DK0840620T3 - IL-8-antagonister til behandling af astma - Google Patents

IL-8-antagonister til behandling af astma

Info

Publication number: DK0840620T3
Authority: DK; Denmark
Prior art keywords: asthma; treatment; antagonists; methods; monoclonal antibodies
Prior art date: 1995-06-27

Application number

DK96921804T

Other languages

Danish (da)

English (en)

Inventor

Caroline A Hebert

Rhona C Kabakoff

Mark W Moore

Original Assignee

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-27

Filing date

1996-06-26

Publication date

2002-02-04

1996-06-26 Application filed by Genentech Inc filed Critical Genentech Inc

2002-02-04 Application granted granted Critical

2002-02-04 Publication of DK0840620T3 publication Critical patent/DK0840620T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)

DK96921804T 1995-06-27 1996-06-26 IL-8-antagonister til behandling af astma DK0840620T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/491,334 US5874080A (en)	1994-03-03	1995-06-27	Anti-IL-8 monoclonal antibodies for treatment of asthma
PCT/US1996/011033 WO1997001354A1 (fr)	1995-06-27	1996-06-26	Antagonistes d'il-8 utilises pour le traitement des troubles inflammatoires et de l'asthme

Publications (1)

Publication Number	Publication Date
DK0840620T3 true DK0840620T3 (da)	2002-02-04

Family

ID=23951745

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96921804T DK0840620T3 (da)	1995-06-27	1996-06-26	IL-8-antagonister til behandling af astma

Country Status (12)

Country	Link
US (1)	US5874080A (fr)
EP (1)	EP0840620B1 (fr)
JP (1)	JPH11509840A (fr)
AT (1)	ATE206621T1 (fr)
AU (1)	AU727343C (fr)
CA (1)	CA2222024A1 (fr)
DE (1)	DE69615843T2 (fr)
DK (1)	DK0840620T3 (fr)
ES (1)	ES2165506T3 (fr)
NZ (1)	NZ311561A (fr)
PT (1)	PT840620E (fr)
WO (1)	WO1997001354A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100261941B1 (ko) *	1994-07-13	2000-07-15	나가야마 오사무	사람의 인터루킨-8에 대한 재구성 사람항체
US7122636B1 (en)	1997-02-21	2006-10-17	Genentech, Inc.	Antibody fragment-polymer conjugates and uses of same
US6870033B1 (en) *	1997-02-21	2005-03-22	Genentech, Inc.	Antibody fragment-polymer conjugates and humanized anti-IL-8 monoclonal antibodies
US6468532B1 (en)	1998-01-22	2002-10-22	Genentech, Inc.	Methods of treating inflammatory diseases with anti-IL-8 antibody fragment-polymer conjugates
US6458355B1 (en)	1998-01-22	2002-10-01	Genentech, Inc.	Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates
JP2002518300A (ja) *	1998-06-17	2002-06-25	スミスクライン・ビーチャム・コーポレイション	Ｉｌ−８受容体アンタゴニスト
US20080038274A1 (en) *	1999-09-23	2008-02-14	Foster Keith A	Inhibition of secretion from non-neuronal cells
US6753135B2 (en) *	2000-09-20	2004-06-22	Surromed, Inc.	Biological markers for evaluating therapeutic treatment of inflammatory and autoimmune disorders
EP1494711A4 (fr) *	2002-03-19	2008-05-28	Abgenix Inc	Procedes de traitement de la broncho-pneumopathie chronique obstructive (bpco)
CN1980948B (zh) *	2002-11-27	2011-08-10	Dmi生物科学公司	治疗由增强磷酸化介导的疾病和病况
WO2004058797A2 (fr)	2002-12-16	2004-07-15	Medarex, Inc.	Anticorps monoclonaux humains diriges contre l'interleukine 8 (il-8)
AU2006236417B2 (en) *	2005-04-20	2011-02-03	Amgen Fremont Inc.	High affinity fully human monoclonal antibodies to interleukin-8 and epitopes for such antibodies
KR20200108868A (ko)	2018-01-12	2020-09-21	브리스톨-마이어스 스큅 컴퍼니	암을 치료하기 위한 항-il-8 항체 및 항-pd-1 항체와의 조합 요법
WO2023192478A1 (fr)	2022-04-01	2023-10-05	Bristol-Myers Squibb Company	Polythérapie avec des anticorps anti-il-8 et des anticorps anti-pd-1 pour le traitement du cancer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4816567A (en) *	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
US5229275A (en) *	1990-04-26	1993-07-20	Akzo N.V.	In-vitro method for producing antigen-specific human monoclonal antibodies
PT98072B (pt) *	1990-06-22	1998-11-30	Chiron Corp	Processo para a preparacao de polipeptidos contendo proteina macrofagica inflamatoria humana mip-2 alfa por metodos recombinantes e de composicoes farmaceuticas que os contem
US5234911A (en) *	1990-07-09	1993-08-10	Gist-Brocades, N.V.	Substance with interleukin-8 inhibiting activity and process for its preparation
IE913192A1 (en) *	1990-09-12	1992-02-25	Scripps Research Inst	Active site of interleukin-8: polypeptide analogs and¹antibodies
JPH06503952A (ja) *	1990-09-28	1994-05-12	カイロン　コーポレイション	Ｇｒｏ遺伝子、蛋白質、及びその使用
WO1992006697A1 (fr) *	1990-10-23	1992-04-30	Repligen Corporation	Composition anti-inflammatoire
AU8910891A (en) *	1990-11-20	1992-06-11	National Heart & Lung Institute, The	Treatment of lung diseases
JPH0597A (ja) *	1991-06-21	1993-01-08	Snow Brand Milk Prod Co Ltd	新規抗ｔｃｆ−ｉｉモノクローナル抗体及びそれを用いるｔｃｆ−ｉｉの測定方法
WO1993001826A1 (fr) *	1991-07-19	1993-02-04	East Carolina University	Methode de traitement de l'asthme
AU5087393A (en) *	1992-08-21	1994-03-15	Scripps Research Institute, The	Therapeutic compositions and methods for inhibiting il-8-mediated inflammation
WO1995023865A1 (fr) *	1994-03-03	1995-09-08	Genentech, Inc.	Anticorps monoclonaux anti-il-8 pour le traitement des troubles

1995
- 1995-06-27 US US08/491,334 patent/US5874080A/en not_active Expired - Fee Related
1996
- 1996-06-26 AU AU62924/96A patent/AU727343C/en not_active Ceased
- 1996-06-26 PT PT96921804T patent/PT840620E/pt unknown
- 1996-06-26 DE DE69615843T patent/DE69615843T2/de not_active Expired - Fee Related
- 1996-06-26 EP EP96921804A patent/EP0840620B1/fr not_active Expired - Lifetime
- 1996-06-26 JP JP9504031A patent/JPH11509840A/ja not_active Ceased
- 1996-06-26 WO PCT/US1996/011033 patent/WO1997001354A1/fr active IP Right Grant
- 1996-06-26 DK DK96921804T patent/DK0840620T3/da active
- 1996-06-26 CA CA002222024A patent/CA2222024A1/fr not_active Abandoned
- 1996-06-26 NZ NZ311561A patent/NZ311561A/en unknown
- 1996-06-26 AT AT96921804T patent/ATE206621T1/de not_active IP Right Cessation
- 1996-06-26 ES ES96921804T patent/ES2165506T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH11509840A (ja)	1999-08-31
DE69615843D1 (de)	2001-11-15
EP0840620A1 (fr)	1998-05-13
WO1997001354A1 (fr)	1997-01-16
AU727343C (en)	2002-01-03
CA2222024A1 (fr)	1997-01-16
US5874080A (en)	1999-02-23
ES2165506T3 (es)	2002-03-16
EP0840620B1 (fr)	2001-10-10
AU6292496A (en)	1997-01-30
ATE206621T1 (de)	2001-10-15
NZ311561A (en)	1999-10-28
AU727343B2 (en)	2000-12-14
DE69615843T2 (de)	2002-05-16
PT840620E (pt)	2002-04-29

Publication	Publication Date	Title
DK0840620T3 (da)	2002-02-04	IL-8-antagonister til behandling af astma
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DK0432249T3 (da)	1997-02-17	Monoklonale antistoffer over for beta-kæden i leukocytadhæsionsreceptoren, fremgangsmåder til fremstilling af disse antistoffer og anvendelse heraf
DE69434097D1 (de)	2004-12-02	Apoptose induzierender monoklonaler antikörper
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ITRM920457A0 (it)	1992-06-17	Anticorpi monoclonali che riconoscono un epitopo della p-glicoproteinaumana.
DE3581288D1 (de)	1991-02-14	Antileishmania monoklonale antikoerper, diese antikoerper ausscheidende hybridomas, von diesen antikoerpern erkannte leishmaniaantigene, verfahren zur herstellung und verwendung von diesen monoklonalen antikoerpern und antigenen.
DE69738312D1 (de)	2008-01-03	Hepatitis b monoklonale antikörper
DK0709455T3 (da)	1999-02-22	Monoklonalt antistof med humanglicentin, hybridoma til fremstilling af antistoffet og assaymetode for humanglicentin ved an
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DK26587A (da)	1987-07-21	Monoklonalt antistof, maalemetode for glucosyleret protein ved anvendelse af det monoklonale antistofog kit omfattende dette
TR199501542A2 (tr)	1996-07-21	Bagisiklik önleyici aktiviteye sahip monoklonal antikor parcalari.
DK557289D0 (da)	1989-11-08	Monoklonalt, fucosylceramiderkendende antistof, dets fremstilling og anvendelse samt hybridoma til fremstillingen
DE3485712D1 (de)	1992-06-17	Monoklonale antikoerper gegen menschliche nierenkrebsantigene und verfahren.
DE59608073D1 (de)	2001-12-06	Antikörper gegen ein, einen histidin-anteil aufweisendes fusionspolypeptid
NO20004251D0 (no)	2000-08-24	Humaniserte anti-CEA monoklonale antistoffer med høy affinitet
DE3785795D1 (de)	1993-06-17	Monoklonale anti-menschliche magenkrebs-antikoerper.
ITRM920223A0 (it)	1992-03-27	Anticorpi monoclonali anti-idiopici diretti contro anticorpi anti-tnf.
DE3683178D1 (de)	1992-02-13	Methode zur herstellung monoklonaler antikoerper gegen plasminogenaktivatorfaktor.
DE69020315D1 (de)	1995-07-27	Monoklonaler antikörper gegen c-reaktives protein.
NO894555D0 (no)	1989-11-15	Monoklonalt antistoff som spesifikt gjenkjenner n-glycolyl type gm2, hybridom som produserer antistoff og fremgangsmaate for fremstilling av hybridomet.