DE60326348D1 - Makrozyclen zur behandlung von krebserkrankungen - Google Patents
Makrozyclen zur behandlung von krebserkrankungenInfo
- Publication number
- DE60326348D1 DE60326348D1 DE60326348T DE60326348T DE60326348D1 DE 60326348 D1 DE60326348 D1 DE 60326348D1 DE 60326348 T DE60326348 T DE 60326348T DE 60326348 T DE60326348 T DE 60326348T DE 60326348 D1 DE60326348 D1 DE 60326348D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- macrocles
- cancer disorders
- cancer
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/04—Ortho-condensed systems
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10232094A DE10232094A1 (de) | 2002-07-15 | 2002-07-15 | 5-Thiaepothilone und 15-disubstituierte Epothilone |
| DE10255660A DE10255660A1 (de) | 2002-11-28 | 2002-11-28 | Neue Makrocyclen zur Behandlung von Krebserkrankungen |
| PCT/EP2003/007664 WO2004007492A1 (de) | 2002-07-15 | 2003-07-15 | A taper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60326348D1 true DE60326348D1 (de) | 2009-04-09 |
Family
ID=30116646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60326348T Expired - Lifetime DE60326348D1 (de) | 2002-07-15 | 2003-07-15 | Makrozyclen zur behandlung von krebserkrankungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7553859B2 (de) |
| EP (1) | EP1521752B1 (de) |
| JP (1) | JP4597667B2 (de) |
| AT (1) | ATE423780T1 (de) |
| AU (1) | AU2003252540B2 (de) |
| CA (1) | CA2491943C (de) |
| DE (1) | DE60326348D1 (de) |
| DK (1) | DK1521752T3 (de) |
| ES (1) | ES2323956T3 (de) |
| WO (1) | WO2004007492A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2330517T3 (es) * | 2002-11-28 | 2009-12-11 | Wolfgang Richter | Derivados de tia-epotilona para el tratamiento del cancer. |
| CN102076339A (zh) | 2008-04-24 | 2011-05-25 | 百时美施贵宝公司 | 埃坡霉素D在治疗包括阿尔茨海默病的τ相关疾病中的用途 |
| EP2394640A1 (de) | 2010-05-21 | 2011-12-14 | MediGene AG | Verbesserte liposomale Formulierungen von lipophilen Verbindungen |
| EP2708243A1 (de) | 2012-09-17 | 2014-03-19 | OntoChem GmbH | Rezeptor-Ligand-verbundene zytotoxische Moleküle |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001243372A1 (en) * | 2000-03-01 | 2001-09-12 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| WO2002000216A1 (en) * | 2000-06-28 | 2002-01-03 | Teva Pharmaceutical Industries Ltd. | Carvedilol |
| ES2330517T3 (es) * | 2002-11-28 | 2009-12-11 | Wolfgang Richter | Derivados de tia-epotilona para el tratamiento del cancer. |
-
2003
- 2003-07-15 JP JP2004520647A patent/JP4597667B2/ja not_active Expired - Fee Related
- 2003-07-15 AT AT03763870T patent/ATE423780T1/de not_active IP Right Cessation
- 2003-07-15 US US10/520,769 patent/US7553859B2/en not_active Expired - Fee Related
- 2003-07-15 WO PCT/EP2003/007664 patent/WO2004007492A1/de active Application Filing
- 2003-07-15 EP EP03763870A patent/EP1521752B1/de not_active Expired - Lifetime
- 2003-07-15 DK DK03763870T patent/DK1521752T3/da active
- 2003-07-15 DE DE60326348T patent/DE60326348D1/de not_active Expired - Lifetime
- 2003-07-15 CA CA2491943A patent/CA2491943C/en not_active Expired - Fee Related
- 2003-07-15 AU AU2003252540A patent/AU2003252540B2/en not_active Ceased
- 2003-07-15 ES ES03763870T patent/ES2323956T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1521752A1 (de) | 2005-04-13 |
| AU2003252540A1 (en) | 2004-02-02 |
| US7553859B2 (en) | 2009-06-30 |
| AU2003252540B2 (en) | 2008-11-20 |
| CA2491943C (en) | 2012-06-19 |
| ES2323956T3 (es) | 2009-07-28 |
| CA2491943A1 (en) | 2004-01-22 |
| JP2005537263A (ja) | 2005-12-08 |
| DK1521752T3 (da) | 2009-06-22 |
| JP4597667B2 (ja) | 2010-12-15 |
| WO2004007492A1 (de) | 2004-01-22 |
| US20060004065A1 (en) | 2006-01-05 |
| EP1521752B1 (de) | 2009-02-25 |
| ATE423780T1 (de) | 2009-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMB, DE Owner name: RICHTER, WOLFGANG, DR., 81243 MUENCHEN, DE |
|
| 8364 | No opposition during term of opposition |