BE823027A - Derives d'isoquinoleine et leur procede de preparation - Google Patents
Derives d'isoquinoleine et leur procede de preparationInfo
- Publication number
- BE823027A BE823027A BE151221A BE151221A BE823027A BE 823027 A BE823027 A BE 823027A BE 151221 A BE151221 A BE 151221A BE 151221 A BE151221 A BE 151221A BE 823027 A BE823027 A BE 823027A
- Authority
- BE
- Belgium
- Prior art keywords
- isoquinoleine
- derivatives
- preparation process
- preparation
- isoquinoleine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
BE823027A true BE823027A (fr) | 1975-06-06 |
Family
ID=5900348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE151221A BE823027A (fr) | 1973-12-10 | 1974-12-06 | Derives d'isoquinoleine et leur procede de preparation |
Country Status (18)
Country | Link |
---|---|
US (1) | US3985881A (fr) |
JP (1) | JPS5088077A (fr) |
AT (1) | AT351026B (fr) |
BE (1) | BE823027A (fr) |
CA (1) | CA1053675A (fr) |
CH (1) | CH605776A5 (fr) |
CS (1) | CS188933B2 (fr) |
DD (1) | DD115666A5 (fr) |
DE (1) | DE2361390A1 (fr) |
DK (1) | DK137007C (fr) |
ES (1) | ES432716A1 (fr) |
FR (1) | FR2253522B1 (fr) |
GB (1) | GB1447611A (fr) |
HU (1) | HU171483B (fr) |
IL (1) | IL46160A0 (fr) |
NL (1) | NL7416050A (fr) |
SE (1) | SE7415247L (fr) |
ZA (1) | ZA747820B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
EP0330360B1 (fr) * | 1988-02-19 | 1993-12-01 | SmithKline Beecham Farmaceutici S.p.A. | 1,2,3,4-Tetrahydroisoquinolines, procédé pour leur préparation et leur utilisation comme agoniste de Kappa-récepteur |
KR890012970A (ko) * | 1988-02-23 | 1989-09-20 | 추후보충 | 테트라히드로 이소퀴놀린 유도체 |
DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
ES2701069T3 (es) * | 2012-12-21 | 2019-02-20 | Epizyme Inc | Inhibidores de PRMT5 y sus usos |
CN108026047A (zh) * | 2015-09-01 | 2018-05-11 | 默克专利股份公司 | 吡喹酮及其前体的生产方法 |
CA3001857A1 (fr) * | 2015-10-14 | 2017-04-20 | Aquinnah Pharmaceuticals, Inc. | Composes, compositions et methodes d'utilisation contre des granules de stress |
EP3684767B1 (fr) | 2017-09-22 | 2024-04-24 | Jubilant Epipad LLC | Composés hétérocycliques en tant qu'inhibiteurs de pad |
FI3697785T3 (fi) | 2017-10-18 | 2023-04-03 | Jubilant Epipad LLC | Imidatsopyridiiniyhdisteitä pad:n estäjinä |
CN111386265A (zh) | 2017-11-06 | 2020-07-07 | 朱比连特普罗德尔有限责任公司 | 作为pd1/pd-l1活化的抑制剂的嘧啶衍生物 |
IL274762B2 (en) | 2017-11-24 | 2023-10-01 | Jubilant Episcribe Llc | Novel heterocyclic compounds as PRMT5 inhibitors |
KR20200131845A (ko) | 2018-03-13 | 2020-11-24 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 상호작용/활성화 억제제로서의 비사이클릭 화합물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-06 BE BE151221A patent/BE823027A/fr unknown
- 1974-12-06 CA CA215,386A patent/CA1053675A/fr not_active Expired
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES432716A1 (es) | 1977-03-01 |
IL46160A0 (en) | 1975-02-10 |
DD115666A5 (fr) | 1975-10-12 |
US3985881A (en) | 1976-10-12 |
ZA747820B (en) | 1975-12-31 |
PL93405B1 (fr) | 1977-05-30 |
FR2253522A1 (fr) | 1975-07-04 |
NL7416050A (nl) | 1975-06-12 |
AT351026B (de) | 1979-07-10 |
CH605776A5 (fr) | 1978-10-13 |
GB1447611A (en) | 1976-08-25 |
HU171483B (hu) | 1978-01-28 |
CS188933B2 (en) | 1979-03-30 |
DK639674A (fr) | 1975-08-11 |
DK137007B (da) | 1978-01-02 |
ATA981974A (de) | 1978-12-15 |
SE7415247L (fr) | 1975-06-11 |
DK137007C (da) | 1978-06-05 |
CA1053675A (fr) | 1979-05-01 |
AU7625774A (en) | 1976-06-10 |
DE2361390A1 (de) | 1975-06-19 |
FR2253522B1 (fr) | 1978-06-30 |
JPS5088077A (fr) | 1975-07-15 |
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