DK1631275T3 - Behandling og forebyggelse af excessiv ardannelse med 4-hydroxy-tamoxifen - Google Patents

Behandling og forebyggelse af excessiv ardannelse med 4-hydroxy-tamoxifen

Info

Publication number
DK1631275T3
DK1631275T3 DK04740032T DK04740032T DK1631275T3 DK 1631275 T3 DK1631275 T3 DK 1631275T3 DK 04740032 T DK04740032 T DK 04740032T DK 04740032 T DK04740032 T DK 04740032T DK 1631275 T3 DK1631275 T3 DK 1631275T3
Authority
DK
Denmark
Prior art keywords
excessive scarring
tamoxifen
hydroxy
prevention
treatment
Prior art date
Application number
DK04740032T
Other languages
English (en)
Inventor
Andrew R Palumbo
Julius Few
Dana C Hilt
Original Assignee
Ascend Therapeutics Inc
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ascend Therapeutics Inc, Univ Northwestern filed Critical Ascend Therapeutics Inc
Application granted granted Critical
Publication of DK1631275T3 publication Critical patent/DK1631275T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK04740032T 2003-06-09 2004-06-02 Behandling og forebyggelse af excessiv ardannelse med 4-hydroxy-tamoxifen DK1631275T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47661803P 2003-06-09 2003-06-09
PCT/EP2004/006583 WO2004110420A1 (en) 2003-06-09 2004-06-02 Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen

Publications (1)

Publication Number Publication Date
DK1631275T3 true DK1631275T3 (da) 2008-08-18

Family

ID=33551623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04740032T DK1631275T3 (da) 2003-06-09 2004-06-02 Behandling og forebyggelse af excessiv ardannelse med 4-hydroxy-tamoxifen

Country Status (13)

