DK0649434T3 - Radioaktivt mærkede somatostatin-afledte peptider til billeddannende og terapeutiske anvendelser - Google Patents
Radioaktivt mærkede somatostatin-afledte peptider til billeddannende og terapeutiske anvendelserInfo
- Publication number
- DK0649434T3 DK0649434T3 DK93918129T DK93918129T DK0649434T3 DK 0649434 T3 DK0649434 T3 DK 0649434T3 DK 93918129 T DK93918129 T DK 93918129T DK 93918129 T DK93918129 T DK 93918129T DK 0649434 T3 DK0649434 T3 DK 0649434T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptides
- imaging
- therapeutic applications
- derived peptides
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/902,935 US5716596A (en) | 1992-06-23 | 1992-06-23 | Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses |
PCT/US1993/006029 WO1994000489A2 (en) | 1992-06-23 | 1993-06-23 | Radioactively-labeled somatostantin-derived peptides for imaging and therapeutic uses |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0649434T3 true DK0649434T3 (da) | 2001-11-12 |
Family
ID=25416650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93918129T DK0649434T3 (da) | 1992-06-23 | 1993-06-23 | Radioaktivt mærkede somatostatin-afledte peptider til billeddannende og terapeutiske anvendelser |
Country Status (10)
Country | Link |
---|---|
US (5) | US5716596A (da) |
EP (2) | EP0649434B1 (da) |
JP (1) | JPH08503924A (da) |
AT (1) | ATE203754T1 (da) |
AU (1) | AU690071B2 (da) |
CA (1) | CA2138647C (da) |
DE (1) | DE69330521T2 (da) |
DK (1) | DK0649434T3 (da) |
ES (1) | ES2164667T3 (da) |
WO (1) | WO1994000489A2 (da) |
Families Citing this family (58)
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US5443816A (en) * | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
US5645815A (en) | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
US5965107A (en) * | 1992-03-13 | 1999-10-12 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
US5849261A (en) * | 1991-02-08 | 1998-12-15 | Diatide, Inc. | Radiolabeled vasoactive intestinal peptides for diagnosis and therapy |
US5736122A (en) * | 1991-02-08 | 1998-04-07 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US5997844A (en) * | 1991-02-08 | 1999-12-07 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
US5443815A (en) * | 1991-11-27 | 1995-08-22 | Diatech, Inc. | Technetium-99m labeled peptides for imaging |
US7238340B1 (en) * | 1991-11-27 | 2007-07-03 | Cis Bio International | Monoamine, diamide, thiol-containing metal chelating agents |
DK0570493T3 (da) * | 1991-02-08 | 2000-06-26 | Diatide Inc | Technetium-99m-mærkede polypeptider til billeddannelse. |
US6183722B1 (en) * | 1991-11-27 | 2001-02-06 | Diatide, Inc. | Somatostatin analogs |
US5783170A (en) * | 1991-11-27 | 1998-07-21 | Diatide, Inc. | Peptide-metal chelate conjugates |
US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US6017512A (en) * | 1992-06-23 | 2000-01-25 | Diatide, Inc. | Radiolabeled peptides |
US5620675A (en) | 1992-06-23 | 1997-04-15 | Diatech, Inc. | Radioactive peptides |
DE69434832D1 (de) * | 1993-06-23 | 2006-10-05 | Diatide Inc | Radioaktiv-markierte Peptidderivate des Somatostatins zur bildformenden und therapeutischen Verwendung |
US5932189A (en) * | 1994-07-29 | 1999-08-03 | Diatech, Inc. | Cyclic peptide somatostatin analogs |
ATE196609T1 (de) * | 1993-07-28 | 2000-10-15 | Diatide Inc | Radiomarkierte glukane |
DK96493D0 (da) * | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
DE69529988T2 (de) * | 1994-05-02 | 2003-12-11 | Diatide, Inc. | Technetium-99m markierte bildformungsmittel |
US6051206A (en) * | 1994-06-03 | 2000-04-18 | Diatide, Inc | Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses |
US5556939A (en) * | 1994-10-13 | 1996-09-17 | Merck Frosst Canada, Inc. | TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications |
US5753206A (en) * | 1995-06-07 | 1998-05-19 | Immunomedics, Inc. | Radiometal-binding analogues of luteinizing hormone releasing hormone |
US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
