DK220484A - Enteralt kontrastmiddel til kernespintomografi og dets fremstilling - Google Patents

Enteralt kontrastmiddel til kernespintomografi og dets fremstilling Download PDF

Info

Publication number
DK220484A
DK220484A DK220484A DK220484A DK220484A DK 220484 A DK220484 A DK 220484A DK 220484 A DK220484 A DK 220484A DK 220484 A DK220484 A DK 220484A DK 220484 A DK220484 A DK 220484A
Authority
DK
Denmark
Prior art keywords
physiologically compatible
spintomography
nuclear
preparation
contrast agent
Prior art date
Application number
DK220484A
Other languages
English (en)
Other versions
DK166528B1 (da
DK220484D0 (da
Inventor
Hanns-Joachim Weinmann
Heinz Gries
Heinrich Michel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK220484D0 publication Critical patent/DK220484D0/da
Publication of DK220484A publication Critical patent/DK220484A/da
Application granted granted Critical
Publication of DK166528B1 publication Critical patent/DK166528B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK220484A 1983-05-04 1984-05-03 Enteralt kontrastmiddel til kernespintomografi og dets fremstilling DK166528B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833316703 DE3316703A1 (de) 1983-05-04 1983-05-04 Orales kontrastmittel fuer die kernspintomographie und dessen herstellung
DE3316703 1983-05-04

Publications (3)

Publication Number Publication Date
DK220484D0 DK220484D0 (da) 1984-05-03
DK220484A true DK220484A (da) 1984-11-05
DK166528B1 DK166528B1 (da) 1993-06-07

Family

ID=6198394

Family Applications (1)

Application Number Title Priority Date Filing Date
DK220484A DK166528B1 (da) 1983-05-04 1984-05-03 Enteralt kontrastmiddel til kernespintomografi og dets fremstilling

Country Status (9)

