DK1194580T3 - In vitro-rekonstruktion af segmenterede negativ-strengede RNA-virus - Google Patents
In vitro-rekonstruktion af segmenterede negativ-strengede RNA-virusInfo
- Publication number
- DK1194580T3 DK1194580T3 DK00946097T DK00946097T DK1194580T3 DK 1194580 T3 DK1194580 T3 DK 1194580T3 DK 00946097 T DK00946097 T DK 00946097T DK 00946097 T DK00946097 T DK 00946097T DK 1194580 T3 DK1194580 T3 DK 1194580T3
- Authority
- DK
- Denmark
- Prior art keywords
- segmented negative
- stranded rna
- rna viruses
- vitro reconstruction
- reconstruction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14364599P | 1999-07-14 | 1999-07-14 | |
GBGB9916794.2A GB9916794D0 (en) | 1999-07-16 | 1999-07-16 | In vitro virus reconstitution |
PCT/GB2000/002710 WO2001004333A1 (en) | 1999-07-14 | 2000-07-14 | In vitro reconstitution of segmented negative-strand rna viruses |
Publications (2)
Publication Number | Publication Date |
---|---|
DK1194580T3 true DK1194580T3 (da) | 2007-04-10 |
DK1194580T4 DK1194580T4 (da) | 2011-01-03 |
Family
ID=26315773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00946097.3T DK1194580T4 (da) | 1999-07-14 | 2000-07-14 | In-vitro rekonstitution af segmenterede negativstrengede RNA-virus |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1194580B2 (da) |
AT (1) | ATE353370T1 (da) |
AU (1) | AU5998400A (da) |
CA (1) | CA2379012C (da) |
CY (2) | CY1106404T1 (da) |
DE (5) | DE122007000070I1 (da) |
DK (1) | DK1194580T4 (da) |
ES (1) | ES2278621T5 (da) |
FR (1) | FR08C0046I2 (da) |
LU (1) | LU91367I2 (da) |
NL (4) | NL300294I2 (da) |
WO (1) | WO2001004333A1 (da) |
Families Citing this family (68)
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AU771110B2 (en) | 1998-06-12 | 2004-03-11 | Mount Sinai School Of Medicine Of The City University Of New York, The | Novel methods and interferon deficient substrates for the propagation of viruses |
AU2002309133A1 (en) * | 2001-04-17 | 2002-10-28 | Institut Pasteur | Recombinant segmented negative strand virus with a duplicated 3' noncoding flanking sequence, and therapeutic compositions containing the same |
US7226774B2 (en) | 2002-02-13 | 2007-06-05 | Wisconsin Alumni Research Foundation | Signal for packaging of influenza virus vectors |
FR2866031B1 (fr) * | 2004-02-11 | 2012-10-19 | David Francois Joseph Millet | Chimere de virus pathogene emergent, medicament la contenant et utilisation en therapie antivirale |
DE202005022108U1 (de) | 2004-03-09 | 2013-11-12 | Novartis Vaccines And Diagnostics, Inc. | Influenza-Virus-Impfstoffe |
CA2610632C (en) | 2004-06-01 | 2022-10-04 | Mount Sinai School Of Medicine Of New York University | Genetically engineered swine influenza virus and uses thereof |
US7959930B2 (en) | 2004-12-24 | 2011-06-14 | Abbott Biologicals B.V. | Rescue of influenza virus |
EP1855713B1 (en) | 2005-02-15 | 2016-04-27 | Mount Sinai School of Medicine | Genetically engineered equine influenza virus and uses thereof |
US11865172B2 (en) | 2005-04-21 | 2024-01-09 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
US7959929B2 (en) | 2005-04-21 | 2011-06-14 | University Of Florida Research Foundation, Inc. | Materials and methods for respiratory disease control in canines |
