DK143703C - Analogifremgangsmaade til fremstilling af 1,2,3,3a,4,5-hexahydro-6-oxo-6h-indolo(3,2,1-de)=(1,5)naphthyridin-derivater eller syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 1,2,3,3a,4,5-hexahydro-6-oxo-6h-indolo(3,2,1-de)=(1,5)naphthyridin-derivater eller syreadditionssalte deraf

Info

Publication number
DK143703C
DK143703C DK161377A DK161377A DK143703C DK 143703 C DK143703 C DK 143703C DK 161377 A DK161377 A DK 161377A DK 161377 A DK161377 A DK 161377A DK 143703 C DK143703 C DK 143703C
Authority
DK
Denmark
Prior art keywords
indolo
hexahydro
oxo
preparing
acid addition
Prior art date
Application number
DK161377A
Other languages
Danish (da)
English (en)
Other versions
DK143703B (da
DK161377A (da
Inventor
G I Koletar
H Najer
J-Pg Lefevre
R Dupont
D P R L Giudicelli
C C H Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7610773A external-priority patent/FR2358146A1/fr
Priority claimed from FR7616445A external-priority patent/FR2353550A2/fr
Priority claimed from FR7632319A external-priority patent/FR2368955A2/fr
Priority claimed from FR7639035A external-priority patent/FR2374905A2/fr
Priority claimed from FR7707248A external-priority patent/FR2383181A2/fr
Priority claimed from FR7707249A external-priority patent/FR2383182A2/fr
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK161377A publication Critical patent/DK161377A/da
Publication of DK143703B publication Critical patent/DK143703B/da
Application granted granted Critical
Publication of DK143703C publication Critical patent/DK143703C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK161377A 1976-04-13 1977-04-12 Analogifremgangsmaade til fremstilling af 1,2,3,3a,4,5-hexahydro-6-oxo-6h-indolo(3,2,1-de)=(1,5)naphthyridin-derivater eller syreadditionssalte deraf DK143703C (da)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
FR7610773 1976-04-13
FR7610773A FR2358146A1 (fr) 1976-04-13 1976-04-13 Derives de la tetrahydro-1,2,3,3a indolo(3,2,1-de) (1,5)naphtyridine
FR7616445 1976-06-01
FR7616445A FR2353550A2 (fr) 1976-06-01 1976-06-01 Procede de preparation de derives de naphtyridine
FR7632319A FR2368955A2 (fr) 1976-10-27 1976-10-27 Derives de la tetrahydro-1,2,3,3a indolo (3,2,1-de) (1,5) naphtyridine
FR7632319 1976-10-27
FR7639035A FR2374905A2 (fr) 1976-12-24 1976-12-24 Derives de naphtyridine
FR7639035 1976-12-24
FR7707248A FR2383181A2 (fr) 1977-03-11 1977-03-11 Derives de naphtyridine
FR7707249A FR2383182A2 (fr) 1977-03-11 1977-03-11 Nouveaux derives de naphtyridine
FR7707249 1977-03-11
FR7707248 1977-03-11

Publications (3)

Publication Number Publication Date
DK161377A DK161377A (da) 1977-10-14
DK143703B DK143703B (da) 1981-09-28
DK143703C true DK143703C (da) 1982-04-13

Family

ID=27546337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK161377A DK143703C (da) 1976-04-13 1977-04-12 Analogifremgangsmaade til fremstilling af 1,2,3,3a,4,5-hexahydro-6-oxo-6h-indolo(3,2,1-de)=(1,5)naphthyridin-derivater eller syreadditionssalte deraf

Country Status (24)

Country Link
US (1) US4190657A (sv)
JP (1) JPS5823877B2 (sv)
AR (1) AR214519A1 (sv)
AU (1) AU506031B2 (sv)
CA (1) CA1072960A (sv)
CH (1) CH622795A5 (sv)
DD (1) DD129791A5 (sv)
DE (1) DE2716190A1 (sv)
DK (1) DK143703C (sv)
FI (1) FI63404C (sv)
GB (1) GB1543283A (sv)
GR (1) GR63658B (sv)
IE (1) IE44989B1 (sv)
IL (1) IL51853A (sv)
LU (1) LU77100A1 (sv)
MT (1) MTP811B (sv)
MX (1) MX5340E (sv)
NO (1) NO146777C (sv)
NZ (1) NZ183846A (sv)
PL (1) PL197373A1 (sv)
PT (1) PT66428B (sv)
SE (2) SE432932B (sv)
SU (1) SU655314A3 (sv)
YU (1) YU94877A (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5337696A (en) * 1976-08-26 1978-04-06 Omnium Chimique Sa Hexahydrocantinonee6 derivative
US4228168A (en) * 1978-11-22 1980-10-14 Tanabe Seiyaku Co., Ltd. Azepino [1,2,3-lm]-β-carboline compounds and pharmaceutical composition thereof
US4367230A (en) * 1980-01-04 1983-01-04 Tanabe Seiyaku Co., Ltd. Novel triazafluoranthene compound and processes for preparing the same
FR2494693A1 (fr) * 1980-11-21 1982-05-28 Synthelabo Derives de l'hexahydro-2,3,3a,4,5,6 1h-indolo(3,2,1-de)(naphtyridine-1,5), leur preparation et leur application en therapeutique
FR2517679A1 (fr) * 1981-12-03 1983-06-10 Synthelabo Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique
LU84664A1 (fr) * 1983-02-25 1984-11-08 Onmichem S A Alkyl-4-indolonaphtyridines et leur application therapeutique
EP0347980A1 (en) * 1988-06-20 1989-12-27 Duphar International Research B.V 8,9-Annelated beta-carbolines and 8,9-anelated-3,4-dihydro-beta-carbolines
CN103193776A (zh) * 2013-04-16 2013-07-10 苏州维泰生物技术有限公司 一种具有抗肿瘤疗效的新型萘啶衍生物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299078A (en) * 1962-10-01 1967-01-17 Smith Kline French Lab Pyrido [3', 4': 4, 5] pyrrolo [3, 2, 1-hi] indoles and-[3, 2, 1-ij] quinolines
US3555018A (en) * 1968-12-03 1971-01-12 Ayerst Mckenna & Harrison Thiazinopyridoindolone derivatives

Also Published As

Publication number Publication date
CH622795A5 (sv) 1981-04-30
US4190657A (en) 1980-02-26
YU94877A (en) 1983-01-21
IE44989L (en) 1977-10-13
DK143703B (da) 1981-09-28
LU77100A1 (sv) 1979-01-18
JPS52125198A (en) 1977-10-20
PT66428B (fr) 1978-09-20
DD129791A5 (de) 1978-02-08
DE2716190A1 (de) 1977-10-27
SE7704172L (sv) 1977-10-14
MX5340E (es) 1983-06-27
JPS5823877B2 (ja) 1983-05-18
PT66428A (fr) 1977-05-01
FI63404B (fi) 1983-02-28
PL197373A1 (pl) 1978-02-13
FI63404C (fi) 1983-06-10
AR214519A1 (es) 1979-06-29
IL51853A0 (en) 1977-06-30
MTP811B (en) 1978-02-20
FI771159A (sv) 1977-10-14
NO146777C (no) 1982-12-08
DK161377A (da) 1977-10-14
AU506031B2 (en) 1979-12-13
SE432932B (sv) 1984-04-30
CA1072960A (en) 1980-03-04
IE44989B1 (en) 1982-06-02
SU655314A3 (ru) 1979-03-30
GB1543283A (en) 1979-04-04
NZ183846A (en) 1980-09-12
SE8201181L (sv) 1982-05-25
NO146777B (no) 1982-08-30
GR63658B (en) 1979-11-28
AU2418977A (en) 1978-10-19
NO771263L (no) 1977-10-14
IL51853A (en) 1979-11-30

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