DK168761B1 - Phenylethere og farmaceutisk acceptable salte deraf, fremgangsmåder til fremstilling heraf samt far maceutiske midler indeholdelde disse - Google Patents
Phenylethere og farmaceutisk acceptable salte deraf, fremgangsmåder til fremstilling heraf samt far maceutiske midler indeholdelde disse Download PDFInfo
- Publication number
- DK168761B1 DK168761B1 DK359986A DK359986A DK168761B1 DK 168761 B1 DK168761 B1 DK 168761B1 DK 359986 A DK359986 A DK 359986A DK 359986 A DK359986 A DK 359986A DK 168761 B1 DK168761 B1 DK 168761B1
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- hydrogen
- amino
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8519154 | 1985-07-30 | ||
GB858519154A GB8519154D0 (en) | 1985-07-30 | 1985-07-30 | Aromatic ethers |
Publications (3)
Publication Number | Publication Date |
---|---|
DK359986D0 DK359986D0 (da) | 1986-07-29 |
DK359986A DK359986A (da) | 1987-01-31 |
DK168761B1 true DK168761B1 (da) | 1994-06-06 |
Family
ID=10583042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK359986A DK168761B1 (da) | 1985-07-30 | 1986-07-29 | Phenylethere og farmaceutisk acceptable salte deraf, fremgangsmåder til fremstilling heraf samt far maceutiske midler indeholdelde disse |
Country Status (27)
Country | Link |
---|---|
US (1) | US4772631A (xx) |
EP (1) | EP0210849B1 (xx) |
JP (2) | JPH0651661B2 (xx) |
KR (1) | KR870001142A (xx) |
CN (1) | CN1014516B (xx) |
AR (1) | AR242176A1 (xx) |
AT (1) | ATE55980T1 (xx) |
AU (1) | AU603987B2 (xx) |
CA (1) | CA1283122C (xx) |
CS (1) | CS266593B2 (xx) |
DD (1) | DD251551A5 (xx) |
DE (1) | DE3673722D1 (xx) |
DK (1) | DK168761B1 (xx) |
ES (1) | ES2002720A6 (xx) |
FI (1) | FI88030C (xx) |
GB (1) | GB8519154D0 (xx) |
GR (1) | GR861994B (xx) |
HU (1) | HUT44757A (xx) |
IE (1) | IE60157B1 (xx) |
IL (1) | IL79447A0 (xx) |
NO (1) | NO170480C (xx) |
NZ (1) | NZ217011A (xx) |
PH (1) | PH22503A (xx) |
PL (1) | PL152320B1 (xx) |
PT (1) | PT83085B (xx) |
SU (1) | SU1632370A3 (xx) |
ZA (1) | ZA865097B (xx) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0300290B1 (de) * | 1987-07-21 | 1991-12-18 | F. Hoffmann-La Roche Ag | Phenoxypropanolamine |
GB8801306D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Chemical compounds |
GB8905336D0 (en) * | 1989-03-08 | 1989-04-19 | Ici Plc | Chemical compounds |
GB8910374D0 (en) * | 1989-05-05 | 1989-06-21 | Ici Plc | Chemical compounds |
KR920005952B1 (ko) * | 1989-05-26 | 1992-07-25 | 이사무 이와이 | 오수정화조의 여과재 순환 정화장치 |
GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
GB8926083D0 (en) * | 1989-11-17 | 1990-01-10 | Ici Plc | Therapeutic agents |
GB9003185D0 (en) * | 1990-02-13 | 1990-04-11 | Ici Plc | Pharmaceutical compositions |
US5245053A (en) * | 1990-05-04 | 1993-09-14 | American Cyanamid Company | Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles |
US5151439A (en) * | 1990-05-04 | 1992-09-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
US5061727A (en) | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
GB9016655D0 (en) * | 1990-07-30 | 1990-09-12 | Ici Plc | Therapeutic agents |
US5502078A (en) * | 1991-05-28 | 1996-03-26 | Zeneca Limited | Chemical compounds |
GB9111426D0 (en) * | 1991-05-28 | 1991-07-17 | Ici Plc | Chemical compounds |
