DK2073636T3 - Fremgangsmåde til fremstilling af oxymorphon - Google Patents

Fremgangsmåde til fremstilling af oxymorphon

Info

Publication number
DK2073636T3
DK2073636T3 DK07840163.5T DK07840163T DK2073636T3 DK 2073636 T3 DK2073636 T3 DK 2073636T3 DK 07840163 T DK07840163 T DK 07840163T DK 2073636 T3 DK2073636 T3 DK 2073636T3
Authority
DK
Denmark
Prior art keywords
oxymorphone
procedure
manufacturing
manufacturing oxymorphone
Prior art date
Application number
DK07840163.5T
Other languages
English (en)
Inventor
Bao-Shan Huang
Original Assignee
Penick Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39314340&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2073636(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Penick Corp filed Critical Penick Corp
Application granted granted Critical
Publication of DK2073636T3 publication Critical patent/DK2073636T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
DK07840163.5T 2006-10-17 2007-05-02 Fremgangsmåde til fremstilling af oxymorphon DK2073636T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82981706P 2006-10-17 2006-10-17
US61104906A 2006-12-14 2006-12-14
PCT/US2007/068009 WO2008048711A1 (en) 2006-10-17 2007-05-02 Process for preparing oxymorphone

Publications (1)

Publication Number Publication Date
DK2073636T3 true DK2073636T3 (da) 2012-11-19

Family

ID=39314340

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07840163.5T DK2073636T3 (da) 2006-10-17 2007-05-02 Fremgangsmåde til fremstilling af oxymorphon

Country Status (6)

Country Link
US (1) US8134002B2 (da)
EP (1) EP2073636B1 (da)
AU (1) AU2007313103C1 (da)
DK (1) DK2073636T3 (da)
ES (1) ES2392594T3 (da)
WO (1) WO2008048711A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1994034B1 (en) * 2006-03-02 2009-11-11 Mallinckrodt, Inc. Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds
CA2674915C (en) 2006-10-17 2015-06-30 Penick Corporation Process for preparing oxymorphone
US20080125592A1 (en) * 2006-10-17 2008-05-29 Penick Corporation Process for preparing oxymorphone, naltrexone, and buprenorphine
US8217175B2 (en) 2007-03-23 2012-07-10 Mallinckrodt Llc Preparation of oxymorphone from oripavine
WO2008130553A1 (en) 2007-04-16 2008-10-30 Mallinckrodt Inc. Novel opiate reduction utilizing catalytic hydrogen transfer reaction
EP2377866B1 (en) * 2010-03-23 2014-02-26 Siegfried AG Preparation of low impurity opiates in a continuous flow reactor
AU2011263417B2 (en) 2010-06-11 2014-03-27 Rhodes Technologies Transition metal-catalyzed processes for the preparation of N-allyl compounds and use thereof
EP2580218B1 (en) 2010-06-11 2015-02-25 Rhodes Technologies Process for n-dealkylation of tertiary amines
CA2804940C (en) 2010-07-08 2017-03-07 Alkermes Pharma Ireland Limited Process for the synthesis of substituted morphinans
US8563571B2 (en) 2010-07-22 2013-10-22 Noramco, Inc. Crystalline forms of oxymorphone hydrochloride
SI2608670T1 (sl) 2010-08-23 2019-04-30 Alkermes Pharma Ireland Limited Postopki za zdravljenje pridobivanja teže, ki je posledica uporabe antipsihotičnih zdravil
US8946214B2 (en) 2011-05-06 2015-02-03 Brock University Process for the preparation of morphine analogs via metal catalyzed N-demethylation/functionalization and intramolecular group transfer
CA2837233A1 (en) 2011-05-27 2012-12-06 Grunenthal Gmbh Crystalline, anhydrous forms of oxymorphone hydrochloride
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9657029B2 (en) 2012-06-11 2017-05-23 Siegfried Generics International Ag Method of preparing oxymorphone
GB2517000B (en) 2013-08-02 2018-05-09 Johnson Matthey Plc Process for the synthesis of oxymorphone alkaloid and oxymorphone salts
US9918979B2 (en) * 2015-01-29 2018-03-20 Johnson Matthey Public Limited Company Process of preparing low ABUK oxymorphone hydrochloride
US9757372B2 (en) * 2015-03-25 2017-09-12 Taiwanj Pharmaceuticals Co., Ltd. Toll-like receptor 4 antagonists and use in autoimmune liver diseases
EP3252055B1 (en) 2016-05-31 2018-09-19 Alcaliber Investigacion Desarrollo e Innovacion SLU Process for obtaining 3,14-diacetyloxymorphone from oripavine
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474101A (en) 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US3332950A (en) 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
GB1317210A (en) 1970-12-11 1973-05-16 Macarlan Smith Ltd Reduction of thebaine
FR2636330B1 (fr) 1988-09-13 1990-11-30 Sanofi Sa Procede de preparation de derives de morphinane
PT95069B (pt) 1989-08-24 1997-10-31 Searle & Co Processo para a preparacao de (+)-isomeros de derivados de endoetano/endoetanoepoximofinano, uteis como agentes anti-tussicos
EP0912577A2 (en) 1996-05-21 1999-05-06 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Novel methods of o-demethylation and n-deprotection
US6067749A (en) 1996-07-11 2000-05-30 Tasmanian Alkaloids Pty. Ltd. Papaver somniferum strain with high concentration of thebaine and oripavine
US5869669A (en) 1996-07-26 1999-02-09 Penick Corporation Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates
US6187782B1 (en) 1997-03-27 2001-02-13 Toray Industries, Inc. Morphinane derivatives and medicinal use thereof
GB9713703D0 (en) 1997-06-30 1997-09-03 Johnson Matthey Plc Preparation of opiates
US6177567B1 (en) 1999-10-15 2001-01-23 Boehringer Ingelheim Chemicals, Inc. Method for preparing oxycodone
US6864370B1 (en) 2003-06-05 2005-03-08 Zhaiwei Lin Process for manufacturing oxycodone
HUE034668T2 (hu) 2003-09-22 2018-02-28 Glaxosmithkline Australia Pty Ltd Eljárás morfinán-származékok szintézisére és azok intermedierjei
US7875718B2 (en) 2003-09-22 2011-01-25 Johnson Matthey Public Limited Company Process for the synthesis of morphinane compounds and intermediates thereof
TWI365880B (en) 2004-03-30 2012-06-11 Euro Celtique Sa Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and oxycodone hydrochloride composition,pharmaceutical dosage form,sustained release oeal dosage form and pharmaceutically acceptable package having less than 25 pp
WO2006005112A1 (en) 2004-07-09 2006-01-19 Tasmanian Alkaloids Pty Ltd Process for the synthesis of hydromorphone
GB0421149D0 (en) 2004-09-23 2004-10-27 Johnson Matthey Plc Preparation of oxycodone
WO2006084389A1 (de) 2005-02-11 2006-08-17 Cilag Ltd. Verfahren zur reinigung von noroxymorphon-verbindungen
EP1994034B1 (en) 2006-03-02 2009-11-11 Mallinckrodt, Inc. Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds
US20080125592A1 (en) 2006-10-17 2008-05-29 Penick Corporation Process for preparing oxymorphone, naltrexone, and buprenorphine
CA2674915C (en) 2006-10-17 2015-06-30 Penick Corporation Process for preparing oxymorphone
GB0624880D0 (en) 2006-12-14 2007-01-24 Johnson Matthey Plc Improved method for making analgesics
CA2738758C (en) 2008-09-30 2016-11-29 Mallinckrodt Inc. Processes for the alkylation of norbuprenorphine with reduced impurity formation

