ATE250027T1 - Azetidincarboxamidderivate zur behandlung von zns-erkrankungen - Google Patents

Azetidincarboxamidderivate zur behandlung von zns-erkrankungen

Info

Publication number
ATE250027T1
ATE250027T1 AT99902658T AT99902658T ATE250027T1 AT E250027 T1 ATE250027 T1 AT E250027T1 AT 99902658 T AT99902658 T AT 99902658T AT 99902658 T AT99902658 T AT 99902658T AT E250027 T1 ATE250027 T1 AT E250027T1
Authority
AT
Austria
Prior art keywords
treatment
carboxamide derivatives
cns diseases
azetidine carboxamide
azetidine
Prior art date
Application number
AT99902658T
Other languages
English (en)
Inventor
Robin Gerald Shepherd
David Reginald Adams
Corinna Dagmar Bodkin
Ian Anthony Cliffe
Howard Langham Mansell
Nathaniel Julius Monck
Original Assignee
Vernalis Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9801500.1A external-priority patent/GB9801500D0/en
Priority claimed from GBGB9824457.7A external-priority patent/GB9824457D0/en
Application filed by Vernalis Res Ltd filed Critical Vernalis Res Ltd
Application granted granted Critical
Publication of ATE250027T1 publication Critical patent/ATE250027T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99902658T 1998-01-23 1999-01-22 Azetidincarboxamidderivate zur behandlung von zns-erkrankungen ATE250027T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9801500.1A GB9801500D0 (en) 1998-01-23 1998-01-23 Chemical compounds - II
GBGB9824457.7A GB9824457D0 (en) 1998-11-06 1998-11-06 Chemical compounds II
PCT/GB1999/000219 WO1999037612A1 (en) 1998-01-23 1999-01-22 Azetidinecarboxamide derivatives for treating cns disorders

Publications (1)

Publication Number Publication Date
ATE250027T1 true ATE250027T1 (de) 2003-10-15

Family

ID=26313010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99902658T ATE250027T1 (de) 1998-01-23 1999-01-22 Azetidincarboxamidderivate zur behandlung von zns-erkrankungen

Country Status (10)

Country Link
US (1) US6403574B1 (de)
EP (1) EP1049672B1 (de)
JP (1) JP4542263B2 (de)
AT (1) ATE250027T1 (de)
AU (1) AU2287499A (de)
DE (1) DE69911373T2 (de)
DK (1) DK1049672T3 (de)
ES (1) ES2207171T3 (de)
PT (1) PT1049672E (de)
WO (1) WO1999037612A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917386D0 (en) * 1999-07-23 1999-09-22 Cerebrus Ltd Chemical compounds-II
WO2004096794A1 (en) * 2003-05-01 2004-11-11 Vernalis Research Limited Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disordrs
US20060276452A1 (en) * 2003-05-01 2006-12-07 Vernalis Research Limited Use of azetidinecarboxamide derivatives in therapy
EA010583B1 (ru) 2003-05-01 2008-10-30 Вернэлис Рисёч Лимитед Производные азетидинкарбоксамида и их применение при лечении нарушений, опосредованных св1 рецепторами
US11141404B1 (en) 2020-11-18 2021-10-12 Anebulo Pharmaceuticals, Inc. Formulations and methods for treating acute cannabinoid overdose
CA3234167A1 (en) 2021-10-11 2023-04-20 Joseph Fenton Lawler Crystalline forms of a cannabinoid receptor type 1 (cb1) modulator and methods of use and preparation thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB872447A (en) * 1958-12-23 1961-07-12 Lepetit Spa 1-carbamyl-3-substituted azetidines
US4226861A (en) 1978-04-18 1980-10-07 A. H. Robins Company, Inc. N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
IL68699A (en) * 1982-08-19 1986-08-31 Robins Co Inc A H 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them
US4505907A (en) 1982-09-02 1985-03-19 A. H. Robins Company, Inc. N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
IE58943B1 (en) * 1985-02-28 1993-12-01 Robins Co Inc A H 3-Aryloxy-azetidine-carboxamides
US4956359A (en) * 1985-02-28 1990-09-11 A. H. Robins Company, Inc. 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics

Also Published As

Publication number Publication date
EP1049672A1 (de) 2000-11-08
EP1049672B1 (de) 2003-09-17
JP4542263B2 (ja) 2010-09-08
ES2207171T3 (es) 2004-05-16
DE69911373T2 (de) 2004-07-01
US6403574B1 (en) 2002-06-11
PT1049672E (pt) 2004-02-27
DE69911373D1 (de) 2003-10-23
AU2287499A (en) 1999-08-09
DK1049672T3 (da) 2004-01-19
WO1999037612A1 (en) 1999-07-29
JP2002501045A (ja) 2002-01-15

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