DK0563249T3 - Målretning af terapeutiske midler under anvendelse af polysaccharider - Google Patents

Målretning af terapeutiske midler under anvendelse af polysaccharider

Info

Publication number
DK0563249T3
DK0563249T3 DK92902979.1T DK92902979T DK0563249T3 DK 0563249 T3 DK0563249 T3 DK 0563249T3 DK 92902979 T DK92902979 T DK 92902979T DK 0563249 T3 DK0563249 T3 DK 0563249T3
Authority
DK
Denmark
Prior art keywords
targeting
therapeutic agent
polysaccharides
complex
therapeutic agents
Prior art date
Application number
DK92902979.1T
Other languages
English (en)
Inventor
Jerome M Lewis
Lee Josephson
Ernest V Groman
Chu Jung
Original Assignee
Advanced Magnetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Magnetics Inc filed Critical Advanced Magnetics Inc
Application granted granted Critical
Publication of DK0563249T3 publication Critical patent/DK0563249T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Nanotechnology (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92902979.1T 1990-12-19 1991-12-13 Målretning af terapeutiske midler under anvendelse af polysaccharider DK0563249T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63001790A 1990-12-19 1990-12-19
PCT/US1991/009368 WO1992011037A2 (en) 1990-12-19 1991-12-13 Targeting of therapeutic agents using polysaccharides

Publications (1)

Publication Number Publication Date
DK0563249T3 true DK0563249T3 (da) 1997-11-03

Family

ID=24525421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92902979.1T DK0563249T3 (da) 1990-12-19 1991-12-13 Målretning af terapeutiske midler under anvendelse af polysaccharider

Country Status (9)

Country Link
EP (1) EP0563249B1 (da)
JP (1) JP3357362B2 (da)
AT (1) ATE151991T1 (da)
CA (1) CA2097589C (da)
DE (2) DE563249T1 (da)
DK (1) DK0563249T3 (da)
ES (1) ES2059299T3 (da)
GR (2) GR940300001T1 (da)
WO (1) WO1992011037A2 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5490991A (en) * 1986-07-03 1996-02-13 Advanced Magnetics, Inc. Directed delivery of radioprotectants using a receptor specific carrier
US5554386A (en) * 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
GB9119762D0 (en) * 1991-09-16 1991-10-30 Filler Aaron G Particulate agents for nmt
US7097839B1 (en) 1993-10-26 2006-08-29 Thomas Jefferson University ST receptor binding compounds and methods of using the same
PT101422B (pt) * 1993-12-06 1997-06-30 Ineti Inst Biotec Q F E Tecnol Formulacoes lipossomicas contendo vidarabina e/ou derivados, com indice terapeutico elevado e processo para a sua preparacao
GB9600427D0 (en) * 1996-01-10 1996-03-13 Nycomed Imaging As Contrast media
PL327679A1 (en) 1996-01-10 1998-12-21 Nycomed Imaging As Contast medium
FR2755976B1 (fr) * 1996-11-15 1999-01-15 Idm Immuno Designed Molecules Nouveaux complexes d'acides nucleiques et de polymere substitue par des residus entrainant la destabilisation des membranes cellulaires
US6093382A (en) 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
NZ511072A (en) 1998-10-05 2004-03-26 Penn State Res Found Method for enhancing receptor-mediated cellular internalization using a composition of an active agent and a viscous material and an enhancer
AU5085800A (en) * 1999-05-21 2000-12-12 Nycomed Imaging As Method of magnetic resonance imaging
GB9921579D0 (da) * 1999-09-13 1999-11-17 Nycomed Imaging As
US7082326B2 (en) 2000-03-31 2006-07-25 Amersham Health As Method of magnetic resonance imaging
CN1095472C (zh) * 2000-04-17 2002-12-04 上海复康医药科技发展有限公司 叶酸-多聚糖复合物,其制备方法和以该复合物为活性成分的药物组合物
IT1319665B1 (it) * 2000-11-17 2003-10-23 Pharma Biotech Ltd Addotti di corticosteroidi con polimeri polisaccaridici naturali.
DE10209822A1 (de) * 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
KR101234476B1 (ko) 2004-03-05 2013-02-18 덴끼 가가꾸 고교 가부시키가이샤 히알루론산/메토트렉세이트 화합물
TW200536861A (en) * 2004-04-02 2005-11-16 Denki Kagaku Kogyo Kk Hyaluronic acid/methotrexate compound
JP2013053103A (ja) * 2011-09-05 2013-03-21 Ltt Bio-Pharma Co Ltd 薬物を封入した肝臓集積性ナノ粒子

