DK162646C - 3-(4-benzyl-piperazin-1-yl)-rifamycin sv- og s-forbindelser samt salte deraf, fremgangsmaade til fremstilling deraf og farmaceutiske sammensaetninger indeholdende disse forbindelser - Google Patents

3-(4-benzyl-piperazin-1-yl)-rifamycin sv- og s-forbindelser samt salte deraf, fremgangsmaade til fremstilling deraf og farmaceutiske sammensaetninger indeholdende disse forbindelser

Info

Publication number
DK162646C
DK162646C DK307587A DK307587A DK162646C DK 162646 C DK162646 C DK 162646C DK 307587 A DK307587 A DK 307587A DK 307587 A DK307587 A DK 307587A DK 162646 C DK162646 C DK 162646C
Authority
DK
Denmark
Prior art keywords
compounds
rifamycin
piperazin
salts
benzyl
Prior art date
Application number
DK307587A
Other languages
Danish (da)
English (en)
Other versions
DK307587D0 (da
DK162646B (da
DK307587A (da
Inventor
Wilhelm Kump
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK307587D0 publication Critical patent/DK307587D0/da
Publication of DK307587A publication Critical patent/DK307587A/da
Publication of DK162646B publication Critical patent/DK162646B/da
Application granted granted Critical
Publication of DK162646C publication Critical patent/DK162646C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK307587A 1985-10-18 1987-06-17 3-(4-benzyl-piperazin-1-yl)-rifamycin sv- og s-forbindelser samt salte deraf, fremgangsmaade til fremstilling deraf og farmaceutiske sammensaetninger indeholdende disse forbindelser DK162646C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH8500155 1985-10-18
PCT/CH1985/000155 WO1987002361A1 (en) 1985-10-18 1985-10-18 Substituted 4-benzyl-piperazinyl compounds

Publications (4)

Publication Number Publication Date
DK307587D0 DK307587D0 (da) 1987-06-17
DK307587A DK307587A (da) 1987-06-17
DK162646B DK162646B (da) 1991-11-25
DK162646C true DK162646C (da) 1992-04-13

Family

ID=4542209

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307587A DK162646C (da) 1985-10-18 1987-06-17 3-(4-benzyl-piperazin-1-yl)-rifamycin sv- og s-forbindelser samt salte deraf, fremgangsmaade til fremstilling deraf og farmaceutiske sammensaetninger indeholdende disse forbindelser

Country Status (13)

Country Link
US (1) US4918066A (xx)
EP (1) EP0244398B1 (xx)
JP (1) JPS63501712A (xx)
KR (1) KR870700626A (xx)
AT (1) ATE47857T1 (xx)
DE (1) DE3574142D1 (xx)
DK (1) DK162646C (xx)
FI (1) FI85486C (xx)
HU (1) HUT47586A (xx)
MC (1) MC1819A1 (xx)
MW (1) MW3687A1 (xx)
NO (1) NO169073C (xx)
WO (1) WO1987002361A1 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4876258A (en) * 1987-08-13 1989-10-24 Ciba-Geigy Corporation Biphenylyl compounds
EP0308568A1 (de) * 1987-09-25 1989-03-29 Ciba-Geigy Ag Diacylderivate von 4-( Trialkylbenzyl)-piperazinyl-Verbindungen
US4916126A (en) * 1987-09-25 1990-04-10 Ciba-Geigy Corporation Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds
GB8725118D0 (en) * 1987-10-27 1987-12-02 Ciba Geigy Ag Rifamycin derivatives
AU624088B2 (en) * 1987-10-27 1992-06-04 Ciba-Geigy Ag Substituted azacyclohexyl derivatives
HU203893B (en) * 1987-10-27 1991-10-28 Ciba Geigy Ag Process for producing substituted 3-piperazinyl-1-deoxy-15-deoxo-1,15-epoxy- -rifamycin derivatives and pharmaceutical compositions containing them
EP0350445A1 (de) * 1988-06-30 1990-01-10 Ciba-Geigy Ag Substituierte Azacyclohexyl-Derivate
US5180718A (en) * 1989-03-02 1993-01-19 Ciba-Geigy Corporation Acyl derivatives of oxazolorifamycins
HU204835B (en) * 1989-04-26 1992-02-28 Ciba Geigy Ag New process for producing rifamycin compounds
EP0475895A1 (en) * 1990-08-31 1992-03-18 Ciba-Geigy Ag Acyl derivatives of rifamycins and their use as medicaments
EP0475896A1 (en) * 1990-08-31 1992-03-18 Ciba-Geigy Ag Polycyclic compounds
US7087420B1 (en) 1997-07-17 2006-08-08 Cambia Microbial β-glucuronidase genes, gene products and uses thereof
US6391547B1 (en) * 1997-09-09 2002-05-21 Center For The Application Of Molecular Biology To International Agriculture Microbial β-glucuronidase genes, gene products and uses thereof
BG64021B1 (bg) * 1998-11-04 2003-10-31 КОНСТАНТИНОВА Румяна Натриева сол на 3-(4-цинамил-1-пиперазинил)-иминометил рифамицин и метод за получаването й
CA2881958C (en) * 2012-08-13 2019-08-27 Adipharm Ead Pharmaceutical formulations containing 3-(4-cinnamyl-1-piperazinyl) amino derivatives of 3-formylrifamycin sv and 3-formylrifamycin s and a process of their preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR208F (xx) * 1964-07-31
US4005077A (en) * 1965-08-24 1977-01-25 Ciba-Geigy Corporation Antibiotically active compounds
IT1046627B (it) * 1970-06-01 1980-07-31 Lepetit Spa Composizioni antivirali contenenti derivati della rifaumicina sv
GB1486118A (en) * 1975-03-05 1977-09-21 Lepetit Spa Rifamycin derivatives
GB1478563A (en) * 1975-03-05 1977-07-06 Lepetit Spa Rifamycin derivatives
GR64108B (en) * 1977-04-15 1980-01-24 Dso Pharmachim Method for the preparation of azomethine-derivatives of rifamycin s.v
US4551450A (en) * 1984-08-27 1985-11-05 Ciba-Geigy Corporation Rifamycin hydrazones, pharmaceutical compositions containing them and their use
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis

Also Published As

Publication number Publication date
DK307587D0 (da) 1987-06-17
US4918066A (en) 1990-04-17
EP0244398A1 (de) 1987-11-11
FI85486C (fi) 1992-04-27
DE3574142D1 (en) 1989-12-14
FI872636A0 (fi) 1987-06-12
MC1819A1 (fr) 1988-03-18
NO872409D0 (no) 1987-06-09
WO1987002361A1 (en) 1987-04-23
KR870700626A (ko) 1987-12-30
ATE47857T1 (de) 1989-11-15
NO169073B (no) 1992-01-27
NO872409L (no) 1987-06-09
HUT47586A (en) 1989-03-28
NO169073C (no) 1992-05-06
JPS63501712A (ja) 1988-07-14
FI872636A (fi) 1987-06-12
JPH0236597B2 (xx) 1990-08-17
FI85486B (fi) 1992-01-15
DK162646B (da) 1991-11-25
EP0244398B1 (de) 1989-11-08
DK307587A (da) 1987-06-17
MW3687A1 (en) 1988-09-14

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Legal Events

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PBP Patent lapsed