DK2032598T3 - Axmi-031, axmi-039, axmi-040 og axmi-049, en familie af deltaendotoksingener og fremgangsmåder til deres anvendelse - Google Patents

Axmi-031, axmi-039, axmi-040 og axmi-049, en familie af deltaendotoksingener og fremgangsmåder til deres anvendelse

Info

Publication number
DK2032598T3
DK2032598T3 DK07812139.9T DK07812139T DK2032598T3 DK 2032598 T3 DK2032598 T3 DK 2032598T3 DK 07812139 T DK07812139 T DK 07812139T DK 2032598 T3 DK2032598 T3 DK 2032598T3
Authority
DK
Denmark
Prior art keywords
axmi
doctors
participation
family
procedures
Prior art date
Application number
DK07812139.9T
Other languages
English (en)
Inventor
Nadine Carozzi
Nicholas Duck
Theodore Kahn
Nalini Desai
Shruti Jain
Daniel John Tomso
Julia Thissen
Rong Guo
Original Assignee
Athenix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athenix Corp filed Critical Athenix Corp
Application granted granted Critical
Publication of DK2032598T3 publication Critical patent/DK2032598T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Pest Control & Pesticides (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
DK07812139.9T 2006-06-14 2007-06-14 Axmi-031, axmi-039, axmi-040 og axmi-049, en familie af deltaendotoksingener og fremgangsmåder til deres anvendelse DK2032598T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81377406P 2006-06-14 2006-06-14
PCT/US2007/071173 WO2007147029A2 (en) 2006-06-14 2007-06-14 Axmi-031, axmi-039, axmi-040 and axmi-049, a family of delta-endotoxin genes and methods for their use

Publications (1)

Publication Number Publication Date
DK2032598T3 true DK2032598T3 (da) 2013-01-21

Family

ID=38832836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07812139.9T DK2032598T3 (da) 2006-06-14 2007-06-14 Axmi-031, axmi-039, axmi-040 og axmi-049, en familie af deltaendotoksingener og fremgangsmåder til deres anvendelse

Country Status (12)

