromers
|
CN1367701A
(zh)
|
1999-05-11 |
2002-09-04 |
奥索-麦克尼尔药物公司 |
红细胞生成素给药的药代动力学和药效模型
|
CZ299516B6
(cs)
|
1999-07-02 |
2008-08-20 |
F. Hoffmann-La Roche Ag |
Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
|
PE20010288A1
(es)
|
1999-07-02 |
2001-03-07 |
Hoffmann La Roche |
Derivados de eritropoyetina
|
US6261805B1
(en)
|
1999-07-15 |
2001-07-17 |
Boyce Thompson Institute For Plant Research, Inc. |
Sialyiation of N-linked glycoproteins in the baculovirus expression vector system
|
US6485937B1
(en)
|
1999-10-15 |
2002-11-26 |
The Rockefeller University |
System for rapid generation of recombinant baculovirus-based expression vectors for silkworm larvae
|
US6703480B1
(en)
|
1999-11-24 |
2004-03-09 |
Palani Balu |
Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use
|
US6348558B1
(en)
|
1999-12-10 |
2002-02-19 |
Shearwater Corporation |
Hydrolytically degradable polymers and hydrogels made therefrom
|
AU781729B2
(en)
|
1999-12-22 |
2005-06-09 |
Nektar Therapeutics |
Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
|
WO2001046291A1
(en)
|
1999-12-22 |
2001-06-28 |
Shearwater Corporation |
Sterically hindered derivatives of water soluble polymers
|
US6413507B1
(en)
|
1999-12-23 |
2002-07-02 |
Shearwater Corporation |
Hydrolytically degradable carbamate derivatives of poly (ethylene glycol)
|
US6646110B2
(en)
|
2000-01-10 |
2003-11-11 |
Maxygen Holdings Ltd. |
G-CSF polypeptides and conjugates
|
AU2001238595A1
(en)
|
2000-02-22 |
2001-09-03 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
AU2001257577A1
(en)
|
2000-02-28 |
2001-09-03 |
Shearwater Corporation |
Water-soluble polymer conjugates of artelinic acid
|
US6586398B1
(en)
|
2000-04-07 |
2003-07-01 |
Amgen, Inc. |
Chemically modified novel erythropoietin stimulating protein compositions and methods
|
US6586207B2
(en)
|
2000-05-26 |
2003-07-01 |
California Institute Of Technology |
Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues
|
GB0012997D0
(en)
|
2000-05-26 |
2000-07-19 |
Eurogene Limited |
Gene delivery
|
JP2002030098A
(ja)
|
2000-07-17 |
2002-01-29 |
Institute Of Immunology Co Ltd |
バキュロウィルスの発芽ウイルスからウイルスエンベロープを回収する方法
|
US7118737B2
(en)
*
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
US6436386B1
(en)
|
2000-11-14 |
2002-08-20 |
Shearwater Corporation |
Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
|
TW593427B
(en)
|
2000-12-18 |
2004-06-21 |
Nektar Therapeutics Al Corp |
Synthesis of high molecular weight non-peptidic polymer derivatives
|
US20030072737A1
(en)
|
2000-12-29 |
2003-04-17 |
Michael Brines |
Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
|
US6531121B2
(en)
|
2000-12-29 |
2003-03-11 |
The Kenneth S. Warren Institute, Inc. |
Protection and enhancement of erythropoietin-responsive cells, tissues and organs
|
PA8536201A1
(es)
|
2000-12-29 |
2002-08-29 |
Kenneth S Warren Inst Inc |
Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina
|
TWI246524B
(en)
|
2001-01-19 |
2006-01-01 |
Shearwater Corp |
Multi-arm block copolymers as drug delivery vehicles
|
AU2002303431C1
(en)
|
2001-04-19 |
2008-03-06 |
The Regents Of The University Of California |
Methods and composition for the production of orthoganal tRNA-aminoacyltRNA synthetase pairs
|
JP2003104050A
(ja)
|
2001-09-27 |
2003-04-09 |
Nippon Pop Rivets & Fasteners Ltd |
モール取付装置及びモールクリップ
|
US6908963B2
(en)
|
2001-10-09 |
2005-06-21 |
Nektar Therapeutics Al, Corporation |
Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
|
MXPA04004336A
(es)
|
2001-11-07 |
2005-05-16 |
Nektar Therapeutics Al Corp |
Polimeros ramificados y sus conjugados.
|
KR101271635B1
(ko)
*
|
2001-12-21 |
2013-06-12 |
휴먼 게놈 사이언시즈, 인코포레이티드 |
알부민 융합 단백질
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
EP1329860B1
(en)
|
2002-01-11 |
2006-11-08 |
Hochiki Corporation |
Flame detection device
|
EP2226316B1
(en)
|
2002-05-30 |
2016-01-13 |
The Scripps Research Institute |
Copper-catalysed ligation of azides and acetylenes
|
US20040122216A1
(en)
|
2002-07-01 |
2004-06-24 |
Jacob Nielsen |
Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
|
DK1578949T3
(da)
|
2002-10-16 |
2009-07-27 |
Scripps Research Inst |
Stedspecifik optagelse af keto-aminnosyrer hos proteiner
|
ES2333422T3
(es)
|
2002-10-16 |
2010-02-22 |
The Scripps Research Institute |
Sintesis de glicoproteinas.
|
EP1583816A4
(en)
|
2002-12-22 |
2007-06-13 |
Scripps Research Inst |
PROTEIN NETWORKS
|
JP2006511225A
(ja)
|
2002-12-23 |
2006-04-06 |
アジレント・テクノロジーズ・インク |
固定化オリゴヌクレオチドフィーチャーを用いた比較ゲノムハイブリダイゼーションアッセイ及びその実施に用いるための組成物
|
CN100522988C
(zh)
*
|
2003-04-09 |
2009-08-05 |
诺和诺德公司 |
糖peg化方法及由该方法生产的蛋白质/肽
|
US7618775B2
(en)
|
2003-04-17 |
2009-11-17 |
The Scripps Research Institute |
Expanding the eukaryotic genetic code
|
EP1666604B1
(en)
|
2003-07-07 |
2008-02-13 |
The Scripps Research Institute |
Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
|
EP1658366A4
(en)
|
2003-07-07 |
2006-08-09 |
Scripps Research Inst |
COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES
|
EP1704242A4
(en)
|
2003-07-07 |
2008-06-18 |
Scripps Research Inst |
COMPOSITIONS WITH PAIRS OF ORTHOGONAL LEUCYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF
|
SG176455A1
(en)
|
2003-10-09 |
2011-12-29 |
Ambrx Inc |
Polymer derivatives
|
CN103755800B
(zh)
|
2004-02-02 |
2016-02-24 |
Ambrx公司 |
经修饰的人类生长激素多肽与其用途
|
ZA200606216B
(en)
*
|
2004-02-02 |
2007-11-28 |
Ambrx Inc |
Modified human interferon polypeptides and their uses
|
EP1781697B1
(en)
|
2004-07-07 |
2009-04-22 |
H.Lundbeck A/S |
Novel carbamylated epo and method for its production
|
CN103690936A
(zh)
*
|
2004-12-22 |
2014-04-02 |
Ambrx公司 |
经修饰的人类生长激素
|
EP1853913A2
(en)
*
|
2005-02-24 |
2007-11-14 |
Amgen Inc. |
Detection of compounds that affect therapeutic activity
|
WO2007026772A1
(ja)
*
|
2005-08-31 |
2007-03-08 |
Kaneka Corporation |
ネコ由来タンパク質のコード配列を含む外来性遺伝子を含むトランスジェニック鳥類およびその作製法
|
EP2120998B1
(en)
*
|
2006-11-28 |
2013-08-07 |
HanAll Biopharma Co., Ltd. |
Modified erythropoietin polypeptides and uses thereof for treatment
|
AR065613A1
(es)
|
2007-03-09 |
2009-06-17 |
Chugai Pharmaceutical Co Ltd |
Agentes de proteccion para organos transplantados
|
EP2318029B1
(en)
|
2008-07-23 |
2017-11-01 |
Ambrx, Inc. |
Modified bovine g-csf polypeptides and their uses
|
KR101647164B1
(ko)
*
|
2008-09-26 |
2016-08-09 |
암브룩스, 인코포레이티드 |
변형된 동물 에리트로포이에틴 폴리펩티드 및 이의 용도
|