DK0594772T3 - - Google Patents

Info

Publication number
DK0594772T3
DK0594772T3 DK92916161.0T DK92916161T DK0594772T3 DK 0594772 T3 DK0594772 T3 DK 0594772T3 DK 92916161 T DK92916161 T DK 92916161T DK 0594772 T3 DK0594772 T3 DK 0594772T3
Authority
DK
Denmark
Prior art keywords
carrier molecule
attached
group
reagents
divinyl sulfone
Prior art date
Application number
DK92916161.0T
Other languages
Danish (da)
English (en)
Inventor
Allan Otto Fog Lihme
Thomas Boenisch
Original Assignee
Immunodex K S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065568&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0594772(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK911309A external-priority patent/DK130991D0/da
Application filed by Immunodex K S filed Critical Immunodex K S
Application granted granted Critical
Publication of DK0594772T3 publication Critical patent/DK0594772T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
DK92916161.0T 1991-07-04 1992-06-29 DK0594772T3 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK911309A DK130991D0 (da) 1991-07-04 1991-07-04 Polymere konjugater
US07/789,757 US5543332A (en) 1991-07-04 1991-11-08 Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone

Publications (1)

Publication Number Publication Date
DK0594772T3 true DK0594772T3 (pt) 1997-02-24

Family

ID=26065568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92916161.0T DK0594772T3 (pt) 1991-07-04 1992-06-29

Country Status (12)

