DK0668279T3 - 6-azaindol thromboxansytaseinhibitor - Google Patents

6-azaindol thromboxansytaseinhibitor

Info

Publication number: DK0668279T3
Authority: DK; Denmark
Prior art keywords: azaindole; thromboxane synthase; synthase inhibitor; integer; zero
Prior art date: 1994-01-31

Application number

DK95300551T

Other languages

English (en)

Inventor

Joseph Anthony Jakubowski

Alan David Palkowitz

Sandra Kay Sigmund

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1995-01-30

Publication date

2001-08-27

1995-01-30 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2001-08-27 Application granted granted Critical

2001-08-27 Publication of DK0668279T3 publication Critical patent/DK0668279T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

DK95300551T 1994-01-31 1995-01-30 6-azaindol thromboxansytaseinhibitor DK0668279T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/189,212 US5468757A (en)	1994-01-31	1994-01-31	6-azaindole thromboxane synthase inhibitors

Publications (1)

Publication Number	Publication Date
DK0668279T3 true DK0668279T3 (da)	2001-08-27

Family

ID=22696403

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95300551T DK0668279T3 (da)	1994-01-31	1995-01-30	6-azaindol thromboxansytaseinhibitor

Country Status (11)

Country	Link
US (1)	US5468757A (da)
EP (1)	EP0668279B1 (da)
JP (1)	JPH0853448A (da)
AT (1)	ATE202103T1 (da)
CA (1)	CA2141231A1 (da)
DE (1)	DE69521223T2 (da)
DK (1)	DK0668279T3 (da)
ES (1)	ES2157292T3 (da)
GR (1)	GR3036570T3 (da)
PT (1)	PT668279E (da)
SI (1)	SI0668279T1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5187991B2 (ja) *	1997-10-17	2013-04-24	アーク・セラピューティックス・リミテッド	レニン−アンジオテンシン系の阻害剤の使用
PL340412A1 (en)	1997-10-20	2001-01-29	Hoffmann La Roche	Bicyclic kinase inhibitors
DE69914563T2 (de) *	1998-10-30	2004-12-16	Eli Lilly And Co., Indianapolis	Azaindol derivate und ihre Verwendung als antithrombotische Wirkstoffe
JP2002538205A (ja) *	1999-03-10	2002-11-12	メルクエンドカムパニーインコーポレーテッド	性腺刺激ホルモン放出ホルモン拮抗薬としての６−アザインドール化合物
WO2003009852A1 (en) *	2001-07-24	2003-02-06	Merck & Co., Inc.	Tyrosine kinase inhibitors
GB0330043D0 (en) *	2003-12-24	2004-01-28	Pharmacia Italia Spa	Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
DE602005010698D1 (de)	2004-06-09	2008-12-11	Glaxo Group Ltd	Pyrrolopyridinderivate
US20070155738A1 (en)	2005-05-20	2007-07-05	Alantos Pharmaceuticals, Inc.	Heterobicyclic metalloprotease inhibitors
CN112839648A (zh) *	2018-06-07	2021-05-25	达萨玛治疗公司	Sarm1抑制剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1250844A (en) *	1981-06-22	1989-03-07	Neville Ford	Substituted imidazo¬1,5-a\|pyridines, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application
US4588732A (en) *	1982-12-21	1986-05-13	Ciba-Geigy Corporation	Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US4470986A (en) *	1982-12-21	1984-09-11	Ciba-Geigy Corporation	Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
DE3302125A1 (de) *	1983-01-22	1984-07-26	Boehringer Ingelheim KG, 6507 Ingelheim	Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
FR2658511B1 (fr) *	1990-02-16	1992-06-19	Union Pharma Scient Appl	Nouveaux derives de benzimidazole et d'azabenzimidazole, antagonistes des recepteurs au thromboxane; leurs procedes de preparation, compositions pharmaceutiques les contenant.
DE69227561T2 (de) *	1991-08-21	1999-06-02	Eisai Co Ltd	Kondensierte Pyrimidinderivate als Antitumorverbindungen

1994
- 1994-01-31 US US08/189,212 patent/US5468757A/en not_active Expired - Fee Related
1995
- 1995-01-27 CA CA002141231A patent/CA2141231A1/en not_active Abandoned
- 1995-01-30 AT AT95300551T patent/ATE202103T1/de not_active IP Right Cessation
- 1995-01-30 PT PT95300551T patent/PT668279E/pt unknown
- 1995-01-30 SI SI9530517T patent/SI0668279T1/xx unknown
- 1995-01-30 EP EP95300551A patent/EP0668279B1/en not_active Expired - Lifetime
- 1995-01-30 DE DE69521223T patent/DE69521223T2/de not_active Expired - Fee Related
- 1995-01-30 ES ES95300551T patent/ES2157292T3/es not_active Expired - Lifetime
- 1995-01-30 DK DK95300551T patent/DK0668279T3/da active
- 1995-01-31 JP JP7013686A patent/JPH0853448A/ja not_active Withdrawn
2001
- 2001-09-07 GR GR20010401424T patent/GR3036570T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
US5468757A (en)	1995-11-21
JPH0853448A (ja)	1996-02-27
EP0668279A2 (en)	1995-08-23
GR3036570T3 (en)	2001-12-31
SI0668279T1 (en)	2001-12-31
EP0668279B1 (en)	2001-06-13
ES2157292T3 (es)	2001-08-16
EP0668279A3 (en)	1995-08-30
CA2141231A1 (en)	1995-08-01
PT668279E (pt)	2001-09-28
DE69521223T2 (de)	2001-11-08
ATE202103T1 (de)	2001-06-15
DE69521223D1 (de)	2001-07-19

Publication	Publication Date	Title
FI965020A (fi)	1996-12-16	Uusia yhdisteitä, menetelmiä niiden valmistamiseksi ja kasvaintenvastaisia aineita
PT90623A (pt)	1989-11-30	Processo para a preparacao de n-heterociclil-4-guanilalquil-benzamidas uteis como inibidores de protease
KR970704864A (ko)	1997-09-06	세정제 조성물
DE69728544D1 (de)	2004-05-13	Totalsynthese von acylfulvenen mit antitumorwirkung
DK0668279T3 (da)	2001-08-27	6-azaindol thromboxansytaseinhibitor
ATE232528T1 (de)	2003-02-15	Pyrimidinylpyrazolderivate
ES2188481T3 (es)	2003-07-01	Derivados de polinalbufina.
DE69808099T2 (de)	2003-05-15	Substituierte 6-alkylphenanthridine
FI940731A (fi)	1994-04-15	Amiditetratsolit ACAT-inhibiitoreina
ES2169220T3 (es)	2002-07-01	Derivados de vitamina d3 con sustituyentes en la posicion 2.
ES2087247T3 (es)	1996-07-16	Inhibidor de aldosa reductasa.
NO900732D0 (no)	1990-02-15	Arylalkylaminforbindelser.
ATE245147T1 (de)	2003-08-15	Substituierte aminochinazolinon (thion) derivate
ES2093838T3 (es)	1997-01-01	Inhibidor de fosfolipasa a2.
MX9603348A (es)	1997-12-31	Derivados de disulfuro de amida indano-2-mercaptoacetilica novedosos utiles como inhibidores de encefalinasa.
NO20004477L (no)	2001-03-12	Anvendelse av organiske karbonater for vasking av metalloverflater
DE60221250D1 (de)	2007-08-30	Bis(5-aryl-2-pyridyl)derivate
ES2121036T3 (es)	1998-11-16	Derivados de alquilenodiamina.
BR0210201A (pt)	2004-06-08	Composição
DE60230924D1 (de)	2009-03-05	2-substituierte vitamin-d-derivate
TH13791EX (th)	1994-04-15	อนุพันธ์ต่างๆของกรดบิวไทริค
ES2099621T3 (es)	1997-05-16	Procedimiento para producir un derivado de imidazol.