DK1646391T3 - Anvendelse af 2H-[1,3]-oxazino[3,2-A]indolderivater til behandling af neuropatisk smerte - Google Patents

Anvendelse af 2H-[1,3]-oxazino[3,2-A]indolderivater til behandling af neuropatisk smerte

Info

Publication number
DK1646391T3
DK1646391T3 DK04740899T DK04740899T DK1646391T3 DK 1646391 T3 DK1646391 T3 DK 1646391T3 DK 04740899 T DK04740899 T DK 04740899T DK 04740899 T DK04740899 T DK 04740899T DK 1646391 T3 DK1646391 T3 DK 1646391T3
Authority
DK
Denmark
Prior art keywords
oxazino
treatment
neuropathic pain
indole derivatives
indole
Prior art date
Application number
DK04740899T
Other languages
English (en)
Inventor
Lorenzo Polenzani
Angelo Guglielmotti
Alessandra Alisi
Nicola Cazzolla
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of DK1646391T3 publication Critical patent/DK1646391T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK04740899T 2003-07-18 2004-07-08 Anvendelse af 2H-[1,3]-oxazino[3,2-A]indolderivater til behandling af neuropatisk smerte DK1646391T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001467A ITMI20031467A1 (it) 2003-07-18 2003-07-18 Farmaco attivo nel dolore neuropatico
PCT/EP2004/007633 WO2005014001A1 (en) 2003-07-18 2004-07-08 Use of 2h- [1, 3] - oxazino [3, 2-a] indole derivatives for the treatment of neuropathic pain

Publications (1)

Publication Number Publication Date
DK1646391T3 true DK1646391T3 (da) 2007-03-19

Family

ID=34131193

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04740899T DK1646391T3 (da) 2003-07-18 2004-07-08 Anvendelse af 2H-[1,3]-oxazino[3,2-A]indolderivater til behandling af neuropatisk smerte

Country Status (21)

Country Link
US (1) US20060211691A1 (da)
EP (1) EP1646391B1 (da)
JP (1) JP2006528142A (da)
KR (1) KR20060033784A (da)
CN (1) CN100409850C (da)
AR (1) AR045993A1 (da)
AT (1) ATE345137T1 (da)
AU (1) AU2004262876B2 (da)
CA (1) CA2526852C (da)
DE (1) DE602004003252T2 (da)
DK (1) DK1646391T3 (da)
EA (1) EA008927B1 (da)
ES (1) ES2276317T3 (da)
GE (1) GEP20084307B (da)
HK (1) HK1087027A1 (da)
IL (1) IL172156A0 (da)
IT (1) ITMI20031467A1 (da)
PL (1) PL1646391T3 (da)
PT (1) PT1646391E (da)
UA (1) UA81050C2 (da)
WO (1) WO2005014001A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101563075B (zh) * 2006-12-26 2011-09-28 大鹏药品工业株式会社 糖尿病性神经病治疗剂
DE102007058504A1 (de) 2007-12-05 2009-07-09 Acino Ag Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189041A (en) * 1990-11-16 1993-02-23 Syntex (U.S.A.) Inc. Tricyclic 5-ht3 receptor antagonists
GB9120628D0 (en) * 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
HU219121B (hu) * 1992-03-12 2001-02-28 Smithkline Beecham Plc. Kondenzált indolszármazékok, eljárás előállításukra és ezeket tartalmazó 5-HT4-receptor antagonista hatású gyógyászati készítmények
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
JP2003506388A (ja) * 1999-08-04 2003-02-18 アイカゲン インコーポレイテッド 疼痛および不安症を処置または予防するための方法
US20040038874A1 (en) * 2002-08-22 2004-02-26 Osemwota Omoigui Method of treatment of persistent pain

Also Published As

Publication number Publication date
US20060211691A1 (en) 2006-09-21
ATE345137T1 (de) 2006-12-15
EA008927B1 (ru) 2007-08-31
HK1087027A1 (en) 2006-10-06
KR20060033784A (ko) 2006-04-19
AU2004262876B2 (en) 2010-05-20
JP2006528142A (ja) 2006-12-14
EA200600270A1 (ru) 2006-06-30
ITMI20031467A1 (it) 2005-01-19
IL172156A0 (en) 2006-04-10
EP1646391A1 (en) 2006-04-19
CN100409850C (zh) 2008-08-13
PT1646391E (pt) 2007-01-31
CN1809361A (zh) 2006-07-26
AU2004262876A1 (en) 2005-02-17
UA81050C2 (en) 2007-11-26
DE602004003252T2 (de) 2007-05-03
ES2276317T3 (es) 2007-06-16
CA2526852C (en) 2011-08-30
PL1646391T3 (pl) 2007-04-30
GEP20084307B (en) 2008-02-11
DE602004003252D1 (de) 2006-12-28
WO2005014001A1 (en) 2005-02-17
EP1646391B1 (en) 2006-11-15
CA2526852A1 (en) 2005-02-17
AR045993A1 (es) 2005-11-23
WO2005014001A9 (en) 2005-05-26

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