DK1635875T3 - In-situ-geldannende lægemiddeladministrationssystem - Google Patents
In-situ-geldannende lægemiddeladministrationssystemInfo
- Publication number
- DK1635875T3 DK1635875T3 DK04756068T DK04756068T DK1635875T3 DK 1635875 T3 DK1635875 T3 DK 1635875T3 DK 04756068 T DK04756068 T DK 04756068T DK 04756068 T DK04756068 T DK 04756068T DK 1635875 T3 DK1635875 T3 DK 1635875T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug administration
- administration system
- situ gelling
- gelling drug
- situ
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Nanotechnology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48267703P | 2003-06-26 | 2003-06-26 | |
US57530704P | 2004-05-28 | 2004-05-28 | |
PCT/US2004/020369 WO2005002625A2 (en) | 2003-06-26 | 2004-06-25 | In-situ gelling drug delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1635875T3 true DK1635875T3 (da) | 2009-01-12 |
Family
ID=33567657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04756068T DK1635875T3 (da) | 2003-06-26 | 2004-06-25 | In-situ-geldannende lægemiddeladministrationssystem |
Country Status (16)
Country | Link |
---|---|
US (4) | US20050048123A1 (zh) |
EP (2) | EP2044959A1 (zh) |
JP (1) | JP5229768B2 (zh) |
CN (2) | CN1863557B (zh) |
AR (1) | AR044926A1 (zh) |
AT (1) | ATE410186T1 (zh) |
CA (1) | CA2530136C (zh) |
CY (1) | CY1108685T1 (zh) |
DE (1) | DE602004016995D1 (zh) |
DK (1) | DK1635875T3 (zh) |
ES (1) | ES2315680T3 (zh) |
PL (1) | PL1635875T3 (zh) |
PT (1) | PT1635875E (zh) |
SI (1) | SI1635875T1 (zh) |
TW (1) | TWI377958B (zh) |
WO (1) | WO2005002625A2 (zh) |
Families Citing this family (40)
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WO2004027027A2 (en) | 2002-09-18 | 2004-04-01 | Trustees Of The University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
CN1882338A (zh) * | 2003-09-18 | 2006-12-20 | 马库赛特公司 | 经巩膜递送 |
US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
WO2006086744A1 (en) | 2005-02-09 | 2006-08-17 | Macusight, Inc. | Formulations for ocular treatment |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
BRPI0707612B8 (pt) | 2006-02-09 | 2021-05-25 | Macusight Inc | vaso lacrado e formulações líquidas contidas no mesmo |
JP5506378B2 (ja) | 2006-03-23 | 2014-05-28 | 参天製薬株式会社 | 血管透過性に関連する疾患または病気のための製剤および方法 |
JP4827626B2 (ja) * | 2006-06-14 | 2011-11-30 | キヤノン株式会社 | 被制御機器、遠隔制御システムおよび遠隔制御システムの制御方法、プログラム |
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US20110059921A1 (en) * | 2008-03-27 | 2011-03-10 | Ektar Therapeutics | Oligomer-Nitrogenous Base Conjugates |
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GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
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EP3215223B1 (en) | 2014-11-07 | 2020-07-01 | Indivior UK Limited | Buprenorphine dosing regimens |
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US10525034B2 (en) | 2014-12-15 | 2020-01-07 | The Johns Hopkins University | Sunitinib formulations and methods for use thereof in treatment of glaucoma |
ES2960753T3 (es) | 2015-09-21 | 2024-03-06 | Teva Pharmaceuticals Int Gmbh | Formulaciones de olanzapina de liberación sostenida |
TWI641387B (zh) * | 2015-10-29 | 2018-11-21 | 逸達生物科技股份有限公司 | 安定性經改善之醫藥組成物 |
CN108367079B (zh) | 2015-11-12 | 2022-11-22 | 灰色视觉公司 | 用于治疗的聚集性微粒 |
CN110691605A (zh) * | 2017-03-14 | 2020-01-14 | 费城儿童医院 | 用于基于纳米载体的癌症治疗的可裂解酯 |
JP2020511483A (ja) | 2017-03-20 | 2020-04-16 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH | 徐放性オランザピン製剤 |
MX2019011242A (es) | 2017-03-23 | 2020-01-21 | Graybug Vision Inc | Farmacos y composiciones para el tratamiento de trastornos oculares. |
