DK2336125T3 - Thiazolopyridin-2-yloxy-phenyl- og thioazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-A4-hydrolase - Google Patents
Thiazolopyridin-2-yloxy-phenyl- og thioazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-A4-hydrolaseInfo
- Publication number
- DK2336125T3 DK2336125T3 DK11159236.6T DK11159236T DK2336125T3 DK 2336125 T3 DK2336125 T3 DK 2336125T3 DK 11159236 T DK11159236 T DK 11159236T DK 2336125 T3 DK2336125 T3 DK 2336125T3
- Authority
- DK
- Denmark
- Prior art keywords
- yloxy
- thioazolopyrazin
- thiazolopyridin
- phenylamines
- leukotriene
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
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-
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4434908P | 2008-04-11 | 2008-04-11 | |
US14912909P | 2009-02-02 | 2009-02-02 | |
EP09729596.8A EP2268646B9 (en) | 2008-04-11 | 2009-04-09 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2336125T3 true DK2336125T3 (da) | 2013-04-08 |
Family
ID=41130551
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11159236.6T DK2336125T3 (da) | 2008-04-11 | 2009-04-09 | Thiazolopyridin-2-yloxy-phenyl- og thioazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-A4-hydrolase |
DK09729596.8T DK2268646T3 (da) | 2008-04-11 | 2009-04-09 | Thiazolopyridin-2-yloxy-phenyl og thiazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-a4-hydrolase |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09729596.8T DK2268646T3 (da) | 2008-04-11 | 2009-04-09 | Thiazolopyridin-2-yloxy-phenyl og thiazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-a4-hydrolase |
Country Status (36)
Country | Link |
---|---|
US (3) | US7939527B2 (da) |
EP (2) | EP2268646B9 (da) |
JP (2) | JP5530423B2 (da) |
KR (1) | KR101228378B1 (da) |
CN (1) | CN102056933B (da) |
AR (1) | AR072353A1 (da) |
AU (1) | AU2009234140B2 (da) |
BR (1) | BRPI0911336A2 (da) |
CA (1) | CA2721099C (da) |
CL (1) | CL2009000877A1 (da) |
CO (1) | CO6260069A2 (da) |
CY (1) | CY1114628T1 (da) |
DK (2) | DK2336125T3 (da) |
EA (1) | EA018802B1 (da) |
EC (1) | ECSP10010558A (da) |
ES (2) | ES2440746T3 (da) |
HK (2) | HK1152041A1 (da) |
HN (1) | HN2010002074A (da) |
HR (2) | HRP20130278T1 (da) |
IL (2) | IL208480A (da) |
JO (1) | JO2911B1 (da) |
MX (1) | MX2010011154A (da) |
MY (1) | MY157597A (da) |
NI (1) | NI201000168A (da) |
NZ (2) | NZ588341A (da) |
PE (1) | PE20091779A1 (da) |
PH (1) | PH12013500094A1 (da) |
PL (2) | PL2268646T3 (da) |
PT (2) | PT2268646E (da) |
RS (2) | RS52712B (da) |
SI (2) | SI2336125T1 (da) |
SV (1) | SV2010003694A (da) |
TW (2) | TW201420100A (da) |
UY (1) | UY31760A (da) |
WO (1) | WO2009126806A2 (da) |
ZA (1) | ZA201008054B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101228378B1 (ko) * | 2008-04-11 | 2013-01-31 | 얀센 파마슈티카 엔.브이. | 류코트리엔 α4 하이드롤레이즈의 조정제로서의 티아졸로피리딘-2-일옥시-페닐 및 티아졸로피라진-2-일옥시-페닐 아민 |
CA2866471A1 (en) | 2012-03-06 | 2013-09-12 | Boehringer Ingelheim International Gmbh | Benzodioxanes in combination with other actives for inhibiting leukotriene production |
TW201350474A (zh) * | 2012-03-06 | 2013-12-16 | Boehringer Ingelheim Int | 白三烯素生成之苯并二噁烷抑制劑 |
JP6256467B2 (ja) | 2012-07-17 | 2018-01-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成を阻害するピラゾール誘導体 |
EP2746260A1 (en) | 2012-12-21 | 2014-06-25 | Basf Se | Substituted [1,2,4]triazole and imidazole compounds |
EP2746259A1 (en) | 2012-12-21 | 2014-06-25 | Basf Se | Substituted [1,2,4]triazole and imidazole compounds |
JP6527851B2 (ja) | 2013-03-12 | 2019-06-05 | セルタクシス,インコーポレイテッド | ロイコトリエンa4加水分解酵素を阻害する方法 |
KR20150127245A (ko) | 2013-03-14 | 2015-11-16 | 켈탁시스, 인코퍼레이티드 | 류코트라이엔 a4 가수분해효소의 저해제 |
BR112015022227A2 (pt) * | 2013-03-14 | 2017-07-18 | Celtaxsys Inc | inibidores de leucotrieno a4 hidrolase |
JP7386815B2 (ja) | 2018-05-31 | 2023-11-27 | セルタクシー、エルエルシー | 呼吸器疾患患者の肺増悪を軽減する方法 |
AU2020206036A1 (en) | 2019-01-11 | 2021-08-05 | Naegis Pharmaceuticals Inc. | Leukotriene synthesis inhibitors |
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