DK1049672T3 - Azetidincarboxamid-derivater til behandling af CNS-lidelser - Google Patents

Azetidincarboxamid-derivater til behandling af CNS-lidelser

Info

Publication number
DK1049672T3
DK1049672T3 DK99902658T DK99902658T DK1049672T3 DK 1049672 T3 DK1049672 T3 DK 1049672T3 DK 99902658 T DK99902658 T DK 99902658T DK 99902658 T DK99902658 T DK 99902658T DK 1049672 T3 DK1049672 T3 DK 1049672T3
Authority
DK
Denmark
Prior art keywords
treatment
cns disorders
carboxamide derivatives
azetidine carboxamide
azetidine
Prior art date
Application number
DK99902658T
Other languages
English (en)
Inventor
David Reginald Adams
Corinna Dagmar Bodkin
Ian Anthony Cliffe
Howard Langham Mansell
Nathaniel Julius Monck
Robin Gerald Shepherd
Original Assignee
Vernalis Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9801500.1A external-priority patent/GB9801500D0/en
Priority claimed from GBGB9824457.7A external-priority patent/GB9824457D0/en
Application filed by Vernalis Res Ltd filed Critical Vernalis Res Ltd
Application granted granted Critical
Publication of DK1049672T3 publication Critical patent/DK1049672T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK99902658T 1998-01-23 1999-01-22 Azetidincarboxamid-derivater til behandling af CNS-lidelser DK1049672T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9801500.1A GB9801500D0 (en) 1998-01-23 1998-01-23 Chemical compounds - II
GBGB9824457.7A GB9824457D0 (en) 1998-11-06 1998-11-06 Chemical compounds II
PCT/GB1999/000219 WO1999037612A1 (en) 1998-01-23 1999-01-22 Azetidinecarboxamide derivatives for treating cns disorders

Publications (1)

Publication Number Publication Date
DK1049672T3 true DK1049672T3 (da) 2004-01-19

Family

ID=26313010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99902658T DK1049672T3 (da) 1998-01-23 1999-01-22 Azetidincarboxamid-derivater til behandling af CNS-lidelser

Country Status (10)

Country Link
US (1) US6403574B1 (da)
EP (1) EP1049672B1 (da)
JP (1) JP4542263B2 (da)
AT (1) ATE250027T1 (da)
AU (1) AU2287499A (da)
DE (1) DE69911373T2 (da)
DK (1) DK1049672T3 (da)
ES (1) ES2207171T3 (da)
PT (1) PT1049672E (da)
WO (1) WO1999037612A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917386D0 (en) * 1999-07-23 1999-09-22 Cerebrus Ltd Chemical compounds-II
JP2006525298A (ja) * 2003-05-01 2006-11-09 ヴァーナリス リサーチ リミテッド アゼチジンカルボキサミド誘導体及びcb1レセプター媒介障害の治療におけるその使用
KR20060017763A (ko) * 2003-05-01 2006-02-27 베르날리스 리서치 리미티드 치료에 사용하는 아제티딘카르복스아미드 유도체의 용도
US20070173486A1 (en) * 2003-05-01 2007-07-26 Vernalis Research Limited Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disordrs
US11141404B1 (en) 2020-11-18 2021-10-12 Anebulo Pharmaceuticals, Inc. Formulations and methods for treating acute cannabinoid overdose
WO2023064225A1 (en) 2021-10-11 2023-04-20 Anebulo Pharmaceuticals, Inc. Crystalline forms of a cannabinoid receptor type 1 (cb1) modulator and methods of use and preparation thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB872447A (en) * 1958-12-23 1961-07-12 Lepetit Spa 1-carbamyl-3-substituted azetidines
US4226861A (en) 1978-04-18 1980-10-07 A. H. Robins Company, Inc. N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
IL68699A (en) * 1982-08-19 1986-08-31 Robins Co Inc A H 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them
US4505907A (en) 1982-09-02 1985-03-19 A. H. Robins Company, Inc. N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
US4956359A (en) * 1985-02-28 1990-09-11 A. H. Robins Company, Inc. 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics
FI87559C (fi) * 1985-02-28 1993-01-25 Robins Co Inc A H Foerfarande foer framstaellning av aktiva 3-fenyloxiazetidinkarboxamider

Also Published As

Publication number Publication date
US6403574B1 (en) 2002-06-11
AU2287499A (en) 1999-08-09
WO1999037612A1 (en) 1999-07-29
PT1049672E (pt) 2004-02-27
EP1049672A1 (en) 2000-11-08
EP1049672B1 (en) 2003-09-17
DE69911373D1 (de) 2003-10-23
JP4542263B2 (ja) 2010-09-08
ATE250027T1 (de) 2003-10-15
JP2002501045A (ja) 2002-01-15
ES2207171T3 (es) 2004-05-16
DE69911373T2 (de) 2004-07-01

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