GB9111425D0 (en) * | 1991-05-28 | 1991-07-17 | Ici Plc | Chemical compounds |
GB9224740D0 (en) * | 1992-11-26 | 1993-01-13 | Ici Plc | Therapeutic agents |
US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
US5776983A (en) * | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
US5488064A (en) * | 1994-05-02 | 1996-01-30 | Bristol-Myers Squibb Company | Benzo 1,3 dioxole derivatives |
US5491134A (en) * | 1994-09-16 | 1996-02-13 | Bristol-Myers Squibb Company | Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives |
US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
US6075040A (en) * | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
US5770615A (en) * | 1996-04-04 | 1998-06-23 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
EP0827746B1 (en) | 1996-09-05 | 2002-04-03 | Eli Lilly And Company | Carbazole analogues as selective beta3 adrenergic agonists |
CO5011072A1 (es) | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
GB9812709D0 (en) | 1998-06-13 | 1998-08-12 | Glaxo Group Ltd | Chemical compounds |
US6344481B1 (en) | 1999-03-01 | 2002-02-05 | Pfizer Inc. | Thyromimetic antiobesity agents |
US7504435B2 (en) * | 2001-01-31 | 2009-03-17 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method for stimulating weight loss and/or for lowering triglycerides in patients |
US7709677B2 (en) * | 2001-01-31 | 2010-05-04 | Glaxosmithkline Llc | Process of preparing arylethanoldiamines |
GB0102407D0 (en) | 2001-01-31 | 2001-03-14 | Glaxo Group Ltd | Process |
US7202222B2 (en) * | 2003-01-06 | 2007-04-10 | National Bioscience Corporation | Methods for treatment of obesity and effective fat loss promotion |
WO2008106213A1 (en) * | 2007-02-27 | 2008-09-04 | Titan Pharmaceuticals, Inc. | Administration of 3,5-diiodothyropropionic acid for stimulating weight loss, and/or lowering triglyceride levels, and/or treatment of metabolic syndrome. |
US8476227B2 (en) | 2010-01-22 | 2013-07-02 | Ethicon Endo-Surgery, Inc. | Methods of activating a melanocortin-4 receptor pathway in obese subjects |
US9044606B2 (en) | 2010-01-22 | 2015-06-02 | Ethicon Endo-Surgery, Inc. | Methods and devices for activating brown adipose tissue using electrical energy |
US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
US9522129B2 (en) | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
US9394233B2 (en) * | 2012-03-01 | 2016-07-19 | Cincinnati Children's Hospital Medical Center | ROS-activated compounds as selective anti-cancer therapeutics |
CN107205964A (zh) | 2014-12-03 | 2017-09-26 | 威力塞帕特治疗股份有限公司 | 使用调节释放索拉贝隆用于下尿路症状的组合物和方法 |
US10092738B2 (en) | 2014-12-29 | 2018-10-09 | Ethicon Llc | Methods and devices for inhibiting nerves when activating brown adipose tissue |
US10080884B2 (en) | 2014-12-29 | 2018-09-25 | Ethicon Llc | Methods and devices for activating brown adipose tissue using electrical energy |
US10065922B2 (en) | 2015-10-23 | 2018-09-04 | Velicept Therapeutics, Inc. | Solabegron zwitterion and uses thereof |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1957706C3 (de) * | 1968-11-18 | 1978-06-29 | Pfizer Corp., Colon (Panama) | Kernsubstituierte 3-Phenoxy-l-phenoxyalkylamino-propan-2-ole und Arzneimittel auf deren Basis |