Country Link
EP (1) EP0594772B1 (pt)
JP (1) JP3340434B2 (pt)
AT (1) ATE142021T1 (pt)
AU (1) AU667051B2 (pt)
CA (1) CA2112992C (pt)
DE (1) DE69213240T2 (pt)
DK (1) DK0594772T3 (pt)
ES (1) ES2094920T3 (pt)
FI (1) FI115413B (pt)
GR (1) GR3021806T3 (pt)
NO (1) NO315443B1 (pt)
WO (1) WO1993001498A1 (pt)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552170B1 (en) * 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US5773227A (en) * 1993-06-23 1998-06-30 Molecular Probes, Inc. Bifunctional chelating polysaccharides
US5446090A (en) * 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
JPH10500310A (ja) * 1994-05-19 1998-01-13 ダコ アクティーゼルスカブ 淋菌及びトラコーマ クラミジアの検出のためのpna プローブ
US5888733A (en) * 1995-11-16 1999-03-30 Dako A/S In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
US6309646B1 (en) * 1996-05-09 2001-10-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
GB9624165D0 (en) 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
DE69724451T2 (de) 1996-12-06 2004-03-18 Amgen Inc., Thousand Oaks Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen
US6709873B1 (en) * 1997-04-09 2004-03-23 Isodiagnostika Inc. Method for production of antibodies to specific sites of rapamycin
US5994089A (en) * 1997-05-16 1999-11-30 Coulter International Corp. Simultaneous analyses of white blood cell subsets using multi-color, multi-intensity fluorescent markers in flow cytometry
US6066446A (en) * 1997-12-19 2000-05-23 Nen Life Science Products, Inc. Assay member and method for its manufacture
WO1999040438A1 (en) * 1998-02-03 1999-08-12 Synbiotics Corporation Device and method to detect immunoprotective antibody titers
EP1101115B1 (en) * 1998-07-30 2004-06-09 Oakville Trading Hong Kong Limited Method for preparing water-soluble cross-linked conjugates
US6686454B1 (en) * 1998-10-09 2004-02-03 Isotechnika, Inc. Antibodies to specific regions of cyclosporine related compounds
JP3595506B2 (ja) * 1998-10-09 2004-12-02 アイソテクニカ インコーポレイテッド シクロスポリンおよびシクロスポリン代謝産物の、特定領域に対する抗体の生産方法
JP3781934B2 (ja) 1999-12-22 2006-06-07 株式会社ニチレイバイオサイエンス 酵素−タンパク質複合体
DE10039112A1 (de) * 2000-08-07 2002-03-07 Pe Diagnostik Gmbh Verfahren zum Herstellen von Antikörper aus einer verunreinigten Antigenlösung
GB0029617D0 (en) * 2000-12-05 2001-01-17 Norchip As Ligand detection method
AU2002240818C1 (en) 2001-03-14 2008-11-06 Agilent Technologies, Inc. MHC molecule constructs and their uses for diagnosis and therapy
US7034127B2 (en) * 2002-07-02 2006-04-25 Genzyme Corporation Hydrophilic biopolymer-drug conjugates, their preparation and use
EP1405907A3 (en) * 2002-07-22 2004-10-13 Roche Diagnostics GmbH Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof
CA2433479A1 (en) 2002-07-22 2004-01-22 F. Hoffmann-La Roche Ag Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof
WO2005062048A1 (de) * 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogenes nachweisverfahren
JP4949038B2 (ja) 2003-12-01 2012-06-06 ダコ デンマーク アクティーゼルスカブ 免疫組織化学的検出のための方法および組成物
CA2547353A1 (en) * 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Conjugates, and use thereof in detection methods
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426823D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
JP5118029B2 (ja) 2005-06-14 2013-01-16 タイゲン バイオテクノロジー カンパニー,リミテッド ピリミジン化合物
US8193206B2 (en) 2005-06-14 2012-06-05 Taigen Biotechnology Co., Ltd. Pyrimidine compounds
WO2007123507A1 (en) 2006-03-20 2007-11-01 Inverness Medical Switzerland Gmbh Water-soluble conjugates for electrochemical detection
EP2361930A3 (en) * 2007-03-26 2011-10-26 Dako Denmark A/S Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
EP2167536A1 (en) 2007-07-03 2010-03-31 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
PT2268635E (pt) 2008-04-21 2015-10-06 Taigen Biotechnology Co Ltd Compostos heterocíclicos
WO2010009735A2 (en) 2008-07-23 2010-01-28 Dako Denmark A/S Combinatorial analysis and repair
DK2334703T3 (en) 2008-09-17 2015-10-05 Innate Pharma Configurations and methods for detection of tlr3
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
WO2010056847A2 (en) 2008-11-13 2010-05-20 Taigen Biotechnology Co., Ltd. Lyophilization formulation
EP2270506A3 (en) * 2009-07-02 2011-03-09 Amic AB Amplified labeled conjugate for use in immunoassays
US9315860B2 (en) 2009-10-26 2016-04-19 Genovoxx Gmbh Conjugates of nucleotides and method for the application thereof
US9567631B2 (en) 2012-12-14 2017-02-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
KR102090851B1 (ko) 2012-08-14 2020-03-19 10엑스 제노믹스, 인크. 마이크로캡슐 조성물 및 방법
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN108753766A (zh) 2013-02-08 2018-11-06 10X基因组学有限公司 多核苷酸条形码生成
EP3015474A4 (en) 2013-06-28 2017-01-11 Kyushu University, National University Corporation PROTEIN-POLYMER COMPLEX, TGase SUBSTRATE-CONTAINING POLYMER, TGase SUBSTRATE-CONTAINING MONOMER, METHOD FOR PRODUCING PROTEIN-POLYMER COMPLEX, AND METHOD FOR IMPROVING PROTEIN FUNCTION ON INTERFACE OR IN VICINITIY OF INTERFACE OF SOLID-LIQUID
CN106413896B (zh) 2014-04-10 2019-07-05 10X基因组学有限公司 用于封装和分割试剂的流体装置、***和方法及其应用
EP4270006A3 (en) 2014-06-13 2024-01-10 Immudex ApS General detection and isolation of specific cells by binding of labeled molecules
EP3889325A1 (en) 2014-06-26 2021-10-06 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
AU2016207023B2 (en) 2015-01-12 2019-12-05 10X Genomics, Inc. Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
WO2016137973A1 (en) 2015-02-24 2016-09-01 10X Genomics Inc Partition processing methods and systems
JP6954899B2 (ja) 2015-12-04 2021-10-27 10エックス ゲノミクス,インコーポレイテッド 核酸の解析のための方法及び組成物
EP3430402A1 (en) 2016-03-15 2019-01-23 Mipsalus Aps Detection method and means therefor
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2018140966A1 (en) 2017-01-30 2018-08-02 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
US20180340169A1 (en) 2017-05-26 2018-11-29 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN109526228B (zh) 2017-05-26 2022-11-25 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
WO2019157529A1 (en) 2018-02-12 2019-08-15 10X Genomics, Inc. Methods characterizing multiple analytes from individual cells or cell populations
EP3775271A1 (en) 2018-04-06 2021-02-17 10X Genomics, Inc. Systems and methods for quality control in single cell processing
US10871485B2 (en) 2018-04-13 2020-12-22 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same
WO2021152178A1 (en) 2020-01-31 2021-08-05 Cell.Copedia GmbH Methods of isolating a biological entity
CA3186062A1 (en) 2020-08-10 2022-02-17 Marion BENEZECH Cell surface mica and micb detection using antibodies
CN111965341B (zh) * 2020-08-10 2023-04-11 武汉菲恩生物科技有限公司 一种基于葡聚糖的HRP-羊抗鼠IgG标记抗体及其制备方法
CN117242093A (zh) 2021-04-05 2023-12-15 先天制药公司 免疫组织化学方法和kir3dl2特异性试剂
CN115537410A (zh) * 2022-09-27 2022-12-30 凯莱英医药化学(阜新)技术有限公司 酶固定化载体及其制备方法、固定化酶及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712344C2 (de) * 1977-03-21 1982-09-23 Hans Dr. 4803 Steinhagen Bünemann Löslicher Komplexbildner für die affinitätsspezifische Trennung von Nukleinsäuren
SE7812237L (sv) * 1978-11-28 1980-05-29 Pharmacia Diagnostics Ab Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
FR2453847B1 (fr) * 1979-04-13 1985-08-16 Anvar Procede pour l'obtention d'ampholytes porteurs utilisables dans les diverses techniques d'electrofocalisation
US4752339A (en) * 1983-10-31 1988-06-21 Hi-Tek Polymers, Inc. Thixotropic aqueous solutions containing a divinylsulfone-crosslinked polygalactomannan gum
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
CA1304682C (en) * 1986-11-19 1992-07-07 Nobuo Monji Membrane affinity concentration immunoassay
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices
CA1341592C (en) * 1989-07-07 2009-04-14 Abbott Laboratories Ion capture reagents and methods for performing binding assays