MY147327A (en) | 1995-06-29 | 2012-11-30 | Novartis Ag | Somatostatin peptides |
DE19536783A1 (de) * | 1995-09-21 | 1997-03-27 | Diagnostikforschung Inst | Bifunktionelle Nicotinamid-Chelatbildner vom Typ N¶2¶S¶2¶ für radioaktive Isotope |
US6331285B1 (en) | 1996-06-05 | 2001-12-18 | Palatin Technologies, Inc. | Structurally determined cyclic metallo-constructs and applications |
CA2264007A1 (en) * | 1996-08-23 | 1998-02-26 | Patel, Cell & Receptor Technologies Inc. | Agonist-dependent internalization of human somatostatin receptors types 1-5 |
WO1999055385A2 (de) * | 1998-04-28 | 1999-11-04 | Wolfgang Bergter | Radioimmunpharmaka zur therapie der hepatitis c |
US6652836B2 (en) | 1998-10-15 | 2003-11-25 | Fluoroprobe, Inc. | Method for viewing tumor tissue located within a body cavity |
US6870914B1 (en) * | 1999-01-29 | 2005-03-22 | Sbc Properties, L.P. | Distributed text-to-speech synthesis between a telephone network and a telephone subscriber unit |
MY133346A (en) * | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
US6254852B1 (en) | 1999-07-16 | 2001-07-03 | Dupont Pharmaceuticals Company | Porous inorganic targeted ultrasound contrast agents |
US6358491B1 (en) * | 1999-08-27 | 2002-03-19 | Berlex Laboratories, Inc. | Somatostatin analogs |
US6685914B1 (en) | 1999-09-13 | 2004-02-03 | Bristol-Myers Squibb Pharma Company | Macrocyclic chelants for metallopharmaceuticals |
US7067111B1 (en) * | 1999-10-25 | 2006-06-27 | Board Of Regents, University Of Texas System | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging |
GB0018891D0 (en) | 2000-08-01 | 2000-09-20 | Novartis Ag | Organic compounds |
CN1292798C (zh) | 2000-06-02 | 2007-01-03 | 德克萨斯州立大学董事会 | 乙二半胱氨酸(ec)-药物缀合物 |
US7385025B2 (en) | 2000-12-19 | 2008-06-10 | Palatin Technologies, Inc. | Metallopeptide compounds |
FR2845389B1 (fr) * | 2002-10-04 | 2007-01-12 | Solvay | Procede pour la synthese de peptides comprenant au moins une molecule de glycine |
WO2004081031A2 (en) * | 2003-03-10 | 2004-09-23 | Biogen Idec Inc. | Thiol-mediated drug attachment to targeting peptides |
AR044852A1 (es) | 2003-06-24 | 2005-10-05 | Novartis Ag | Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina |
WO2005018682A2 (en) | 2003-08-20 | 2005-03-03 | The Regents Of The University Of California | Somatostatin analogs with inhibitory activity to growth hormone release |
US9050378B2 (en) * | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
US8986650B2 (en) | 2005-10-07 | 2015-03-24 | Guerbet | Complex folate-NOTA-Ga68 |
CA2625196C (fr) | 2005-10-07 | 2016-04-05 | Guerbet | Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium |
US8758723B2 (en) | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
US10925977B2 (en) * | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
US20100215581A1 (en) * | 2006-10-25 | 2010-08-26 | Koninklijke Philips Electronics N.V. | Contrast agents for detecting prostate cancer |
EP2197340A4 (en) * | 2007-09-19 | 2015-10-21 | Oncofluor Inc | METHOD FOR THE PRESENTATION AND TREATMENT OF ORGANS AND WOVEN FABRICS |
FR2942227B1 (fr) | 2009-02-13 | 2011-04-15 | Guerbet Sa | Utilisation de tampons pour la complexation de radionucleides |
FR2968999B1 (fr) | 2010-12-20 | 2013-01-04 | Guerbet Sa | Nanoemulsion de chelate pour irm |
FR2980364B1 (fr) | 2011-09-26 | 2018-08-31 | Guerbet | Nanoemulsions et leur utilisation comme agents de contraste |
US20140147381A1 (en) * | 2012-11-29 | 2014-05-29 | Gregory David Espenan | 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment |
FR3001154B1 (fr) | 2013-01-23 | 2015-06-26 | Guerbet Sa | Magneto-emulsion vectorisee |
WO2014149069A1 (en) | 2013-03-15 | 2014-09-25 | Purdue Research Foundation | Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors |
CA2988591A1 (en) * | 2015-06-30 | 2017-01-05 | Tarveda Therapeutics, Inc. | Targeted conjugates and particles and formulations thereof |
WO2020007822A1 (en) | 2018-07-02 | 2020-01-09 | Conservatoire National Des Arts Et Metiers (Cnam) | Bismuth metallic (0) nanoparticles, process of manufacturing and uses thereof |
