DK137007C - Analogifremgangsmaade til fremstilling af isoquinolinderivater - Google Patents

Analogifremgangsmaade til fremstilling af isoquinolinderivater

Info

Publication number
DK137007C
DK137007C DK639674A DK639674A DK137007C DK 137007 C DK137007 C DK 137007C DK 639674 A DK639674 A DK 639674A DK 639674 A DK639674 A DK 639674A DK 137007 C DK137007 C DK 137007C
Authority
DK
Denmark
Prior art keywords
preparation
isoquinoline derivatives
analogical procedure
analogical
procedure
Prior art date
Application number
DK639674A
Other languages
English (en)
Other versions
DK137007B (da
DK639674A (da
Inventor
W Mehrhof
R Pohlke
K H Becker
H-J Schliep
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DK639674A publication Critical patent/DK639674A/da
Publication of DK137007B publication Critical patent/DK137007B/da
Application granted granted Critical
Publication of DK137007C publication Critical patent/DK137007C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK639674A 1973-12-10 1974-12-09 Analogifremgangsmaade til fremstilling af isoquinolinderivater DK137007C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2361390A DE2361390A1 (de) 1973-12-10 1973-12-10 Isochinolinderivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK639674A DK639674A (da) 1975-08-11
DK137007B DK137007B (da) 1978-01-02
DK137007C true DK137007C (da) 1978-06-05

Family

ID=5900348

Family Applications (1)

Application Number Title Priority Date Filing Date
DK639674A DK137007C (da) 1973-12-10 1974-12-09 Analogifremgangsmaade til fremstilling af isoquinolinderivater

Country Status (18)

Country Link
US (1) US3985881A (da)
JP (1) JPS5088077A (da)
AT (1) AT351026B (da)
BE (1) BE823027A (da)
CA (1) CA1053675A (da)
CH (1) CH605776A5 (da)
CS (1) CS188933B2 (da)
DD (1) DD115666A5 (da)
DE (1) DE2361390A1 (da)
DK (1) DK137007C (da)
ES (1) ES432716A1 (da)
FR (1) FR2253522B1 (da)
GB (1) GB1447611A (da)
HU (1) HU171483B (da)
IL (1) IL46160A0 (da)
NL (1) NL7416050A (da)
SE (1) SE7415247L (da)
ZA (1) ZA747820B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4556712A (en) * 1981-05-20 1985-12-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
DE3713743A1 (de) * 1987-04-24 1988-11-17 Boehringer Ingelheim Kg Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0330360B1 (en) * 1988-02-19 1993-12-01 SmithKline Beecham Farmaceutici S.p.A. 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists
PT89780A (pt) * 1988-02-23 1989-10-04 Glaxo Group Ltd Processo para a preparacao de derivados da tetrahidroisoquinolina
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
GB0225884D0 (en) * 2002-11-06 2002-12-11 Glaxo Group Ltd Novel compounds
PE20151501A1 (es) * 2012-12-21 2015-11-08 Epizyme Inc Inhibidores de prmt5 y sus usos
AU2016316436B2 (en) * 2015-09-01 2021-04-29 Merck Patent Gmbh Method for the production of praziquantel and precursors thereof
US20180305334A1 (en) * 2015-10-14 2018-10-25 Aquinnah Pharmaceuticals, Inc. Compounds, compositions and methods of use against stress granules
MX2020003242A (es) 2017-09-22 2020-09-18 Jubilant Epipad LLC Compuestos heterociclicos como inhibidores de pad.
IL272667B (en) 2017-10-18 2022-09-01 Jubilant Epipad LLC Imidazo-pyridine compounds as pad inhibitors
US11629135B2 (en) 2017-11-06 2023-04-18 Jubilant Prodell Llc Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation
WO2019102494A1 (en) 2017-11-24 2019-05-31 Jubilant Biosys Limited Heterocyclic compounds as prmt5 inhibitors
CN112105610B (zh) 2018-03-13 2024-01-26 朱比连特普罗德尔有限责任公司 作为pd1/pd-l1相互作用/活化的抑制剂的双环化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2612503A (en) * 1949-04-19 1952-09-30 Smith Kline French Lab Basic ether-substituted isoquinolines
US2640829A (en) * 1950-11-10 1953-06-02 Smith Kline French Lab Isoquinolyl heterocyclic ethers
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3600394A (en) * 1968-05-17 1971-08-17 Searle & Co 2-aminoalkyl-3-arylisocarbostyrils

Also Published As

Publication number Publication date
ATA981974A (de) 1978-12-15
HU171483B (hu) 1978-01-28
DK137007B (da) 1978-01-02
JPS5088077A (da) 1975-07-15
FR2253522B1 (da) 1978-06-30
AU7625774A (en) 1976-06-10
IL46160A0 (en) 1975-02-10
BE823027A (fr) 1975-06-06
AT351026B (de) 1979-07-10
CS188933B2 (en) 1979-03-30
DK639674A (da) 1975-08-11
PL93405B1 (da) 1977-05-30
GB1447611A (en) 1976-08-25
ZA747820B (en) 1975-12-31
DD115666A5 (da) 1975-10-12
ES432716A1 (es) 1977-03-01
CA1053675A (en) 1979-05-01
CH605776A5 (da) 1978-10-13
DE2361390A1 (de) 1975-06-19
US3985881A (en) 1976-10-12
SE7415247L (da) 1975-06-11
FR2253522A1 (da) 1975-07-04
NL7416050A (nl) 1975-06-12

Similar Documents

Publication Publication Date Title
DK145676C (da) Analogifremgangsmaade til fremstilling af oxoalkyldialkylxanthiner
DK137007C (da) Analogifremgangsmaade til fremstilling af isoquinolinderivater
DK156642C (da) Analogifremgangsmaade til fremstilling af napthalenderivater
DK137124B (da) Analogifremgangsmade til fremstilling af isoquinolinderivater
DK132892C (da) Analogifremgangsmade til fremstilling af 4-aminoquinazoliner
DK147004C (da) Analogifremgangsmaade til fremstilling af oxygenerede alkylxanthinderivater
DK136155C (da) Analogifremgangsmade til fremstilling af pyrazoloner-(5)
DK139751B (da) Analogifremgangsmaade til fremstilling af n-benzhydryl-n!-p-hydroxybenzyl-piperaziner
DK136249C (da) Analogifremgangsmade til fremstilling af xanthenderivater
DK144270C (da) Analogifremgangsmaade til fremstilling af n-carbamoyl-2-phenylethensulfonamider
DK133810C (da) Analogifremgangsmade til fremstilling af adeninderivater
DK136978C (da) Analogifremgangsmaade til fremstilling af tricycliske sulfoximidderivater
AR209281A1 (es) Procedimiento de preparacion de derivados de ciclopropilfenilpirrolidina
DK137185C (da) Analogifremgangsmaade til fremstilling af tiofenderivater
DK142578A (da) Analogifremgangsmaade til fremstilling af 4-benzazininderivater
DK133303C (da) Analogifremgangsmade til fremstilling af digitoxinorthoformiater
DK133950C (da) Fremgangsmade til fremstilling af halogenholdige tertiere phosphinoxider
DK133011C (da) Analogifremgangsmade til fremstilling af 4'-dehydro-oleandrin
DK132832C (da) Analogifremgangsmade til fremstilling af alfa-acyldigitoxiner
DK132283C (da) Analogifremgangsmade til fremstilling af 15-oxasteroider
DK379276A (da) Analogifremgangsmade til fremstilling af 2-hydroxyphenyl-1-oxa-4-azaspiroalkan-derivater
DK370776A (da) Fremgangsmade til fremstilling af d-xylofuranosederivater
DK370876A (da) Fremgangsmade til fremstilling af d-xylofuranosederivater
DK370976A (da) Fremgangsmade til fremstilling af d-xylofuranosederivater
DK132439C (da) Analogifremgangsmade til fremstilling af 17-steroidylestratriener