DK0701554T3 - Benzisoselen-azolinderivater og -azinderivater, fremgangsmåde til fremstilling heraf og deres terapeutiske anvendelse - Google Patents

Benzisoselen-azolinderivater og -azinderivater, fremgangsmåde til fremstilling heraf og deres terapeutiske anvendelse

Info

Publication number
DK0701554T3
DK0701554T3 DK95916723T DK95916723T DK0701554T3 DK 0701554 T3 DK0701554 T3 DK 0701554T3 DK 95916723 T DK95916723 T DK 95916723T DK 95916723 T DK95916723 T DK 95916723T DK 0701554 T3 DK0701554 T3 DK 0701554T3
Authority
DK
Denmark
Prior art keywords
derivatives
benzisoselenazoline
preparation
therapeutic use
azoline
Prior art date
Application number
DK95916723T
Other languages
English (en)
Inventor
Jean Chaudiere
Marc Moutet
Jean-Claude Yadan
Irene Erdelmeier
Original Assignee
Oxis Isle Of Man Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxis Isle Of Man Ltd filed Critical Oxis Isle Of Man Ltd
Application granted granted Critical
Publication of DK0701554T3 publication Critical patent/DK0701554T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D293/00—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • C07D293/10—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D293/00—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms
    • C07D293/10—Heterocyclic compounds containing rings having nitrogen and selenium or nitrogen and tellurium, with or without oxygen or sulfur atoms, as the ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D293/12—Selenazoles; Hydrogenated selenazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95916723T 1994-04-07 1995-04-07 Benzisoselen-azolinderivater og -azinderivater, fremgangsmåde til fremstilling heraf og deres terapeutiske anvendelse DK0701554T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404107A FR2718441B1 (fr) 1994-04-07 1994-04-07 Nouveaux composés de structure benzisoséléna-zoline et -zine, leur procédé de préparation et leurs applications thérapeutiques.
PCT/FR1995/000447 WO1995027706A1 (fr) 1994-04-07 1995-04-07 Nouveaux composes de structure benzisoselen-azolin et -azine, leur procede de preparation et leurs applications therapeutiques

Publications (1)

Publication Number Publication Date
DK0701554T3 true DK0701554T3 (da) 2001-10-08

Family

ID=9461850

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95916723T DK0701554T3 (da) 1994-04-07 1995-04-07 Benzisoselen-azolinderivater og -azinderivater, fremgangsmåde til fremstilling heraf og deres terapeutiske anvendelse

Country Status (10)

Country Link
US (2) US5968920A (da)
EP (1) EP0701554B1 (da)
JP (1) JP4044133B2 (da)
AU (1) AU692542B2 (da)
CA (1) CA2164642C (da)
DE (2) DE69521465T2 (da)
DK (1) DK0701554T3 (da)
ES (1) ES2161879T3 (da)
FR (1) FR2718441B1 (da)
WO (1) WO1995027706A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407083B1 (en) 1996-07-17 2002-06-18 Oxis International, Inc. Uses of novel organoselenium compounds with pro-oxidant activity
FR2751328B1 (fr) * 1996-07-17 1998-10-09 Oxis International Sa Utilisation de nouveaux composes organoselenies comme agents pro-oxydants ainsi que leurs procedes de preparation et des compositions pharmaceutiques en comportant application
AU727067B2 (en) * 1996-07-17 2000-11-30 Oxis Isle Of Man, Limited Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application thereof
FR2757860B1 (fr) 1996-12-27 1999-04-23 Oxis International Sa Composes organoselenies cycliques, leur preparation et leurs utilisations, notamment therapeutiques
FR2757857B1 (fr) * 1996-12-27 1999-04-23 Oxis International Sa Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques
BR0209965A (pt) 2001-05-21 2004-04-06 Alcon Inc Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
WO2008100628A2 (en) * 2007-02-16 2008-08-21 Synvista Therapeutics, Inc. Glutathione peroxidase mimetics for treatment of neurodegenerative, pulmonary and inflammatory diseases
WO2008100629A2 (en) * 2007-02-16 2008-08-21 Synvista Therapeutics, Inc. Glutathione peroxidase mimetics for the treatment of dermatoses
EP2220208A4 (en) * 2007-11-23 2010-12-29 Rappaport Family Inst For Res USE OF HAPTOGLOBIN GENOTYPING IN THE DIAGNOSIS AND TREATMENT OF CARDIOVASCULAR DISEASE
EP2878197B1 (en) * 2012-07-25 2018-12-26 Osaka University Tissue preservation solution and tissue preservation method
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
CN111423395A (zh) 2015-12-14 2020-07-17 杭州健昵福生物科技有限公司 一种具有药物活性的1，3，4-硒二唑类化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027074A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolon enthaltende pharmazeutische praeparate und ihre verwendung
DE3407511A1 (de) * 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolthione, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3444135A1 (de) * 1984-12-04 1986-06-05 A. Nattermann & Cie GmbH, 5000 Köln Selenoxide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
FR2669633B1 (fr) * 1990-11-23 1993-01-22 Adir Nouveaux derives de la benzoselenazolinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
JP4044133B2 (ja) 2008-02-06
EP0701554B1 (fr) 2001-06-27
US6093532A (en) 2000-07-25
US5968920A (en) 1999-10-19
WO1995027706A1 (fr) 1995-10-19
CA2164642C (en) 2008-03-25
DE69521465D1 (de) 2001-08-02
AU2311195A (en) 1995-10-30
CA2164642A1 (en) 1995-10-19
JPH11501005A (ja) 1999-01-26
DE69521465T2 (de) 2002-05-29
DE701554T1 (de) 1996-10-10
FR2718441A1 (fr) 1995-10-13
EP0701554A1 (fr) 1996-03-20
FR2718441B1 (fr) 1996-06-28
ES2161879T3 (es) 2001-12-16
AU692542B2 (en) 1998-06-11

