DK1364044T3 - Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin - Google Patents

Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin

Info

Publication number
DK1364044T3
DK1364044T3 DK01987011.2T DK01987011T DK1364044T3 DK 1364044 T3 DK1364044 T3 DK 1364044T3 DK 01987011 T DK01987011 T DK 01987011T DK 1364044 T3 DK1364044 T3 DK 1364044T3
Authority
DK
Denmark
Prior art keywords
tcpp
porphine
carboxyphenyl
tetrakis
tissue samples
Prior art date
Application number
DK01987011.2T
Other languages
English (en)
Inventor
Jeffrey L Garwin
Original Assignee
Biomoda Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomoda Inc filed Critical Biomoda Inc
Application granted granted Critical
Publication of DK1364044T3 publication Critical patent/DK1364044T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DK01987011.2T 2000-11-17 2001-11-19 Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin DK1364044T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24950500P 2000-11-17 2000-11-17
PCT/US2001/043238 WO2002042267A2 (en) 2000-11-17 2001-11-19 Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine

Publications (1)

Publication Number Publication Date
DK1364044T3 true DK1364044T3 (da) 2012-05-07

Family

ID=22943735

Family Applications (2)

Application Number Title Priority Date Filing Date
DK11159888.4T DK2372361T3 (da) 2000-11-17 2001-11-19 Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin
DK01987011.2T DK1364044T3 (da) 2000-11-17 2001-11-19 Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK11159888.4T DK2372361T3 (da) 2000-11-17 2001-11-19 Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin

Country Status (11)