Country Link
US (3) US7923602B2 (da)
EP (1) EP2032598B1 (da)
CN (1) CN101501066B (da)
AR (2) AR061467A1 (da)
AU (1) AU2007260716B2 (da)
BR (1) BRPI0713646B1 (da)
DK (1) DK2032598T3 (da)
ES (1) ES2397118T3 (da)
HK (1) HK1129396A1 (da)
NZ (2) NZ594744A (da)
PL (1) PL2032598T3 (da)
WO (1) WO2007147029A2 (da)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009262153B2 (en) * 2008-06-25 2014-02-27 BASF Agricultural Solutions Seed US LLC Toxin genes and methods for their use
BRPI0924154A2 (pt) * 2009-01-23 2015-08-25 Pioneer Hi Bred Internacional Inc Mólecula de ácido nucleico isolada, construção de dna, célula hospedeira, planta transgênica, semente transformada, polipetídeo isolado com atividade pesticida, composição e métodos para controlar uma população de praga de insetos, para exterminar uma praga de insetos, para produzir um polipeptídeo com atividade pesticida e para proteger uma planta de uma praga.
WO2011089071A2 (de) 2010-01-22 2011-07-28 Bayer Cropscience Ag Akarizide und/oder insektizide wirkstoffkombinationen
AU2011218130B2 (en) 2010-02-18 2016-03-03 Athenix Corp. AXMI218, AXMI219, AXMI220, AXMI226, AXMI227, AXMI228, AXMI229, AXMI230, and AXMI231 delta-endotoxin genes and methods for their use
WO2012024372A2 (en) * 2010-08-20 2012-02-23 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis gene with coleopteran activity
JP2012082186A (ja) 2010-09-15 2012-04-26 Bayer Cropscience Ag 殺虫性アリールピロリジン類
BR112013006612A2 (pt) * 2010-09-22 2017-10-24 Bayer Ip Gmbh uso de agentes de controle biológico ou químico para controle de insetos e nematódeos em culturas resistentes
MX2013005258A (es) 2010-11-15 2013-07-05 Bayer Ip Gmbh N-aril pirazol(tio)carboxamidas.
US10851387B1 (en) * 2011-04-21 2020-12-01 Basf Agricultural Solutions Seed, Us Llc AXMI253 and AXMI254 toxin genes and methods for their use
US9139843B2 (en) * 2011-05-24 2015-09-22 Pioneer Hi Bred International Inc Endotoxins having nematocidal activity and methods of use thereof
BR112013033592A8 (pt) * 2011-06-30 2022-07-05 Athenix Corp Toxina nematoide axmi277 e métodos para a sua utilização
US9265252B2 (en) 2011-08-10 2016-02-23 Bayer Intellectual Property Gmbh Active compound combinations comprising specific tetramic acid derivatives
UA117731C2 (uk) * 2012-06-29 2018-09-25 Атенікс Корп. Токсин axmi277 проти нематод та його застосування
TWI654180B (zh) 2012-06-29 2019-03-21 美商艾佛艾姆希公司 殺真菌之雜環羧醯胺
BR112015005674B1 (pt) 2012-09-14 2022-09-06 BASF Agricultural Solutions Seed US LLC Polipeptídeos recombinantes para conferir tolerância à herbicidas
CN104884625A (zh) 2012-10-15 2015-09-02 先锋国际良种公司 增强cry内毒素的活性的方法和组合物
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
EP2735231A1 (en) 2012-11-23 2014-05-28 Bayer CropScience AG Active compound combinations
BR112015012473A2 (pt) 2012-11-30 2017-07-11 Bayer Cropscience Ag misturas binárias pesticidas e fungicidas
WO2014083089A1 (en) 2012-11-30 2014-06-05 Bayer Cropscience Ag Ternary fungicidal and pesticidal mixtures
MX2015006327A (es) 2012-11-30 2015-10-05 Bayer Cropscience Ag Mezclas fungicidas ternarias.
AR093909A1 (es) 2012-12-12 2015-06-24 Bayer Cropscience Ag Uso de ingredientes activos para controlar nematodos en cultivos resistentes a nematodos
DK2964767T3 (da) 2013-03-07 2020-03-23 BASF Agricultural Solutions Seed US LLC Toksingener og fremgangsmåder til anvendelse deraf
EP2970363B1 (en) 2013-03-14 2020-07-08 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US10023877B2 (en) 2013-03-15 2018-07-17 Pioneer Hi-Bred International, Inc. PHI-4 polypeptides and methods for their use
AR097280A1 (es) * 2013-08-09 2016-03-02 Athenix Corp Gen de la toxina axmi422 y sus métodos de empleo
EP3032942B1 (en) 2013-08-16 2020-03-11 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3043635B1 (en) 2013-09-13 2020-02-12 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
UA122475C2 (uk) * 2013-12-09 2020-11-10 Атенікс Корп. Ген токсину ахмі486 та спосіб його застосування
WO2015120276A1 (en) 2014-02-07 2015-08-13 Pioneer Hi Bred International Inc Insecticidal proteins and methods for their use
EP3102684B1 (en) 2014-02-07 2020-05-06 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
BR112016020889B1 (pt) 2014-03-11 2022-10-04 BASF Agricultural Solutions Seed US LLC Molécula de ácido nucleico recombinante, célula hospedeira bacteriana, proteína hppd recombinante, uso do ácido nucleico recombinante e produto de base
WO2016000237A1 (en) 2014-07-03 2016-01-07 Pioneer Overseas Corporation Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
WO2016007355A1 (en) * 2014-07-07 2016-01-14 Aroian Raffi Van Anthelmintic probiotic compositions and methods
US10940170B2 (en) 2014-07-07 2021-03-09 University Of Massachusetts Anthelmintic probiotic compositions and methods
WO2016044092A1 (en) 2014-09-17 2016-03-24 Pioneer Hi Bred International Inc Compositions and methods to control insect pests
US10435706B2 (en) 2014-10-16 2019-10-08 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
BR112017013633A2 (pt) * 2014-12-22 2018-03-13 Agbiome Inc polipeptídeo recombinante, molécula de ácido nucleico recombinante, composição, célula hospedeira, construto de dna, vetor, método para controlar uma população de pragas, método para produzir um polipeptídeo com atividade pesticida, planta, semente transgênica, método para proteger uma planta de uma praga de insetos, método para aumentar o rendimento em uma planta
EA038923B1 (ru) 2015-03-11 2021-11-10 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидная днк-конструкция и способы её применения
WO2016168289A1 (en) 2015-04-17 2016-10-20 AgBiome, Inc. Pesticidal genes and methods of use
RU2738424C2 (ru) 2015-04-22 2020-12-14 Агбайоми, Инк. Пестицидные гены и способы их применения
RU2017144238A (ru) 2015-05-19 2019-06-19 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидные белки и способы их применения
CN108271390A (zh) 2015-06-03 2018-07-10 农业生物群落股份有限公司 杀虫基因和使用方法
AU2016278142A1 (en) 2015-06-16 2017-11-30 E. I. Du Pont De Nemours And Company Compositions and methods to control insect pests
CA2989169A1 (en) 2015-06-22 2016-12-29 AgBiome, Inc. Pesticidal genes and methods of use
MX2018000615A (es) 2015-07-13 2018-08-01 Pivot Bio Inc Metodos y composiciones para mejorar atributos de plantas.
MX2018001523A (es) 2015-08-06 2018-03-15 Pioneer Hi Bred Int Proteinas insecticidas derivadas de plantas y metodos para su uso.
CN114032251A (zh) 2015-08-07 2022-02-11 拜尔作物科学公司 根优先和胁迫诱导型启动子及其用途
EP3341483B1 (en) 2015-08-28 2019-12-18 Pioneer Hi-Bred International, Inc. Ochrobactrum-mediated transformation of plants
WO2017062412A1 (en) 2015-10-05 2017-04-13 Massachusetts Institute Of Technology Nitrogen fixation using refactored nif clusters
US10435707B2 (en) * 2015-10-14 2019-10-08 Basf Agricultural Solutions Seed, Us Llc AXMI554 delta-endotoxin gene and methods for its use
US20180325119A1 (en) 2015-12-18 2018-11-15 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US10358654B2 (en) 2015-12-22 2019-07-23 AgBiome, Inc. Pesticidal genes and methods of use
CN117003840A (zh) 2016-04-14 2023-11-07 先锋国际良种公司 具有改善的活性谱的杀昆虫多肽及其用途
US11028407B2 (en) 2016-04-19 2021-06-08 Pioneer Hi-Bred International, Inc. Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof
EP3960863A1 (en) 2016-05-04 2022-03-02 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US20190185867A1 (en) 2016-06-16 2019-06-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
US20190194676A1 (en) 2016-06-24 2019-06-27 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
EP3954202A1 (en) 2016-07-01 2022-02-16 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
US20210292778A1 (en) 2016-07-12 2021-09-23 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests
CA3035896A1 (en) 2016-09-06 2018-03-15 AgBiome, Inc. Pesticidal genes and methods of use
EP4050021A1 (en) 2016-11-01 2022-08-31 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN110267975B (zh) 2016-11-23 2024-04-19 巴斯夫农业种子解决方案美国有限责任公司 Axmi669和axmi991毒素基因及其使用方法
CN110088123B (zh) 2016-12-14 2023-10-20 先锋国际良种公司 杀昆虫蛋白及其使用方法
US11555202B2 (en) 2016-12-22 2023-01-17 BASF Agricultural Solutions Seed US LLC Elite event EE-GM5 and methods and kits for identifying such event in biological samples
CA3046232A1 (en) * 2016-12-22 2018-06-28 BASF Agricultural Solutions Seed US LLC Elite event ee-gm4 and methods and kits for identifying such event in biological samples
KR20190095411A (ko) * 2016-12-22 2019-08-14 바스프 아그리컬쳐럴 솔루션즈 시드 유에스 엘엘씨 선충 해충의 방제를 위한 ｃｒｙ１４의 용도
CA3046226A1 (en) 2016-12-22 2018-06-28 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN110799474B (zh) 2017-01-12 2022-07-26 皮沃特生物公司 用于改良植物性状的方法及组合物
CA3049775A1 (en) 2017-01-18 2018-07-26 BASF Agricultural Solutions Seed US LLC Bp005 toxin gene and methods for its use
UY37570A (es) 2017-01-18 2018-08-31 Bayer Cropscience Lp Uso de bp005 para el control de patógenos de planta
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
US10793610B2 (en) 2017-01-30 2020-10-06 AgBiome, Inc. Pesticidal genes and methods of use
WO2018148001A1 (en) 2017-02-08 2018-08-16 Pioneer Hi-Bred International Inc Insecticidal combinations of plant derived insecticidal proteins and methods for their use
CA3055389A1 (en) 2017-03-07 2018-09-13 BASF Agricultural Solutions Seed US LLC Hppd variants and methods of use
US11708565B2 (en) 2017-03-07 2023-07-25 BASF Agricultural Solutions Seesi US LLC HPPD variants and methods of use
BR112019018059A2 (pt) 2017-03-07 2020-08-04 BASF Agricultural Solutions Seed US LLC molécula de ácido nucleico recombinante, célula hospedeira, plantas, sementes transgênicas, polipeptídeo recombinante, método para produzir um polipeptídeo, método de controle de ervas daninhas, uso do ácido nucleico e produto de utilidade
CA3058757A1 (en) 2017-04-11 2018-10-18 AgBiome, Inc. Pesticidal genes and methods of use
EP3630150A4 (en) 2017-05-23 2021-04-28 University of Massachusetts PURIFIED ANTHELMINTIC COMPOSITIONS AND RELATED PROCEDURES
BR112019024827A2 (pt) 2017-05-26 2020-06-16 Pioneer Hi-Bred International, Inc. Construto de dna, planta transgênica ou progênie da mesma, composição e método para controlar uma população de pragas de insetos
EP3661950A2 (en) 2017-08-03 2020-06-10 Agbiome, Inc. Pesticidal genes and methods of use
CN107828817B (zh) * 2017-09-29 2021-02-19 杭州瑞丰生物科技有限公司 一种利用Bt蛋白防治农作物半翅目害虫的方法
US20200165626A1 (en) 2017-10-13 2020-05-28 Pioneer Hi-Bred International, Inc. Virus-induced gene silencing technology for insect control in maize
WO2019083810A1 (en) 2017-10-24 2019-05-02 Basf Se IMPROVING HERBICIDE TOLERANCE FOR 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (HPPD) INHIBITORS BY NEGATIVE REGULATION OF HPPD EXPRESSION IN SOYBEANS
US20210032651A1 (en) 2017-10-24 2021-02-04 Basf Se Improvement of herbicide tolerance to hppd inhibitors by down-regulation of putative 4-hydroxyphenylpyruvate reductases in soybean
US11993778B2 (en) 2017-10-25 2024-05-28 Pivot Bio, Inc. Methods and compositions for improving engineered microbes that fix nitrogen
WO2019126479A1 (en) 2017-12-22 2019-06-27 AgBiome, Inc. Pesticidal genes and methods of use
EP3755797A1 (en) 2018-02-22 2020-12-30 Zymergen, Inc. Method for creating a genomic library enriched for bacillus and identification of novel cry toxins
WO2019169227A1 (en) 2018-03-02 2019-09-06 Zymergen Inc. Insecticidal protein discovery platform and insecticidal proteins discovered therefrom
US20210002657A1 (en) 2018-03-02 2021-01-07 Pioneer Hi-Bred International, Inc. Plant health assay
BR112020021445A2 (pt) 2018-04-20 2021-01-19 AgBiome, Inc. Genes pesticidas e métodos de uso
CA3096516A1 (en) 2018-05-22 2019-11-28 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
EP3810763A4 (en) * 2018-05-25 2022-03-30 Basf Agricultural Solutions Seed Us Llc PLANTS WITH ELITE EVENT EE-GM4 AND METHODS AND KITS FOR IDENTIFYING SUCH EVENT IN BIOLOGICAL SAMPLES AND THEIR TREATMENT
CA3098989A1 (en) * 2018-05-25 2019-11-28 BASF Agricultural Solutions Seed US LLC Plants containing elite event ee-gm5 and methods and kits for identifying such event in biological samples, and treatment thereof
BR112020024863A2 (pt) 2018-06-05 2022-02-01 Lifeedit Inc Nucleases guiadas por rna, fragmentos ativos e variantes das mesmas e métodos de uso
EP3844283A1 (en) 2018-08-29 2021-07-07 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
KR20210149686A (ko) 2018-12-27 2021-12-09 라이프에디트 테라퓨틱스, 인크. 유전자 편집에 유용한 폴리펩티드 및 사용 방법
MX2022001849A (es) 2019-08-12 2022-03-11 Lifeedit Therapeutics Inc Nucleasas guiadas por acido ribonucleico (arn) y sus fragmentos activos y variantes y metodos de uso.
WO2021076346A1 (en) 2019-10-18 2021-04-22 Pioneer Hi-Bred International, Inc. Maize event dp-202216-6 and dp-023211-2 stack
CN115190912A (zh) 2019-12-30 2022-10-14 生命编辑制药股份有限公司 Rna指导核酸酶及其活性片段与变体以及使用方法
US20230263121A1 (en) 2020-03-31 2023-08-24 Elo Life Systems Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
TW202208626A (zh) 2020-04-24 2022-03-01 美商生命編輯公司 Rna引導核酸酶及其活性片段與變體，以及使用方法
CA3173882A1 (en) 2020-05-11 2021-11-18 Alexandra Briner CRAWLEY Rna-guided nucleic acid binding proteins and active fragments and variants thereof and methods of use
US20230235352A1 (en) 2020-07-14 2023-07-27 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CA3173949A1 (en) 2020-07-15 2022-01-20 LifeEDIT Therapeutics, Inc. Uracil stabilizing proteins and active fragments and variants thereof and methods of use
EP4192848A1 (en) 2020-08-10 2023-06-14 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
JP2023541400A (ja) 2020-09-11 2023-10-02 ライフエディット セラピューティクス，インコーポレイティド Ｄｎａ修飾酵素並びにその活性断片及びバリアント並びにその使用方法
MX2023004761A (es) 2020-10-23 2023-07-17 Elo Life Systems Inc Metodos para producir plantas de vainilla con mejor sabor y produccion agronomica.
EP4251755A2 (en) 2020-11-24 2023-10-04 AgBiome, Inc. Pesticidal genes and methods of use
TW202300649A (zh) 2021-03-22 2023-01-01 美商生命編輯治療學公司 Ｄｎａ修飾酶及活性片段及其變體及使用方法
CA3214227A1 (en) 2021-05-06 2022-11-10 Rebekah Deter Kelly Pesticidal genes and methods of use
CA3173953A1 (en) 2021-06-11 2023-12-10 Tyson D. BOWEN Rna polymerase iii promoters and methods of use
CA3239251A1 (en) 2021-12-07 2023-06-15 Rebekah Deter Kelly Pesticidal genes and methods of use
WO2023139557A1 (en) 2022-01-24 2023-07-27 LifeEDIT Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
WO2023154887A1 (en) 2022-02-11 2023-08-17 Northeast Agricultural University Methods and compositions for increasing protein and/or oil content and modifying oil profile in a plant
WO2024033901A1 (en) 2022-08-12 2024-02-15 LifeEDIT Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
WO2024044596A1 (en) 2022-08-23 2024-02-29 AgBiome, Inc. Pesticidal genes and methods of use
WO2024042489A1 (en) 2022-08-25 2024-02-29 LifeEDIT Therapeutics, Inc. Chemical modification of guide rnas with locked nucleic acid for rna guided nuclease-mediated gene editing
WO2024095245A2 (en) 2022-11-04 2024-05-10 LifeEDIT Therapeutics, Inc. Evolved adenine deaminases and rna-guided nuclease fusion proteins with internal insertion sites and methods of use
WO2024129674A1 (en) 2022-12-13 2024-06-20 AgBiome, Inc. Pesticidal genes and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281530A (en) * 1987-08-12 1994-01-25 Mycogen Corporation Genes encoding nematode-active toxins cloned from bacillus thuringiensis isolate PS17
US5753492A (en) * 1987-08-12 1998-05-19 Mycogen Corporation Genes encoding nematode-active toxins from Bacillus thuringiensis strains
US5831011A (en) * 1990-07-27 1998-11-03 Mycogen Corporation Bacillus thuringiensis genes encoding nematode-active toxins
US5589382A (en) * 1990-07-27 1996-12-31 Mycogen Corporation Bacillus thuringiensis genes encoding nematode-active toxins
US5743477A (en) 1992-08-27 1998-04-28 Dowelanco Insecticidal proteins and method for plant protection
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
US7253343B2 (en) 2003-08-28 2007-08-07 Athenix Corporation AXMI-003, a delta-endotoxin gene and methods for its use
US20050183161A1 (en) * 2003-10-14 2005-08-18 Athenix Corporation AXMI-010, a delta-endotoxin gene and methods for its use

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AR111197A2 (es) 2019-06-12
US8147856B2 (en) 2012-04-03
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WO2007147029A3 (en) 2008-06-19
US20120167251A1 (en) 2012-06-28
AR061467A1 (es) 2008-08-27
US7923602B2 (en) 2011-04-12
AU2007260716B2 (en) 2013-05-02
WO2007147029A2 (en) 2007-12-21
CN101501066B (zh) 2012-05-30
BRPI0713646A2 (pt) 2012-10-23
EP2032598B1 (en) 2012-10-17
CN101501066A (zh) 2009-08-05
AU2007260716A1 (en) 2007-12-21
PL2032598T3 (pl) 2013-08-30
ES2397118T3 (es) 2013-03-04
EP2032598A2 (en) 2009-03-11
US20070294787A1 (en) 2007-12-20
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