DK174017B1 - Anvendelse af gamma-hydroxysmørsyresalte til fremstilling af farmaceutiske præparater til behandling af alkoholisme - Google Patents
Anvendelse af gamma-hydroxysmørsyresalte til fremstilling af farmaceutiske præparater til behandling af alkoholisme Download PDFInfo
- Publication number
- DK174017B1 DK174017B1 DK198902723A DK272389A DK174017B1 DK 174017 B1 DK174017 B1 DK 174017B1 DK 198902723 A DK198902723 A DK 198902723A DK 272389 A DK272389 A DK 272389A DK 174017 B1 DK174017 B1 DK 174017B1
- Authority
- DK
- Denmark
- Prior art keywords
- alcohol
- hydroxybutyric acid
- treatment
- alcoholism
- naghb
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20859/88A IT1217783B (it) | 1988-06-03 | 1988-06-03 | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
| IT2085988 | 1988-06-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK272389D0 DK272389D0 (da) | 1989-06-02 |
| DK272389A DK272389A (da) | 1989-12-04 |
| DK174017B1 true DK174017B1 (da) | 2002-04-15 |
Family
ID=11173141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198902723A DK174017B1 (da) | 1988-06-03 | 1989-06-02 | Anvendelse af gamma-hydroxysmørsyresalte til fremstilling af farmaceutiske præparater til behandling af alkoholisme |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4983632A (it) |
| EP (1) | EP0344704B1 (it) |
| AR (1) | AR241512A1 (it) |
| AT (1) | ATE126433T1 (it) |
| AU (1) | AU633002B2 (it) |
| CA (1) | CA1330423C (it) |
| DE (1) | DE68923819T2 (it) |
| DK (1) | DK174017B1 (it) |
| ES (1) | ES2075011T3 (it) |
| FI (1) | FI892718A (it) |
| GR (1) | GR3018009T3 (it) |
| IT (1) | IT1217783B (it) |
| NO (1) | NO892270L (it) |
| NZ (1) | NZ229399A (it) |
| PT (1) | PT90732B (it) |
| ZA (1) | ZA894128B (it) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5153219A (en) * | 1991-04-22 | 1992-10-06 | Morris D. Faiman | Thiocarbamate sulfoxide composition for deterring ethanol ingestion |
| IT1248588B (it) * | 1991-06-28 | 1995-01-19 | Gaetano Crepaldi | Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. |
| WO1993002682A1 (en) * | 1991-08-06 | 1993-02-18 | Labco Pharmaceuticals, Inc. | Method and compositions for reducing craving for alcohol and stimulants |
| US5366990A (en) * | 1991-11-14 | 1994-11-22 | Reid Larry D | Method for treating alcohol abuse and alcoholism |
| IT1261432B (it) * | 1993-03-26 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Uso di acil l- carnitina gammaidrossibutirrato per il trattamento dell'alcolismo. |
| IT1261485B (it) * | 1993-06-24 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Uso di acil l-carnitine gamma-idrossibutirrato per il trattamento di tossicodipendenze. |
| IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
| IT1283782B1 (it) * | 1996-08-09 | 1998-04-30 | Ct Lab Farm Srl | Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo |
| DK1140061T3 (da) * | 1998-12-23 | 2003-08-25 | Orphan Medical Inc | Mikrobiologisk sunde og stabile opløsninger af gamma-hydroxybutyratsalt til behandling af narcolepsi |
| EP1316309A1 (en) * | 1998-12-23 | 2003-06-04 | Orphan Medical Inc. | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy |
| DE60019435T2 (de) * | 1999-09-14 | 2006-02-23 | Tepha, Inc., Cambridge | Therapeutische anwendung von polymere die gamma-hydroxybutyrat enthalten |
| ITMI20020754A1 (it) * | 2002-04-09 | 2003-10-09 | Aboca S P A | Composizioni effervescenti contenenti succhi di frutta essicati |
| CA2525132C (en) | 2003-05-08 | 2011-06-28 | Tepha, Inc. | Polyhydroxyalkanoate medical textiles and fibers |
| ATE473021T1 (de) | 2004-08-03 | 2010-07-15 | Tepha Inc | Nichtkräuselnde polyhydroxyalkanoatnähte |
| US7838556B2 (en) * | 2006-02-21 | 2010-11-23 | University Of Maryland, Baltimore | Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands |
| CA2664985A1 (en) * | 2006-09-29 | 2008-04-10 | The Board Of Trustees Of The University Of Illinois | Histone acetyl transferase activators and histone deacetylase inhibitors in the treatment of alcoholism |
