DK152652C - ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters - Google Patents

ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters

Info

Publication number
DK152652C
DK152652C DK307677A DK307677A DK152652C DK 152652 C DK152652 C DK 152652C DK 307677 A DK307677 A DK 307677A DK 307677 A DK307677 A DK 307677A DK 152652 C DK152652 C DK 152652C
Authority
DK
Denmark
Prior art keywords
furoyl
pyrrolooe1
aaapyrrol
theonyl
thenoyl
Prior art date
Application number
DK307677A
Other languages
Danish (da)
Other versions
DK152652B (en
DK307677A (en
Inventor
Joseph M Muchowski
Arthur F Kluge
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,283 external-priority patent/US4087539A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK307677A publication Critical patent/DK307677A/en
Priority to DK479680A priority Critical patent/DK152655C/en
Priority to DK479480A priority patent/DK479480A/en
Priority to DK479380A priority patent/DK152653C/en
Priority to DK479580A priority patent/DK152654C/en
Publication of DK152652B publication Critical patent/DK152652B/en
Application granted granted Critical
Publication of DK152652C publication Critical patent/DK152652C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK307677A 1976-07-14 1977-07-07 ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters DK152652C (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DK479680A DK152655C (en) 1976-07-14 1980-11-11 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - OR 5- (3-THENOYL) -1, 2-dihydro-3H-PYRROLOOE1,2-AAAPYRROL-1-carboxylic acid derivatives
DK479480A DK479480A (en) 1976-07-14 1980-11-11 (DL) 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) -OG 5- (3-THENOYL) -1,2-DIHYDRO-3H-PYRROL- (1) , 2-A) -PYRROL-1-CARBOXYLIC ACID ESTERS AND SALTS
DK479380A DK152653C (en) 1976-07-14 1980-11-11 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - OR 5- (3-THENOYL) -1, 2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYLIC ACID ESTERS OR SALTS
DK479580A DK152654C (en) 1976-07-14 1980-11-11 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (FUROYL) - OR 5- (3-THENOYL) -1,2- dihydro-3H-pyrrol-OE1,2-AAA-pyrrole-1-carboxylic acid

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70485776A 1976-07-14 1976-07-14
US70485776 1976-07-14
US77128377 1977-02-23
US05/771,283 US4087539A (en) 1976-07-14 1977-02-23 5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof

Publications (3)

Publication Number Publication Date
DK307677A DK307677A (en) 1978-01-15
DK152652B DK152652B (en) 1988-04-05
DK152652C true DK152652C (en) 1988-09-12

Family

ID=27107392

Family Applications (1)

Application Number Title Priority Date Filing Date
DK307677A DK152652C (en) 1976-07-14 1977-07-07 ANALOGY PROCEDURE FOR PREPARING 5- (2-FUROYL) -, 5- (2-THENOYL) -, 5- (3-FUROYL) - AND 5- (3-THEONYL) -1,2-DIHYDRO-3H-PYRROLOOE1,2 -AAAPYRROL-1-carboxylic acid esters

Country Status (26)

Country Link
JP (1) JPS539789A (en)
AR (1) AR218631A1 (en)
AU (1) AU513385B2 (en)
CA (1) CA1100140A (en)
CH (2) CH651045A5 (en)
CS (1) CS208724B2 (en)
DE (1) DE2731662A1 (en)
DK (1) DK152652C (en)
ES (2) ES460705A1 (en)
FI (1) FI63407C (en)
FR (1) FR2361396A1 (en)
GB (1) GB1554076A (en)
GR (1) GR61607B (en)
HK (1) HK17581A (en)
IE (1) IE45302B1 (en)
IL (1) IL52492A (en)
IT (1) IT1117314B (en)
MY (1) MY8100371A (en)
NL (1) NL7707652A (en)
NO (1) NO147563C (en)
NZ (1) NZ184611A (en)
PL (1) PL111408B1 (en)
PT (1) PT66779B (en)
SE (1) SE434644B (en)
SU (2) SU664566A3 (en)
YU (2) YU43157B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4140698A (en) * 1977-07-25 1979-02-20 Syntex (Usa) Inc. 1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) * 1982-06-10 1984-01-20 メルク　エンド　カムパニー　インコーポレーテツド Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) * 1982-06-10 1985-04-16 Merck & Co., Inc. 5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
HU198927B (en) * 1987-01-14 1989-12-28 Richter Gedeon Vegyeszet Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds

Also Published As

Publication number Publication date
YU43156B (en) 1989-04-30
PT66779A (en) 1977-08-01
YU47583A (en) 1984-06-30
FI63407C (en) 1983-06-10
DK152652B (en) 1988-04-05
AU513385B2 (en) 1980-11-27
HK17581A (en) 1981-05-08
SE434644B (en) 1984-08-06
AU2697677A (en) 1979-01-18
MY8100371A (en) 1981-12-31
CH651045A5 (en) 1985-08-30
FR2361396B1 (en) 1981-11-27
FI63407B (en) 1983-02-28
IT1117314B (en) 1986-02-17
NL7707652A (en) 1978-01-17
CA1100140A (en) 1981-04-28
ES470213A1 (en) 1979-09-16
NO772493L (en) 1978-01-17
CH644861A5 (en) 1984-08-31
CS208724B2 (en) 1981-09-15
GB1554076A (en) 1979-10-17
SU793400A3 (en) 1980-12-30
NZ184611A (en) 1979-03-28
IL52492A0 (en) 1977-10-31
JPS6254110B2 (en) 1987-11-13
IE45302L (en) 1978-01-14
ES460705A1 (en) 1979-10-01
PT66779B (en) 1978-12-18
DK307677A (en) 1978-01-15
PL199602A1 (en) 1979-01-29
SU664566A3 (en) 1979-05-25
NO147563B (en) 1983-01-24
IE45302B1 (en) 1982-07-28
DE2731662A1 (en) 1978-01-19
DE2731662C2 (en) 1989-11-09
JPS539789A (en) 1978-01-28
IL52492A (en) 1981-06-29
AR218631A1 (en) 1980-06-30
PL111408B1 (en) 1980-08-30
SE7708142L (en) 1978-01-15
FR2361396A1 (en) 1978-03-10
NO147563C (en) 1983-05-18
YU43157B (en) 1989-04-30
GR61607B (en) 1978-12-02
FI772154A (en) 1978-01-15
YU47683A (en) 1984-04-30

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