Country Link
US (8) US6838248B2 (da)
EP (2) EP2372361B1 (da)
JP (3) JP4307070B2 (da)
CN (1) CN1545557A (da)
AT (1) ATE541214T1 (da)
AU (2) AU3926902A (da)
CA (2) CA2725716C (da)
DK (2) DK2372361T3 (da)
ES (2) ES2380261T3 (da)
MX (1) MXPA03004406A (da)
WO (1) WO2002042267A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3926902A (en) 2000-11-17 2002-06-03 Biomoda Inc Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
US7869033B2 (en) * 2003-12-24 2011-01-11 Vadivel Masilamani Cancer detection by optical analysis of body fluids
US8208142B2 (en) * 2003-12-24 2012-06-26 King Salid University Lung cancer detection by optical analysis of body fluids
US8213005B2 (en) 2003-07-22 2012-07-03 King Saud University Method for discriminating between benign and malignant prostate tumors
EP2270712A1 (en) * 2009-06-30 2011-01-05 Koninklijke Philips Electronics N.V. Quality detection method and device for cell and tissue samples
WO2011009137A1 (en) * 2009-07-17 2011-01-20 Biomoda, Inc. System and method for analyzing samples labeled with 5, 10, 15, 20 tetrakis (4-carboxyphenyl) porphine (tcpp)
WO2012065004A2 (en) * 2010-11-12 2012-05-18 Incelldx, Inc. Methods and systems for predicting whether a subject has a cervical intraepithelial neoplasia (cin) lesion from a suspension sample of cervical cells
US9779283B2 (en) 2011-01-05 2017-10-03 The Board Of Trustees Of The University Of Illinois Automated prostate tissue referencing for cancer detection and diagnosis
US9230063B2 (en) * 2011-01-05 2016-01-05 The Board Of Trustees Of The University Of Illinois Automated prostate tissue referencing for cancer detection and diagnosis
EP2834367A4 (en) * 2012-04-05 2016-03-23 Becton Dickinson Co SAMPLE PREPARATION FOR FLOW CYTOMETRY
US9933341B2 (en) 2012-04-05 2018-04-03 Becton, Dickinson And Company Sample preparation for flow cytometry
WO2014107740A2 (en) * 2013-01-07 2014-07-10 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
JP6518230B2 (ja) 2013-03-15 2019-05-22 ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ 炎症、自己免疫疾患、および疼痛を治療する方法
ES2735994T3 (es) 2013-04-11 2019-12-23 Cytocore Inc Método para estimar el riesgo de que la displasia evolucione a cáncer en un sujeto
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
JP2019523783A (ja) 2016-06-16 2019-08-29 オンコセレクト セラピューティクス，エルエルシー がんの治療に有用なポルフィリン化合物及び組成物
MX2020010825A (es) * 2018-04-13 2021-01-15 Bioaffinity Tech Inc Sistema y metodo para determinar la salud pulmonar.
JP2022552019A (ja) 2019-10-18 2022-12-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 病的血管障害の治療のための作用物質としての３－フェニルスルホニル－キノリン誘導体
WO2021076903A1 (en) * 2019-10-18 2021-04-22 The Regents Of The University Of California Compositions and methods for detecting plxdc1 and plxdc2 in human tissues
CN110927369A (zh) * 2019-12-11 2020-03-27 安徽安龙基因科技有限公司 一种利用tcpp联合cep探针鉴定循环肿瘤细胞的试剂盒及应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485086A (en) * 1983-04-11 1984-11-27 Wong Dennis W Radiolabeled tumor imaging agent and method of preparation
US4930516B1 (en) * 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US4783529A (en) * 1985-12-03 1988-11-08 Research Corporation Technologies Rapid synthesis of radiolabeled porphyrin complexes for medical application
US5162231A (en) * 1989-10-25 1992-11-10 Cole Dean A Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
US4857300A (en) * 1987-07-27 1989-08-15 Cytocorp, Inc. Cytological and histological fixative formulation and methods for using same
US5004811A (en) * 1987-12-24 1991-04-02 Nippon Petrochemicals Company, Ltd. Tetrapyrrole aminocarboxylic acids
EP0553116A1 (en) * 1990-10-05 1993-08-04 Queen's University At Kingston Porphyrin derivatives
DE59009561D1 (de) 1990-12-20 1995-09-28 Siemens Ag Beatmungsgerät mit vom Patientengasfluss abhängiger Triggerempfindlichkeit.
US5837865A (en) * 1993-10-15 1998-11-17 Trustees Of The University Of Pennsylvania Phosphorescent dendritic macromolecular compounds for imaging tissue oxygen
DE19503163A1 (de) * 1995-02-01 1996-08-08 Bayer Ag Verfahren zur Reinigung von 4-Hydroxybenzaldehyd enthaltenden Reaktionsgemischen
US6706473B1 (en) 1996-12-06 2004-03-16 Nanogen, Inc. Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
US6274086B1 (en) * 1996-12-16 2001-08-14 The Trustees Of The University Of Pennsylvania Apparatus for non-invasive imaging oxygen distribution in multi-dimensions
US6316215B1 (en) * 1999-12-27 2001-11-13 Edwin L. Adair Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods
JP3753866B2 (ja) 1998-07-01 2006-03-08 株式会社日立製作所 自己救済型光ネットワーク
US7904139B2 (en) 1999-08-26 2011-03-08 Non-Invasive Technology Inc. Optical examination of biological tissue using non-contact irradiation and detection
US6190877B1 (en) * 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
AU3926902A (en) * 2000-11-17 2002-06-03 Biomoda Inc Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
DE602004018272D1 (de) 2003-02-13 2009-01-22 Hamamatsu Photonics Kk Fluoreszenzkorrelierte spektrometrische analyseeinrichtung
US20070172392A1 (en) 2005-12-13 2007-07-26 Sen Chandan K Apparatus, system and method for tissue oximetry
US8983581B2 (en) 2008-05-27 2015-03-17 Massachusetts Institute Of Technology System and method for large field of view, single cell analysis
US9155471B2 (en) 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
WO2011009137A1 (en) 2009-07-17 2011-01-20 Biomoda, Inc. System and method for analyzing samples labeled with 5, 10, 15, 20 tetrakis (4-carboxyphenyl) porphine (tcpp)

