US4929605A
(en)
*
|
1987-10-07 |
1990-05-29 |
Merrell Dow Pharmaceuticals Inc. |
Pharmaceutical composition for piperidinoalkanol derivatives
|
AR240018A1
(es)
*
|
1987-10-07 |
1990-01-31 |
Merrell Pharma Inc |
Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
|
CN1053570C
(zh)
|
1987-10-07 |
2000-06-21 |
默尔多药物公司 |
哌啶子基链烷醇的药用组合物-减充血剂复方的制备方法
|
US4908372A
(en)
*
|
1988-10-13 |
1990-03-13 |
Merrell Dow Pharmaceuticals Inc. |
Antihistaminic piperidinyl benzimidazoles
|
AR245888A1
(es)
*
|
1989-01-23 |
1994-03-30 |
Merrell Pharma Inc |
Procedimiento para la preparacion de una composicion farmaceutica liquida de derivados de piperidinoalcanol.
|
DE3917241A1
(de)
*
|
1989-05-26 |
1990-11-29 |
Schaper & Bruemmer Gmbh |
4-(hydroxydiphenylmethyl)-1-piperidyl-phenylalkan-derivate
|
US5190029A
(en)
*
|
1991-02-14 |
1993-03-02 |
Virginia Commonwealth University |
Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
|
US5182097A
(en)
*
|
1991-02-14 |
1993-01-26 |
Virginia Commonwealth University |
Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
|
TW198008B
(da)
*
|
1991-04-08 |
1993-01-11 |
Green Cross Corp |
|
HU211019B
(en)
*
|
1991-12-02 |
1995-09-28 |
Richter Gedeon Vegyeszet |
Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
|
HUT71097A
(en)
*
|
1992-02-13 |
1995-11-28 |
Merrell Dow Pharma |
Piperidinyl-heterocyclic derivatives, containing sulphur pharmaceutical compositions comprising them and process for their preparation
|
CA2117892C
(en)
*
|
1992-04-10 |
2001-12-18 |
Chi-Hsin R. King |
4-diphenylmethyl piperidine derivatives and process for their preparation
|
US5631375A
(en)
*
|
1992-04-10 |
1997-05-20 |
Merrell Pharmaceuticals, Inc. |
Process for piperidine derivatives
|
CA2134211C
(en)
*
|
1992-05-11 |
1999-06-29 |
James K. Woodward |
Use of terfenadine derivatives as antihistaminics in a hepatically impaired patient
|
EP0701443B2
(en)
*
|
1992-08-03 |
2000-11-22 |
Sepracor, Inc. |
Terfenadine metabolites and their optically pure isomers for treating allergic disorders
|
US5654433A
(en)
*
|
1993-01-26 |
1997-08-05 |
Merrell Pharmaceuticals Inc. |
Process for piperidine derivatives
|
DE69434696T2
(de)
*
|
1993-06-24 |
2006-11-16 |
Amr Technology, Inc. |
Verfahren zur Herstellung von Verbindungen geeignet als Zwischenprodukte
|
US20020007068A1
(en)
|
1999-07-16 |
2002-01-17 |
D'ambra Thomas E. |
Piperidine derivatives and process for their production
|
DE69431954T2
(de)
*
|
1993-06-25 |
2003-11-06 |
Merrell Pharmaceuticals Inc., Cincinnati |
Neue zwischenprodukte für die herstellung von antihistaminschen 4-diphenylmethyl/diphenylmethoxypiperidin-derivaten
|
US6147216A
(en)
*
|
1993-06-25 |
2000-11-14 |
Merrell Pharmaceuticals Inc. |
Intermediates useful for the preparation of antihistaminic piperidine derivatives
|
WO1995010278A1
(en)
*
|
1993-10-15 |
1995-04-20 |
Hoechst Marion Roussel, Inc. |
Treatment of allergic disorders with terfenadine carboxylate
|
DE69426306T2
(de)
*
|
1993-10-25 |
2001-06-07 |
Merrell Pharmaceuticals Inc., Cincinnati |
Stabile pharmazeutische zubereitungen, die terfenadine und ibuprofen enthalten
|
DK0759904T3
(da)
*
|
1994-05-16 |
2000-10-02 |
Merrell Pharma Inc |
Fremgangsmåde og diastereomere salte anvendelige til den optiske spaltning af racemisk 4-[4-[4-(hydroxydiphenylmethyl)-1-pi
|
US20030045722A1
(en)
*
|
1994-05-18 |
2003-03-06 |
Henton Daniel R. |
Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
|
CA2189007C
(en)
|
1994-05-18 |
2004-03-02 |
Daniel R. Henton |
Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof
|
CN101337922A
(zh)
*
|
1994-05-18 |
2009-01-07 |
阿温蒂斯药物公司 |
抗组胺哌啶衍生物,其多晶形物和假同晶物的无水和水合物形式的制备方法
|
CA2198084C
(en)
|
1994-08-25 |
2000-03-28 |
Timothy P. Burkholder |
Novel substituted piperidines useful for the treatment of allergic diseases
|
ES2181868T3
(es)
*
|
1995-02-28 |
2003-03-01 |
Aventis Pharma Inc |
Composicion farmaceutica para compuestos de piperidinoalcanol.