BR112019022908A2 (pt) | 2017-05-10 | 2020-05-26 | Graybug Vision, Inc. | Micropartícula de agregação sólida, sólido liofilizado ou reconstituível de micropartículas de agregação, método para tratamento de um distúrbio ocular, e, uso das micropartículas de agregação sólidas |
WO2018227187A1 (en) * | 2017-06-09 | 2018-12-13 | The Regents Of The University Of California | Catheter injectable cyclic peptide pro-gelators for myocardial tissue engineering |
US11167034B2 (en) | 2017-06-13 | 2021-11-09 | The University Of British Columbia | Polymeric paste compositions for drug delivery |
US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
US20220040201A1 (en) * | 2018-09-25 | 2022-02-10 | Tolmar International, Ltd. | Liquid polymer delivery system for extended administration of drugs |
CN111374940A (zh) * | 2020-04-13 | 2020-07-07 | 宁波赛缪斯生物科技有限公司 | 一种可原位聚合的胶原注射剂及其使用方法 |
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EP4366726A1 (en) | 2021-07-06 | 2024-05-15 | Mark Hasleton | Treatment of serotonin reuptake inhibitor withdrawal syndrome |
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US20030049320A1 (en) * | 2000-12-18 | 2003-03-13 | Wockhardt Limited | Novel in-situ forming controlled release microcarrier delivery system |
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-
2004
- 2004-06-25 CA CA2530136A patent/CA2530136C/en not_active Expired - Fee Related
- 2004-06-25 DK DK04756068T patent/DK1635875T3/da active
- 2004-06-25 AR ARP040102252A patent/AR044926A1/es not_active Application Discontinuation
- 2004-06-25 PT PT04756068T patent/PT1635875E/pt unknown
- 2004-06-25 DE DE602004016995T patent/DE602004016995D1/de active Active
- 2004-06-25 WO PCT/US2004/020369 patent/WO2005002625A2/en active Application Filing
- 2004-06-25 EP EP08017574A patent/EP2044959A1/en not_active Withdrawn
- 2004-06-25 US US10/877,758 patent/US20050048123A1/en not_active Abandoned
- 2004-06-25 TW TW093118700A patent/TWI377958B/zh not_active IP Right Cessation
- 2004-06-25 SI SI200430994T patent/SI1635875T1/sl unknown
- 2004-06-25 EP EP04756068A patent/EP1635875B8/en not_active Not-in-force
- 2004-06-25 CN CN2004800237331A patent/CN1863557B/zh not_active Expired - Fee Related
- 2004-06-25 CN CN201010165296A patent/CN101862455A/zh active Pending
- 2004-06-25 JP JP2006517646A patent/JP5229768B2/ja not_active Expired - Fee Related
- 2004-06-25 PL PL04756068T patent/PL1635875T3/pl unknown
- 2004-06-25 ES ES04756068T patent/ES2315680T3/es active Active
- 2004-06-25 AT AT04756068T patent/ATE410186T1/de active
-
2008
- 2008-12-19 CY CY20081101469T patent/CY1108685T1/el unknown
-
2010
- 2010-08-27 US US12/870,616 patent/US20110165242A1/en not_active Abandoned
-
2012
- 2012-09-12 US US13/612,076 patent/US20130101656A1/en not_active Abandoned
-
2014
- 2014-07-28 US US14/444,338 patent/US9566336B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN1863557A (zh) | 2006-11-15 |
ES2315680T3 (es) | 2009-04-01 |
US20130101656A1 (en) | 2013-04-25 |
CN1863557B (zh) | 2010-06-16 |
SI1635875T1 (sl) | 2009-04-30 |
CA2530136A1 (en) | 2005-01-13 |
CY1108685T1 (el) | 2014-04-09 |
EP1635875B1 (en) | 2008-10-08 |
JP5229768B2 (ja) | 2013-07-03 |
DE602004016995D1 (de) | 2008-11-20 |
PT1635875E (pt) | 2008-12-09 |
WO2005002625A3 (en) | 2005-04-21 |
PL1635875T3 (pl) | 2009-03-31 |
US20050048123A1 (en) | 2005-03-03 |
CA2530136C (en) | 2012-10-16 |
EP2044959A1 (en) | 2009-04-08 |
ATE410186T1 (de) | 2008-10-15 |
US9566336B2 (en) | 2017-02-14 |
TW200514581A (en) | 2005-05-01 |
EP1635875A2 (en) | 2006-03-22 |
TWI377958B (en) | 2012-12-01 |
CN101862455A (zh) | 2010-10-20 |
US20140336278A1 (en) | 2014-11-13 |
AR044926A1 (es) | 2005-10-12 |
EP1635875B8 (en) | 2008-12-24 |
JP2007524628A (ja) | 2007-08-30 |
WO2005002625A2 (en) | 2005-01-13 |
US20110165242A1 (en) | 2011-07-07 |
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