DK1218382T3 - Bicykliske imidazo-3-ylaminderivater - Google Patents

Bicykliske imidazo-3-ylaminderivater

Info

Publication number
DK1218382T3
DK1218382T3 DK00967692T DK00967692T DK1218382T3 DK 1218382 T3 DK1218382 T3 DK 1218382T3 DK 00967692 T DK00967692 T DK 00967692T DK 00967692 T DK00967692 T DK 00967692T DK 1218382 T3 DK1218382 T3 DK 1218382T3
Authority
DK
Denmark
Prior art keywords
bicyclic imidazo
ylamine derivatives
ylamine
derivatives
imidazo
Prior art date
Application number
DK00967692T
Other languages
Danish (da)
English (en)
Inventor
Matthias Gerlach
Corinna Maul
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999148438 external-priority patent/DE19948438B4/de
Priority claimed from DE19948434A external-priority patent/DE19948434A1/de
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of DK1218382T3 publication Critical patent/DK1218382T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00967692T 1999-10-08 2000-09-18 Bicykliske imidazo-3-ylaminderivater DK1218382T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1999148438 DE19948438B4 (de) 1999-10-08 1999-10-08 Bicyclische Imidazo-3-aminderivate
DE19948434A DE19948434A1 (de) 1999-10-08 1999-10-08 Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine
PCT/EP2000/009096 WO2001027111A2 (de) 1999-10-08 2000-09-18 Bicyclische imidazo-3-yl-aminderivate

Publications (1)

Publication Number Publication Date
DK1218382T3 true DK1218382T3 (da) 2004-03-22

Family

ID=26055218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00967692T DK1218382T3 (da) 1999-10-08 2000-09-18 Bicykliske imidazo-3-ylaminderivater

Country Status (26)

Country Link
US (1) US6638933B2 (es)
EP (1) EP1218382B1 (es)
JP (1) JP2003511451A (es)
KR (1) KR100756592B1 (es)
CN (1) CN1257169C (es)
AR (1) AR025962A1 (es)
AT (1) ATE258554T1 (es)
AU (1) AU779197B2 (es)
BR (1) BR0014818A (es)
CA (1) CA2382919C (es)
CO (1) CO5251378A1 (es)
CZ (1) CZ20021210A3 (es)
DE (1) DE50005155D1 (es)
DK (1) DK1218382T3 (es)
ES (1) ES2213611T3 (es)
HK (1) HK1047747B (es)
HU (1) HUP0203052A3 (es)
NO (1) NO322754B1 (es)
NZ (2) NZ518439A (es)
PE (1) PE20010634A1 (es)
PL (1) PL355206A1 (es)
PT (1) PT1218382E (es)
RU (1) RU2264402C2 (es)
SK (1) SK286788B6 (es)
UY (1) UY26372A1 (es)
WO (1) WO2001027111A2 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU2002224927A1 (en) * 2000-12-13 2002-06-24 Basf Aktiengesellschaft Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
DE102004021716A1 (de) * 2004-04-30 2005-12-01 Grünenthal GmbH Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
DE602005013085D1 (de) * 2004-06-09 2009-04-16 Oncalis Ag Proteinkinaseinhibitoren
WO2006131003A1 (en) * 2005-06-09 2006-12-14 Oncalis Ag Angiogenesis inhibitors
US7923041B2 (en) * 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
CA2602444C (en) * 2005-03-23 2013-03-19 F.Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pyrimidine derivatives as mglur2 antagonists
AU2006247118A1 (en) * 2005-05-20 2006-11-23 Array Biopharma Inc. Raf inhibitor compounds and methods of use thereof
JP2009507032A (ja) 2005-09-02 2009-02-19 アボット・ラボラトリーズ 新規なイミダゾ系複素環
EP1845098A1 (en) * 2006-03-29 2007-10-17 Ferrer Internacional, S.A. Imidazo[1,2-b]pyridazines, their processes of preparation and their use as GABA receptor ligands
AU2007267121A1 (en) * 2006-05-31 2007-12-06 Galapagos N.V. Triazolopyrazine compounds useful for the treatment of degenerative & inflammatory diseases
US8227603B2 (en) * 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US20100173930A1 (en) * 2006-08-01 2010-07-08 Alex Muci Certain Chemical Entities, Compositions and Methods
US8299248B2 (en) * 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
EP2995619B1 (en) * 2006-08-02 2019-09-25 Cytokinetics, Inc. Certain chemical entities comprising imidazopyrimidines, compositions and methods
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
US7851484B2 (en) * 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
GB0708188D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
PT2266990E (pt) * 2008-04-15 2012-12-27 Eisai R&D Man Co Ltd Composto de 3-fenilpirazolo[5,1-b]tiazole
EP2312948A4 (en) * 2008-07-10 2012-03-21 Southern Res Inst 5-CHINOLINONE AND IMIDAZOPYRIDINE COMPOUNDS AND THEIR USE
WO2010032195A1 (en) * 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
MX2011005886A (es) 2008-12-05 2011-07-28 Inviragen Inc Composiciones, métodos y usos para inducir el crecimiento viral.
AR078521A1 (es) * 2009-10-08 2011-11-16 Eisai R&D Man Co Ltd Compuesto pirazolotiazol
KR101951220B1 (ko) 2011-07-13 2019-02-22 싸이토키네틱스, 인코포레이티드 조합 als 치료법
KR20150082308A (ko) 2012-11-14 2015-07-15 에프. 호프만-라 로슈 아게 이미다조피리딘 유도체
MX358342B (es) * 2013-03-14 2018-08-15 Galapagos Nv Compuestos y composiciones farmaceuticas de los mismos para el tratamiento de trastornos inflamatorios.
WO2017160922A1 (en) 2016-03-16 2017-09-21 Kalyra Pharmaceuticals, Inc. Analgesic compounds
EP3615532A4 (en) * 2017-04-28 2020-11-18 Dana Farber Cancer Institute, Inc. TRIM33 INHIBITORS AND METHOD OF USE
EP3692052A4 (en) * 2017-10-04 2021-03-17 Dana Farber Cancer Institute, Inc. INHIBITION BY SMALL MOLECULES OF THE TRANSCRIPTION FACTOR SALL4 AND ITS USES

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
EP0266890A1 (en) * 1986-10-07 1988-05-11 Yamanouchi Pharmaceutical Co. Ltd. Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them
TW274551B (es) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
DE4327027A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Imidazoazine
US6020342A (en) * 1995-04-21 2000-02-01 Shinnippon Pharmaceutical, Inc. Fused imidazo[1,2-A]pyridines
AU2001270297A1 (en) * 2000-06-30 2002-01-14 Neurogen Corporation 2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands

Also Published As

Publication number Publication date
CZ20021210A3 (cs) 2002-08-14
HK1047747A1 (en) 2003-03-07
PT1218382E (pt) 2004-06-30
US6638933B2 (en) 2003-10-28
AU779197B2 (en) 2005-01-13
KR100756592B1 (ko) 2007-09-10
AU7777100A (en) 2001-04-23
CN1257169C (zh) 2006-05-24
HUP0203052A3 (en) 2004-06-28
EP1218382B1 (de) 2004-01-28
KR20020038805A (ko) 2002-05-23
NO20021565L (no) 2002-05-27
ATE258554T1 (de) 2004-02-15
NO322754B1 (no) 2006-12-04
EP1218382A2 (de) 2002-07-03
RU2264402C2 (ru) 2005-11-20
AR025962A1 (es) 2002-12-26
HK1047747B (zh) 2004-12-03
WO2001027111A2 (de) 2001-04-19
ES2213611T3 (es) 2004-09-01
US20030018032A1 (en) 2003-01-23
NZ518439A (en) 2003-10-31
NZ518390A (en) 2003-10-31
NO20021565D0 (no) 2002-04-03
HUP0203052A2 (hu) 2003-01-28
JP2003511451A (ja) 2003-03-25
CO5251378A1 (es) 2003-02-28
WO2001027111A3 (de) 2001-06-14
SK286788B6 (sk) 2009-05-07
SK4362002A3 (en) 2002-08-06
PL355206A1 (en) 2004-04-05
PE20010634A1 (es) 2001-07-07
DE50005155D1 (de) 2004-03-04
UY26372A1 (es) 2000-12-29
CA2382919A1 (en) 2001-04-19
CA2382919C (en) 2008-12-09
CN1391573A (zh) 2003-01-15
BR0014818A (pt) 2002-06-18

Similar Documents

Publication Publication Date Title
DK1218382T3 (da) Bicykliske imidazo-3-ylaminderivater
IS2116B (is) 4-fenyl-pyridin afleiður
NO20021077L (no) Amino-triazolopyridin-derivater
ATE263748T1 (de) Admantan-derivate
ATE293104T1 (de) Thiazolylamid-derivate
DE50015443D1 (de) Bicyclische imidazo-5-yl-aminderivate
EE200100613A (et) 13-metüülerütromütsiini derivaadid
DK1187814T3 (da) 5-phenyl-pyrimidinderivater
NO20021803D0 (no) Isoksazolkarboksamid-derivater
ATE257148T1 (de) Propargyletherderivate
PT1154988E (pt) Derivados de mevinolina
ATE374747T1 (de) Monofluoralkylderivate
PT1187815E (pt) Derivados de 4-fenil-pirimidina
DK1218340T3 (da) 4-hydroxybiphenylhydrazid-derivater
ATE293592T1 (de) Resorcinderivate
PT1194401E (pt) Derivados de diacil-hidrazina
PT1088818E (pt) Derivados de quinolin-4-ilo
NO20020212L (no) 3-amino-2-benzyl-1-fenyl-propanderivater
DE60025348D1 (de) Ethansulfonyl-piperidin-derivate
DK1178984T3 (da) 1-trifluormethyl-4-hydroxy-7-piperidinylaminomethylchroman-derivater
ATE269328T1 (de) 1-cycloalkylpyrazolyl-benzoyl-derivate