BRPI0612268A2 (pt) | 2005-06-21 | 2009-01-27 | Medimmune Vaccines Inc | Ácido nucleico isolado, vetor de expressço, mÉtodos para produzir um rna genâmico da influenza, para produzir um vÍrus da influenza recombinante, para gerar um vÍrus de rna segmentado de filamento negativo recombinante nas cÉlulas caninas cultivadas e para gerar partÍculas virais da influenza infecciosa em cÉlulas caninas cultivadas, cÉlula, e, vÍrus |
US7790434B2 (en) | 2005-06-21 | 2010-09-07 | Medimmune, Llc | Methods and compositions for expressing negative-sense viral RNA in canine cells |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
US20090304742A1 (en) | 2005-11-04 | 2009-12-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccines with reduced amount of emulsion adjuvant |
NZ568211A (en) | 2005-11-04 | 2011-11-25 | Novartis Vaccines & Diagnostic | Influenza vaccines including combinations of particulate adjuvants and immunopotentiators |
PT2368572T (pt) | 2005-11-04 | 2020-06-16 | Seqirus Uk Ltd | Vacinas com adjuvante dotadas de antigénios não-virião preparados a partir de vírus da gripe cultivado em cultura celular |
CA2628424A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted influenza vaccines including cytokine-inducing agents |
WO2007052061A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Emulsions with free aqueous-phase surfactant as adjuvants for split influenza vaccines |
AP2911A (en) | 2005-12-02 | 2014-05-31 | Sinai School Medicine | Chimeric Viruses presenting non-native surface proteins and uses thereof |
KR20080089663A (ko) | 2006-01-27 | 2008-10-07 | 노바티스 백신즈 앤드 다이아그노스틱스 게엠베하 운트 콤파니 카게 | 적혈구응집소 및 기질 단백질을 함유한 인플루엔자 백신 |
AU2007231027B2 (en) | 2006-03-24 | 2013-10-03 | Novartis Influenza Vaccines Marburg Gmbh | Storage of influenza vaccines without refrigeration |
WO2007124327A2 (en) * | 2006-04-19 | 2007-11-01 | Medimmune Llc. | Methods and compositions for expressing negative-sense viral rna in canine cells |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
AU2007297178B2 (en) | 2006-09-11 | 2014-07-24 | Novartis Ag | Making influenza virus vaccines without using eggs |
WO2008068631A2 (en) | 2006-12-06 | 2008-06-12 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
US8597661B2 (en) | 2007-05-04 | 2013-12-03 | Wisconsin Alumni Research Foundation | Neuraminidase-deficient live influenza vaccines |
US8043856B2 (en) | 2007-06-14 | 2011-10-25 | Wisconsin Alumni Research Foundation | Adenoviral vectors for influenza virus production |
EP2045323A1 (en) * | 2007-10-05 | 2009-04-08 | Avir Green Hills Biotechnology Research Development Trade Ag | Linear expression constructs for production of influenza virus particles |
NZ582595A (en) | 2007-06-27 | 2012-07-27 | Novartis Ag | Low-additive influenza vaccines |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
NZ587798A (en) | 2008-03-18 | 2013-06-28 | Novartis Ag | Improvements in the preparation of influenza virus vaccine antigens utilising a phosphate buffer |
EP2233568A1 (en) | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
EP2987856B1 (en) | 2009-02-05 | 2018-07-25 | Icahn School of Medicine at Mount Sinai | Chimeric newcastle disease viruses and uses thereof |
CN102307590A (zh) | 2009-02-10 | 2012-01-04 | 诺华有限公司 | 具有减少量的角鲨烯的流感疫苗 |
CA2752039A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
WO2010092477A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccines with increased amounts of h3 antigen |
CA2787099A1 (en) | 2009-03-30 | 2010-10-14 | Anice C. Lowen | Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof |
DE102010018462A1 (de) | 2009-04-27 | 2011-04-07 | Novartis Ag | Impfstoffe zum Schutz gegen Influenza |
WO2011014504A1 (en) | 2009-07-27 | 2011-02-03 | Mount Sinai School Of Medicine Of New York University | Recombinant influenza virus vectors and uses thereof |
CA2805505C (en) | 2009-07-30 | 2021-08-03 | Mount Sinai School Of Medecine | Chimeric influenza viruses having reduced ability to reassort with other influenza viruses and uses thereof |
US20120237536A1 (en) | 2009-09-10 | 2012-09-20 | Novartis | Combination vaccines against respiratory tract diseases |
CA2792537A1 (en) | 2010-03-30 | 2011-10-06 | Mount Sinai School Of Medicine | Influenza virus vaccines and uses thereof |
EA201201620A1 (ru) | 2010-06-02 | 2013-07-30 | Авир Грин Хилз Байотекнолоджи Рисерч Дивелопмент Трейд Аг | Способ получения рнк-вируса |
EP2747778B1 (en) | 2011-08-26 | 2017-12-06 | Wisconsin Alumni Research Foundation | Influenza viruses with mutant pb2 gene segment as live attenuated vaccines |
EP2758075B1 (en) | 2011-09-20 | 2023-05-03 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
US20140248320A1 (en) | 2011-10-20 | 2014-09-04 | Novartis Ag | Adjuvanted influenza b virus vaccines for pediatric priming |
EP2708552A1 (en) | 2012-09-12 | 2014-03-19 | Medizinische Universität Wien | Influenza virus |
GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
NZ627796A (en) | 2012-12-18 | 2017-07-28 | Icahn School Med Mount Sinai | Influenza virus vaccines and uses thereof |
BR112015017420A2 (pt) * | 2013-01-23 | 2017-07-11 | Novartis Ag | recombinação de vírus influenza |
US20140274806A1 (en) | 2013-03-15 | 2014-09-18 | Synthetic Genomics Vaccines | Influenza virus reassortment |
WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
MX2015011886A (es) | 2013-03-14 | 2016-05-31 | Icahn School Med Mount Sinai | Virus de la enfermedad de newcastle y usos de los mismos. |
JP6857498B2 (ja) | 2014-02-27 | 2021-04-14 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 癌を処置するための併用方法 |
WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
CL2014003146A1 (es) * | 2014-11-20 | 2015-06-12 | Univ Santiago Chile | Método para producir virus arn monocatenario negativo; plásmido recombinante funcional en células animales, que consta de un esqueleto pss-urg; método de obtención de partículas virales; y uso para expresar arn, proteínas autógenas o exógenas al virus. |
JP2018504412A (ja) | 2015-01-23 | 2018-02-15 | アイカーン スクール オブ メディシン アット マウント サイナイ | インフルエンザウイルスワクチン接種レジメン |
EP3261664A1 (en) | 2015-02-26 | 2018-01-03 | Boehringer Ingelheim Vetmedica GmbH | Bivalent swine influenza virus vaccine |
WO2016207853A2 (en) | 2015-06-26 | 2016-12-29 | Seqirus UK Limited | Antigenically matched influenza vaccines |
WO2017005880A1 (en) | 2015-07-07 | 2017-01-12 | Seqirus UK Limited | Influenza potency assays |
WO2017040203A1 (en) | 2015-08-28 | 2017-03-09 | Yoshihiro Kawaoka | Generation of infectious influenza viruses from virus-like particles |
US11266734B2 (en) | 2016-06-15 | 2022-03-08 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
WO2018187706A2 (en) | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
JOP20190256A1 (ar) | 2017-05-12 | 2019-10-28 | Icahn School Med Mount Sinai | فيروسات داء نيوكاسل واستخداماتها |
US11851648B2 (en) | 2019-02-08 | 2023-12-26 | Wisconsin Alumni Research Foundation (Warf) | Humanized cell line |
EP4022046A2 (en) | 2019-08-27 | 2022-07-06 | Wisconsin Alumni Research Foundation (WARF) | Recombinant influenza viruses with stabilized ha for replication in eggs |
CN111363727B (zh) * | 2020-01-20 | 2021-09-24 | 武汉大学 | 携带幽门螺杆菌的重组流感病毒、宿主细胞及其制备方法与应用 |
EP3896077A1 (en) | 2020-04-16 | 2021-10-20 | Österreichische Agentur für Gesundheit und Ernährungssicherheit GmbH | Influenza virus-like particles (vlps) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840520A (en) * | 1989-08-28 | 1998-11-24 | Aviron | Recombinant negative strand RNA virus expression systems |
DK1185615T3 (da) * | 1999-04-06 | 2007-11-05 | Wisconsin Alumni Res Found | Rekombinante influenzavirus til vacciner og genterapi |
-
2000
- 2000-07-14 DE DE200712000070 patent/DE122007000070I1/de active Pending
- 2000-07-14 AT AT00946097T patent/ATE353370T1/de active
- 2000-07-14 DE DE122008000057C patent/DE122008000057I1/de active Pending
- 2000-07-14 DK DK00946097.3T patent/DK1194580T4/da active
- 2000-07-14 EP EP00946097A patent/EP1194580B2/en not_active Expired - Lifetime
- 2000-07-14 DE DE60033284.5T patent/DE60033284T3/de not_active Expired - Lifetime
- 2000-07-14 DE DE122008000056C patent/DE122008000056I1/de active Pending
- 2000-07-14 CA CA2379012A patent/CA2379012C/en not_active Expired - Lifetime
- 2000-07-14 AU AU59984/00A patent/AU5998400A/en not_active Abandoned
- 2000-07-14 WO PCT/GB2000/002710 patent/WO2001004333A1/en active IP Right Grant
- 2000-07-14 DE DE200712000061 patent/DE122007000061I2/de active Active
- 2000-07-14 ES ES00946097T patent/ES2278621T5/es not_active Expired - Lifetime
-
2007
- 2007-03-20 CY CY20071100397T patent/CY1106404T1/el unknown
- 2007-09-21 LU LU91367C patent/LU91367I2/fr unknown
- 2007-09-21 NL NL300294C patent/NL300294I2/nl unknown
- 2007-09-21 NL NL300301C patent/NL300301I2/nl unknown
- 2007-09-21 CY CY200700023C patent/CY2007023I1/el unknown
-
2008
- 2008-11-13 NL NL300369C patent/NL300369I1/nl unknown
- 2008-11-13 FR FR08C0046C patent/FR08C0046I2/fr active Active
- 2008-11-13 NL NL300368C patent/NL300368I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
NL300368I2 (nl) | 2017-08-03 |
NL300368I1 (nl) | 2009-01-05 |
NL300294I2 (nl) | 2008-10-01 |
DK1194580T4 (da) | 2011-01-03 |
FR08C0046I2 (fr) | 2011-11-25 |
CY2007023I2 (el) | 2009-11-04 |
DE122007000061I2 (de) | 2011-07-21 |
NL300301I1 (nl) | 2008-01-02 |
ES2278621T3 (es) | 2007-08-16 |
NL300369I1 (nl) | 2009-01-05 |
DE60033284T2 (de) | 2007-10-25 |
EP1194580B2 (en) | 2010-08-25 |
DE122008000057I1 (de) | 2009-04-09 |
NL300294I1 (nl) | 2007-12-03 |
LU91367I2 (fr) | 2007-11-21 |
AU5998400A (en) | 2001-01-30 |
DE122007000061I1 (de) | 2007-12-20 |
CY1106404T1 (el) | 2010-07-28 |
ES2278621T5 (es) | 2011-02-02 |
CA2379012C (en) | 2013-07-02 |
EP1194580A1 (en) | 2002-04-10 |
DE122007000070I1 (de) | 2008-01-31 |
WO2001004333A1 (en) | 2001-01-18 |
ATE353370T1 (de) | 2007-02-15 |
DE60033284T3 (de) | 2014-10-30 |
FR08C0046I1 (fr) | 2009-01-02 |
DE122008000056I1 (de) | 2009-04-09 |
NL300301I2 (nl) | 2008-10-01 |
EP1194580B1 (en) | 2007-02-07 |
DE60033284D1 (de) | 2007-03-22 |
CA2379012A1 (en) | 2001-01-18 |
CY2007023I1 (el) | 2009-11-04 |
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