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857505A (en) * 1987-03-09 1989-08-15 American Cyanamid Company Sustained release compositions for parenteral administration and their use
DE68926708T2 (de) * 1988-08-04 1996-10-31 Advanced Magnetics Inc Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri

Also Published As

Publication number Publication date
GR3023358T3 (en) 1997-08-29
CA2097589C (en) 1998-05-05
ES2059299T1 (es) 1994-11-16
DE69125848T2 (de) 1997-07-31
ATE151991T1 (de) 1997-05-15
ES2059299T3 (es) 1997-10-01
DE563249T1 (de) 1994-03-03
JPH06503347A (ja) 1994-04-14
EP0563249B1 (en) 1997-04-23
JP3357362B2 (ja) 2002-12-16
GR940300001T1 (en) 1994-02-28
EP0563249A1 (en) 1993-10-06
CA2097589A1 (en) 1992-06-20
DE69125848D1 (de) 1997-05-28
WO1992011037A2 (en) 1992-07-09
WO1992011037A3 (en) 1992-08-06

Similar Documents

Publication Publication Date Title
DK0563249T3 (da) Målretning af terapeutiske midler under anvendelse af polysaccharider
IT7822730A0 (it) Spruzzatore impiegabile sia nello stato eretto che nello stato invertito.
DE3766157D1 (de) Kupplungsmittel zum radiomarkieren von proteinen.
NO900869L (no) Makrocykliske bifunksjonelle chelatiseringsmidler, komplekser derav og deres antistoffkonjugater.
DK507183D0 (da) Bifunktionelt chelateringsmiddel
WO2001005433A3 (en) Delivery and retention of activity agents to lymph nodes
NO177862C (no) Flytende sammensetning innbefattende vann, overflateaktivt middel og opplöst overflateaktivt middel-desolubiliserende elektrolytt
CO4700403A1 (es) Reduccion de efectos colaterales no deseados durante el uso de articulos absorbentes por medio del control del ph
FR2490225B1 (fr) Le maleate de 2-amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine, sa preparation et ses utilisations therapeutiques
SE9700733D0 (sv) Absorberande alster
DK1313508T3 (da) Kombination indeholdende et antifolat og methylkmalonsyresænkende middel
BR0013221A (pt) Chá preto de folha
JO1866B1 (en) Anti-virus agents
NO992604L (no) Oppbygningsundertrykkende midler, blandinger inneholdende slike midler og anvendelse derav i polymeriseringsprosessen
NO913450L (no) Fremgangsmaate til samtidig hydrogenering av et alken og dehydrogenering av et alkan i et apparat for kombinert hydrogenering/dehydrogenering.
GB1556176A (en) Cationic fabric softening and anti static agents with an solubility in water
BE875105A (fr) 3-0-(beta-d-glucuronopyrannosyl)-soyasapogenol b, sa preparation et ses utilisations therapeutiques
YU180791A (sh) Injekcioni proizvod za sitni pesak i druge porozne materijale
EP0213881A3 (en) The use of amphipathic molecules for radioimaging and therapy with conjugates of monoclonal or polyclonal antibodies
FR2682794B1 (fr) Borne mobile delivrant de facon simultanee des messages visuels et olfactifs vers le public.
BE877982A (fr) Nouvelles 2-(5-pyrazolylamido)-2-imidazolines, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant
ES482692A1 (es) Hoja de muelle en especial para muelles de ballesta en vehi-culos utilitarios.
CRESCINI et al. LA Phillyrea iatifolia L. NEL TERRITORIO BRESCIANO
IT1261778B (it) Piastra di ancoraggio cuneiforme.
JPS5439647A (en) Optical branching device of optical fibers