|
NZ306319A
(en)
*
|
1995-05-08 |
1999-08-30 |
Hoechst Marion Roussel Inc |
1-alkylphenyl substituted 4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butanol derivatives and medicaments
|
US5574045A
(en)
*
|
1995-06-06 |
1996-11-12 |
Hoechst Marion Roussel, Inc. |
Oral pharmaceutical composition of piperidinoalkanol compounds in solution form
|
US5906747A
(en)
*
|
1995-11-13 |
1999-05-25 |
Biosepra Inc. |
Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
|
US6211199B1
(en)
|
1995-11-17 |
2001-04-03 |
Aventis Pharmaceuticals Inc. |
Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
|
US6194406B1
(en)
|
1995-12-20 |
2001-02-27 |
Aventis Pharmaceuticals Inc. |
Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
|
US6423704B2
(en)
|
1995-12-20 |
2002-07-23 |
Aventis Pharmaceuticals Inc. |
Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
|
US6153754A
(en)
*
|
1995-12-21 |
2000-11-28 |
Albany Molecular Research, Inc. |
Process for production of piperidine derivatives
|
US6201124B1
(en)
*
|
1995-12-21 |
2001-03-13 |
Albany Molecular Research, Inc. |
Process for production of piperidine derivatives
|
US5932571A
(en)
*
|
1996-02-21 |
1999-08-03 |
Hoechst Marion Roussel, Inc. |
Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
|
US5998439A
(en)
*
|
1996-02-21 |
1999-12-07 |
Hoescht Marion Roussel, Inc. |
Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
|
US5922737A
(en)
*
|
1996-02-21 |
1999-07-13 |
Hoechst Marion Roussel, Inc. |
Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
|
US5925761A
(en)
*
|
1997-02-04 |
1999-07-20 |
Sepracor Inc. |
Synthesis of terfenadine and derivatives
|
DK0864653T3
(da)
*
|
1997-03-11 |
2004-07-12 |
Aventis Pharma Inc |
Fremgangsmåde til fremstilling af 4-(4-(4-(hydroxydiphenyl)-1-piperidinyl)-1-hydroxybutyl)-alfa,alfa-dimethylphenyleddikesyre og phosphorylerede derivater deraf
|
US6451815B1
(en)
|
1997-08-14 |
2002-09-17 |
Aventis Pharmaceuticals Inc. |
Method of enhancing bioavailability of fexofenadine and its derivatives
|
ID22891A
(id)
*
|
1997-08-26 |
1999-12-16 |
Hoechst Marion Roussel Inc |
Komposisi farmasi untuk kombinasi piperidinoalkanol-dekongestan
|
ES2200260T3
(es)
*
|
1997-12-17 |
2004-03-01 |
Aventis Pharma Deutschland Gmbh |
Procedimiento para la alquilacion de derivados de alquil-o bencilciano en presencia de trialquilaminas o trialquifosfinas.