Also Published As

Publication number Publication date
CA2112992C (en) 2002-06-11
ATE142021T1 (de) 1996-09-15
DE69213240T2 (de) 1997-04-24
EP0594772A1 (en) 1994-05-04
WO1993001498A1 (en) 1993-01-21
DE69213240D1 (de) 1996-10-02
NO940030D0 (no) 1994-01-04
NO940030L (no) 1994-03-03
NO315443B1 (no) 2003-09-01
FI115413B (fi) 2005-04-29
AU2348992A (en) 1993-02-11
JPH06509167A (ja) 1994-10-13
AU667051B2 (en) 1996-03-07
GR3021806T3 (en) 1997-02-28
CA2112992A1 (en) 1993-01-21
FI940023A (fi) 1994-02-25
FI940023A0 (fi) 1994-01-04
EP0594772B1 (en) 1996-08-28
ES2094920T3 (es) 1997-02-01
JP3340434B2 (ja) 2002-11-05

Similar Documents

Publication Publication Date Title
DK0594772T3 (pt)
US5109124A (en) Nucleic acid probe linked to a label having a terminal cysteine
EP0154884A2 (en) Nucleic acid-protein conjugate
US5650334A (en) Fluorescent labelling compositions and methods for their use
US5728588A (en) Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
Nakamura et al. Detection and removal of Escherichia coli using fluorescein isothiocyanate conjugated monoclonal antibody immobilized on bacterial magnetic particles
CN1323294C (zh) 制备水溶***联轭合物的方法
CA1341592C (en) Ion capture reagents and methods for performing binding assays
JP3124018B2 (ja) 結合アッセイ用固相の調製方法
EP0128332A1 (en) Assay method utilizing polynucleotide sequences
EP0040365B1 (en) An assaying method involving biospecific affinity reactions
US4670380A (en) Assays utilizing labeled nucleic acid probes
EP0397113A3 (de) Verfahren zum Nachweis spezifisch bindefähiger Substanzen in Körperflüssigkeiten
EP2021793A1 (en) Polymer backbone element tags
Ngo Facile activation of Sepharose hydroxyl groups by 2-fluoro-1 methylpyridinium toluene-4-sulfonate: preparation of affinity and covalent chromatographic matrices
KR920015133A (ko) 숙신이미드함유 중합체로 생물학적 활성 시약을 제조하는 방법, 분석 요소 및 이것의 사용방법
JPH05504481A (ja) 改良された抗体―酵素直接接合体及びその製造方法
EP0256117A1 (en) Latex agglutination using avidin/biotin system
GB2238384A (en) Oligomer/polymer label
WO1995025282A1 (en) Ion-capture reagents and methods for performing binding assays
Montesano et al. Wheat germ cytoplasmic ribosomes. Localization of 7-methylguanosine and 6-methyladenosine by electron microscopy of immune complexes.
CN116953222A (zh) 一种纳米聚合酶标记抗体及其制备方法和应用
WO1999004042A1 (en) Synthetic oligonucleotide-peptide conjugates and methods of use
WO1988008981A1 (en) Immobilization of receptor molecules to hydrophobic water soluble polymer in separation methods on assays
Wilchek et al. [36] Affinity cytochemistry