DK1381681T3 - NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser - Google Patents
NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelserInfo
- Publication number
- DK1381681T3 DK1381681T3 DK02720271T DK02720271T DK1381681T3 DK 1381681 T3 DK1381681 T3 DK 1381681T3 DK 02720271 T DK02720271 T DK 02720271T DK 02720271 T DK02720271 T DK 02720271T DK 1381681 T3 DK1381681 T3 DK 1381681T3
- Authority
- DK
- Denmark
- Prior art keywords
- variants
- hgf
- fragment
- applications
- growth factor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0110430.6A GB0110430D0 (en) | 2001-04-27 | 2001-04-27 | Protein variants and uses thereof |
PCT/GB2002/001941 WO2002088354A1 (en) | 2001-04-27 | 2002-04-29 | The nk1 fragment of hepatocyte growth factor/scatter factor (hgf/sf) and variants thereof, and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1381681T3 true DK1381681T3 (da) | 2007-10-29 |
Family
ID=9913640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02720271T DK1381681T3 (da) | 2001-04-27 | 2002-04-29 | NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser |
Country Status (11)
Country | Link |
---|---|
US (3) | US7179786B2 (da) |
EP (1) | EP1381681B1 (da) |
JP (2) | JP4637452B2 (da) |
AT (1) | ATE368741T1 (da) |
AU (1) | AU2002251337B2 (da) |
CA (1) | CA2440775C (da) |
DE (1) | DE60221510T2 (da) |
DK (1) | DK1381681T3 (da) |
ES (1) | ES2291460T3 (da) |
GB (1) | GB0110430D0 (da) |
WO (1) | WO2002088354A1 (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0110430D0 (en) * | 2001-04-27 | 2001-06-20 | Medical Res Council | Protein variants and uses thereof |
US20050107296A1 (en) * | 2001-10-31 | 2005-05-19 | Institut Des Vaisseaux Et Du Sang | Isolated peptide of the hepatocyte growth factor and its variants, preparation method and therapeutic use as anti-angiogenic agents |
AT412785B (de) * | 2003-12-04 | 2005-07-25 | Kungl Andreas J Dr | Gag-bindungsproteine |
US7563570B2 (en) | 2004-10-29 | 2009-07-21 | Pangaea Biotech | Method of determining a chemotherapeutic regimen for non small cell lung cancer based on BRCA1 expression |
US20090215686A1 (en) * | 2007-03-05 | 2009-08-27 | Huaqiang Eric Xu | Nk1-based polypeptides and related methods |
US8247374B2 (en) | 2007-11-09 | 2012-08-21 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium using cytokines and variants thereof |
WO2011103382A2 (en) * | 2010-02-22 | 2011-08-25 | The Brigham And Women's Hospital | Compositions and methods for inducing angiogenesis |
US9556248B2 (en) | 2010-03-19 | 2017-01-31 | The Board Of Trustees Of The Leland Stanford Junior University | Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists |
DK2638173T3 (da) | 2010-11-08 | 2019-09-30 | Univ Leland Stanford Junior | Fusionsproteiner omfattende et manipuleret knottin-peptid og anvendelser deraf |
WO2013037521A1 (en) | 2011-09-16 | 2013-03-21 | Medical Research Council | Modified hgf-1k1 polypeptide |
WO2013037520A1 (en) | 2011-09-16 | 2013-03-21 | Glaxo Group Limited | Modified hgf-1k1 polypeptide |
CA2973300C (en) | 2015-01-21 | 2024-03-19 | Universite Des Sciences Et Technologies De Lille-Lille 1 | Met receptor agonist proteins |
BR112018076306A2 (pt) | 2016-06-17 | 2019-03-26 | Magenta Therapeutics, Inc. | composições e métodos para a supressão de células cd117+ |
GB201611123D0 (en) * | 2016-06-27 | 2016-08-10 | Euremab Srl | Anti met antibodiesand uses thereof |
KR20190107097A (ko) | 2017-01-20 | 2019-09-18 | 마젠타 테라퓨틱스 인코포레이티드 | Cd137+ 세포의 고갈을 위한 조성물 및 방법 |
IT201800000535A1 (it) | 2018-01-03 | 2019-07-03 | Procedimenti per la cura del cancro. | |
CN109535243B (zh) * | 2019-01-07 | 2019-09-24 | 北京诺思兰德生物技术股份有限公司 | 人肝细胞生长因子突变体及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5594115A (en) * | 1990-04-09 | 1997-01-14 | Pharmacia & Upjohn Company | Process of purifying recombinant proteins and compounds useful in such process |
US6566098B1 (en) * | 1990-09-14 | 2003-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | DNA encoding truncated hepatocyte growth factor variants |
ATE222603T1 (de) * | 1992-05-18 | 2002-09-15 | Genentech Inc | Hepatozytwachstumfaktor variante |
JP4006058B2 (ja) * | 1997-03-11 | 2007-11-14 | 第一三共株式会社 | 多臓器不全予防及び/又は治療剤 |
GB0110430D0 (en) * | 2001-04-27 | 2001-06-20 | Medical Res Council | Protein variants and uses thereof |
-
2001
- 2001-04-27 GB GBGB0110430.6A patent/GB0110430D0/en not_active Ceased
-
2002
- 2002-04-29 WO PCT/GB2002/001941 patent/WO2002088354A1/en active IP Right Grant
- 2002-04-29 ES ES02720271T patent/ES2291460T3/es not_active Expired - Lifetime
- 2002-04-29 CA CA2440775A patent/CA2440775C/en not_active Expired - Fee Related
- 2002-04-29 EP EP02720271A patent/EP1381681B1/en not_active Expired - Lifetime
- 2002-04-29 AU AU2002251337A patent/AU2002251337B2/en not_active Ceased
- 2002-04-29 US US10/475,616 patent/US7179786B2/en not_active Expired - Fee Related
- 2002-04-29 DE DE60221510T patent/DE60221510T2/de not_active Expired - Lifetime
- 2002-04-29 DK DK02720271T patent/DK1381681T3/da active
- 2002-04-29 JP JP2002585635A patent/JP4637452B2/ja not_active Expired - Fee Related
- 2002-04-29 AT AT02720271T patent/ATE368741T1/de not_active IP Right Cessation
-
2007
- 2007-01-26 US US11/627,761 patent/US7795214B2/en not_active Expired - Fee Related
-
2010
- 2010-08-17 US US12/858,189 patent/US8232258B2/en not_active Expired - Fee Related
- 2010-09-17 JP JP2010208693A patent/JP2011045370A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US7795214B2 (en) | 2010-09-14 |
JP4637452B2 (ja) | 2011-02-23 |
US7179786B2 (en) | 2007-02-20 |
AU2002251337B2 (en) | 2007-08-02 |
DE60221510T2 (de) | 2008-04-17 |
US8232258B2 (en) | 2012-07-31 |
US20080167224A1 (en) | 2008-07-10 |
GB0110430D0 (en) | 2001-06-20 |
JP2011045370A (ja) | 2011-03-10 |
US20040236073A1 (en) | 2004-11-25 |
EP1381681B1 (en) | 2007-08-01 |
DE60221510D1 (de) | 2007-09-13 |
ES2291460T3 (es) | 2008-03-01 |
US20110021612A1 (en) | 2011-01-27 |
WO2002088354A1 (en) | 2002-11-07 |
CA2440775C (en) | 2013-02-26 |
EP1381681A1 (en) | 2004-01-21 |
CA2440775A1 (en) | 2002-11-07 |
JP2004532032A (ja) | 2004-10-21 |
ATE368741T1 (de) | 2007-08-15 |
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