|
KR100737710B1
(ko)
*
|
1997-12-23 |
2007-07-11 |
쉐링 코포레이션 |
하나 이상의 류코트리엔 길항제와 데스카보에톡실로라티딘를 포함하는 호흡기 질환 및 피부 질환 치료용 조성물
|
US6194431B1
(en)
|
1998-04-14 |
2001-02-27 |
Paul D. Rubin |
Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
|
AU2007200674C1
(en)
*
|
1998-07-02 |
2011-02-24 |
Aventisub Llc |
Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
|
US6683094B2
(en)
|
1998-07-02 |
2004-01-27 |
Aventis Pharmaceuticals Inc. |
Antihistaminic piperidine derivatives and intermediates for the preparation thereof
|
EP1091938B1
(en)
*
|
1998-07-02 |
2010-10-20 |
Aventisub II Inc. |
Antihistaminic piperidine derivatives and intermediates for the preparation thereof
|
US6673933B2
(en)
|
1998-07-02 |
2004-01-06 |
Aventis Pharmaceutical Inc. |
Antihistaminic piperidine derivatives and intermediates for the preparation thereof
|
GB9822170D0
(en)
*
|
1998-10-13 |
1998-12-02 |
Danbioyst Uk Ltd |
Novel formulations of fexofenadine
|
IN191492B
(da)
*
|
1999-05-25 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
US6613906B1
(en)
*
|
2000-06-06 |
2003-09-02 |
Geneva Pharmaceuticals, Inc. |
Crystal modification
|
US6613907B2
(en)
|
2000-11-08 |
2003-09-02 |
Amr Technology, Inc. |
Process for the production of piperidine derivatives with microorganisms
|
CH695216A5
(de)
*
|
2001-02-23 |
2006-01-31 |
Cilag Ag |
Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
|
AU2002305162A1
(en)
*
|
2001-04-09 |
2002-10-21 |
Teva Pharmaceutical Industries Ltd. |
Polymorphs of fexofenadine hydrochloride
|
US20030021849A1
(en)
*
|
2001-04-09 |
2003-01-30 |
Ben-Zion Dolitzky |
Polymorphs of fexofenadine hydrochloride
|
US7700779B2
(en)
*
|
2001-06-18 |
2010-04-20 |
Dr. Reddy's Laboratories Limited |
Crystalline forms of fexofenadine and its hydrochloride
|
EE200400010A
(et)
|
2001-06-18 |
2004-02-16 |
Dr. Reddy's Laboratories Ltd. |
4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormid
|
CA2465913A1
(en)
*
|
2001-11-08 |
2003-05-15 |
Judith Aronhime |
Polymorphs of fexofenadine base
|
US20030158227A1
(en)
*
|
2001-11-08 |
2003-08-21 |
Barnaba Krochmal |
Polymorphs of fexofenadine base
|
US6723348B2
(en)
*
|
2001-11-16 |
2004-04-20 |
Ethypharm |
Orodispersible tablets containing fexofenadine
|
AU2003217676B2
(en)
|
2002-02-22 |
2009-06-11 |
Takeda Pharmaceutical Company Limited |
Active agent delivery systems and methods for protecting and administering active agents
|
JP2005532356A
(ja)
*
|
2002-06-10 |
2005-10-27 |
テバ ファーマシューティカル インダストリーズ リミティド |
塩酸フェキソフェナジンの多型体xvi
|
BR0317364A
(pt)
*
|
2002-12-16 |
2005-11-16 |
Ranbaxy Lab Ltd |
Processo para a preparação de fexofenadina
|
CN1756743A
(zh)
*
|
2003-01-31 |
2006-04-05 |
兰贝克赛实验室有限公司 |
制备弗克芬得的方法
|
US20050026890A1
(en)
*
|
2003-07-31 |
2005-02-03 |
Robinson Cynthia B. |
Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
|
US20050065183A1
(en)
*
|
2003-07-31 |
2005-03-24 |
Indranil Nandi |
Fexofenadine composition and process for preparing
|
GB0319935D0
(en)
*
|
2003-08-26 |
2003-09-24 |
Cipla Ltd |
Polymorphs
|
TW200517114A
(en)
|
2003-10-15 |
2005-06-01 |
Combinatorx Inc |
Methods and reagents for the treatment of immunoinflammatory disorders
|
WO2005102999A2
(en)
*
|
2004-04-26 |
2005-11-03 |
Teva Pharmaceutical Industries Ltd. |
Crystalline forms of fexofenadine hydrochloride and processes for their preparation
|
WO2006008567A1
(en)
*
|
2004-06-18 |
2006-01-26 |
Wockhardt Limited |
Pharmaceutical compositions for piperidinoalkanol compounds
|
ITMI20041568A1
(it)
*
|
2004-07-30 |
2004-10-30 |
Dipharma Spa |
"polimorfi di fexofenadina base"
|
US7498345B2
(en)
*
|
2004-09-17 |
2009-03-03 |
Albany Molecular Research, Inc. |
Process for production of piperidine derivatives
|
US7498443B2
(en)
*
|
2004-09-17 |
2009-03-03 |
Albany Molecular Research, Inc. |
Process for production of carebastine
|
US20060148851A1
(en)
*
|
2004-09-28 |
2006-07-06 |
Shlomit Wizel |
Fexofenadine crystal form and processes for its preparation thereof
|
US20070020330A1
(en)
*
|
2004-11-24 |
2007-01-25 |
Medpointe Healthcare Inc. |
Compositions comprising azelastine and methods of use thereof
|
TR201820559T4
(tr)
*
|
2004-11-24 |
2019-01-21 |
Meda Pharmaceuticals Inc |
Azelastin içeren kompozisyonlar ve bunların kullanım metotları.
|
US8758816B2
(en)
*
|
2004-11-24 |
2014-06-24 |
Meda Pharmaceuticals Inc. |
Compositions comprising azelastine and methods of use thereof
|
JP2008120684A
(ja)
*
|
2005-03-07 |
2008-05-29 |
Kumamoto Univ |
抗アレルギー薬
|
US20080274196A1
(en)
*
|
2005-08-05 |
2008-11-06 |
Lipin Limited |
Oral Pharmaceutical Suspension Compositions Of Fexofenadine
|
US20070088065A1
(en)
*
|
2005-10-14 |
2007-04-19 |
Jie Du |
Metaxalone products, method of manufacture, and method of use
|
US20080292584A1
(en)
*
|
2005-10-14 |
2008-11-27 |
Mutual Pharmaceutical Company, Inc. |
Metaxalone products, method of manufacture, and method of use
|
WO2007049303A2
(en)
*
|
2005-10-28 |
2007-05-03 |
Ind-Swift Laboratories Limited |
An improved process for the preparation of highly pure fexofenadine
|
ZA200804550B
(en)
|
2005-11-09 |
2009-08-26 |
Combinatorx Inc |
Methods, compositions, and kits for the treatment of medical conditions
|
DOP2006000274A
(es)
*
|
2005-12-14 |
2007-10-15 |
Sanofi Aventis Us Llc |
Formulación de suspensión de fexofenadina
|
CN100443470C
(zh)
*
|
2006-07-21 |
2008-12-17 |
杭州保灵有限公司 |
一种依巴斯汀的制备方法
|
ITMI20061491A1
(it)
*
|
2006-07-27 |
2008-01-28 |
Archimica Srl |
Processo per la preparazione di fexofenadina.
|
ITMI20061492A1
(it)
*
|
2006-07-27 |
2008-01-28 |
Archimica Srl |
Processo per la preparazione di fexofenadina.
