ES2075011T3 - Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas. - Google Patents

Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas.

Info

Publication number
ES2075011T3
ES2075011T3 ES89109712T ES89109712T ES2075011T3 ES 2075011 T3 ES2075011 T3 ES 2075011T3 ES 89109712 T ES89109712 T ES 89109712T ES 89109712 T ES89109712 T ES 89109712T ES 2075011 T3 ES2075011 T3 ES 2075011T3
Authority
ES
Spain
Prior art keywords
alcoholism
gamma
treatment
acid salts
prepare pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89109712T
Other languages
English (en)
Inventor
Gian Luigi Gessa
Fabio Fadda
Di Campochiaro Chiara Mormile
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ct Lab Farm Srl
Laboratorio Farmaceutico CT SRL
Original Assignee
Ct Lab Farm Srl
Laboratorio Farmaceutico CT SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Lab Farm Srl, Laboratorio Farmaceutico CT SRL filed Critical Ct Lab Farm Srl
Application granted granted Critical
Publication of ES2075011T3 publication Critical patent/ES2075011T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EL USO DE SALES ACIDAS DE GAMA-HIDROXIBUTILIRICA PARA PREPARAR COMPOSICIONES FARMACEUTICAS PARA LA LIBERACION DEL CONSUMO DE ALCOHOL ETILENO Y LA COMPOSICION OBTENIDA.
ES89109712T 1988-06-03 1989-05-30 Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas. Expired - Lifetime ES2075011T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20859/88A IT1217783B (it) 1988-06-03 1988-06-03 Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative

Publications (1)

Publication Number Publication Date
ES2075011T3 true ES2075011T3 (es) 1995-10-01

Family

ID=11173141

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89109712T Expired - Lifetime ES2075011T3 (es) 1988-06-03 1989-05-30 Uso de sales del acido gamma-hidroxibutirico para preparar composiciones farmaceuticas para uso en el tratamiento del alcoholismo, y las composiciones obtenidas.

Country Status (16)