Similar Documents

Publication Publication Date Title
DK0740668T3 (da) Tetracykliske derivater, fremgangsmåde til deres fremstilling og deres anvendelse
NO954369L (no) Oksazolidindionderivater, deres fremstilling og anvendelse
DK0869126T3 (da) Dithiolanderivater, deres fremstilling og deres terapeutiske virkning
NO951095L (no) Tiazolidin- og oksazolidinderivater, deres fremstilling og medisinske bruk
NO924650D0 (no) Dialkoksy-pyridinyl-benzimidazolderivater, fremgangsmaate for deres fremstilling og deres farmasoeytiske anvendelse
NO986024L (no) Substituerte 3,5-difenyl-1,2,4-triazoler og deres anvendelse som farmas°ytiske metallchelatorer
DK0811006T3 (da) Benzopyranholdige forbindelser og fremgangsmåde til deres anvendelse
NO980720D0 (no) Pyridazin-3-on-derivater, deres anvendelse og mellomprodukter for deres fremstilling
NO943682D0 (no) Imidazol-4-yl-piperidin-derivater, deres fremstilling og terapeutiske anvendelse
NO922275D0 (no) Aryletere, deres fremstilling og fremgangsmaate for behandling
DK0871656T3 (da) Dolastatinderivater, deres fremstilling og anvendelse
NO932120D0 (no) Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
NO955326D0 (no) Isokinolinderivater, fremgangsmåte for deres fremstilling og terapeutiske anvendelse
NO943794L (no) 4-difenylmethylpiperidinderivater, og fremgangsmåte for deres fremstilling
DK0701554T3 (da) Benzisoselen-azolinderivater og -azinderivater, fremgangsmåde til fremstilling heraf og deres terapeutiske anvendelse
NO985307L (no) Distamycinderivater, fremgangsmÕte for deres fremstilling, og deres anvende
NO962477D0 (no) Benzamidderivater, deres fremstilling og deres terapautiske anvendelse
NO20001934D0 (no) 3-Substituerte tetrahydropyridopyrimidinon-derivater, deres fremstilling og anvendelse
NO940130D0 (no) Benzimidazolderivater, fremgangsmaate for deres fremstilling og te rapeutisk anvendelse derav
DK530689D0 (da) Adenylcyclasederivater, fremgangsmaade til fremstilling deraf og deres anvendelse
DK0835254T3 (da) Oxazolidinonderivater, deres fremstilling og deres terapeutiske anvendelse
NO955242D0 (no) Piperidinderivater, fremgangsmåte for fremstilling derav og deres terapeutiske anvendelse
NO984624D0 (no) Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav
NO951811D0 (no) Kinolin- og benzimidazolderivater, deres fremstilling og anvendelse
NO980929D0 (no) Nye benzoksazindionderivater, fremgangsmåte for deres fremstilling og deres anvendelse