GB1245148A (en) * | 1968-11-18 | 1971-09-08 | Pfizer Ltd | Propanolamine derivatives |
SE354851B (xx) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
US4191765A (en) * | 1976-05-25 | 1980-03-04 | Hoechst Aktiengesellschaft | 1-Aryloxy-2-hydroxy-3-aminopropanes |
CH632987A5 (en) * | 1976-10-07 | 1982-11-15 | Haessle Ab | Process for preparing novel amines |
SE416545B (sv) * | 1976-10-07 | 1981-01-19 | Haessle Ab | Forfarande for framstellning av nya hjertaktiva 1-frnoxi-3-aminopropan-2-ol-derivat |
DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
SE7807408L (sv) * | 1978-06-30 | 1979-12-31 | Haessle Ab | Hjertaktiva foreningar |
ATE1994T1 (de) * | 1979-06-16 | 1982-12-15 | Beecham Group Plc | Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen. |
EP0028105B1 (en) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
IL65541A0 (en) * | 1981-05-06 | 1982-07-30 | Haessle Ab | Alkylamino-2-propanols,process for their preparation and pharmaceutical preparations containing same |
GB8415377D0 (en) * | 1984-06-15 | 1984-07-18 | Beecham Group Plc | Compounds |
GB8510146D0 (en) * | 1985-04-20 | 1985-05-30 | Smith Kline French Lab | Chemical compounds & processes |
-
1985
- 1985-07-30 GB GB858519154A patent/GB8519154D0/en active Pending
-
1986
- 1986-07-07 IE IE182786A patent/IE60157B1/en not_active IP Right Cessation
- 1986-07-08 ZA ZA865097A patent/ZA865097B/xx unknown
- 1986-07-09 PH PH33996A patent/PH22503A/en unknown
- 1986-07-09 FI FI862896A patent/FI88030C/fi not_active IP Right Cessation
- 1986-07-10 AU AU60029/86A patent/AU603987B2/en not_active Ceased
- 1986-07-17 IL IL79447A patent/IL79447A0/xx not_active IP Right Cessation
- 1986-07-23 PL PL1986260759A patent/PL152320B1/pl unknown
- 1986-07-25 EP EP86305749A patent/EP0210849B1/en not_active Expired - Lifetime
- 1986-07-25 DE DE8686305749T patent/DE3673722D1/de not_active Expired - Lifetime
- 1986-07-25 AT AT86305749T patent/ATE55980T1/de not_active IP Right Cessation
- 1986-07-28 US US06/889,857 patent/US4772631A/en not_active Expired - Lifetime
- 1986-07-28 HU HU863206A patent/HUT44757A/hu unknown
- 1986-07-29 SU SU864027877A patent/SU1632370A3/ru active
- 1986-07-29 NO NO863061A patent/NO170480C/no unknown
- 1986-07-29 DD DD86293056A patent/DD251551A5/de not_active IP Right Cessation
- 1986-07-29 NZ NZ217011A patent/NZ217011A/en unknown
- 1986-07-29 DK DK359986A patent/DK168761B1/da not_active IP Right Cessation
- 1986-07-29 GR GR861994A patent/GR861994B/el unknown
- 1986-07-29 PT PT83085A patent/PT83085B/pt unknown
- 1986-07-29 CA CA000514820A patent/CA1283122C/en not_active Expired - Lifetime
- 1986-07-30 CS CS865735A patent/CS266593B2/cs unknown
- 1986-07-30 CN CN86105400A patent/CN1014516B/zh not_active Expired
- 1986-07-30 KR KR1019860006278A patent/KR870001142A/ko not_active Application Discontinuation
- 1986-07-30 JP JP61177914A patent/JPH0651661B2/ja not_active Expired - Lifetime
- 1986-07-30 AR AR86304733A patent/AR242176A1/es active
- 1986-07-30 ES ES8600729A patent/ES2002720A6/es not_active Expired
-
1993
- 1993-12-24 JP JP5327984A patent/JPH0819062B2/ja not_active Ceased
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |