DK0563112T3 - Probucol-holdigt lægemiddel med forøget biotilgængelighed - Google Patents

Probucol-holdigt lægemiddel med forøget biotilgængelighed

Info

Publication number
DK0563112T3
DK0563112T3 DK92900932.2T DK92900932T DK0563112T3 DK 0563112 T3 DK0563112 T3 DK 0563112T3 DK 92900932 T DK92900932 T DK 92900932T DK 0563112 T3 DK0563112 T3 DK 0563112T3
Authority
DK
Denmark
Prior art keywords
probucol
fatty acids
containing drug
increased bioavailability
drug
Prior art date
Application number
DK92900932.2T
Other languages
Danish (da)
English (en)
Inventor
Kenneth G Bassler
Phadke S Deepak
Melissa P Neddermeyer
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of DK0563112T3 publication Critical patent/DK0563112T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92900932.2T 1990-12-18 1991-11-15 Probucol-holdigt lægemiddel med forøget biotilgængelighed DK0563112T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62954090A 1990-12-18 1990-12-18

Publications (1)

Publication Number Publication Date
DK0563112T3 true DK0563112T3 (da) 1995-04-10

Family

ID=24523438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92900932.2T DK0563112T3 (da) 1990-12-18 1991-11-15 Probucol-holdigt lægemiddel med forøget biotilgængelighed

Country Status (17)

Country Link
EP (1) EP0563112B1 (de)
JP (1) JP3127998B2 (de)
KR (1) KR0177845B1 (de)
AT (1) ATE117200T1 (de)
AU (1) AU647563B2 (de)
CA (1) CA2097827C (de)
DE (1) DE69106892T2 (de)
DK (1) DK0563112T3 (de)
ES (1) ES2069987T3 (de)
FI (1) FI102457B (de)
GR (1) GR3015837T3 (de)
HU (1) HU210565B (de)
IE (1) IE65578B1 (de)
IL (1) IL100390A (de)
NO (1) NO303526B1 (de)
NZ (1) NZ240961A (de)
WO (1) WO1992010996A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031979A1 (en) * 1994-05-19 1995-11-30 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
EP1140036A2 (de) * 1998-12-18 2001-10-10 Abbott Laboratories Neue formulierungen mit lipid regulierenden wirkstoffen
US6838091B2 (en) 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
AU2571400A (en) * 1999-02-23 2000-09-14 Chugai Seiyaku Kabushiki Kaisha Seam soft capsule preparations containing dihydrobenzofuran derivative
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
WO2005037251A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
US20240000722A1 (en) * 2022-07-01 2024-01-04 Acrotech Biopharma Inc. Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof
CN116617179B (zh) * 2023-05-19 2024-03-29 齐鲁制药有限公司 一种普罗布考软胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862332A (en) * 1967-05-11 1975-01-21 Dow Chemical Co Method of lowering serum cholesterol
US4902513A (en) * 1987-07-31 1990-02-20 Jean Carvais Oral sustained release medicament

Also Published As

Publication number Publication date
FI932769A0 (fi) 1993-06-16
AU9067891A (en) 1992-07-22
KR930702965A (ko) 1993-11-29
NO932236D0 (no) 1993-06-17
NO932236L (no) 1993-06-17
CA2097827C (en) 2002-07-23
EP0563112B1 (de) 1995-01-18
IL100390A (en) 1996-12-05
CA2097827A1 (en) 1992-06-19
DE69106892T2 (de) 1995-05-18
ES2069987T3 (es) 1995-05-16
GR3015837T3 (en) 1995-07-31
EP0563112A1 (de) 1993-10-06
JPH06503340A (ja) 1994-04-14
IE65578B1 (en) 1995-11-01
HU210565B (en) 1995-05-29
KR0177845B1 (ko) 1999-03-20
AU647563B2 (en) 1994-03-24
HUT64218A (en) 1993-12-28
IE914401A1 (en) 1992-07-01
ATE117200T1 (de) 1995-02-15
FI932769A (fi) 1993-06-16
NO303526B1 (no) 1998-07-27
JP3127998B2 (ja) 2001-01-29
FI102457B1 (fi) 1998-12-15
DE69106892D1 (de) 1995-03-02
WO1992010996A1 (en) 1992-07-09
HU9301769D0 (en) 1993-09-28
FI102457B (fi) 1998-12-15
NZ240961A (en) 1994-03-25
IL100390A0 (en) 1992-09-06

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