DK154382A - Hidtil ukendte derivater af 2-piperazinopyrimidin,fremgangsmaader til deres fremstilling og deres anvendelse som laegemidlereller mellemprodukter til fremstilling af laegemidler - Google Patents
Hidtil ukendte derivater af 2-piperazinopyrimidin,fremgangsmaader til deres fremstilling og deres anvendelse som laegemidlereller mellemprodukter til fremstilling af laegemidler Download PDFInfo
- Publication number
- DK154382A DK154382A DK154382A DK154382A DK154382A DK 154382 A DK154382 A DK 154382A DK 154382 A DK154382 A DK 154382A DK 154382 A DK154382 A DK 154382A DK 154382 A DK154382 A DK 154382A
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- medicinal
- medicinal products
- piperazinopyrimidine
- procedures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8106924 | 1981-04-07 | ||
FR8106924A FR2503162A1 (fr) | 1981-04-07 | 1981-04-07 | Nouveaux derives de piperazino-2 pyrimidine, procedes pour leur preparation et leur utilisation comme medicaments ou comme intermediaires pour la fabrication de medicaments |
Publications (3)
Publication Number | Publication Date |
---|---|
DK154382A true DK154382A (da) | 1982-10-08 |
DK156722B DK156722B (da) | 1989-09-25 |
DK156722C DK156722C (da) | 1990-02-19 |
Family
ID=9257094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK154382A DK156722C (da) | 1981-04-07 | 1982-04-05 | Analogifremgangsmaade til fremstilling af 2-piperazinopyrimidinderivater |
Country Status (21)
Country | Link |
---|---|
US (1) | US4535080A (da) |
EP (1) | EP0063509B1 (da) |
JP (1) | JPS57179167A (da) |
AR (1) | AR231442A1 (da) |
AT (1) | AT386199B (da) |
AU (1) | AU549748B2 (da) |
CA (1) | CA1175427A (da) |
DE (1) | DE3262374D1 (da) |
DK (1) | DK156722C (da) |
ES (4) | ES8306745A1 (da) |
FI (1) | FI78909C (da) |
FR (1) | FR2503162A1 (da) |
GR (1) | GR77331B (da) |
HU (1) | HU187673B (da) |
IE (1) | IE52872B1 (da) |
IL (1) | IL65422A (da) |
MA (1) | MA19438A1 (da) |
MX (1) | MX156087A (da) |
NO (1) | NO158739C (da) |
PT (1) | PT74712B (da) |
ZA (1) | ZA822344B (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3305524A1 (de) * | 1983-02-18 | 1984-08-23 | Celamerck Gmbh & Co Kg, 6507 Ingelheim | Neue pyrimidinderivate |
DE3321969A1 (de) * | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
JPS6143173A (ja) * | 1984-08-06 | 1986-03-01 | Mitsui Petrochem Ind Ltd | 新規ピリミジン誘導体およびその製法 |
JP2561689B2 (ja) * | 1986-02-24 | 1996-12-11 | 三井石油化学工業株式会社 | 神経疾患用治療薬 |
DE3752141T2 (de) * | 1986-02-24 | 1998-03-26 | Mitsui Petrochemical Ind | Mittel zur behandlung von neuropathie |
WO1989000423A1 (en) | 1987-07-09 | 1989-01-26 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
US4910204A (en) * | 1988-06-28 | 1990-03-20 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
FI895821A0 (fi) * | 1988-12-07 | 1989-12-05 | Wellcome Found | Farmaceutiskt aktiva cns foereningar. |
EP1984390A2 (en) * | 2006-01-23 | 2008-10-29 | Board of Trustees of Michigan State University | Methods for breeding glyphosate resistant plants and compositions thereof |
TWI409265B (zh) * | 2008-08-20 | 2013-09-21 | Merck Sharp & Dohme | 經取代之吡啶及嘧啶衍生物及彼等於治療病毒感染之用途 |
