DK2331210T3 - Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og et antiepileptika - Google Patents

Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og et antiepileptika

Info

Publication number: DK2331210T3
Authority: DK; Denmark
Prior art keywords: dimethylamino; phenol; propyl; ethyl; methyl
Prior art date: 2008-09-05

Application number

DK09778335.1T

Other languages

English (en)

Inventor

Petra Bloms-Funke

Klaus Schiene

Thomas Christoph

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-09-05

Filing date

2009-09-04

Publication date

2014-08-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40345058&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2331210(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-09-04 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2014-08-11 Application granted granted Critical

2014-08-11 Publication of DK2331210T3 publication Critical patent/DK2331210T3/da

Links

KWTWDQCKEHXFFR-UHFFFAOYSA-N 3-[1-(dimethylamino)-2-methylpentan-3-yl]phenol Chemical compound CN(C)CC(C)C(CC)C1=CC=CC(O)=C1 KWTWDQCKEHXFFR-UHFFFAOYSA-N 0.000 title 1
239000001961 anticonvulsive agent Substances 0.000 title 1
229960003965 antiepileptics Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

DK09778335.1T 2008-09-05 2009-09-04 Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og et antiepileptika DK2331210T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08015625		2008-09-05
PCT/EP2009/006424 WO2010025931A2 (en)	2008-09-05	2009-09-04	Pharmaceutical combination

Publications (1)

Publication Number	Publication Date
DK2331210T3 true DK2331210T3 (da)	2014-08-11

Family

ID=40345058

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK09778335.1T DK2331210T3 (da)	2008-09-05	2009-09-04	Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og et antiepileptika
DK14000597.6T DK2735338T3 (da)	2008-09-05	2009-09-04	Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og pregabalin eller gabapentin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK14000597.6T DK2735338T3 (da)	2008-09-05	2009-09-04	Farmaceutisk kombination af 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol og pregabalin eller gabapentin

Country Status (29)

Country	Link
US (1)	US20100063148A1 (da)
EP (2)	EP2735338B1 (da)
JP (4)	JP5731387B2 (da)
KR (3)	KR101641519B1 (da)
CN (2)	CN105520924B (da)
AR (2)	AR073361A1 (da)
AU (3)	AU2009289776A1 (da)
BR (1)	BRPI0920521A2 (da)
CA (1)	CA2735857C (da)
CL (1)	CL2011000317A1 (da)
CO (1)	CO6382142A2 (da)
CY (2)	CY1115751T1 (da)
DK (2)	DK2331210T3 (da)
EC (1)	ECSP11010869A (da)
ES (2)	ES2513394T3 (da)
HK (2)	HK1198145A1 (da)
HR (2)	HRP20140663T1 (da)
HU (1)	HUE043278T2 (da)
IL (3)	IL211135A (da)
LT (1)	LT2735338T (da)
MX (1)	MX2011002339A (da)
PE (5)	PE20190914A1 (da)
PL (2)	PL2735338T3 (da)
PT (2)	PT2331210E (da)
RU (2)	RU2571501C2 (da)
SI (2)	SI2735338T1 (da)
TR (1)	TR201904388T4 (da)
WO (1)	WO2010025931A2 (da)
ZA (1)	ZA201101449B (da)

