DK1219599T3 - Vitamin-D-derivater som har substituenter i 2-alfa-position - Google Patents

Vitamin-D-derivater som har substituenter i 2-alfa-position

Info

Publication number
DK1219599T3
DK1219599T3 DK00955023.7T DK00955023T DK1219599T3 DK 1219599 T3 DK1219599 T3 DK 1219599T3 DK 00955023 T DK00955023 T DK 00955023T DK 1219599 T3 DK1219599 T3 DK 1219599T3
Authority
DK
Denmark
Prior art keywords
group
vitamin
substituents
saturated aliphatic
derivatives
Prior art date
Application number
DK00955023.7T
Other languages
English (en)
Inventor
Hiroaki Takayama
Toshie Fujishima
Yoshitomo Suhara
Ken-Ichi Nihei
Katsuhiro Konno
Original Assignee
Hiroaki Takayama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hiroaki Takayama filed Critical Hiroaki Takayama
Application granted granted Critical
Publication of DK1219599T3 publication Critical patent/DK1219599T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK00955023.7T 1999-08-27 2000-08-25 Vitamin-D-derivater som har substituenter i 2-alfa-position DK1219599T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24165099 1999-08-27
PCT/JP2000/005743 WO2001016099A1 (fr) 1999-08-27 2000-08-25 DÉRIVÉS DE VITAMINE D AYANT DES SUBSTITUANTS À LA POSITION 2$g(a)

Publications (1)

Publication Number Publication Date
DK1219599T3 true DK1219599T3 (da) 2010-05-25

Family

ID=17077481

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00955023.7T DK1219599T3 (da) 1999-08-27 2000-08-25 Vitamin-D-derivater som har substituenter i 2-alfa-position

Country Status (7)

Country Link
US (1) US20050113349A1 (da)
EP (1) EP1219599B1 (da)
AT (1) ATE462689T1 (da)
AU (1) AU6730600A (da)
DE (1) DE60044090D1 (da)
DK (1) DK1219599T3 (da)
WO (1) WO2001016099A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4443933B2 (ja) * 2002-02-25 2010-03-31 中外製薬株式会社 蛍光偏光法を用いたビタミンｄ３受容体結合活性測定方法
JP2011241170A (ja) * 2010-05-18 2011-12-01 Mercian Corp ビタミンｄ誘導体およびその製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184112B1 (en) * 1984-11-27 1990-05-09 Chugai Seiyaku Kabushiki Kaisha Novel vitamin d derivatives and process for producing the same
US5378695A (en) * 1989-02-23 1995-01-03 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Vitamin D analogues
US5401732A (en) * 1989-02-23 1995-03-28 Leo Pharmaceutical Products Ltd. A/S Kemiske Fabrik Produkionsaktiese Skab Vitamin D analogues
JP3213092B2 (ja) * 1991-11-01 2001-09-25 中外製薬株式会社 ２β位に置換基を有するビタミンＤ誘導体
JP3493037B2 (ja) * 1991-12-18 2004-02-03 中外製薬株式会社 ２２−オキサコレカルシフェロール誘導体とその製造方法
JP2898882B2 (ja) * 1993-04-05 1999-06-02 ウイスコンシン アラムナイ リサーチ フオンデーシヨン ２−位に置換基を有する１９−ノル−ビタミンｄ３ 化合物
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
WO1996001811A1 (en) * 1994-07-11 1996-01-25 The Johns-Hopkins University 2-substituted 1,25-dihydroxyvitamin d3 derivatives
US5883271A (en) * 1995-01-23 1999-03-16 Chugai Seiyaku Kabushiki Kaisha 2-Substituted vitamin D derivatives
US5877168A (en) * 1995-02-10 1999-03-02 Chugai Seiyaku Kabushiki Kaisha Vitamin D derivative with substituent at the 2β-position
DK0771789T3 (da) * 1995-10-30 2000-06-13 Hoffmann La Roche 1 alpha, 26-dihydroxy-D-homo-vitamin D3
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
DE69826285T2 (de) * 1997-06-06 2005-10-20 Wisconsin Alumni Research Foundation, Madison Verwendung von vitamin d verbindungen zur vorbeugung von transplantatabstossung
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
WO2000066548A1 (fr) * 1999-04-28 2000-11-09 Chugai Seiyaku Kabushiki Kaisha Derives 2-alkyles de vitamine d
ES2309069T3 (es) * 2000-05-31 2008-12-16 Wisconsin Alumni Research Foundation Compuestos de 2-etil y 2-etiliden-19-nor-vitamina d.

Also Published As

Publication number Publication date
EP1219599B1 (en) 2010-03-31
ATE462689T1 (de) 2010-04-15
EP1219599A1 (en) 2002-07-03
AU6730600A (en) 2001-03-26
WO2001016099A1 (fr) 2001-03-08
DE60044090D1 (de) 2010-05-12
US20050113349A1 (en) 2005-05-26
EP1219599A4 (en) 2002-09-11

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