DK1562954T3 - CCR1-antagonister til behandling af I.A. inflammatorisk demyelinisationssygdom - Google Patents

CCR1-antagonister til behandling af I.A. inflammatorisk demyelinisationssygdom

Info

Publication number: DK1562954T3
Authority: DK; Denmark
Prior art keywords: treatment; inflammatory demyelination; ccr1 antagonists; demyelination disease; disease
Prior art date: 2002-11-13

Application number

DK03768852T

Other languages

English (en)

Inventor

Kenneth G Carson

Geraldine C B Harriman

Shomir Ghosh

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-13

Filing date

2003-11-12

Publication date

2006-08-28

2003-11-12 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2006-08-28 Application granted granted Critical

2006-08-28 Publication of DK1562954T3 publication Critical patent/DK1562954T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK03768852T 2002-11-13 2003-11-12 CCR1-antagonister til behandling af I.A. inflammatorisk demyelinisationssygdom DK1562954T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US42594702P	2002-11-13	2002-11-13

Publications (1)

Publication Number	Publication Date
DK1562954T3 true DK1562954T3 (da)	2006-08-28

Family

ID=32313083

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03768852T DK1562954T3 (da)	2002-11-13	2003-11-12	CCR1-antagonister til behandling af I.A. inflammatorisk demyelinisationssygdom

Country Status (25)

Country	Link
US (7)	US20040106639A1 (da)
EP (2)	EP1562954B1 (da)
JP (1)	JP4644491B2 (da)
KR (1)	KR101109348B1 (da)
CN (1)	CN100343257C (da)
AR (1)	AR041942A1 (da)
AT (2)	ATE468340T1 (da)
AU (2)	AU2003291452A1 (da)
BR (1)	BR0316261A (da)
CA (1)	CA2505874C (da)
CY (1)	CY1107985T1 (da)
DE (2)	DE60332663D1 (da)
DK (1)	DK1562954T3 (da)
EA (1)	EA007748B1 (da)
ES (2)	ES2261979T3 (da)
HK (2)	HK1074046A1 (da)
IL (2)	IL168384A (da)
MX (1)	MXPA05005105A (da)
NO (1)	NO331855B1 (da)
PL (1)	PL211022B1 (da)
PT (1)	PT1562954E (da)
SI (1)	SI1562954T1 (da)
TW (1)	TWI291467B (da)
WO (1)	WO2004043965A1 (da)
ZA (2)	ZA200504144B (da)

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TWI291467B (en)	2002-11-13	2007-12-21	Millennium Pharm Inc	CCR1 antagonists and methods of use therefor
US7838522B2 (en)	2004-11-17	2010-11-23	Ares Trading S.A.	Benzothiazole formulations and use thereof
CN101119725B (zh)	2004-12-17	2013-04-17	千禧药品公司	化学趋化因子受体拮抗剂的固体形式和其使用方法
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KR20080044836A (ko)	2005-07-15	2008-05-21	라보라뚜와르 세로노 에스. 에이.	자궁내막증 치료용 ｊｎｋ 억제제
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KR101237296B1 (ko)	2008-01-11	2013-03-04	일라이 릴리 앤드 캄파니	류마티스성 관절염의 치료를 위한 글루코코르티코이드 수용체 조절제로서의 (Ｅ)-Ｎ-｛3-［1-（8-플루오로-11Ｈ-10-옥사-1-아자-디벤조［ａ,ｄ］시클로헵텐-5-일리덴）-프로필］-페닐｝-메탄술폰아미드
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2003
- 2003-11-11 TW TW92131488A patent/TWI291467B/zh not_active IP Right Cessation
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- 2003-11-12 CA CA 2505874 patent/CA2505874C/en not_active Expired - Fee Related
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2006
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2007
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Also Published As

Publication number	Publication date
CN1738824A (zh)	2006-02-22
EP1562954B1 (en)	2006-05-03
ES2261979T3 (es)	2006-11-16
WO2004043965A1 (en)	2004-05-27
EP1669356A1 (en)	2006-06-14
SI1562954T1 (sl)	2006-10-31
AU2003291452A1 (en)	2004-06-03
ZA200504144B (en)	2007-04-25
EP1562954A1 (en)	2005-08-17
PL377715A1 (pl)	2006-02-06
US20130289063A1 (en)	2013-10-31
US7977350B2 (en)	2011-07-12
HK1086011A1 (en)	2006-09-08
KR101109348B1 (ko)	2012-01-31
IL210046A0 (en)	2011-07-31
US20050288319A1 (en)	2005-12-29
DE60305063D1 (de)	2006-06-08
BR0316261A (pt)	2005-10-11
US7732459B2 (en)	2010-06-08
AU2008202965B2 (en)	2012-03-22
PL211022B1 (pl)	2012-03-30
NO20052272L (no)	2005-06-06
JP2006508966A (ja)	2006-03-16
US20110230516A1 (en)	2011-09-22
HK1074046A1 (en)	2005-10-28
CA2505874A1 (en)	2004-05-27
JP4644491B2 (ja)	2011-03-02
IL168384A (en)	2011-01-31
US20080139602A1 (en)	2008-06-12
MXPA05005105A (es)	2005-07-01
DE60305063T2 (de)	2006-11-16
US20150005338A1 (en)	2015-01-01
AU2008202965A1 (en)	2008-07-31
TWI291467B (en)	2007-12-21
CY1107985T1 (el)	2013-09-04
US9334283B2 (en)	2016-05-10
PT1562954E (pt)	2006-07-31
ATE325124T1 (de)	2006-06-15
EA007748B1 (ru)	2006-12-29
TW200413347A (en)	2004-08-01
ZA200607868B (en)	2008-01-08
CN100343257C (zh)	2007-10-17
AR041942A1 (es)	2005-06-01
IL210046A (en)	2015-07-30
DE60332663D1 (de)	2010-07-01
EP1669356B1 (en)	2010-05-19
US8394817B2 (en)	2013-03-12
US20040106639A1 (en)	2004-06-03
EA200500803A1 (ru)	2005-10-27
KR20050074609A (ko)	2005-07-18
US20100249174A1 (en)	2010-09-30
CA2505874C (en)	2012-07-17
ES2346337T3 (es)	2010-10-14
NO331855B1 (no)	2012-04-23
ATE468340T1 (de)	2010-06-15

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