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US7612112B2 (en)	2001-10-25	2009-11-03	Depomed, Inc.	Methods of treatment using a gastric retained gabapentin dosage
US20090176882A1 (en)	2008-12-09	2009-07-09	Depomed, Inc.	Gastric retentive gabapentin dosage forms and methods for using same
EA027836B1 (ru)	2006-06-15	2017-09-29	ЮСиБи ФАРМА ГМБХ	Фармацевтическая комбинация для профилактики, облегчения и/или лечения приступов эпилепсии и ее применение
US20100190752A1 (en)	2008-09-05	2010-07-29	Gruenenthal Gmbh	Pharmaceutical Combination
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MX2012014482A (es)	2010-06-15	2013-02-21	Gruenenthal Gmbh	Combinacion farmaceutica.
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US20130310385A1 (en)	2012-05-18	2013-11-21	Gruenenthal Gmbh	Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9308196B2 (en) *	2012-05-18	2016-04-12	Gruenenthal Gmbh	Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
US9345689B2 (en) *	2012-05-18	2016-05-24	Gruenenthal Gmbh	Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US9855286B2 (en) *	2012-05-18	2018-01-02	Gruenenthal Gmbh	Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US9320729B2 (en)	2012-05-18	2016-04-26	Gruenenthal Gmbh	Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US9320725B2 (en)	2012-05-18	2016-04-26	Gruenenthal Gmbh	Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
US8912226B2 (en) *	2012-05-18	2014-12-16	Gruenenthal Gmbh	Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
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2009
- 2009-09-04 PE PE2018003303A patent/PE20190914A1/es unknown
- 2009-09-04 MX MX2011002339A patent/MX2011002339A/es active IP Right Grant
- 2009-09-04 EP EP14000597.6A patent/EP2735338B1/en active Active
- 2009-09-04 KR KR1020117005044A patent/KR101641519B1/ko active Application Filing
- 2009-09-04 LT LTEP14000597.6T patent/LT2735338T/lt unknown
- 2009-09-04 PE PE2014001115A patent/PE20142357A1/es active IP Right Grant
- 2009-09-04 DK DK09778335.1T patent/DK2331210T3/da active
- 2009-09-04 PE PE2011000206A patent/PE20110291A1/es active IP Right Grant
- 2009-09-04 JP JP2011525465A patent/JP5731387B2/ja active Active
- 2009-09-04 AR ARP090103405A patent/AR073361A1/es not_active Application Discontinuation
- 2009-09-04 KR KR1020177010825A patent/KR101851120B1/ko active IP Right Grant
- 2009-09-04 AU AU2009289776A patent/AU2009289776A1/en not_active Abandoned
- 2009-09-04 RU RU2011112444/15A patent/RU2571501C2/ru active
- 2009-09-04 PT PT97783351T patent/PT2331210E/pt unknown
- 2009-09-04 BR BRPI0920521A patent/BRPI0920521A2/pt not_active Application Discontinuation
- 2009-09-04 EP EP09778335.1A patent/EP2331210B1/en active Active
- 2009-09-04 TR TR2019/04388T patent/TR201904388T4/tr unknown
- 2009-09-04 SI SI200931945T patent/SI2735338T1/sl unknown
- 2009-09-04 PE PE2014001117A patent/PE20142372A1/es active IP Right Grant
- 2009-09-04 CN CN201510736012.5A patent/CN105520924B/zh not_active Expired - Fee Related
- 2009-09-04 ES ES09778335.1T patent/ES2513394T3/es active Active
- 2009-09-04 HU HUE14000597A patent/HUE043278T2/hu unknown
- 2009-09-04 CN CN200980135117.8A patent/CN102159284B/zh not_active Expired - Fee Related
- 2009-09-04 KR KR1020167018592A patent/KR101730924B1/ko active IP Right Grant
- 2009-09-04 RU RU2014138166A patent/RU2674150C1/ru active
- 2009-09-04 PT PT14000597T patent/PT2735338T/pt unknown
- 2009-09-04 WO PCT/EP2009/006424 patent/WO2010025931A2/en active Application Filing
- 2009-09-04 SI SI200931014T patent/SI2331210T1/sl unknown
- 2009-09-04 PE PE2014001116A patent/PE20142371A1/es active IP Right Grant
- 2009-09-04 PL PL14000597T patent/PL2735338T3/pl unknown
- 2009-09-04 CA CA2735857A patent/CA2735857C/en not_active Expired - Fee Related
- 2009-09-04 US US12/554,235 patent/US20100063148A1/en not_active Abandoned
- 2009-09-04 DK DK14000597.6T patent/DK2735338T3/da active
- 2009-09-04 PL PL09778335T patent/PL2331210T3/pl unknown
- 2009-09-04 ES ES14000597T patent/ES2719900T3/es active Active
2011
- 2011-02-09 IL IL211135A patent/IL211135A/en active IP Right Grant
- 2011-02-14 CL CL2011000317A patent/CL2011000317A1/es unknown
- 2011-02-16 CO CO11018461A patent/CO6382142A2/es active IP Right Grant
- 2011-02-23 ZA ZA2011/01449A patent/ZA201101449B/en unknown
- 2011-03-04 EC EC2011010869A patent/ECSP11010869A/es unknown
- 2011-12-13 HK HK14111224.9A patent/HK1198145A1/xx not_active IP Right Cessation
- 2011-12-13 HK HK11113438.0A patent/HK1159011A1/xx not_active IP Right Cessation
2014
- 2014-07-14 HR HRP20140663AT patent/HRP20140663T1/hr unknown
- 2014-09-16 CY CY20141100748T patent/CY1115751T1/el unknown
- 2014-12-12 JP JP2014251851A patent/JP2015096530A/ja active Pending
2015
- 2015-02-24 IL IL237392A patent/IL237392B/en active IP Right Grant
- 2015-02-24 IL IL237391A patent/IL237391A/en active IP Right Grant
2016
- 2016-05-11 AU AU2016203053A patent/AU2016203053B2/en not_active Ceased
- 2016-12-12 JP JP2016240032A patent/JP2017071636A/ja active Pending
2018
- 2018-04-26 AU AU2018202879A patent/AU2018202879B2/en not_active Ceased
2019
- 2019-03-13 HR HRP20190500TT patent/HRP20190500T1/hr unknown
- 2019-03-27 CY CY20191100357T patent/CY1121492T1/el unknown
- 2019-04-02 JP JP2019070282A patent/JP2019131578A/ja active Pending
- 2019-07-19 AR ARP190102034A patent/AR117613A2/es unknown

