DK0830600T3 - Funktionelt bioassay for G-proteinkoblede receptoragonister og -antagonister - Google Patents
Funktionelt bioassay for G-proteinkoblede receptoragonister og -antagonisterInfo
- Publication number
- DK0830600T3 DK0830600T3 DK96918089T DK96918089T DK0830600T3 DK 0830600 T3 DK0830600 T3 DK 0830600T3 DK 96918089 T DK96918089 T DK 96918089T DK 96918089 T DK96918089 T DK 96918089T DK 0830600 T3 DK0830600 T3 DK 0830600T3
- Authority
- DK
- Denmark
- Prior art keywords
- gpcrs
- antagonists
- identify
- indicator cells
- protein
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47980395A | 1995-06-07 | 1995-06-07 | |
PCT/US1996/008895 WO1996041169A1 (fr) | 1995-06-07 | 1996-06-05 | Dosage biologique fonctionnel pour les agonistes et antagonistes des recepteurs couples de proteine g |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0830600T3 true DK0830600T3 (da) | 2003-12-22 |
Family
ID=23905512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96918089T DK0830600T3 (da) | 1995-06-07 | 1996-06-05 | Funktionelt bioassay for G-proteinkoblede receptoragonister og -antagonister |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0830600B1 (fr) |
JP (1) | JPH11507518A (fr) |
AT (1) | ATE248373T1 (fr) |
AU (1) | AU730875C (fr) |
CA (1) | CA2220715C (fr) |
DE (1) | DE69629684T2 (fr) |
DK (1) | DK0830600T3 (fr) |
WO (1) | WO1996041169A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2186979A1 (fr) * | 1996-10-02 | 1998-04-02 | Michael Dennis | Methodes pour analyser des antagonistes quant a leur capacite de modification de l'activite des recepteurs associes a la proteine g |
CA2192754A1 (fr) | 1996-12-12 | 1998-06-12 | Jacques Drouin | Nur-re, element qui lie les dimeres de recepteurs nucleaires nur; methode d'obtention et utilisation |
US6403305B1 (en) * | 1997-02-06 | 2002-06-11 | Cornell Research Foundation, Inc. | Methods of identifying peptide agonists or negative antagonists of a G protein coupled receptor |
EP0878542A3 (fr) * | 1997-04-22 | 2000-04-19 | Smithkline Beecham Corporation | Clone HMTMF81 de cADN codant pour un nouveau récepteur 7-transmembranaire humain |
EP0874047A3 (fr) * | 1997-04-22 | 2000-04-19 | Smithkline Beecham Corporation | Clone HMTMF81 de cADN codant pour un nouveau récepteur 7-transmembranaire humain |
US20020146740A1 (en) * | 1997-10-09 | 2002-10-10 | William D. Huse | Method for identifying optimal binding ligands to a receptor |
MXPA01001176A (es) * | 1998-07-31 | 2005-07-25 | Arena Pharm Inc | Receptores huerfanos acoplados a la proteina g constitutivamente activados endogenos. |
EP1242824A2 (fr) * | 1999-12-30 | 2002-09-25 | 7TM Pharma | Detection au moyen de molecules cibles biologiques possedant des sites de liaison d'ions metalliques |
JP4908721B2 (ja) * | 2000-07-17 | 2012-04-04 | 中外製薬株式会社 | 生理活性を有するリガンドのスクリーニング方法 |
US6902902B2 (en) * | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
EP2490021A1 (fr) * | 2011-02-18 | 2012-08-22 | Biotempt B.V. | Modulateurs de signalisation PRR et GPCR |
KR101452864B1 (ko) | 2011-11-17 | 2014-11-04 | 서울대학교산학협력단 | Gpcr19 경로의 활성화에 의한 골수 유래 면역 조절 세포 및 면역 조절 b 림프구의 체내외 증폭 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993003137A1 (fr) * | 1991-08-07 | 1993-02-18 | Washington University | Recepteur de substance p humaine |
CA2138999C (fr) * | 1992-06-23 | 2010-02-23 | Stuart C. Sealfon | Clonage et expression d'un recepteur de la gnrh |
AU5361294A (en) * | 1992-10-15 | 1994-05-09 | Merck & Co., Inc. | Cho cells expressing human endothelin receptors |
GB2283239A (en) * | 1993-10-29 | 1995-05-03 | Ucb Sa | Human H1 histamine receptor |
US5677184A (en) * | 1994-04-19 | 1997-10-14 | Takeda Chemical Industries, Ltd. | CHO cells that express human LH-RH receptor |
-
1996
- 1996-06-05 DE DE69629684T patent/DE69629684T2/de not_active Expired - Fee Related
- 1996-06-05 EP EP96918089A patent/EP0830600B1/fr not_active Revoked
- 1996-06-05 AT AT96918089T patent/ATE248373T1/de not_active IP Right Cessation
- 1996-06-05 WO PCT/US1996/008895 patent/WO1996041169A1/fr not_active Application Discontinuation
- 1996-06-05 AU AU60437/96A patent/AU730875C/en not_active Ceased
- 1996-06-05 JP JP9501357A patent/JPH11507518A/ja not_active Ceased
- 1996-06-05 CA CA002220715A patent/CA2220715C/fr not_active Expired - Fee Related
- 1996-06-05 DK DK96918089T patent/DK0830600T3/da active
Also Published As
Publication number | Publication date |
---|---|
AU6043796A (en) | 1996-12-30 |
AU730875C (en) | 2003-01-16 |
EP0830600A4 (fr) | 2000-04-05 |
JPH11507518A (ja) | 1999-07-06 |
ATE248373T1 (de) | 2003-09-15 |
AU730875B2 (en) | 2001-03-15 |
DE69629684D1 (de) | 2003-10-02 |
DE69629684T2 (de) | 2004-02-26 |
EP0830600A1 (fr) | 1998-03-25 |
WO1996041169A1 (fr) | 1996-12-19 |
CA2220715A1 (fr) | 1996-12-19 |
CA2220715C (fr) | 2004-11-02 |
EP0830600B1 (fr) | 2003-08-27 |
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