DK2242743T3 - Aminopyrazolderivater - Google Patents
AminopyrazolderivaterInfo
- Publication number
- DK2242743T3 DK2242743T3 DK08862120.6T DK08862120T DK2242743T3 DK 2242743 T3 DK2242743 T3 DK 2242743T3 DK 08862120 T DK08862120 T DK 08862120T DK 2242743 T3 DK2242743 T3 DK 2242743T3
- Authority
- DK
- Denmark
- Prior art keywords
- aminopyrazole
- Prior art date
Links
- JVVRJMXHNUAPHW-UHFFFAOYSA-N 1h-pyrazol-5-amine Chemical compound NC=1C=CNN=1 JVVRJMXHNUAPHW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2007055111 | 2007-12-14 | ||
IB2008053648 | 2008-09-10 | ||
PCT/IB2008/055251 WO2009077954A1 (en) | 2007-12-14 | 2008-12-12 | Aminopyrazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2242743T3 true DK2242743T3 (da) | 2013-10-14 |
Family
ID=40456559
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08862120.6T DK2242743T3 (da) | 2007-12-14 | 2008-12-12 | Aminopyrazolderivater |
Country Status (25)
Country | Link |
---|---|
US (1) | US8288419B2 (da) |
EP (1) | EP2242743B1 (da) |
JP (1) | JP5435744B2 (da) |
KR (1) | KR101622413B1 (da) |
CN (1) | CN101903353B (da) |
AR (1) | AR069650A1 (da) |
BR (1) | BRPI0821004A8 (da) |
CA (1) | CA2706836C (da) |
CY (1) | CY1114793T1 (da) |
DK (1) | DK2242743T3 (da) |
ES (1) | ES2432059T3 (da) |
HK (1) | HK1148286A1 (da) |
HR (1) | HRP20131105T1 (da) |
IL (1) | IL206296A (da) |
MA (1) | MA31988B1 (da) |
MX (1) | MX2010005827A (da) |
MY (1) | MY153921A (da) |
NZ (1) | NZ586776A (da) |
PL (1) | PL2242743T3 (da) |
PT (1) | PT2242743E (da) |
RU (1) | RU2489426C2 (da) |
SI (1) | SI2242743T1 (da) |
TW (1) | TWI430795B (da) |
WO (1) | WO2009077954A1 (da) |
ZA (1) | ZA201004939B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2225231E (pt) | 2007-12-18 | 2011-10-19 | Actelion Pharmaceuticals Ltd | Derivados de aminotriazolcomo agonistas de alx |
NZ597122A (en) | 2009-05-18 | 2013-06-28 | Actelion Pharmaceuticals Ltd | Bridged spiro [2.4] heptane derivatives as alx receptor and/or fprl2 agonists |
US8580831B2 (en) | 2009-06-09 | 2013-11-12 | Actelion Pharmaceuticals Ltd. | Fluorinated aminotriazole derivatives |
JP5624130B2 (ja) * | 2009-06-12 | 2014-11-12 | アクテリオンファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | Alx受容体アゴニストとしてのオキサゾール及びチアゾール誘導体 |
MA34234B1 (fr) | 2010-04-07 | 2013-05-02 | Hoffmann La Roche | Composes pyrazol-4-yl-heterocyclyle-carboxamide et leurs procedes d'utilisation |
KR101905927B1 (ko) | 2010-11-17 | 2018-10-08 | 이도르시아 파마슈티컬스 리미티드 | 가교된 스피로[2.4]헵탄 에스테르 유도체 |
CA2816406C (en) | 2010-12-07 | 2019-02-26 | Actelion Pharmaceuticals Ltd | Hydroxylated aminotriazole derivatives as alx receptor agonists |
PL2649068T3 (pl) * | 2010-12-07 | 2015-03-31 | Idorsia Pharmaceuticals Ltd | Pochodne eteru oksazolilowo-metylowego jako agoniści receptora ALX |
ES2541531T3 (es) | 2011-02-18 | 2015-07-21 | Actelion Pharmaceuticals Ltd. | Nuevos derivados de pirazol e imidazol útiles como antagonistas de orexina |
EP2707373A1 (de) | 2011-05-10 | 2014-03-19 | Bayer Intellectual Property GmbH | Bicyclische (thio)carbonylamidine |
RU2638552C2 (ru) | 2011-09-27 | 2017-12-14 | Ф. Хоффманн-Ля Рош Аг | Пиразол-4-ил-гетероциклил-карбоксамидные соединения и способы применения |
DE102011055815A1 (de) | 2011-11-29 | 2013-05-29 | Aicuris Gmbh & Co. Kg | Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung |
MA37618B1 (fr) | 2012-05-16 | 2017-08-31 | Actelion Pharmaceuticals Ltd | Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx |
CA2871334A1 (en) | 2012-05-16 | 2013-11-21 | Actelion Pharmaceuticals Ltd | 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists |
DE102012016908A1 (de) | 2012-08-17 | 2014-02-20 | Aicuris Gmbh & Co. Kg | Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung |
AR096686A1 (es) | 2013-06-25 | 2016-01-27 | Actelion Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx |
AU2014292064B2 (en) | 2013-07-18 | 2018-07-05 | Idorsia Pharmaceuticals Ltd | Piperazine substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists |
AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
LT3075726T (lt) | 2013-11-28 | 2018-03-26 | Kyorin Pharmaceutical Co., Ltd. | Karbamido dariniai arba farmakologiniu požiūriu priimtinos jų druskos, naudotini kaip formilpeptido receptoriaus tipo 1 (fprl-1) agonistai |
CN107848962B (zh) | 2015-05-27 | 2021-04-09 | 杏林制药株式会社 | 脲衍生物或其药理学上可接受的盐 |
MX2017015040A (es) | 2015-05-27 | 2018-08-14 | Kyorin Seiyaku Kk | Derivado de urea o sal farmacologicamente aceptable del mismo. |
CN111868052B (zh) | 2018-03-05 | 2024-03-08 | 百时美施贵宝公司 | 苯基吡咯烷酮甲酰肽2受体激动剂 |
US10829485B2 (en) * | 2018-04-06 | 2020-11-10 | Black Belt Tx Ltd | ATF6 inhibitors and uses thereof |
WO2023118434A1 (en) * | 2021-12-22 | 2023-06-29 | Globachem Nv | Pesticidally active amide compounds |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8531019D0 (en) * | 1985-12-17 | 1986-01-29 | Beecham Group Plc | Compounds |
JPS62234018A (ja) | 1986-04-02 | 1987-10-14 | Rooto Seiyaku Kk | 糖尿病併発症治療剤 |
ATE278674T1 (de) * | 1999-03-12 | 2004-10-15 | Boehringer Ingelheim Pharma | Heterocyklischer harnstoff und verwandte verbindungen als entzündungshemmende mittel |
AU2001290258A1 (en) * | 2000-09-22 | 2002-04-02 | Nihon Nohyaku Co. Ltd. | N-(4-pyrazolyl)amide derivatives, chemicals for agricultural and horticultural use, and usage of the same |
CN1280289C (zh) * | 2001-03-02 | 2006-10-18 | 弗·哈夫曼-拉罗切有限公司 | 用作ip拮抗剂的烷氧基羰基氨基杂芳基羧酸衍生物 |
JP2005536187A (ja) | 2002-04-03 | 2005-12-02 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | N−ホルミルペプチド受容体様1(fprl1)に関連する疾患の診断および治療 |
US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
JP2007516434A (ja) * | 2003-11-07 | 2007-06-21 | アカディア ファーマシューティカルズ インコーポレイティド | リポキシン受容体fprl1の、疼痛および炎症の治療に有効な化合物を識別する手段としての使用 |
GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
CA2626897A1 (en) | 2005-11-03 | 2007-05-18 | Joshua Close | Histone deacetylase inhibitors with aryl-pyrazolyl motifs |
GB0606876D0 (en) * | 2006-04-05 | 2006-05-17 | Glaxo Group Ltd | Compounds |
EP2487169B1 (en) | 2007-08-21 | 2015-05-20 | Senomyx, Inc. | Compounds that inhibit (block) bitter taste in compositions and use thereof |
PT2225231E (pt) | 2007-12-18 | 2011-10-19 | Actelion Pharmaceuticals Ltd | Derivados de aminotriazolcomo agonistas de alx |
NZ597122A (en) | 2009-05-18 | 2013-06-28 | Actelion Pharmaceuticals Ltd | Bridged spiro [2.4] heptane derivatives as alx receptor and/or fprl2 agonists |
US8580831B2 (en) | 2009-06-09 | 2013-11-12 | Actelion Pharmaceuticals Ltd. | Fluorinated aminotriazole derivatives |
JP5624130B2 (ja) | 2009-06-12 | 2014-11-12 | アクテリオンファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | Alx受容体アゴニストとしてのオキサゾール及びチアゾール誘導体 |
-
2008
- 2008-12-11 AR ARP080105380A patent/AR069650A1/es unknown
- 2008-12-12 BR BRPI0821004A patent/BRPI0821004A8/pt not_active IP Right Cessation
- 2008-12-12 TW TW097148594A patent/TWI430795B/zh not_active IP Right Cessation
- 2008-12-12 DK DK08862120.6T patent/DK2242743T3/da active
- 2008-12-12 US US12/808,137 patent/US8288419B2/en not_active Expired - Fee Related
- 2008-12-12 PL PL08862120T patent/PL2242743T3/pl unknown
- 2008-12-12 MY MYPI2010002723A patent/MY153921A/en unknown
- 2008-12-12 NZ NZ586776A patent/NZ586776A/en not_active IP Right Cessation
- 2008-12-12 MX MX2010005827A patent/MX2010005827A/es active IP Right Grant
- 2008-12-12 CA CA2706836A patent/CA2706836C/en not_active Expired - Fee Related
- 2008-12-12 KR KR1020107015524A patent/KR101622413B1/ko not_active IP Right Cessation
- 2008-12-12 ES ES08862120T patent/ES2432059T3/es active Active
- 2008-12-12 PT PT88621206T patent/PT2242743E/pt unknown
- 2008-12-12 EP EP08862120.6A patent/EP2242743B1/en not_active Not-in-force
- 2008-12-12 JP JP2010537589A patent/JP5435744B2/ja not_active Expired - Fee Related
- 2008-12-12 WO PCT/IB2008/055251 patent/WO2009077954A1/en active Application Filing
- 2008-12-12 RU RU2010128240/04A patent/RU2489426C2/ru not_active IP Right Cessation
- 2008-12-12 CN CN2008801219752A patent/CN101903353B/zh not_active Expired - Fee Related
- 2008-12-12 SI SI200831072T patent/SI2242743T1/sl unknown
-
2010
- 2010-06-10 IL IL206296A patent/IL206296A/en not_active IP Right Cessation
- 2010-06-29 MA MA32967A patent/MA31988B1/fr unknown
- 2010-07-13 ZA ZA2010/04939A patent/ZA201004939B/en unknown
-
2011
- 2011-03-11 HK HK11102486.4A patent/HK1148286A1/xx not_active IP Right Cessation
-
2013
- 2013-11-20 CY CY20131101025T patent/CY1114793T1/el unknown
- 2013-11-20 HR HRP20131105AT patent/HRP20131105T1/hr unknown
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