DK168213B1 - Alkoxymethylether- og alkoxymethylesterderivater af glycerol og fremgangsmåde til fremstilling af 9-(1,3-dihydroxy-2-propoxymethyl)guanin og ethere og estere deraf - Google Patents

Alkoxymethylether- og alkoxymethylesterderivater af glycerol og fremgangsmåde til fremstilling af 9-(1,3-dihydroxy-2-propoxymethyl)guanin og ethere og estere deraf Download PDF

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Publication number
DK168213B1
DK168213B1 DK574085A DK574085A DK168213B1 DK 168213 B1 DK168213 B1 DK 168213B1 DK 574085 A DK574085 A DK 574085A DK 574085 A DK574085 A DK 574085A DK 168213 B1 DK168213 B1 DK 168213B1
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Prior art keywords
optionally substituted
lower alkyl
compound
guanine
phenyl
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DK574085A
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Danish (da)
English (en)
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DK574085D0 (da
DK574085A (da
Inventor
Jr David John Morgans
Harlan Hanford Chapman
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Syntex Inc
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Publication of DK574085A publication Critical patent/DK574085A/da
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/14Preparation of carboxylic acid esters from carboxylic acid halides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/24Preparation of carboxylic acid esters by reacting carboxylic acids or derivatives thereof with a carbon-to-oxygen ether bond, e.g. acetal, tetrahydrofuran
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/28Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/12Acetic acid esters
    • C07C69/14Acetic acid esters of monohydroxylic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/24Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/28Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with dihydroxylic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/30Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/753Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK574085A 1984-12-12 1985-12-11 Alkoxymethylether- og alkoxymethylesterderivater af glycerol og fremgangsmåde til fremstilling af 9-(1,3-dihydroxy-2-propoxymethyl)guanin og ethere og estere deraf DK168213B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68103784A 1984-12-12 1984-12-12
US68103784 1984-12-12
US79538185A 1985-11-12 1985-11-12
US79538185 1985-11-12

Publications (3)

Publication Number Publication Date
DK574085D0 DK574085D0 (da) 1985-12-11
DK574085A DK574085A (da) 1986-06-13
DK168213B1 true DK168213B1 (da) 1994-02-28

Family

ID=27102577

Family Applications (3)

Application Number Title Priority Date Filing Date
DK574085A DK168213B1 (da) 1984-12-12 1985-12-11 Alkoxymethylether- og alkoxymethylesterderivater af glycerol og fremgangsmåde til fremstilling af 9-(1,3-dihydroxy-2-propoxymethyl)guanin og ethere og estere deraf
DK038493A DK170233B1 (da) 1984-12-12 1993-03-31 Fremgangsmåde til fremstilling af alkoxymethylether- og alkoxymethylesterderivater af glyceroler
DK199300385A DK173252B1 (da) 1984-12-12 1993-03-31 Alkoxymethylethere af glyceroler

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK038493A DK170233B1 (da) 1984-12-12 1993-03-31 Fremgangsmåde til fremstilling af alkoxymethylether- og alkoxymethylesterderivater af glyceroler
DK199300385A DK173252B1 (da) 1984-12-12 1993-03-31 Alkoxymethylethere af glyceroler

Country Status (15)

Country Link
EP (1) EP0187297B1 (no)
JP (2) JPH075595B2 (no)
KR (1) KR910000198B1 (no)
AU (1) AU598185B2 (no)
CA (1) CA1330797C (no)
DE (1) DE3583858D1 (no)
DK (3) DK168213B1 (no)
ES (4) ES8705889A1 (no)
FI (1) FI91959C (no)
HK (1) HK167996A (no)
HU (1) HUT39145A (no)
IE (1) IE58569B1 (no)
IL (1) IL77298A (no)
NO (1) NO172183C (no)
NZ (1) NZ214520A (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds
JPS63150245A (ja) * 1986-12-12 1988-06-22 Idemitsu Kosan Co Ltd カルボン酸エステルの製造方法
GB8724765D0 (en) * 1987-10-22 1987-11-25 Beecham Group Plc Process
US4855239A (en) * 1987-12-28 1989-08-08 Environmental Test Systems, Inc. Test composition and device for the determination of cyanuric acid in water
US5068119A (en) * 1990-09-28 1991-11-26 Nabisco Brands, Inc. Acid-hydrolyzable ester derivatives as low calorie fat mimetics
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
US5840891A (en) * 1994-07-28 1998-11-24 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5852208A (en) * 1996-08-30 1998-12-22 Dixie Chemical Company, Inc. Method of producing compounds containing acyloxyalkoxy groups from alcohols
US10087043B2 (en) 2014-09-10 2018-10-02 Hewlett-Packard Development Company, L.P. Moving media in reverse duplex direction along media duplex path

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59407A (en) * 1979-03-06 1983-12-30 Sanofi Sa Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives

Also Published As

Publication number Publication date
EP0187297B1 (en) 1991-08-21
ES8801274A1 (es) 1988-01-01
NO854968L (no) 1986-06-13
KR910000198B1 (ko) 1991-01-23
HK167996A (en) 1996-09-13
JP2559565B2 (ja) 1996-12-04
DK38493A (da) 1993-03-31
FI854879A (fi) 1986-06-13
ES555508A0 (es) 1987-07-01
ES8706603A1 (es) 1987-07-01
DK170233B1 (da) 1995-07-10
IE853127L (en) 1986-06-12
DE3583858D1 (de) 1991-09-26
NZ214520A (en) 1989-08-29
IE58569B1 (en) 1993-10-06
AU5118785A (en) 1986-07-17
KR860004831A (ko) 1986-07-14
AU598185B2 (en) 1990-06-21
DK38593A (da) 1993-03-31
FI854879A0 (fi) 1985-12-11
HUT39145A (en) 1986-08-28
CA1330797C (en) 1994-07-19
JPH075595B2 (ja) 1995-01-25
DK574085D0 (da) 1985-12-11
DK173252B1 (da) 2000-05-22
ES549840A0 (es) 1987-06-01
NO172183B (no) 1993-03-08
ES8706602A1 (es) 1987-07-01
DK38493D0 (da) 1993-03-31
JPS61155346A (ja) 1986-07-15
DK38593D0 (da) 1993-03-31
FI91959C (fi) 1994-09-12
EP0187297A2 (en) 1986-07-16
EP0187297A3 (en) 1987-07-01
ES8705889A1 (es) 1987-06-01
FI91959B (fi) 1994-05-31
JPH0753463A (ja) 1995-02-28
DK574085A (da) 1986-06-13
IL77298A (en) 1999-11-30
ES555507A0 (es) 1987-07-01
ES555509A0 (es) 1988-01-01
NO172183C (no) 1993-06-16

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B1 Patent granted (law 1993)
PUP Patent expired