DK0876343T3 - Aromatiske ketosyrer og derivater deraf som inhibitorer af matrixmetalloproteinaser - Google Patents
Aromatiske ketosyrer og derivater deraf som inhibitorer af matrixmetalloproteinaserInfo
- Publication number
- DK0876343T3 DK0876343T3 DK96940614T DK96940614T DK0876343T3 DK 0876343 T3 DK0876343 T3 DK 0876343T3 DK 96940614 T DK96940614 T DK 96940614T DK 96940614 T DK96940614 T DK 96940614T DK 0876343 T3 DK0876343 T3 DK 0876343T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- inhibitors
- derivatives
- matrix metalloproteinases
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US948995P | 1995-12-22 | 1995-12-22 | |
PCT/US1996/018925 WO1997023459A1 (en) | 1995-12-22 | 1996-11-27 | Aromatic keto-acids and their derivatives as inhibitors of matrix metalloproteinases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0876343T3 true DK0876343T3 (da) | 2002-07-01 |
Family
ID=21737977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96940614T DK0876343T3 (da) | 1995-12-22 | 1996-11-27 | Aromatiske ketosyrer og derivater deraf som inhibitorer af matrixmetalloproteinaser |
Country Status (19)
Country | Link |
---|---|
US (1) | US6008220A (da) |
EP (1) | EP0876343B1 (da) |
JP (1) | JP2000502343A (da) |
AT (1) | ATE214368T1 (da) |
AU (1) | AU713174C (da) |
BG (1) | BG63461B1 (da) |
BR (1) | BR9612188A (da) |
CZ (1) | CZ287868B6 (da) |
DE (1) | DE69619865T2 (da) |
DK (1) | DK0876343T3 (da) |
ES (1) | ES2175155T3 (da) |
HU (1) | HU222986B1 (da) |
NO (1) | NO309470B1 (da) |
NZ (1) | NZ323329A (da) |
PL (1) | PL327494A1 (da) |
PT (1) | PT876343E (da) |
SK (1) | SK87598A3 (da) |
WO (1) | WO1997023459A1 (da) |
ZA (1) | ZA9610722B (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6153757A (en) * | 1995-12-08 | 2000-11-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors and intermediates useful for their preparation |
US6500948B1 (en) | 1995-12-08 | 2002-12-31 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors-compositions, uses preparation and intermediates thereof |
US5795985A (en) * | 1996-03-05 | 1998-08-18 | Ciba Specialty Chemicals Corporation | Phenyl alkyl ketone substituted by cyclic amine and a process for the preparation thereof |
US6174915B1 (en) | 1997-03-25 | 2001-01-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
US6008243A (en) * | 1996-10-24 | 1999-12-28 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
EP1366765A1 (en) * | 1996-12-17 | 2003-12-03 | Warner-Lambert Company Llc | Use of matrix metalloproteinase inhibitors for treating neurological disorders and promoting wound healing |
PT946166E (pt) | 1996-12-17 | 2004-06-30 | Warner Lambert Co | Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas |
US5985900A (en) * | 1997-04-01 | 1999-11-16 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
US6420427B1 (en) | 1997-10-09 | 2002-07-16 | Ono Pharmaceutical Co., Ltd. | Aminobutyric acid derivatives |
US6288063B1 (en) | 1998-05-27 | 2001-09-11 | Bayer Corporation | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors |
US20040225077A1 (en) | 2002-12-30 | 2004-11-11 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
MY150088A (en) * | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
WO2010011302A1 (en) * | 2008-07-22 | 2010-01-28 | Chdi, Inc. | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
CN106518845B (zh) | 2011-08-30 | 2019-09-13 | Chdi基金会股份有限公司 | 犬尿氨酸-3-单加氧酶抑制剂、药物组合物及其使用方法 |
BR112014004845A2 (pt) | 2011-08-30 | 2017-04-04 | Chdi Foundation Inc | pelo menos uma entidade química; pelo menos um composto; composição farmacêutica; uso de uma quantidade terapeuticamente eficaz de pelo menos uma entidade química; composição farmacêutica embalada |
SG11201700341PA (en) | 2014-07-17 | 2017-02-27 | Chdi Foundation Inc | Methods and compositions for treating hiv-related disorders |
US20170327457A1 (en) * | 2014-09-09 | 2017-11-16 | Bristol-Myers Squibb Company | Phenyl-(aza)cycloalkyl carboxylic acid gpr120 modulators |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0821671T3 (da) * | 1995-04-20 | 2001-04-23 | Pfizer | Arylsulfonylhydroxamsyrederivater som MMP- og TNF-inhibitorer |
AU741768B2 (en) * | 1996-12-09 | 2001-12-06 | Warner-Lambert Company | Method for treating and preventing heart failure and ventricular dilatation |
PT946166E (pt) * | 1996-12-17 | 2004-06-30 | Warner Lambert Co | Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas |
-
1996
- 1996-11-27 NZ NZ323329A patent/NZ323329A/en unknown
- 1996-11-27 DK DK96940614T patent/DK0876343T3/da active
- 1996-11-27 CZ CZ19981952A patent/CZ287868B6/cs not_active IP Right Cessation
- 1996-11-27 SK SK875-98A patent/SK87598A3/sk unknown
- 1996-11-27 PL PL96327494A patent/PL327494A1/xx unknown
- 1996-11-27 WO PCT/US1996/018925 patent/WO1997023459A1/en active IP Right Grant
- 1996-11-27 DE DE69619865T patent/DE69619865T2/de not_active Expired - Fee Related
- 1996-11-27 AU AU10249/97A patent/AU713174C/en not_active Ceased
- 1996-11-27 HU HU9902079A patent/HU222986B1/hu not_active IP Right Cessation
- 1996-11-27 AT AT96940614T patent/ATE214368T1/de not_active IP Right Cessation
- 1996-11-27 US US09/077,715 patent/US6008220A/en not_active Expired - Fee Related
- 1996-11-27 EP EP96940614A patent/EP0876343B1/en not_active Expired - Lifetime
- 1996-11-27 PT PT96940614T patent/PT876343E/pt unknown
- 1996-11-27 JP JP9523645A patent/JP2000502343A/ja not_active Abandoned
- 1996-11-27 BR BR9612188A patent/BR9612188A/pt not_active Application Discontinuation
- 1996-11-27 ES ES96940614T patent/ES2175155T3/es not_active Expired - Lifetime
- 1996-12-19 ZA ZA9610722A patent/ZA9610722B/xx unknown
-
1998
- 1998-05-20 BG BG102471A patent/BG63461B1/bg unknown
- 1998-06-19 NO NO982840A patent/NO309470B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
DE69619865T2 (de) | 2002-11-07 |
EP0876343A1 (en) | 1998-11-11 |
CZ287868B6 (en) | 2001-02-14 |
NO982840L (no) | 1998-06-19 |
US6008220A (en) | 1999-12-28 |
ATE214368T1 (de) | 2002-03-15 |
SK87598A3 (en) | 1999-04-13 |
BG102471A (en) | 1999-08-31 |
NO982840D0 (no) | 1998-06-19 |
WO1997023459A1 (en) | 1997-07-03 |
HUP9902079A3 (en) | 2000-06-28 |
NO309470B1 (no) | 2001-02-05 |
PL327494A1 (en) | 1998-12-21 |
ES2175155T3 (es) | 2002-11-16 |
NZ323329A (en) | 1999-02-25 |
AU713174C (en) | 2002-05-02 |
ZA9610722B (en) | 1997-06-27 |
DE69619865D1 (de) | 2002-04-18 |
HU222986B1 (hu) | 2004-01-28 |
JP2000502343A (ja) | 2000-02-29 |
AU713174B2 (en) | 1999-11-25 |
AU1024997A (en) | 1997-07-17 |
MX9803315A (es) | 1998-09-30 |
BR9612188A (pt) | 1999-07-13 |
BG63461B1 (bg) | 2002-02-28 |
PT876343E (pt) | 2002-08-30 |
HUP9902079A2 (hu) | 1999-10-28 |
EP0876343B1 (en) | 2002-03-13 |
CZ195298A3 (cs) | 1998-09-16 |
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