Also Published As

Publication number Publication date
WO2008048711A1 (en) 2008-04-24
ES2392594T3 (es) 2012-12-12
AU2007313103A1 (en) 2008-04-24
AU2007313103B2 (en) 2012-09-13
EP2073636A4 (en) 2009-10-28
AU2007313103C1 (en) 2014-01-30
EP2073636A1 (en) 2009-07-01
US20110009634A1 (en) 2011-01-13
US8134002B2 (en) 2012-03-13
EP2073636B1 (en) 2012-09-05

Similar Documents

Publication Publication Date Title
DK2073636T3 (da) Fremgangsmåde til fremstilling af oxymorphon
LTC2004635I2 (lt) Pakeistieji enaminokarbonilo junginiai
DK2035166T3 (da) Fremgangsmåde til fremstilling af beholdere
DK2086944T3 (da) Fremgangsmåde til fremstilling af difluormethylpyrazolylcarboxylater
DK2054711T3 (da) Fremgangsmåde til fremstilling af mikroarrays
DK1863833T3 (da) Fremgangsmåde til fremstilling af makrocykliske forbindelser
DK1852430T3 (da) Fremgangsmåde til fremstilling af proanthocyanidinoligomer
DK2167613T3 (da) Fremgangsmåde til fremstilling af biobrændsler
DK2431359T3 (da) Fremgangsmåde til fremstilling af diaminophenothiaziniumforbindelser
BRPI0717596A2 (pt) Compostos de éter biarílico uréia
DK2044002T3 (da) Fremgangsmåde til fremstilling af 3-substituerede 2-amino-5-halobenzamider
ATE524477T1 (de) Aziridinylepothilonverbindungen
ATE480545T1 (de) Imidazo-verbindungen
AT504580A3 (de) Scan-einrichtung
DK2061746T3 (da) Fremgangsmåde til fremstilling af diestere
CR10161A (es) Inmunoglobulinas
ATE546437T1 (de) Aminomethyl-4-imidazole
DE502007000218D1 (de) nsetzungen
DK2029567T3 (da) Fremgangsmåde til frembringelse af benzopyran-2-ol-derivater
DE502007002453D1 (de) Kunstoffverdichtergehäuse
DK2213654T3 (da) Fremgangsmåde til fremstilling af 2-amino-5-brombenzamid derivater
FI20065363A0 (fi) Erotusmenetelmä
ITMI20060591A1 (it) Innesto rapido
DE502007000361D1 (de) Stanznieteinheit
DE502007001629D1 (de) Rfahren