DK167531B1 - Pyrrolidinon- og oxazolidinonderivater og deres anvendelse til fremstilling af farmaceutiske praeparater - Google Patents
Pyrrolidinon- og oxazolidinonderivater og deres anvendelse til fremstilling af farmaceutiske praeparater Download PDFInfo
- Publication number
- DK167531B1 DK167531B1 DK288686A DK288686A DK167531B1 DK 167531 B1 DK167531 B1 DK 167531B1 DK 288686 A DK288686 A DK 288686A DK 288686 A DK288686 A DK 288686A DK 167531 B1 DK167531 B1 DK 167531B1
- Authority
- DK
- Denmark
- Prior art keywords
- oxazolidinone
- methyl
- methoxyphenyl
- mmol
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B1/00—Engines characterised by fuel-air mixture compression
- F02B1/02—Engines characterised by fuel-air mixture compression with positive ignition
- F02B1/04—Engines characterised by fuel-air mixture compression with positive ignition with fuel-air mixture admission into cylinder
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3438839 | 1984-10-19 | ||
DE19843438839 DE3438839A1 (de) | 1984-10-19 | 1984-10-19 | Pharmazeutische praeparate |
DE8500472 | 1985-10-18 | ||
PCT/DE1985/000472 WO1986002268A1 (en) | 1984-10-19 | 1985-10-18 | Pharmaceutical preparations |
Publications (3)
Publication Number | Publication Date |
---|---|
DK288686D0 DK288686D0 (da) | 1986-06-19 |
DK288686A DK288686A (da) | 1986-06-19 |
DK167531B1 true DK167531B1 (da) | 1993-11-15 |
Family
ID=6248597
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK288686A DK167531B1 (da) | 1984-10-19 | 1986-06-19 | Pyrrolidinon- og oxazolidinonderivater og deres anvendelse til fremstilling af farmaceutiske praeparater |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0198919B1 (no) |
JP (2) | JPH0742229B2 (no) |
AU (2) | AU5095885A (no) |
DE (2) | DE3438839A1 (no) |
DK (1) | DK167531B1 (no) |
FI (1) | FI862590A0 (no) |
NO (1) | NO164897C (no) |
WO (1) | WO1986002268A1 (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5783591A (en) * | 1984-10-19 | 1998-07-21 | Schering Aktiengesellschaft | Administration of oxazolidinone and pyrolidinone compounds for the treatment of inflammation |
US4681940A (en) * | 1985-11-19 | 1987-07-21 | American Home Products Corporation | 5-[3-[[2-quinolyl]methoxy]phenyl]-1,3-oxazoles |
DE3639225A1 (de) * | 1986-11-14 | 1988-05-19 | Schering Ag | Verwendung von 5-(subst. phenyl)-oxazolidinonderiaten als psychopharmaka |
US4968707A (en) * | 1987-06-10 | 1990-11-06 | Pfizer Inc. | Oxazolidin-2-one derivatives as hypoglycemic agents |
ES2057110T3 (es) * | 1988-03-24 | 1994-10-16 | Sankyo Co | Utilizacion de isoxazolinonas como farmacos con accion sobre el cerebro. |
WO1992002220A1 (en) * | 1990-08-03 | 1992-02-20 | Smithkline Beecham Corporation | Tnf inhibitors |
US5124455A (en) * | 1990-08-08 | 1992-06-23 | American Home Products Corporation | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents |
US5547979A (en) * | 1992-03-30 | 1996-08-20 | Smithkline Beecham | TNF inhibition |
WO1996024350A1 (de) * | 1995-02-10 | 1996-08-15 | Schering Aktiengesellschaft | Pharmazeutische präparate zur tnf-inhibition |
DE19540475A1 (de) * | 1995-10-20 | 1997-04-24 | Schering Ag | Chirale Methylphenyloxazolidinone |
US6770658B2 (en) * | 1998-09-09 | 2004-08-03 | Inflazyme Pharmaceuticals Ltd. | Substituted γ-phenyl-Δ-lactams and uses related thereto |
DE60233884D1 (de) * | 2001-10-16 | 2009-11-12 | Memory Pharmaceutical Corp | 4(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidon-derivate als pde-4-hemmer zur behandlung von neurologischen syndromen |
WO2004098592A1 (ja) * | 2003-05-06 | 2004-11-18 | Senju Pharmaceutical Co. Ltd. | オキサゾリジノン誘導体含有組成物 |
AR057218A1 (es) | 2005-12-15 | 2007-11-21 | Astra Ab | Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2413935A1 (de) * | 1974-03-20 | 1975-10-16 | Schering Ag | 4-(polyalkoxy-phenyl)-2-pyrrolidone |
SU888821A3 (ru) * | 1976-12-03 | 1981-12-07 | Шеринг Аг (Инофирма) | Способ получени 5-(замещенный фенил)-оксазолидинонов или их серусодержащих аналогов |
DE2655369A1 (de) * | 1976-12-03 | 1978-06-08 | Schering Ag | 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung |
-
1984
- 1984-10-19 DE DE19843438839 patent/DE3438839A1/de not_active Withdrawn
-
1985
- 1985-10-18 AU AU50958/85A patent/AU5095885A/en not_active Abandoned
- 1985-10-18 JP JP60505152A patent/JPH0742229B2/ja not_active Expired - Lifetime
- 1985-10-18 DE DE8585905773T patent/DE3576118D1/de not_active Expired - Lifetime
- 1985-10-18 WO PCT/DE1985/000472 patent/WO1986002268A1/de active IP Right Grant
- 1985-10-18 EP EP85905773A patent/EP0198919B1/de not_active Expired - Lifetime
-
1986
- 1986-06-17 FI FI862590A patent/FI862590A0/fi not_active Application Discontinuation
- 1986-06-18 NO NO862439A patent/NO164897C/no unknown
- 1986-06-19 DK DK288686A patent/DK167531B1/da not_active IP Right Cessation
-
1990
- 1990-01-04 AU AU47653/90A patent/AU4765390A/en not_active Abandoned
-
1994
- 1994-02-04 JP JP6012897A patent/JP2669494B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0742229B2 (ja) | 1995-05-10 |
NO164897C (no) | 1990-11-28 |
JP2669494B2 (ja) | 1997-10-27 |
EP0198919A1 (de) | 1986-10-29 |
NO862439L (no) | 1986-06-18 |
WO1986002268A1 (en) | 1986-04-24 |
JPS62501289A (ja) | 1987-05-21 |
DE3576118D1 (de) | 1990-04-05 |
DK288686D0 (da) | 1986-06-19 |
AU4765390A (en) | 1990-05-03 |
NO164897B (no) | 1990-08-20 |
JPH0761978A (ja) | 1995-03-07 |
EP0198919B1 (de) | 1990-02-28 |
DE3438839A1 (de) | 1986-04-24 |
AU5095885A (en) | 1986-05-02 |
FI862590A (fi) | 1986-06-17 |
FI862590A0 (fi) | 1986-06-17 |
DK288686A (da) | 1986-06-19 |
NO862439D0 (no) | 1986-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |