DK1079857T3 - Meningitidis B/C-kombinationsvacciner - Google Patents

Meningitidis B/C-kombinationsvacciner

Info

Publication number: DK1079857T3
Authority: DK; Denmark
Prior art keywords: meningitidis; combination vaccines; serogroup; combination; oligosaccharides
Prior art date: 1998-05-29

Application number

DK99926046T

Other languages

English (en)

Inventor

Dan M Granoff

Ingeborg S Aaberge

Bjorn Haneberg

Johan Holst

Howard Raff

Original Assignee

Novartis Vaccines & Diagnostic

Statens Inst For Folkehelse

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-29

Filing date

1999-05-28

Publication date

2007-01-29

1999-05-28 Application filed by Novartis Vaccines & Diagnostic, Statens Inst For Folkehelse filed Critical Novartis Vaccines & Diagnostic

2007-01-29 Application granted granted Critical

2007-01-29 Publication of DK1079857T3 publication Critical patent/DK1079857T3/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Fats And Perfumes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Beans For Foods Or Fodder (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK99926046T 1998-05-29 1999-05-28 Meningitidis B/C-kombinationsvacciner DK1079857T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US8735198P	1998-05-29	1998-05-29
US10644698P	1998-10-30	1998-10-30
PCT/US1999/011977 WO1999061053A1 (en)	1998-05-29	1999-05-28	Combination meningitidis b/c vaccines

Publications (1)

Publication Number	Publication Date
DK1079857T3 true DK1079857T3 (da)	2007-01-29

Family

ID=26776879

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99926046T DK1079857T3 (da)	1998-05-29	1999-05-28	Meningitidis B/C-kombinationsvacciner

Country Status (15)

Country	Link
US (1)	US8007815B1 (da)
EP (2)	EP2796148A3 (da)
JP (2)	JP5074644B2 (da)
AT (1)	ATE346609T1 (da)
AU (2)	AU761495B2 (da)
BR (1)	BR9910749A (da)
CA (1)	CA2332963C (da)
CY (1)	CY1107550T1 (da)
DE (1)	DE69934225T2 (da)
DK (1)	DK1079857T3 (da)
ES (2)	ES2278446T3 (da)
HK (1)	HK1034460A1 (da)
NZ (1)	NZ508771A (da)
PT (2)	PT1079857E (da)
WO (1)	WO1999061053A1 (da)

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EP1860192A1 (en)	1996-09-17	2007-11-28	Novartis Vaccines and Diagnostics, Inc.	Compositions and methods for treating intracellular diseases
ES2278446T3 (es)	1998-05-29	2007-08-01	Novartis Vaccines And Diagnostics, Inc.	Vacunas combinadas b/c contra la meningitis.
AU783894B2 (en)	1999-05-19	2005-12-22	Novartis Vaccines And Diagnostics S.R.L.	Combination neisserial compositions
GB9928196D0 (en) *	1999-11-29	2000-01-26	Chiron Spa	Combinations of B, C and other antigens
DK2289545T3 (da)	2000-01-17	2016-09-05	Glaxosmithkline Biologicals Sa	Suppleret OMV-vaccine mod meningococcus
CA2416137C (en)	2000-07-27	2013-01-29	Dan Granoff	Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0115176D0 (en)	2001-06-20	2001-08-15	Chiron Spa	Capular polysaccharide solubilisation and combination vaccines
JP4592284B2 (ja)	2001-07-27	2010-12-01	カイロンソチエタアレスポンサビリタリミタータ	髄膜炎菌付着因子
MX339524B (es)	2001-10-11	2016-05-30	Wyeth Corp	Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0316560D0 (en)	2003-07-15	2003-08-20	Chiron Srl	Vesicle filtration
ES2397923T3 (es)	2003-10-02	2013-03-12	Novartis Ag	Vacunas líquidas para múltiples serogrupos meningocócicos
GB0419627D0 (en)	2004-09-03	2004-10-06	Chiron Srl	Immunogenic bacterial vesicles with outer membrane proteins
GB0424092D0 (en)	2004-10-29	2004-12-01	Chiron Srl	Immunogenic bacterial vesicles with outer membrane proteins
EP2682126B1 (en)	2005-01-27	2016-11-23	Children's Hospital & Research Center at Oakland	GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
PT2200642E (pt) *	2007-10-19	2012-05-30	Novartis Ag	Formulações de vacinas meningocócicas
JP2013502918A (ja) *	2009-08-27	2013-01-31	ノバルティスアーゲー	髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
RU2580620C2 (ru)	2010-08-23	2016-04-10	ВАЙЕТ ЭлЭлСи	СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086
PE20140173A1 (es)	2010-09-10	2014-02-20	Wyeth Llc	Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis
GB201015132D0 (en) *	2010-09-10	2010-10-27	Univ Bristol	Vaccine composition
AU2011300418B2 (en)	2010-09-10	2016-05-12	Glaxosmithkline Biologicals Sa	Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom
SA115360586B1 (ar)	2012-03-09	2017-04-12	فايزر انك	تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
MY198910A (en)	2012-03-09	2023-10-02	Pfizer	Neisseria meningitidis compositions and methods thereof
RU2015106930A (ru) *	2012-09-06	2016-10-20	Новартис Аг	Комбинированные вакцины с менингококком серогруппы в и к/д/с
RU2662970C2 (ru)	2012-09-18	2018-07-31	Новартис Аг	Везикулы наружной мембраны
EP2964665B1 (en)	2013-03-08	2018-08-01	Pfizer Inc	Immunogenic fusion polypeptides
MX369534B (es)	2013-09-08	2019-11-11	Pfizer	Composiciones de neisseria meningitidis y sus metodos.
CN107249626A (zh)	2015-02-19	2017-10-13	辉瑞大药厂	脑膜炎奈瑟球菌组合物及其方法
SG11201906519RA (en)	2017-01-31	2019-08-27	Pfizer	Neisseria meningitidis compositions and methods thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2848965A1 (de)	1978-11-11	1980-05-22	Behringwerke Ag	Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
US4707543A (en) *	1985-09-17	1987-11-17	The United States Of America As Represented By The Secretary Of The Army	Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines
US7118757B1 (en) *	1988-12-19	2006-10-10	Wyeth Holdings Corporation	Meningococcal class 1 outer-membrane protein vaccine
AU640118B2 (en) *	1988-12-19	1993-08-19	De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur	Meningococcal class 1 outer-membrane protein vaccine
JPH0832638B2 (ja)	1989-05-25	1996-03-29	カイロンコーポレイション	サブミクロン油滴乳剤を含んで成るアジュバント製剤
DE69423383T2 (de)	1993-05-13	2000-08-24	American Cyanamid Co	Herstellung und Verwendungen von LOS-verminderten Aussenmembran-Proteinen von Gram-negativen Kokken
ES2128055T3 (es)	1994-04-20	1999-05-01	Us Army	Vacuna contra infecciones de bacterias gram-negativas.
US6180111B1 (en)	1995-05-18	2001-01-30	University Of Maryland	Vaccine delivery system
PT854729E (pt) *	1995-09-18	2004-08-31	Us Army Med Res Mat Com Usamrm	Metodos melhorados para a producao de vacinas de subunidade multivalentes de proteossomas complexados nao covalentemente
DE19601754A1 (de) *	1996-01-19	1997-07-24	Hoechst Ag	Dictyocaulus viviparus Antigen zur Diagnose des Lungenwurmbefalls und zur Vakzinierung
US5846735A (en) *	1996-04-18	1998-12-08	University Of Iowa Research Foundation	Hepatitis C virus Fc-binding function
DE69708318T3 (de) *	1996-08-27	2006-11-16	Novartis Vaccines and Diagnostics, Inc., Emeryville	Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
US6558677B2 (en) *	1996-10-15	2003-05-06	Wendell D. Zollinger	Vaccine against gram negative bacteria
EP0994723A1 (en) *	1997-06-24	2000-04-26	Chiron Corporation	Methods of immunizing adults using anti-meningococcal vaccine compositions
BR9811475A (pt) *	1997-07-17	2000-08-15	North American Vaccine Inc	Conjugados imunogênicos compreendendo uma porina meningocóccica de grupo b e um polissacarìdeo de h. influenzae
GB9727262D0 (en)	1997-12-24	1998-02-25	Smithkline Beecham Biolog	Vaccine
ES2278446T3 (es)	1998-05-29	2007-08-01	Novartis Vaccines And Diagnostics, Inc.	Vacunas combinadas b/c contra la meningitis.
AU1917501A (en)	1999-11-12	2001-06-06	University Of Iowa Research Foundation, The	Control of neisserial membrane synthesis
CA2416137C (en)	2000-07-27	2013-01-29	Dan Granoff	Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0220194D0 (en)	2002-08-30	2002-10-09	Chiron Spa	Improved vesicles
WO2004067030A2 (en)	2003-01-30	2004-08-12	Chiron Srl	Injectable vaccines against multiple meningococcal serogroups
GB0316560D0 (en)	2003-07-15	2003-08-20	Chiron Srl	Vesicle filtration
ES2397923T3 (es)	2003-10-02	2013-03-12	Novartis Ag	Vacunas líquidas para múltiples serogrupos meningocócicos

1999
- 1999-05-28 ES ES99926046T patent/ES2278446T3/es not_active Expired - Lifetime
- 1999-05-28 PT PT99926046T patent/PT1079857E/pt unknown
- 1999-05-28 WO PCT/US1999/011977 patent/WO1999061053A1/en active IP Right Grant
- 1999-05-28 DK DK99926046T patent/DK1079857T3/da active
- 1999-05-28 DE DE69934225T patent/DE69934225T2/de not_active Expired - Lifetime
- 1999-05-28 NZ NZ508771A patent/NZ508771A/en not_active IP Right Cessation
- 1999-05-28 EP EP20140169154 patent/EP2796148A3/en not_active Withdrawn
- 1999-05-28 BR BR9910749-0A patent/BR9910749A/pt not_active Application Discontinuation
- 1999-05-28 JP JP2000550512A patent/JP5074644B2/ja not_active Expired - Fee Related
- 1999-05-28 CA CA2332963A patent/CA2332963C/en not_active Expired - Fee Related
- 1999-05-28 PT PT60766474T patent/PT1741443E/pt unknown
- 1999-05-28 EP EP99926046A patent/EP1079857B1/en not_active Expired - Lifetime
- 1999-05-28 AU AU42215/99A patent/AU761495B2/en not_active Revoked
- 1999-05-28 ES ES06076647.4T patent/ES2485940T3/es not_active Expired - Lifetime
- 1999-05-28 AT AT99926046T patent/ATE346609T1/de active
- 1999-05-28 US US09/701,453 patent/US8007815B1/en not_active Expired - Fee Related
2001
- 2001-07-20 HK HK01105114A patent/HK1034460A1/xx not_active IP Right Cessation
2003
- 2003-09-02 AU AU2003244518A patent/AU2003244518A1/en not_active Withdrawn
2007
- 2007-01-31 CY CY20071100128T patent/CY1107550T1/el unknown
2009
- 2009-09-24 JP JP2009219818A patent/JP2009292851A/ja active Pending

Also Published As

Publication number	Publication date
EP2796148A2 (en)	2014-10-29
US8007815B1 (en)	2011-08-30
WO1999061053A1 (en)	1999-12-02
ES2278446T3 (es)	2007-08-01
JP5074644B2 (ja)	2012-11-14
DE69934225D1 (de)	2007-01-11
EP1079857A1 (en)	2001-03-07
CY1107550T1 (el)	2013-03-13
DE69934225T2 (de)	2007-09-27
JP2009292851A (ja)	2009-12-17
ES2485940T3 (es)	2014-08-14
NZ508771A (en)	2003-08-29
HK1034460A1 (en)	2001-10-26
ATE346609T1 (de)	2006-12-15
PT1079857E (pt)	2007-02-28
AU2003244518A1 (en)	2003-09-25
CA2332963A1 (en)	1999-12-02
JP2002516292A (ja)	2002-06-04
EP1079857B1 (en)	2006-11-29
AU4221599A (en)	1999-12-13
EP2796148A3 (en)	2015-02-25
CA2332963C (en)	2013-07-23
AU761495B2 (en)	2003-06-05
BR9910749A (pt)	2001-02-13
PT1741443E (pt)	2014-07-31

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CY1107550T1 (el)	2013-03-13	Συνδυαστικα εμβολια μηνιγγιτιδας b/c
NO20022531L (no)	2002-07-12	Vaksine for forebyggelse og behandling av Alzheimer- og amyloidrelaterte sykdommer
ATE474594T1 (de)	2010-08-15	Neisseria meningitidis kombinationimpfstoffe
DK1382348T3 (da)	2006-03-13	Polynukleotidvaccineformulering, især til behandling af bovin luftvejssygdom
HUP0302636A2 (hu)	2003-11-28	Hasított burkolt víruskészítmény
ATE347376T1 (de)	2006-12-15	Behandlung von allergien
EE200100645A (et)	2003-02-17	Amüloidogeense haiguse preventsioon ja ravi
DE60027890D1 (de)	2006-06-14	Streptococcus pneumoniae proteine und impfstoffe
CY1106092T1 (el)	2011-06-08	Χρηση του μακρου μοριου της πεντραξινης ρτχ3 για τη θepαπεια ασθενειων που προκαλουνται απο μια μεταβαλλομενη ενepγοποιηση του αυξητικου παραγοντα fgf-2
PT998287E (pt)	2003-09-30	Utilizacao de levobupivacaina
HUP0300559A2 (hu)	2003-06-28	A trombopoietin receptort moduláló peptidek
DK1265577T3 (da)	2004-03-15	Medicinsk eller dentalmedicinsk behandlingsstol
EP1741443A3 (en)	2007-02-28	Combination meningitidis B/C vaccines
ATE334697T1 (de)	2006-08-15	Boviner atmungs- und darmcoronavirus als impfstoff
DE60042489D1 (de)	2009-08-13	Impfstoff gegen neisseria infektion
DE69824794D1 (de)	2004-08-05	Streptococcus equi Impfstoff
ITTO20020284A1 (it)	2003-09-29	Procedimento per la sterilizzazione e la neutralizzazione di odori dell'aria.
RU99102457A (ru)	2000-12-10	Способ профилактики дифтерии на крайнем севере
NZ523676A (en)	2003-03-28	Use of cetyl myristate and cetyl palmitate to treat irritable bowel syndrome or irritable bowel disease
ES1030556Y (es)	1996-02-16	Unidad odontologica de atencion al paciente.