Also Published As

Publication number Publication date
US8975038B2 (en) 2015-03-10
EP1364044A2 (en) 2003-11-26
AU2002239269B2 (en) 2008-08-21
US7384764B2 (en) 2008-06-10
US20050233410A1 (en) 2005-10-20
JP2009020122A (ja) 2009-01-29
ES2523378T3 (es) 2014-11-25
DK2372361T3 (da) 2014-11-10
US20050079561A1 (en) 2005-04-14
CA2429526A1 (en) 2002-05-30
ATE541214T1 (de) 2012-01-15
AU3926902A (en) 2002-06-03
CA2725716C (en) 2015-02-10
US20150177245A1 (en) 2015-06-25
US7670799B2 (en) 2010-03-02
EP2372361B1 (en) 2014-08-06
EP2372361A1 (en) 2011-10-05
JP4307070B2 (ja) 2009-08-05
US20020115121A1 (en) 2002-08-22
US6838248B2 (en) 2005-01-04
JP2004536275A (ja) 2004-12-02
US20090004690A1 (en) 2009-01-01
JP4768005B2 (ja) 2011-09-07
JP2011185947A (ja) 2011-09-22
EP1364044B1 (en) 2012-01-11
CA2725716A1 (en) 2002-05-30
CA2429526C (en) 2011-03-15
WO2002042267A2 (en) 2002-05-30
WO2002042267A3 (en) 2003-07-10
US7960138B2 (en) 2011-06-14
US8486656B2 (en) 2013-07-16
CN1545557A (zh) 2004-11-10
US20120149057A1 (en) 2012-06-14
US9417241B2 (en) 2016-08-16
US20100216169A1 (en) 2010-08-26
US20140162287A1 (en) 2014-06-12
EP1364044A4 (en) 2008-11-26
MXPA03004406A (es) 2004-10-15
ES2380261T3 (es) 2012-05-10

Similar Documents

Publication Publication Date Title
DK1364044T3 (da) Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin
IL157380A0 (en) Mediator stabilized reagent compositions and methods for their use in electrochemical analyte detection assays
PT2280283E (pt) Células marcadas para uso como controlo funcional interno em ensaios de deteção de células raras
WO2006014351A3 (en) Exploring fluorophore microenvironments
DK1067384T3 (da) Prøvedetektion for at igangsætte tidsmålingen i en elektrokemisk test
SE0000538L (sv) Metoder och kit för analytdetektion mha proximitets-probning
ZA200800974B (en) Apoptosis sensitivity to Apo2L/TRAIL by testing for 'GalNac-T14 expression in cells/tissues
DK1774037T3 (da) Analyser og fremgangsmåder, der anvender biomarkører
GB2343248B (en) Optical measurement of fluid samples
DE602005014835D1 (de) Methode, Apparat, Reagenzkit und Reagenz zur Unterscheidung von Erythrozyten in biologischen Proben
NO20052992D0 (no) Markorproteiner for diagnostisering av leversykdom og fremgangsmate for diagnostisering av leversykdom.
WO2005008252A3 (en) Methods and compositions for assaying homocysteine
AU2849300A (en) Methods and assay kits for detecting mononuclear cell phenotype
GB0008618D0 (en) Analyte detection & apparatus therefor
DK1513878T3 (da) Sammensætninger og fremgangsmåder til analyse af Apo B48 og Apo B100
AU2003260457A1 (en) A method and kit for the quantitative and/or qualitative detection of components in a sample
AU2002223536A1 (en) Method for the detection and measurement of biomass
DK0746773T3 (da) Detektering af elektromagnetiske felter
DE60139056D1 (de) Blutzellen-Detektor, Blutanalysegerät und Blutanalyseverfahren unter Verwendung des Detektors
DE69833218D1 (de) Verfahren und kit zum nachweis von cryptosporidium oozysten
EP2407787A3 (en) Method for detection of L523S expression in biological samples
ATE520034T1 (de) Quantitative analyse einer biologischen probe unbekannter menge
DK1314038T3 (da) Fremgangsmåde til analyse af afföringspröver til diagnostiske formål
WO2004016802A3 (en) Methods and apparatus for preparing and assaying biological samples to determine protein concentration
AU2003273746A1 (en) Method for detecting analytes