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CH379524A (de) | 1959-05-05 | 1964-07-15 | Inventa Ag | Verfahren zur Herstellung von Methionin |
NL7607987A (nl) * | 1975-08-08 | 1977-02-10 | Merck & Co Inc | Werkwijze voor het bereiden van peptiden. |
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JPH02504387A (ja) * | 1987-04-02 | 1990-12-13 | セントカー・カーデイオバスキユラー・イメージング・パートナーズ・エルピー | 金属イオンで抗体を標識付けする方法 |
US5073541A (en) * | 1987-11-18 | 1991-12-17 | Administrators Of The Tulane Educational Fund | Treatment of small cell lung cancer with somatostatin analogs |
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DK0450480T3 (da) * | 1990-04-06 | 1995-08-14 | Univ Tulane | Somatostatinaloger |
US5382654A (en) * | 1992-02-05 | 1995-01-17 | Mallinckrodt Medical, Inc. | Radiolabelled peptide compounds |
US5443815A (en) * | 1991-11-27 | 1995-08-22 | Diatech, Inc. | Technetium-99m labeled peptides for imaging |
DE69229436T2 (de) * | 1991-02-08 | 1999-11-25 | Biomeasure, Inc. | Verwendung von somatostatinanalogen zur behandlung von melanomen |
US5409894A (en) * | 1991-03-14 | 1995-04-25 | Sandoz Ltd. | Method of preventing balloon catheterization blood vessel damage |
CA2102633A1 (en) * | 1991-06-03 | 1992-12-04 | Peter H. Cox | Radiolabelled somatostatin derivatives, their preparation and use |
DE69225597T2 (de) * | 1991-08-09 | 1998-11-26 | Kolbeck, Winfried, 81247 Muenchen | Peptide mit einer lanthionin-brücke |
US5225180A (en) * | 1991-09-10 | 1993-07-06 | Diatech, Inc. | Technetium-99m labeled somatostatin-derived peptides for imaging |
US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
US5620675A (en) * | 1992-06-23 | 1997-04-15 | Diatech, Inc. | Radioactive peptides |
DE69434832D1 (de) * | 1993-06-23 | 2006-10-05 | Diatide Inc | Radioaktiv-markierte Peptidderivate des Somatostatins zur bildformenden und therapeutischen Verwendung |
US5443806A (en) * | 1994-03-22 | 1995-08-22 | A. Ahlstrom Corporation | Treating exhaust gas from a pressurized fluidized bed reaction system |
-
1992
- 1992-06-23 US US07/902,935 patent/US5716596A/en not_active Expired - Fee Related
-
1993
- 1993-06-23 DE DE69330521T patent/DE69330521T2/de not_active Expired - Fee Related
- 1993-06-23 CA CA002138647A patent/CA2138647C/en not_active Expired - Fee Related
- 1993-06-23 DK DK93918129T patent/DK0649434T3/da active
- 1993-06-23 EP EP93918129A patent/EP0649434B1/en not_active Expired - Lifetime
- 1993-06-23 WO PCT/US1993/006029 patent/WO1994000489A2/en active IP Right Grant
- 1993-06-23 EP EP00122243A patent/EP1094074A3/en not_active Withdrawn
- 1993-06-23 JP JP6502568A patent/JPH08503924A/ja not_active Expired - Lifetime
- 1993-06-23 AU AU47688/93A patent/AU690071B2/en not_active Ceased
- 1993-06-23 ES ES93918129T patent/ES2164667T3/es not_active Expired - Lifetime
- 1993-06-23 AT AT93918129T patent/ATE203754T1/de not_active IP Right Cessation
-
1995
- 1995-06-06 US US08/470,932 patent/US5833942A/en not_active Expired - Fee Related
- 1995-06-06 US US08/465,764 patent/US5814298A/en not_active Expired - Fee Related
- 1995-06-06 US US08/467,025 patent/US5843401A/en not_active Expired - Fee Related
- 1995-06-06 US US08/466,100 patent/US5820845A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE203754T1 (de) | 2001-08-15 |
WO1994000489A3 (en) | 1994-03-31 |
EP1094074A2 (en) | 2001-04-25 |
DE69330521T2 (de) | 2002-05-16 |
US5814298A (en) | 1998-09-29 |
JPH08503924A (ja) | 1996-04-30 |
EP1094074A3 (en) | 2002-01-09 |
EP0649434A1 (en) | 1995-04-26 |
US5820845A (en) | 1998-10-13 |
US5833942A (en) | 1998-11-10 |
AU4768893A (en) | 1994-01-24 |
ES2164667T3 (es) | 2002-03-01 |
EP0649434B1 (en) | 2001-08-01 |
CA2138647C (en) | 2002-11-12 |
WO1994000489A2 (en) | 1994-01-06 |
CA2138647A1 (en) | 1994-01-06 |
AU690071B2 (en) | 1998-04-23 |
US5843401A (en) | 1998-12-01 |
US5716596A (en) | 1998-02-10 |
DE69330521D1 (de) | 2001-09-06 |
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