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Publication number	Publication date
PL2331210T3 (pl)	2014-12-31
PL2735338T3 (pl)	2019-07-31
PE20190914A1 (es)	2019-06-26
HK1198145A1 (en)	2015-03-13
EP2331210A2 (en)	2011-06-15
IL237391A0 (en)	2015-04-30
KR101641519B1 (ko)	2016-07-21
RU2011112444A (ru)	2012-10-10
PE20142371A1 (es)	2015-02-04
AR117613A2 (es)	2021-08-18
CA2735857C (en)	2019-05-28
IL237392B (en)	2019-08-29
JP2015096530A (ja)	2015-05-21
KR20170048602A (ko)	2017-05-08
SI2735338T1 (sl)	2019-04-30
AU2016203053A1 (en)	2016-06-02
HRP20190500T1 (hr)	2019-08-09
IL211135A (en)	2017-09-28
JP2019131578A (ja)	2019-08-08
CN102159284B (zh)	2015-12-09
IL237391A (en)	2017-12-31
EP2331210B1 (en)	2014-07-09
PE20142372A1 (es)	2015-02-04
PE20142357A1 (es)	2015-02-04
MX2011002339A (es)	2011-04-04
BRPI0920521A2 (pt)	2018-01-16
AU2016203053B2 (en)	2018-01-25
HRP20140663T1 (hr)	2014-10-10
JP5731387B2 (ja)	2015-06-10
CY1115751T1 (el)	2017-01-25
CN105520924B (zh)	2019-04-09
AU2018202879B2 (en)	2020-03-12
IL237392A0 (en)	2015-04-30
DK2735338T3 (da)	2019-04-23
EP2735338A1 (en)	2014-05-28
HK1159011A1 (en)	2012-07-27
SI2331210T1 (sl)	2014-10-30
CO6382142A2 (es)	2012-02-15
PT2331210E (pt)	2014-08-25
HUE043278T2 (hu)	2019-08-28
JP2012501986A (ja)	2012-01-26
CY1121492T1 (el)	2020-05-29
KR101730924B1 (ko)	2017-04-27
ES2719900T3 (es)	2019-07-16
WO2010025931A3 (en)	2010-06-17
RU2571501C2 (ru)	2015-12-20
JP2017071636A (ja)	2017-04-13
TR201904388T4 (tr)	2019-05-21
EP2735338B1 (en)	2019-02-06
RU2674150C1 (ru)	2018-12-05
PT2735338T (pt)	2019-05-24
KR101851120B1 (ko)	2018-04-23
LT2735338T (lt)	2019-04-10
ZA201101449B (en)	2011-10-26
CN105520924A (zh)	2016-04-27
AU2009289776A1 (en)	2010-03-11
CN102159284A (zh)	2011-08-17
CL2011000317A1 (es)	2011-06-17
AU2018202879A1 (en)	2018-05-17
IL211135A0 (en)	2011-04-28
WO2010025931A2 (en)	2010-03-11
CA2735857A1 (en)	2010-03-11
KR20160086981A (ko)	2016-07-20
AR073361A1 (es)	2010-11-03
ES2513394T3 (es)	2014-10-27
KR20110057144A (ko)	2011-05-31
US20100063148A1 (en)	2010-03-11
PE20110291A1 (es)	2011-06-04
ECSP11010869A (es)	2011-04-29

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