DK2010563T3 - Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi - Google Patents

Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi

Info

Publication number
DK2010563T3
DK2010563T3 DK06724141.4T DK06724141T DK2010563T3 DK 2010563 T3 DK2010563 T3 DK 2010563T3 DK 06724141 T DK06724141 T DK 06724141T DK 2010563 T3 DK2010563 T3 DK 2010563T3
Authority
DK
Denmark
Prior art keywords
protein
proteins
nucleic acid
relates
substitution therapy
Prior art date
Application number
DK06724141.4T
Other languages
English (en)
Inventor
Franco Antonio Laccone
Original Assignee
Univ Goettingen Georg August
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Goettingen Georg August filed Critical Univ Goettingen Georg August
Application granted granted Critical
Publication of DK2010563T3 publication Critical patent/DK2010563T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK06724141.4T 2006-04-07 2006-04-07 Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi DK2010563T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2006/003203 WO2007115578A1 (en) 2006-04-07 2006-04-07 Synthetic mecp2 sequence for protein substitution therapy

Publications (1)

Publication Number Publication Date
DK2010563T3 true DK2010563T3 (da) 2011-05-23

Family

ID=36589309

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06724141.4T DK2010563T3 (da) 2006-04-07 2006-04-07 Syntetisk MeCP2 sekvens til proteinsubstitutionsterapi

Country Status (16)

Country Link
US (1) US8226930B2 (da)
EP (1) EP2010563B1 (da)
JP (1) JP5102283B2 (da)
CN (1) CN101415726B (da)
AT (1) ATE500265T1 (da)
AU (1) AU2006341726B2 (da)
CA (1) CA2647125C (da)
DE (1) DE602006020501D1 (da)
DK (1) DK2010563T3 (da)
ES (1) ES2362195T3 (da)
HK (1) HK1121468A1 (da)
HR (1) HRP20110386T1 (da)
IL (1) IL194274A (da)
PL (1) PL2010563T3 (da)
SI (1) SI2010563T1 (da)
WO (1) WO2007115578A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1398191B1 (it) * 2010-02-17 2013-02-14 Ist Superiore Sanita Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).
AU2011325956B2 (en) 2010-11-12 2016-07-14 The General Hospital Corporation Polycomb-associated non-coding RNAs
US9920317B2 (en) 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs
CN104540946A (zh) 2012-05-16 2015-04-22 Rana医疗有限公司 用于调节utrn表达的组合物和方法
EP2850188A4 (en) 2012-05-16 2016-01-20 Rana Therapeutics Inc COMPOSITIONS AND METHODS FOR MODULATING THE EXPRESSION OF THE MULTIGENIC FAMILY OF HEMOGLOBIN
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
CN104583401A (zh) 2012-05-16 2015-04-29 Rana医疗有限公司 用于调节atp2a2表达的组合物和方法
EA201492116A1 (ru) 2012-05-16 2015-05-29 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии mecp2
EA201492123A1 (ru) 2012-05-16 2015-10-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии семейства генов smn
WO2014130408A1 (en) * 2013-02-20 2014-08-28 The Research Foundation For The State University Of New York Regulators of rab5 activity
CA2966044A1 (en) 2014-10-30 2016-05-06 The General Hospital Corporation Methods for modulating atrx-dependent gene repression
WO2016149455A2 (en) 2015-03-17 2016-09-22 The General Hospital Corporation The rna interactome of polycomb repressive complex 1 (prc1)
TWI601821B (zh) * 2016-04-15 2017-10-11 中央研究院 治療神經發展性疾病
US20210101938A1 (en) * 2017-03-24 2021-04-08 The University Court Of The University Of Edinburgh Mecp2 based therapy
WO2019079462A1 (en) * 2017-10-17 2019-04-25 President And Fellows Of Harvard College TRANSCRIPTION MODULATION SYSTEMS BASED ON CAS9
KR102052097B1 (ko) * 2017-11-30 2019-12-05 한국과학기술연구원 Mecp2 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물
KR20220003553A (ko) * 2019-04-24 2022-01-10 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 레트 증후군의 치료에 유용한 조성물
WO2023235648A1 (en) * 2022-06-03 2023-12-07 The Regents Of The University Of California Nuclear Delivery and Transcriptional Repression with a Cell-penetrant MeCP2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2364690A1 (en) * 1999-02-28 2000-10-19 Washington University Novel transduction molecules and methods for using same
US6709817B1 (en) * 1999-09-07 2004-03-23 Baylor College Of Medicine Method of screening Rett syndrome by detecting a mutation in MECP2
EP1385887A4 (en) * 2001-04-20 2006-12-06 Univ Yonsei Seoul REPRESSORS OF THE HIV TRANSCRIPTION AND METHOD THEREFOR
WO2005078099A1 (en) 2004-02-17 2005-08-25 The Hospital For Sick Children Mecp2e1 gene

Also Published As

Publication number Publication date
CA2647125A1 (en) 2007-10-18
CN101415726A (zh) 2009-04-22
SI2010563T1 (sl) 2011-07-29
CN101415726B (zh) 2013-07-31
AU2006341726B2 (en) 2012-09-20
JP2009532045A (ja) 2009-09-10
CA2647125C (en) 2015-02-03
US8226930B2 (en) 2012-07-24
EP2010563B1 (en) 2011-03-02
US20090233856A1 (en) 2009-09-17
JP5102283B2 (ja) 2012-12-19
WO2007115578A1 (en) 2007-10-18
WO2007115578A8 (en) 2008-10-30
ES2362195T3 (es) 2011-06-29
IL194274A (en) 2011-07-31
EP2010563A1 (en) 2009-01-07
AU2006341726A1 (en) 2007-10-18
PL2010563T3 (pl) 2011-11-30
HRP20110386T1 (hr) 2011-08-31
HK1121468A1 (en) 2009-04-24
ATE500265T1 (de) 2011-03-15
DE602006020501D1 (de) 2011-04-14

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