CA2760911A1 (en) * | 2009-05-19 | 2010-11-25 | George E. Davis | Compounds and methods for controlling fungi |
CN103204816B (zh) * | 2012-01-16 | 2016-04-27 | 中国人民解放军军事医学科学院毒物药物研究所 | 哌嗪基嘧啶类衍生物及其制备方法和用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL72956C (da) * | 1947-11-12 | |||
FR2257294B1 (da) * | 1973-07-06 | 1977-07-01 | Ugine Kuhlmann | |
NL129219C (da) * | 1965-12-16 | |||
US3980781A (en) * | 1966-03-31 | 1976-09-14 | Imperial Chemical Industries Limited | Fungicidal composition and method containing 2-amino-pyrimidines |
FR2173746B1 (da) * | 1972-03-01 | 1975-04-25 | Ugine Kuhlmann | |
FR2244520B1 (da) * | 1973-07-06 | 1977-02-04 | Ugine Kuhlmann | |
JPS578104B2 (da) * | 1973-09-20 | 1982-02-15 | ||
GB1523274A (en) * | 1974-08-05 | 1978-08-31 | Ici Ltd | Herbicidal compositions containing substituted pyrimidine |
US4166852A (en) * | 1974-08-09 | 1979-09-04 | Produits Chimiques Ugine Kuhlmann | Piperazino-pyrimidines and their use as spasmolytic agents |
FR2281117A2 (fr) * | 1974-08-09 | 1976-03-05 | Ugine Kuhlmann | Nouvelles piperazino-pyrimidines utilisables comme medicaments |
FR2311776A1 (fr) * | 1975-05-23 | 1976-12-17 | Sogeras | Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation |
FR2417507A2 (fr) * | 1977-07-28 | 1979-09-14 | Ugine Kuhlmann | Diamino-2,4 (ou -4,6) methylthio-5 pyrimidines herbicides |
-
1981
- 1981-04-07 FR FR8106924A patent/FR2503162A1/fr active Granted
-
1982
- 1982-03-11 GR GR67575A patent/GR77331B/el unknown
- 1982-03-26 DE DE8282400551T patent/DE3262374D1/de not_active Expired
- 1982-03-26 EP EP82400551A patent/EP0063509B1/fr not_active Expired
- 1982-03-31 AT AT0127682A patent/AT386199B/de not_active IP Right Cessation
- 1982-04-01 MX MX192097A patent/MX156087A/es unknown
- 1982-04-01 IE IE774/82A patent/IE52872B1/en unknown
- 1982-04-05 MA MA19642A patent/MA19438A1/fr unknown
- 1982-04-05 AR AR289012A patent/AR231442A1/es active
- 1982-04-05 IL IL65422A patent/IL65422A/xx unknown
- 1982-04-05 DK DK154382A patent/DK156722C/da not_active IP Right Cessation
- 1982-04-05 ZA ZA822344A patent/ZA822344B/xx unknown
- 1982-04-06 ES ES511224A patent/ES8306745A1/es not_active Expired
- 1982-04-06 FI FI821203A patent/FI78909C/fi not_active IP Right Cessation
- 1982-04-06 JP JP57057179A patent/JPS57179167A/ja active Pending
- 1982-04-06 NO NO821159A patent/NO158739C/no unknown
- 1982-04-06 PT PT74712A patent/PT74712B/pt unknown
- 1982-04-07 CA CA000400630A patent/CA1175427A/fr not_active Expired
- 1982-04-07 HU HU821067A patent/HU187673B/hu not_active IP Right Cessation
- 1982-04-07 AU AU82450/82A patent/AU549748B2/en not_active Ceased
-
1983
- 1983-01-13 ES ES518974A patent/ES518974A0/es active Granted
- 1983-01-13 ES ES518975A patent/ES8400428A1/es not_active Expired
- 1983-01-13 ES ES518976A patent/ES518976A0/es active Granted
- 1983-08-24 US US06/525,799 patent/US4535080A/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK118791A (da) | 1-benzopyran-4-oner og 2-amino-1,3-benzoxazin-4-oner, deres fremstilling og anvendelse som eller til fremstilling af laegemidler | |
DK195587A (da) | Phenylpiperazinderivater og deres anvendelse til fremstilling af antiarrytmi-laegemidler | |
DK146482A (da) | Fremgangsmaade til fremstilling af cyklobutylaminderivater eller farmaceutisk acceptable salte deraf | |
DK189581A (da) | Hidtil ukendte heparinestere der er anvendelige til fremstilling af laegemidler og fremgangsmaader til deres frmstilling | |
DK408186D0 (da) | Podophyllotoxin og derivater deraf, fremgangsmaader til deres fremstilling og anvendelse samt farmaceutiske praeparater indeholdende forbindelserne | |
DK154382A (da) | Hidtil ukendte derivater af 2-piperazinopyrimidin,fremgangsmaader til deres fremstilling og deres anvendelse som laegemidlereller mellemprodukter til fremstilling af laegemidler | |
DK401180A (da) | Acylerede triazolyl-gamma-fluorpinacolylderivater fremgangsmaader til deres fremstilling og deres anvendelse som fungicider | |
DK445078A (da) | Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf | |
DK219685A (da) | Heterocycliske forbindelser, deres fremstilling og anvendelse som laegemidler | |
DK5379A (da) | 1-aza-(2,2,2)-bicyclooctanderivater mellemprodukter hertil og fremgangsmaade til deres fremstilling og deres anvendelse som laegemidler | |
DK48482A (da) | Azopigmentpraeparater,fremgangsmaade til deres fremstilling og deres anvendelse | |
DK165985C (da) | 1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler | |
DK489378A (da) | 6-oxygenerede-3,20-dioxopregnanderivater samt fremgangsmaade til fremstilling der af og farmaceutiske kompositioner indeholdende disse | |
DK162220C (da) | Tricykliske pyridazinderivater, som er agonister af cholinerge receptorer, fremgangsmaade til fremstilling af derivaterne, og laegemidler, hvori de er til stede | |
DK15282A (da) | Fremgangsmaade til fremstilling af (+)-enantiomere eller (+)(-)-racemiske 4a,9b-trans-hexahydro-1h-pyridoindol-derivater eller farmaceutisk acceptable syreadditionssalte deraf | |
DK364682A (da) | Substituerede azolylphenoxyderivater, deres fremstilling og anvendelse som fungicider | |
DK635988D0 (da) | 1,3-butandiolacetoacetat-derivater og anvendelse af 1,3-butandiolacetoacetat-forbindelser til fremstilling af farmaceutiske praeparater | |
DK258381A (da) | Hidtil ukendte indenderivater fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler | |
DK437287D0 (da) | 2,3-dihydrofuranderivater, deres fremstilling og deres anvendelse som mellemprodukter til fremstilling af tetrahydrofuranderivater | |
DK442183A (da) | Thiatriazin-derivater, fremgangsmaader til fremstilling deraf og deres anvendelse som laegemidler | |
DK506183A (da) | Hidtil ukendte carbacykliner, fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel | |
DK423284D0 (da) | Naphthalenylimidazopyridin og derivater heraf samt fremgangsmaade til fremstilling af saadanne forbindelser | |
DK161187A (da) | 5-phenyl-5h-indenooe1,2-daapyrimidin og derivater deraf samt fremgangsmaade til fremstilling af saadanneforbindelser. | |
DK511782A (da) | Benzylidenderivater, fremgangsmaade til deres fremstilling samt deres anvendelse | |
DK527180A (da) | Substituerede 2-amino-3,4-dihydropyridinderivater fremgangsmar ade til deres fremstilling og deres anvendelse som laegemidle |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed | ||
PBP | Patent lapsed |