Country Link
US (1) US4719098A (da)
EP (1) EP0124766B1 (da)
JP (1) JPS6016936A (da)
AT (1) ATE45287T1 (da)
CA (1) CA1244346A (da)
DE (2) DE3316703A1 (da)
DK (1) DK166528B1 (da)
FI (1) FI80831C (da)
NO (1) NO160824C (da)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330801A1 (en) * 1983-02-08 1989-09-06 Schering Aktiengesellschaft Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease
US4735796A (en) * 1983-12-08 1988-04-05 Gordon Robert T Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease
US5401491A (en) * 1984-05-31 1995-03-28 Guerbet S.A. NMR contrast agents
PT81498B (pt) * 1984-11-23 1987-12-30 Schering Ag Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas
US5746999A (en) * 1984-11-23 1998-05-05 Schering Aktiengesellschaft Magnetic particles for diagnostic purposes
DE3614142C2 (de) * 1985-04-26 1996-03-28 Toshiba Kawasaki Kk Verwendung eines Materials für die Diagnose durch Kernresonanz-Spektroskopie
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US5336762A (en) * 1985-11-18 1994-08-09 Access Pharmaceuticals, Inc. Polychelating agents for image and spectral enhancement (and spectral shift)
EP0247156B1 (en) * 1985-11-18 1993-06-23 Access Pharmaceuticals Inc. Polychelating agents for image and spectral enhancement (and spectral shift)
MX174467B (es) * 1986-01-23 1994-05-17 Squibb & Sons Inc 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos
EP0232751B1 (en) * 1986-01-23 1991-09-11 E.R. Squibb & Sons, Inc. 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5248492A (en) * 1986-07-03 1993-09-28 Advanced Magnetics, Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
US5102652A (en) * 1986-07-03 1992-04-07 Advanced Magnetics Inc. Low molecular weight carbohydrates as additives to stabilize metal oxide compositions
US4827945A (en) * 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate
US5567411A (en) * 1986-11-10 1996-10-22 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Dendritic amplifier molecules having multiple terminal active groups stemming from a benzyl core group
US5252317A (en) * 1986-11-10 1993-10-12 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Amplifier molecules for diagnosis and therapy derived from 3,5-bis[1-(3-amino-2,2-bis (aminomethyl)-propyl) oxymethyl] benzoic acid
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
IT1224416B (it) * 1987-12-24 1990-10-04 Bracco Ind Chimica Spa Chelanti macrociclici e loro chelati
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
DE3710730A1 (de) * 1987-03-31 1988-10-20 Schering Ag Substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
FR2614020B1 (fr) * 1987-04-14 1989-07-28 Guerbet Sa Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands.
US5154179A (en) * 1987-07-02 1992-10-13 Medical Magnetics, Inc. Device construction and method facilitating magnetic resonance imaging of foreign objects in a body
US4927624A (en) * 1987-11-19 1990-05-22 The University Of Rochester Clay magnetic resonance contrast agents for gastrointestinal comsumption or introduction
GB8813144D0 (en) * 1988-06-03 1988-07-06 Nycomed As Compositions
JPH0678247B2 (ja) * 1988-10-04 1994-10-05 大塚製薬株式会社 Nmr造影用鉄含有製剤
US5702683A (en) * 1989-01-24 1997-12-30 The United States Of America As Represented By The United States Department Of Energy Nuclear magnetic resonance contrast agents
JPH0810375B2 (ja) * 1989-04-12 1996-01-31 キヤノン株式会社 定着装置
GB8916782D0 (en) * 1989-07-21 1989-09-06 Nycomed As Compositions
US5393525A (en) * 1989-07-21 1995-02-28 Nycomed Imaging As Contrast medium comprising superparamagnetic or ferromagnetic particles capable of increasing viscosity after administration
GB8916781D0 (en) * 1989-07-21 1989-09-06 Nycomed As Compositions
GB8916780D0 (en) * 1989-07-21 1989-09-06 Nycomed As Compositions
KR0149014B1 (ko) * 1989-09-27 1998-10-15 오쓰카세이야쿠가부시키가이샤 Nmr 조영용 철 함유 제제
US5120527A (en) * 1989-10-19 1992-06-09 King Chuen Peter Li Paramagnetic oil emulsions as mri contrast agents
US5064636A (en) * 1989-10-19 1991-11-12 Li King C P Paramagnetic oil emulsions as enteric MRI contrast agents
US5368840A (en) * 1990-04-10 1994-11-29 Imarx Pharmaceutical Corp. Natural polymers as contrast media for magnetic resonance imaging
ES2138122T3 (es) * 1990-04-10 2000-01-01 Imarx Pharmaceutical Corp Polimeros como medios de contraste para resonancia magnetica.
US5268165A (en) * 1990-10-16 1993-12-07 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
US5885549A (en) * 1991-02-01 1999-03-23 Imarx Pharmaceutical Corp. Phosphorylated materials as contrast agents for use in magnetic resonance imaging of the gastrointestinal region
US5143716A (en) * 1991-02-01 1992-09-01 Unger Evan C Phosphorylated sugar alcohols, Mono- and Di-Saccharides as contrast agents for use in magnetic resonance imaging of the gastrointestinal region
US5240693A (en) * 1991-05-01 1993-08-31 University Of New Mexico Image enhancement by coadministration of biomodulators and structurally modified imaging agents
EP0673655A1 (en) * 1992-03-19 1995-09-27 Daikin Industries, Limited Mri contrast medium and diagnostic method
JPH06157355A (ja) * 1992-11-13 1994-06-03 Dai Ichi Seiyaku Co Ltd Mri用粒状製剤
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
US5861140A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Tripodal paramagnetic contrast agents for MR imaging
US5861138A (en) * 1996-11-20 1999-01-19 Hoechst Celanese Corp. Ligands for MRI contrast agent
US5820851A (en) * 1997-08-21 1998-10-13 Hoechst Celanese Corporation Tripodal pyridine ligands as MRI contrast agents
US5858329A (en) * 1997-08-21 1999-01-12 Hoechst Celanese Corporation MRI diagnostic procedures using tripodal pyridinyl metal complexes
US5869026A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corp. Tripodal carboxamide ligands for MRI contrast agents
US5824288A (en) * 1997-08-21 1998-10-20 Hoechst Celanese Corporation Thio-substituted pyridines as MRI ligand precursors
US5869025A (en) * 1997-08-21 1999-02-09 Hoechst Celanese Corporation Tripodal aromatic heterocycle carboxamide MRI contrast agents
US5980863A (en) * 1998-11-02 1999-11-09 Eagle Vision Pharmaceutical Corporation Manganese compositions and methods for MRI
AR036354A1 (es) * 2001-08-31 2004-09-01 Takeda Chemical Industries Ltd Preparacion solida
EP1458328B1 (en) * 2001-11-21 2013-01-30 Bracco Diagnostics Inc. Formulations comprising locust bean gum as stabilizing agent and mannitol as osmotic agent for use in medical or diagnostic procedures

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832457A (en) * 1969-06-20 1974-08-27 Rikagaku Kenkyusho Ferrite contrast media with metallic oxides
FR2210391B1 (da) * 1972-12-19 1976-07-02 Heitz Fernand
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
US4615879A (en) * 1983-11-14 1986-10-07 Vanderbilt University Particulate NMR contrast agents for gastrointestinal application

Also Published As

Publication number Publication date
NO841773L (no) 1984-11-05
JPS6016936A (ja) 1985-01-28
NO160824B (no) 1989-02-27
JPH0477734B2 (da) 1992-12-09
EP0124766A2 (de) 1984-11-14
FI841788A (fi) 1984-11-05
DE3316703A1 (de) 1984-11-08
NO160824C (no) 1989-06-07
CA1244346A (en) 1988-11-08
FI80831B (fi) 1990-04-30
DE3479291D1 (en) 1989-09-14
FI80831C (fi) 1990-08-10
ATE45287T1 (de) 1989-08-15
FI841788A0 (fi) 1984-05-04
US4719098A (en) 1988-01-12
DK166528B1 (da) 1993-06-07
EP0124766A3 (en) 1986-12-30
DK220484D0 (da) 1984-05-03
EP0124766B1 (de) 1989-08-09

Similar Documents

Publication Publication Date Title
DK220484A (da) Enteralt kontrastmiddel til kernespintomografi og dets fremstilling
DE3872741D1 (de) Magnetische fluessigkeitszusammensetzungen.
FI956312A0 (fi) Proteiinikoteloidut liukenemattoman kaasun mikropallot ja niiden valmistus sekä käyttö ultraäänikuvauksen apuaineina
FI920238A0 (fi) Varjoaineita
ATE35827T1 (de) Menschliches lymphotoxin und seine derivate, verfahren zu seiner herstellung und dasselbe enthaltende pharmazeutische zusammensetzungen.
ATE99544T1 (de) Liposomale radiologische kontrastmittel.
IL73958A0 (en) Contrast agents and method of use thereof
FR2297034A1 (fr) Composition pour la localisation d'isotopes radioactifs en medecine
ES2024601B3 (es) Proceso para marcar sustancias con tecnicio o renio.
ATE133339T1 (de) Mittel zur magnetischen resonanzabbildung
FI905419A0 (fi) Icke-joniska roentgenkontrastmedel med hoeg jodhalt.
KR930700163A (ko) 연조직 종양의 치료 및/또는 진단 방법
ES2036033T3 (es) Composiciones y metodos para lograr una respuesta fisiologica mejorada al ejercicio.
IE781195L (en) Diagnostic kit for blood pool imaging
Lüllmann et al. The distribution of 3H‐labelled cardenolides between isolated guinea‐pig atrial tissue and circulating, oxygenated whole blood
JPS567725A (en) Tumor scanning agent
Sjaastad et al. Rupture of the imidazole ring of histamine and N‐acetylhistamine by human intestinal contents
JPS5251031A (en) Diagostic reagents containing 3'-deoxy-3-iodoglucoe
GB1391843A (en) X-ray contrast agents
IT1054620B (it) Poli(idrossimetilene)idroinsolubile biologicamente attivo procedimento per la sua preparazione e suo impiego nella cromatografia per affinita
SU585829A1 (ru) Устройство дл выбирани рыбы из воды
Zullo et al. Occurrence of Oecetis inconspicua(Walker) in an Acid Strip-Mine Lake of Southern Illinois
JPS56166124A (en) Diagnostic injection for malignant tumor
Ferguson et al. Diagnostic Possibilities for 99mTc Abdominal Scanning
Collins et al. False-Positive Thromboscintigram Resulting From Lymphedema—A Roentgen Pathological Model

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired