DK0691967T3 - Nitrogenholdige kondenserede heterocykliske forbindelser - Google Patents
Nitrogenholdige kondenserede heterocykliske forbindelserInfo
- Publication number
- DK0691967T3 DK0691967T3 DK94910047T DK94910047T DK0691967T3 DK 0691967 T3 DK0691967 T3 DK 0691967T3 DK 94910047 T DK94910047 T DK 94910047T DK 94910047 T DK94910047 T DK 94910047T DK 0691967 T3 DK0691967 T3 DK 0691967T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- formula
- nitrogen
- image
- group represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9513193 | 1993-03-31 | ||
PCT/JP1994/000446 WO1994022855A1 (en) | 1993-03-31 | 1994-03-18 | Nitrogen-containing fused-heterocycle compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0691967T3 true DK0691967T3 (da) | 1999-06-07 |
Family
ID=14129274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94910047T DK0691967T3 (da) | 1993-03-31 | 1994-03-18 | Nitrogenholdige kondenserede heterocykliske forbindelser |
Country Status (10)
Country | Link |
---|---|
US (1) | US5707998A (da) |
EP (1) | EP0691967B1 (da) |
AT (1) | ATE170519T1 (da) |
AU (1) | AU6264194A (da) |
DE (1) | DE69413019T2 (da) |
DK (1) | DK0691967T3 (da) |
ES (1) | ES2124397T3 (da) |
HU (1) | HUT73783A (da) |
PH (1) | PH31122A (da) |
WO (1) | WO1994022855A1 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5869486A (en) * | 1995-02-24 | 1999-02-09 | Ono Pharmaceutical Co., Ltd. | Fused pyrimidines and pyriazines as pharmaceutical compounds |
TW381092B (en) * | 1995-07-07 | 2000-02-01 | Otsuka Pharma Co Ltd | Novel benzimidazole derivatives for use in treating arteriosclerotic diseases |
US6022893A (en) * | 1995-08-08 | 2000-02-08 | Ono Pharmaceutical Co., Ltd. | Hydroxamic acid derivatives |
DE19644228A1 (de) * | 1996-10-24 | 1998-04-30 | Merck Patent Gmbh | Thienopyrimidine |
US6339099B1 (en) * | 1997-06-20 | 2002-01-15 | Dupont Pharmaceuticals Company | Guanidine mimics as factor Xa inhibitors |
ZA9810766B (en) * | 1997-11-28 | 1999-05-25 | Mochida Pharm Co Ltd | Novel compounds having cgmp-pde inhibitory activity |
DE19819023A1 (de) | 1998-04-29 | 1999-11-04 | Merck Patent Gmbh | Thienopyrimidine |
DE10001021A1 (de) * | 2000-01-13 | 2001-07-19 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
PE20020394A1 (es) | 2000-08-18 | 2002-06-21 | Agouron Pharma | Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2 |
US6576644B2 (en) * | 2000-09-06 | 2003-06-10 | Bristol-Myers Squibb Co. | Quinoline inhibitors of cGMP phosphodiesterase |
CA2565812C (en) * | 2004-05-06 | 2012-03-13 | Warner-Lambert Company Llc | 4-phenylamino-quinazolin-6-yl-amides |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
WO2008009077A2 (en) * | 2006-07-20 | 2008-01-24 | Gilead Sciences, Inc. | 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives and pharmaceutical compositions useful for treating viral infections |
US9259426B2 (en) * | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
AR076024A1 (es) | 2009-04-03 | 2011-05-11 | Schering Corp | Derivados de heterociclos biciclicos puenteados y metodos de uso de los mismos |
CN107074772A (zh) * | 2014-08-14 | 2017-08-18 | 拜耳医药股份有限公司 | 取代的喹啉‑4‑甲酰胺及其用途 |
EP3722297A1 (en) | 2015-03-04 | 2020-10-14 | Gilead Sciences, Inc. | Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds |
AU2017318601B2 (en) | 2016-09-02 | 2020-09-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
WO2018045150A1 (en) | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators |
TWI751517B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TW202210480A (zh) | 2019-04-17 | 2022-03-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
JP2022534751A (ja) * | 2019-05-31 | 2022-08-03 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | P2x3阻害剤としてのアミノキナゾリン誘導体 |
TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0647540B2 (ja) * | 1985-07-16 | 1994-06-22 | エーザイ株式会社 | 虚血性心疾患・不整脈治療・予防剤 |
US5260461A (en) * | 1988-01-11 | 1993-11-09 | Massachusetts Institute Of Technology | Ligands for ADH: cinchona alkaloids and moderately sized organic substituents linked through a planar aromatic spacer group |
FR2643903A1 (fr) * | 1989-03-03 | 1990-09-07 | Union Pharma Scient Appl | Nouveaux derives de benzimidazole, leurs procedes de preparation, intermediaires de synthese, compositions pharmaceutiques les contenant, utiles notamment pour le traitement des maladies cardiovasculaires, et des ulceres duodenaux |
US5034393A (en) * | 1989-07-27 | 1991-07-23 | Dowelanco | Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives |
AU656154B2 (en) * | 1990-11-06 | 1995-01-27 | Astellas Pharma Inc. | Fused pyrazine derivative |
EP0510235A1 (en) * | 1991-04-26 | 1992-10-28 | Dong-A Pharm. Co., Ltd. | Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same |
PT100905A (pt) * | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
GB9300059D0 (en) * | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
JP2657760B2 (ja) * | 1992-07-15 | 1997-09-24 | 小野薬品工業株式会社 | 4−アミノキナゾリン誘導体およびそれを含有する医薬品 |
GB9314893D0 (en) * | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Quinazoline derivatives |
-
1994
- 1994-03-16 PH PH47932A patent/PH31122A/en unknown
- 1994-03-18 HU HU9501939A patent/HUT73783A/hu unknown
- 1994-03-18 DK DK94910047T patent/DK0691967T3/da active
- 1994-03-18 EP EP94910047A patent/EP0691967B1/en not_active Expired - Lifetime
- 1994-03-18 DE DE69413019T patent/DE69413019T2/de not_active Expired - Lifetime
- 1994-03-18 AU AU62641/94A patent/AU6264194A/en not_active Abandoned
- 1994-03-18 ES ES94910047T patent/ES2124397T3/es not_active Expired - Lifetime
- 1994-03-18 WO PCT/JP1994/000446 patent/WO1994022855A1/en active IP Right Grant
- 1994-03-18 US US08/525,739 patent/US5707998A/en not_active Expired - Lifetime
- 1994-03-18 AT AT94910047T patent/ATE170519T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0691967B1 (en) | 1998-09-02 |
ES2124397T3 (es) | 1999-02-01 |
HUT73783A (en) | 1996-09-30 |
DE69413019T2 (de) | 1999-06-02 |
WO1994022855A1 (en) | 1994-10-13 |
AU6264194A (en) | 1994-10-24 |
DE69413019D1 (de) | 1998-10-08 |
EP0691967A1 (en) | 1996-01-17 |
HU9501939D0 (en) | 1995-09-28 |
PH31122A (en) | 1998-02-23 |
ATE170519T1 (de) | 1998-09-15 |
US5707998A (en) | 1998-01-13 |
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