| US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
| US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
| US8771735B2 (en) | 2008-11-04 | 2014-07-08 | Jazz Pharmaceuticals, Inc. | Immediate release dosage forms of sodium oxybate |
| FR2938431B1 (fr) * | 2008-11-14 | 2013-12-20 | Debregeas Et Associes Pharma | Nouvelle composition a base d'acide gamma-hydroxybutyrique |
| FR2949061B1 (fr) | 2009-08-12 | 2013-04-19 | Debregeas Et Associes Pharma | Microgranules flottants |
| FR2949062B1 (fr) | 2009-08-12 | 2011-09-02 | Debregeas Et Associes Pharma | Nouvelles formulations pharmaceutiques contre le mesusage des medicaments |
| MX2012011022A (es) | 2010-03-24 | 2013-02-26 | Jazz Pharmaceuticals Inc | Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas. |
| MX340591B (es) * | 2010-05-04 | 2016-07-15 | Jazz Pharmaceuticals Inc * | Formulaciones de liberacion inmediata y formas de dosis de gamma-hidroxibutirato. |
| US8591922B1 (en) | 2012-12-14 | 2013-11-26 | Jazz Pharmacuticals, Inc. | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
| US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
| ES2807178T3 (es) | 2014-08-15 | 2021-02-22 | Tepha Inc | Suturas de autorretención de poli-4-hidroxibutirato y copolímeros del mismo |
| US9555155B2 (en) | 2014-12-11 | 2017-01-31 | Tepha, Inc. | Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof |
| US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
| KR20210094513A (ko) | 2018-11-19 | 2021-07-29 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 알코올-내성 약물 제형 |
| US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0044801B1 (de) * | 1980-07-17 | 1984-02-15 | Josef Dr. Klosa | Nichthygroskopische Salze der 4-Hydroxybuttersäure, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Mittel |
-
1988
- 1988-06-03 IT IT20859/88A patent/IT1217783B/it active
-
1989
- 1989-05-30 DE DE68923819T patent/DE68923819T2/de not_active Expired - Lifetime
- 1989-05-30 AT AT89109712T patent/ATE126433T1/de not_active IP Right Cessation
- 1989-05-30 ES ES89109712T patent/ES2075011T3/es not_active Expired - Lifetime
- 1989-05-30 ZA ZA894128A patent/ZA894128B/xx unknown
- 1989-05-30 EP EP89109712A patent/EP0344704B1/en not_active Expired - Lifetime
- 1989-06-01 AU AU35904/89A patent/AU633002B2/en not_active Expired
- 1989-06-02 AR AR89314068A patent/AR241512A1/es active
- 1989-06-02 FI FI892718A patent/FI892718A/fi not_active Application Discontinuation
- 1989-06-02 CA CA000601648A patent/CA1330423C/en not_active Expired - Lifetime
- 1989-06-02 NZ NZ229399A patent/NZ229399A/en unknown
- 1989-06-02 US US07/361,490 patent/US4983632A/en not_active Expired - Lifetime
- 1989-06-02 DK DK198902723A patent/DK174017B1/da not_active IP Right Cessation
- 1989-06-02 NO NO89892270A patent/NO892270L/no unknown
- 1989-06-02 PT PT90732A patent/PT90732B/pt not_active IP Right Cessation
-
1995
- 1995-11-08 GR GR950403119T patent/GR3018009T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT90732A (pt) | 1989-12-29 |
| IT8820859A0 (it) | 1988-06-03 |
| ES2075011T3 (es) | 1995-10-01 |
| GR3018009T3 (en) | 1996-02-29 |
| FI892718A0 (fi) | 1989-06-02 |
| AU633002B2 (en) | 1993-01-21 |
| IT1217783B (it) | 1990-03-30 |
| ATE126433T1 (de) | 1995-09-15 |
| DE68923819T2 (de) | 1996-01-18 |
| FI892718A (fi) | 1989-12-04 |
| AU3590489A (en) | 1989-12-07 |
| DE68923819D1 (de) | 1995-09-21 |
| NO892270D0 (no) | 1989-06-02 |
| CA1330423C (en) | 1994-06-28 |
| DK272389A (da) | 1989-12-04 |
| EP0344704A1 (en) | 1989-12-06 |
| ZA894128B (en) | 1990-03-28 |
| DK272389D0 (da) | 1989-06-02 |
| US4983632A (en) | 1991-01-08 |
| PT90732B (pt) | 1994-10-31 |
| NO892270L (no) | 1989-12-04 |
| EP0344704B1 (en) | 1995-08-16 |
| NZ229399A (en) | 1997-02-24 |
| AR241512A1 (es) | 1992-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |