DK165790C - Fremgangsmaade til fremstilling af adriamycin-4'-o-derivater eller syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af adriamycin-4'-o-derivater eller syreadditionssalte derafInfo
- Publication number
- DK165790C DK165790C DK184481A DK184481A DK165790C DK 165790 C DK165790 C DK 165790C DK 184481 A DK184481 A DK 184481A DK 184481 A DK184481 A DK 184481A DK 165790 C DK165790 C DK 165790C
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- procedure
- acid addition
- addition salts
- adriamycin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5597480 | 1980-04-26 | ||
JP5597480A JPS56156300A (en) | 1980-04-26 | 1980-04-26 | Novel preparative method of anthracyclin derivative |
Publications (3)
Publication Number | Publication Date |
---|---|
DK184481A DK184481A (da) | 1981-10-27 |
DK165790B DK165790B (da) | 1993-01-18 |
DK165790C true DK165790C (da) | 1993-06-14 |
Family
ID=13014042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK184481A DK165790C (da) | 1980-04-26 | 1981-04-24 | Fremgangsmaade til fremstilling af adriamycin-4'-o-derivater eller syreadditionssalte deraf |
Country Status (7)
Country | Link |
---|---|
US (1) | US4360664A (da) |
EP (1) | EP0039060B1 (da) |
JP (1) | JPS56156300A (da) |
CA (1) | CA1157016A (da) |
DE (1) | DE3175057D1 (da) |
DK (1) | DK165790C (da) |
ES (1) | ES8202833A1 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6016998A (ja) * | 1983-07-07 | 1985-01-28 | Microbial Chem Res Found | アントラサイクリン誘導体の製造方法 |
JPS61502956A (ja) * | 1984-06-14 | 1986-12-18 | ビオガル ジヨジセルジヤ−ル | アドリアマイシン及びそのハロゲン化塩の調整法 |
JPS62116591A (ja) * | 1985-11-16 | 1987-05-28 | Microbial Chem Res Found | 4′−O−テトラヒドロピラニルアドリアマイシンbの製造方法 |
US4889926A (en) * | 1987-06-12 | 1989-12-26 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Method for the synthesis of (2"R)-4'-O-tetra-hydropyranyladriamycim using 14-chloro-daunomycin as an intermediate |
US4997922A (en) * | 1988-09-06 | 1991-03-05 | Sanraku Incorporated | Anthracycline derivatives |
IT1230505B (it) * | 1988-10-11 | 1991-10-25 | Sicor Spa | Procedimento per la conversione della daunorubicina in doxorubicina. |
GB9026491D0 (en) * | 1990-12-05 | 1991-01-23 | Erba Carlo Spa | Anthracycline-conjugates |
US5776458A (en) * | 1990-12-05 | 1998-07-07 | Pharmacia & Upjohn S.P.A. | Anthracycline-conjugates |
WO2004011033A1 (en) * | 2002-07-24 | 2004-02-05 | Universite Catholique De Louvain | Method for the synthesis of anthracycline-peptide conjugates |
CN103087124B (zh) * | 2012-11-21 | 2016-01-13 | 浙江海正药业股份有限公司 | 一种制备阿霉素的方法 |
CN108484689B (zh) * | 2018-03-06 | 2020-11-10 | 道中道(菏泽)制药有限公司 | 一种戊柔比星合成方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1527892A (fr) * | 1967-03-15 | 1968-06-07 | Rhone Poulenc Sa | Nouveau procédé de préparation de l'antibiotique 13057 r.p. |
YU33730B (en) * | 1967-04-18 | 1978-02-28 | Farmaceutici Italia | Process for preparing a novel antibiotic substance and salts thereof |
US3803124A (en) * | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
NL170737C (nl) * | 1975-11-12 | 1982-12-16 | Rhone Poulenc Ind | Werkwijze voor het bereiden van tegen tumoren werkzame esters van adriamycine, alsmede voor het bereiden van geneesmiddelen met anti-tumoractiviteit. |
GB1561507A (en) * | 1976-11-17 | 1980-02-20 | Farmaceutici Italia | Snthracycline disaccharides |
JPS5430146A (en) * | 1977-08-05 | 1979-03-06 | Microbial Chem Res Found | Novel anthracycline derivatives and their preparation |
DK160616C (da) * | 1979-02-03 | 1991-09-02 | Zaidan Hojin Biseibutsu | Fremgangsmaade til fremstilling af anthracyclinderivater eller syreadditionssalte deraf |
EP0022515B1 (en) * | 1979-07-04 | 1983-08-03 | FARMITALIA CARLO ERBA S.p.A. | Anthracycline glycosides, process for their preparation and therapeutical composition containing them |
-
1980
- 1980-04-26 JP JP5597480A patent/JPS56156300A/ja active Granted
-
1981
- 1981-04-13 US US06/253,489 patent/US4360664A/en not_active Expired - Fee Related
- 1981-04-16 CA CA000375761A patent/CA1157016A/en not_active Expired
- 1981-04-23 ES ES501572A patent/ES8202833A1/es not_active Expired
- 1981-04-24 EP EP81103104A patent/EP0039060B1/en not_active Expired
- 1981-04-24 DE DE8181103104T patent/DE3175057D1/de not_active Expired
- 1981-04-24 DK DK184481A patent/DK165790C/da active
Also Published As
Publication number | Publication date |
---|---|
ES501572A0 (es) | 1982-02-16 |
DK165790B (da) | 1993-01-18 |
ES8202833A1 (es) | 1982-02-16 |
JPS6259719B2 (da) | 1987-12-12 |
CA1157016A (en) | 1983-11-15 |
US4360664A (en) | 1982-11-23 |
EP0039060A1 (en) | 1981-11-04 |
DK184481A (da) | 1981-10-27 |
JPS56156300A (en) | 1981-12-02 |
DE3175057D1 (en) | 1986-09-11 |
EP0039060B1 (en) | 1986-08-06 |
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