DK176000B1 - Fremgangsmåde til fremstilling af et protein ud fra gærsvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmåden - Google Patents

Fremgangsmåde til fremstilling af et protein ud fra gærsvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmåden Download PDF

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Publication number
DK176000B1
DK176000B1 DK198903262A DK326289A DK176000B1 DK 176000 B1 DK176000 B1 DK 176000B1 DK 198903262 A DK198903262 A DK 198903262A DK 326289 A DK326289 A DK 326289A DK 176000 B1 DK176000 B1 DK 176000B1
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Denmark
Prior art keywords
receptor
yeast
sequence
ligand
plasmid
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DK198903262A
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Danish (da)
English (en)
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DK326289A (da
DK326289D0 (da
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Pierre Henry Chambon
Daniel Metzger
John White
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Centre Nat Rech Scient
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Instructional Devices (AREA)
  • Prostheses (AREA)
DK198903262A 1988-07-01 1989-06-30 Fremgangsmåde til fremstilling af et protein ud fra gærsvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmåden DK176000B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8808978A FR2634495B1 (fr) 1988-07-01 1988-07-01 Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes
FR8808978 1988-07-01

Publications (3)

Publication Number Publication Date
DK326289D0 DK326289D0 (da) 1989-06-30
DK326289A DK326289A (da) 1990-01-02
DK176000B1 true DK176000B1 (da) 2005-11-14

Family

ID=9368010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198903262A DK176000B1 (da) 1988-07-01 1989-06-30 Fremgangsmåde til fremstilling af et protein ud fra gærsvampe under anvendelse af et inducerbart system, samt vektorer og transformerede stammer til brug ved fremgangsmåden

Country Status (10)

Country Link
US (2) US5817503A (el)
EP (1) EP0349435B1 (el)
JP (1) JP2973430B2 (el)
AT (1) ATE123068T1 (el)
CA (1) CA1341192C (el)
DE (1) DE68922790T2 (el)
DK (1) DK176000B1 (el)
ES (1) ES2075068T3 (el)
FR (1) FR2634495B1 (el)
GR (1) GR3016996T3 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879926A (en) * 1989-03-31 1999-03-09 Transgene S.A. Yeast strains for the production of mature heterologous proteins, especially hirudin
FR2645174B1 (fr) * 1989-03-31 1994-01-07 Transgene Sa Souches de levure ameliorees pour la production de proteines heterologues matures en particulier d'hirudine et procede de preparation d'hirudine correspondant
FR2645175B1 (fr) * 1989-03-31 1994-02-18 Transgene Sa Souche de saccharomyces cerevisiaeproductrice d'une proteine heterologue et procede de preparation de ladite proteine heterologue par fermentation de ladite souche
FR2649994A1 (fr) * 1989-06-30 1991-01-25 Aderegem Procede d'obtention d'un recepteur humain natif sauvage des oestrogenes et ses applications
EP0441483A3 (en) * 1990-01-16 1992-11-19 Baylor College Of Medicine Expression vectors that produce steroid receptors, steroid receptor chimera, screening assays for steroid receptors and clinical assays using synthesized receptors and receptor vectors
US5733732A (en) * 1996-01-03 1998-03-31 University Of Iowa Research Foundation Methods for detecting primary adhalinopathy
ATE366745T1 (de) * 1999-12-07 2007-08-15 Sumitomo Chemical Co Mutant er-alpha und nachweissysteme für transaktivierung
US6737262B1 (en) * 2000-07-11 2004-05-18 Robert I. Bolla Animal feed containing polypeptides
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
EP1585807A4 (en) * 2002-12-23 2006-05-24 Glycofi Inc MODULATION OF THE GENE EXPRESSION STERO RECEPTOR

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
MY103358A (en) * 1987-04-15 1993-06-30 Novartis Ag Process for the production of protiens.

Also Published As

Publication number Publication date
EP0349435B1 (fr) 1995-05-24
ATE123068T1 (de) 1995-06-15
JPH02242693A (ja) 1990-09-27
US5817503A (en) 1998-10-06
EP0349435A1 (fr) 1990-01-03
DE68922790D1 (de) 1995-06-29
DK326289A (da) 1990-01-02
ES2075068T3 (es) 1995-10-01
CA1341192C (fr) 2001-02-27
JP2973430B2 (ja) 1999-11-08
US6444438B1 (en) 2002-09-03
FR2634495A1 (fr) 1990-01-26
DK326289D0 (da) 1989-06-30
FR2634495B1 (fr) 1990-10-26
DE68922790T2 (de) 1995-11-30
GR3016996T3 (en) 1995-11-30

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