Country Link
US (1) US4983632A (es)
EP (1) EP0344704B1 (es)
AR (1) AR241512A1 (es)
AT (1) ATE126433T1 (es)
AU (1) AU633002B2 (es)
CA (1) CA1330423C (es)
DE (1) DE68923819T2 (es)
DK (1) DK174017B1 (es)
ES (1) ES2075011T3 (es)
FI (1) FI892718A (es)
GR (1) GR3018009T3 (es)
IT (1) IT1217783B (es)
NO (1) NO892270L (es)
NZ (1) NZ229399A (es)
PT (1) PT90732B (es)
ZA (1) ZA894128B (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153219A (en) * 1991-04-22 1992-10-06 Morris D. Faiman Thiocarbamate sulfoxide composition for deterring ethanol ingestion
IT1248588B (it) * 1991-06-28 1995-01-19 Gaetano Crepaldi Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari.
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants
US5366990A (en) * 1991-11-14 1994-11-22 Reid Larry D Method for treating alcohol abuse and alcoholism
IT1261432B (it) * 1993-03-26 1996-05-23 Sigma Tau Ind Farmaceuti Uso di acil l- carnitina gammaidrossibutirrato per il trattamento dell'alcolismo.
IT1261485B (it) * 1993-06-24 1996-05-23 Sigma Tau Ind Farmaceuti Uso di acil l-carnitine gamma-idrossibutirrato per il trattamento di tossicodipendenze.
IT1266565B1 (it) * 1993-07-22 1997-01-09 Ct Lab Farm Srl Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico.
IT1283782B1 (it) * 1996-08-09 1998-04-30 Ct Lab Farm Srl Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo
DK1140061T3 (da) * 1998-12-23 2003-08-25 Orphan Medical Inc Mikrobiologisk sunde og stabile opløsninger af gamma-hydroxybutyratsalt til behandling af narcolepsi
EP1316309A1 (en) * 1998-12-23 2003-06-04 Orphan Medical Inc. Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy
DE60019435T2 (de) * 1999-09-14 2006-02-23 Tepha, Inc., Cambridge Therapeutische anwendung von polymere die gamma-hydroxybutyrat enthalten
ITMI20020754A1 (it) * 2002-04-09 2003-10-09 Aboca S P A Composizioni effervescenti contenenti succhi di frutta essicati
CA2525132C (en) 2003-05-08 2011-06-28 Tepha, Inc. Polyhydroxyalkanoate medical textiles and fibers
ATE473021T1 (de) 2004-08-03 2010-07-15 Tepha Inc Nichtkräuselnde polyhydroxyalkanoatnähte
US7838556B2 (en) * 2006-02-21 2010-11-23 University Of Maryland, Baltimore Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands
CA2664985A1 (en) * 2006-09-29 2008-04-10 The Board Of Trustees Of The University Of Illinois Histone acetyl transferase activators and histone deacetylase inhibitors in the treatment of alcoholism
US7943683B2 (en) 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
US8778398B2 (en) 2008-11-04 2014-07-15 Jazz Pharmaceuticals, Inc. Immediate release formulations and dosage forms of gamma-hydroxybutyrate
US8771735B2 (en) 2008-11-04 2014-07-08 Jazz Pharmaceuticals, Inc. Immediate release dosage forms of sodium oxybate
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
MX2012011022A (es) 2010-03-24 2013-02-26 Jazz Pharmaceuticals Inc Formas de dosis de liberacion controlada para substancias de farmaco de alta dosis, solubles en agua e higroscopicas.
MX340591B (es) * 2010-05-04 2016-07-15 Jazz Pharmaceuticals Inc * Formulaciones de liberacion inmediata y formas de dosis de gamma-hidroxibutirato.
US8591922B1 (en) 2012-12-14 2013-11-26 Jazz Pharmacuticals, Inc. Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
US9050302B2 (en) 2013-03-01 2015-06-09 Jazz Pharmaceuticals Ireland Limited Method of administration of gamma hydroxybutyrate with monocarboxylate transporters
ES2807178T3 (es) 2014-08-15 2021-02-22 Tepha Inc Suturas de autorretención de poli-4-hidroxibutirato y copolímeros del mismo
US9555155B2 (en) 2014-12-11 2017-01-31 Tepha, Inc. Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
US10398662B1 (en) 2015-02-18 2019-09-03 Jazz Pharma Ireland Limited GHB formulation and method for its manufacture
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602513B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US20180263936A1 (en) 2017-03-17 2018-09-20 Jazz Pharmaceuticals Ireland Limited Gamma-hydroxybutyrate compositions and their use for the treatment of disorders
KR20210094513A (ko) 2018-11-19 2021-07-29 재즈 파마슈티칼즈 아일랜드 리미티드 알코올-내성 약물 제형
US11400065B2 (en) 2019-03-01 2022-08-02 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044801B1 (de) * 1980-07-17 1984-02-15 Josef Dr. Klosa Nichthygroskopische Salze der 4-Hydroxybuttersäure, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Mittel

Also Published As

Publication number Publication date
PT90732A (pt) 1989-12-29
IT8820859A0 (it) 1988-06-03
GR3018009T3 (en) 1996-02-29
FI892718A0 (fi) 1989-06-02
AU633002B2 (en) 1993-01-21
IT1217783B (it) 1990-03-30
ATE126433T1 (de) 1995-09-15
DE68923819T2 (de) 1996-01-18
FI892718A (fi) 1989-12-04
AU3590489A (en) 1989-12-07
DE68923819D1 (de) 1995-09-21
NO892270D0 (no) 1989-06-02
CA1330423C (en) 1994-06-28
DK272389A (da) 1989-12-04
EP0344704A1 (en) 1989-12-06
ZA894128B (en) 1990-03-28
DK272389D0 (da) 1989-06-02
US4983632A (en) 1991-01-08
PT90732B (pt) 1994-10-31
DK174017B1 (da) 2002-04-15
NO892270L (no) 1989-12-04
EP0344704B1 (en) 1995-08-16
NZ229399A (en) 1997-02-24
AR241512A1 (es) 1992-08-31

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