|
US20080161324A1
(en)
*
|
2006-09-14 |
2008-07-03 |
Johansen Lisa M |
Compositions and methods for treatment of viral diseases
|
EP2420236B1
(en)
|
2007-04-13 |
2015-01-14 |
Southern Research Institute |
Terfenadine as anti-angiogenic agent
|
ITMI20070987A1
(it)
*
|
2007-05-16 |
2008-11-17 |
Dipharma Francis Srl |
Procedimento per la preparazione di composti chetonici
|
US20090076080A1
(en)
*
|
2007-09-19 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched fexofenadine
|
US20090306135A1
(en)
|
2008-03-24 |
2009-12-10 |
Mukesh Kumar Sharma |
Stable amorphous fexofenadine hydrochloride
|
AU2009251743A1
(en)
*
|
2008-05-30 |
2009-12-03 |
Fairfield Clinical Trials, Llc |
Method and composition for skin inflammation and discoloration
|
US20100092479A1
(en)
*
|
2008-08-18 |
2010-04-15 |
Combinatorx (Singapore) Pte. Ltd. |
Compositions and methods for treatment of viral diseases
|
CN101585805B
(zh)
*
|
2009-06-06 |
2011-07-06 |
浙江大学宁波理工学院 |
一种抗过敏药物非索非那定盐酸盐的制备方法
|
EP2289867A3
(en)
|
2009-08-19 |
2012-04-25 |
Jubilant Organosys Limited |
A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof
|
CN101671292B
(zh)
*
|
2009-10-10 |
2011-09-07 |
浙江大学宁波理工学院 |
盐酸非索非那定的合成方法
|
US20110130711A1
(en)
*
|
2009-11-19 |
2011-06-02 |
Follica, Inc. |
Hair growth treatment
|
EP2371817A1
(en)
*
|
2010-04-01 |
2011-10-05 |
Arevipharma GmbH |
Process for the preparation of 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone and acid addition salts thereof
|
WO2011158262A1
(en)
|
2010-06-15 |
2011-12-22 |
Chemelectiva S.R.L. |
Polymorphic form of fexofenadine hydrochloride, intermediates and process for its preparation
|
CN103702961A
(zh)
|
2011-05-23 |
2014-04-02 |
赛诺菲 |
含有n-烷基的氘代化合物的制备方法
|
JP5362151B2
(ja)
|
2011-09-29 |
2013-12-11 |
塩野義製薬株式会社 |
Pgd2拮抗剤及びヒスタミン拮抗剤からなるアレルギー性鼻炎治療用医薬
|
EP2578570A1
(en)
|
2011-10-07 |
2013-04-10 |
Almirall, S.A. |
Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
|
EP2641900A1
(en)
|
2012-03-20 |
2013-09-25 |
Almirall, S.A. |
Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
|
CN102659667B
(zh)
*
|
2012-04-20 |
2013-08-14 |
浙江启明药业有限公司 |
一种非索非那定关键中间体的合成方法
|
CN103333100B
(zh)
*
|
2013-06-06 |
2016-04-06 |
池州东升药业有限公司 |
一种盐酸非索非那定的合成工艺
|
ITMI20131652A1
(it)
|
2013-10-07 |
2015-04-08 |
Dipharma Francis Srl |
Procedimento per la purificazione di derivati dell'acido 2-fenil-2-metil-propanoico
|
CN104557671B
(zh)
*
|
2013-10-10 |
2018-04-13 |
池州东升药业有限公司 |
一种非索非那定及中间体的合成方法
|
EP2949321A1
(en)
|
2014-05-26 |
2015-12-02 |
Sanovel Ilac Sanayi ve Ticaret A.S. |
Multilayer formulations of fexofenadine and montelukast
|
ES2738630T3
(es)
|
2015-01-22 |
2020-01-24 |
Sanofi Aventis Deutschland |
Procedimiento para la producción de 2-[4-(ciclopropanocarbonil)fenil]-2-metil-propanonitrilo
|
EP3365327B1
(en)
|
2015-10-22 |
2019-11-20 |
Sanofi-Aventis Deutschland GmbH |
Process for the preparation of fexofenadine and of intermediates used therein
|
GB202212656D0
(en)
|
2022-08-31 |
2022-10-12 |
Novumgen Ltd |
An orodispersible tablet of fecofenadine and it process of preparation
|
WO2024153354A1
(en)
|
2023-01-20 |
2024-07-25 |
Opella Healthcare Group Sas |
Paraben-free fexofenadine formulations
|