Country Link
US (1) US7767717B2 (da)
EP (1) EP1631275B1 (da)
JP (1) JP4682129B2 (da)
AT (1) ATE393625T1 (da)
AU (1) AU2004246812B8 (da)
CA (1) CA2528431C (da)
DE (1) DE602004013439T2 (da)
DK (1) DK1631275T3 (da)
ES (1) ES2304610T3 (da)
HK (1) HK1082203A1 (da)
NZ (1) NZ544031A (da)
PT (1) PT1631275E (da)
WO (1) WO2004110420A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003294973B2 (en) * 2002-12-18 2010-05-13 Besins Healthcare Luxembourg Sarl Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
DE60327363D1 (de) 2002-12-18 2009-06-04 Besins Int Lab Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen
AU2003303033B2 (en) * 2002-12-18 2009-06-04 Besins Healthcare Luxembourg Sarl Treatment of mastalgia with 4-hydroxy tamoxifen
DK1694319T3 (da) * 2003-12-15 2008-11-17 Besins Int Lab Anvendelser af 4-hydroxytamoxifen til fremstilling af et medikament til behandling af gynækomasti
US7968532B2 (en) 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579857A1 (en) * 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
EP1647271A1 (en) * 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations
EP1891945A1 (en) * 2006-07-31 2008-02-27 Laboratoires Besins International Treatment and prevention of excessive scarring
CA2659344C (en) * 2006-07-31 2015-03-17 Laboratoires Besins International Treatment and prevention of excessive scarring
US20130184220A1 (en) * 2007-12-21 2013-07-18 Bradford James Duft Treatment of abnormal or excessive scars
AU2008343758A1 (en) * 2007-12-21 2009-07-09 Coda Therapeutics, Inc. Use of anti-connexin 43 polynucleotides for the treatment of abnormal or excessive scars
US20140350117A1 (en) * 2013-05-22 2014-11-27 Professional Compounding Centers Of America Topical Scar Treatment Composition and Method of Using Same
US20140350106A1 (en) * 2013-05-22 2014-11-27 Professional Compounding Centers Of America Urea Silicone Gel for Scars and Hydration Treatment and Method of Using Same
CA3074440A1 (en) * 2017-09-01 2019-03-07 Excel Med, Llc Pharmaceutical composition for treating keloid and uses thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
ATE80152T1 (de) 1987-04-21 1992-09-15 Heumann Pharma Gmbh & Co Stabile loesungsmitteladdukte von z-1-(p-betadimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl) 2-phenylbut-1-en.
US5045553A (en) 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
DE3836862A1 (de) 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
WO1991001624A2 (en) * 1989-07-31 1991-02-21 Massachusetts Institute Of Technology Use of calcium antagonists for treating scars
TW218849B (da) 1991-05-17 1994-01-11 Bristol Myers Squibb Co
DE69334068D1 (de) 1992-07-20 2006-11-16 Massachusetts Inst Technology Kontrolle der wundvernarbung mit calmodulin-inhibitoren oder protein-kinase-c-inhibitoren
US5552162A (en) 1993-02-09 1996-09-03 Arch Development Corporation Method for improvement of scar size and appearance
US5613958A (en) 1993-05-12 1997-03-25 Pp Holdings Inc. Transdermal delivery systems for the modulated administration of drugs
US5720963A (en) 1994-08-26 1998-02-24 Mary Kay Inc. Barrier disruption treatments for structurally deteriorated skin
JP2001527037A (ja) * 1997-12-23 2001-12-25 ヘキサル アーゲー Z−4−ヒドロキシタモキシフェン及びシクロデキストリンを含む混合物及び薬剤学的組成
US6013270A (en) 1998-04-20 2000-01-11 The Procter & Gamble Company Skin care kit
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
ES2330188T3 (es) 2001-12-07 2009-12-07 Besins Manufacturing Belgium Composicion farmaceutica en forma de gel o de solucion a base de dihidrotestoterona, su procedimiento de preparacion y sus utilizaciones.
AU2003303033B2 (en) 2002-12-18 2009-06-04 Besins Healthcare Luxembourg Sarl Treatment of mastalgia with 4-hydroxy tamoxifen
AU2003294973B2 (en) 2002-12-18 2010-05-13 Besins Healthcare Luxembourg Sarl Prevention and treatment of breast cancer with 4-hydroxy tamoxifen
DE60327363D1 (de) 2002-12-18 2009-06-04 Besins Int Lab Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen
US7968532B2 (en) 2003-12-15 2011-06-28 Besins Healthcare Luxembourg Treatment of gynecomastia with 4-hydroxy tamoxifen
EP1579856A1 (en) 2004-03-22 2005-09-28 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
US7507769B2 (en) 2004-03-22 2009-03-24 Laboratoires Besins International Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
EP1579857A1 (en) 2004-03-22 2005-09-28 Laboratoires Besins International Chemically stable compositions of 4-hydroxy tamoxifen
EP1647271A1 (en) 2004-10-14 2006-04-19 Laboratoires Besins International 4-Hydroxy tamoxifen gel formulations

Also Published As

Publication number Publication date
ES2304610T3 (es) 2008-10-16
HK1082203A1 (en) 2006-06-02
CA2528431C (en) 2012-09-18
CA2528431A1 (en) 2004-12-23
WO2004110420A8 (en) 2005-11-24
EP1631275A1 (en) 2006-03-08
AU2004246812A1 (en) 2004-12-23
DE602004013439T2 (de) 2009-06-04
US7767717B2 (en) 2010-08-03
EP1631275B1 (en) 2008-04-30
AU2004246812B2 (en) 2009-12-17
AU2004246812B8 (en) 2010-01-14
DE602004013439D1 (de) 2008-06-12
WO2004110420A1 (en) 2004-12-23
US20050032910A1 (en) 2005-02-10
NZ544031A (en) 2008-08-29
JP4682129B2 (ja) 2011-05-11
PT1631275E (pt) 2008-08-04
JP2006527234A (ja) 2006-11-30
ATE393625T1 (de) 2008-05-15

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