DK0559018T3 - Taxanderivater, deres fremstilling og anvendelse indenfor onkologi - Google Patents

Taxanderivater, deres fremstilling og anvendelse indenfor onkologi

Info

Publication number
DK0559018T3
DK0559018T3 DK93102632.2T DK93102632T DK0559018T3 DK 0559018 T3 DK0559018 T3 DK 0559018T3 DK 93102632 T DK93102632 T DK 93102632T DK 0559018 T3 DK0559018 T3 DK 0559018T3
Authority
DK
Denmark
Prior art keywords
preparation
oncology
application
taxane derivatives
cyclotaxanes
Prior art date
Application number
DK93102632.2T
Other languages
English (en)
Inventor
Ezio Bombardelli
Bruno Gabetta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK0559018T3 publication Critical patent/DK0559018T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/76Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
    • C07C2603/80Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/86Ring systems containing bridged rings containing four rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK93102632.2T 1992-03-06 1993-02-19 Taxanderivater, deres fremstilling og anvendelse indenfor onkologi DK0559018T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920526A IT1254515B (it) 1992-03-06 1992-03-06 Tassani di interesse oncologico, loro metodo di preparazione ed uso

Publications (1)

Publication Number Publication Date
DK0559018T3 true DK0559018T3 (da) 1996-08-19

Family

ID=11362316

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93102632.2T DK0559018T3 (da) 1992-03-06 1993-02-19 Taxanderivater, deres fremstilling og anvendelse indenfor onkologi

Country Status (15)

Country Link
US (1) US5250722A (da)
EP (1) EP0559018B1 (da)
JP (1) JPH0641010A (da)
KR (1) KR100255524B1 (da)
AT (1) ATE137734T1 (da)
CA (1) CA2091002C (da)
DE (2) DE69302508T2 (da)
DK (1) DK0559018T3 (da)
ES (1) ES2049690T3 (da)
FI (1) FI112208B (da)
GR (2) GR930300141T1 (da)
HK (1) HK1007556A1 (da)
IT (1) IT1254515B (da)
NO (1) NO178965C (da)
RU (2) RU2112770C1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5475120A (en) * 1990-11-02 1995-12-12 University Of Florida Method for the isolation and purification of taxol and its natural analogues
JP2646942B2 (ja) * 1991-08-12 1997-08-27 松下電器産業株式会社 ガード体付電子部品の打抜装置および打抜方法
IT1261667B (it) * 1993-05-20 1996-05-29 Tassano ad attivita' antitumorale.
US5628978A (en) * 1994-12-23 1997-05-13 Intevep, S.A. MTW zeolite for cracking feedstock into olefins and isoparaffins
US6177456B1 (en) 1995-10-02 2001-01-23 Xechem International, Inc. Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
US5854278A (en) * 1995-12-13 1998-12-29 Xechem International, Inc. Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US5807888A (en) * 1995-12-13 1998-09-15 Xechem International, Inc. Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5654448A (en) * 1995-10-02 1997-08-05 Xechem International, Inc. Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
US5840748A (en) * 1995-10-02 1998-11-24 Xechem International, Inc. Dihalocephalomannine and methods of use therefor
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
WO1997044026A1 (en) * 1996-05-22 1997-11-27 Neuromedica, Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
WO2002076402A2 (en) 2001-03-23 2002-10-03 Protarga, Inc. Fatty amine drug conjugates
ATE556706T1 (de) * 2001-03-23 2012-05-15 Luitpold Pharm Inc Fettalkohol-arzneimittel-konjugate
US7201507B2 (en) 2003-12-25 2007-04-10 Ichikoh Industries, Ltd. Projector type vehicle light
JP4405279B2 (ja) 2004-02-17 2010-01-27 市光工業株式会社 プロジェクタ型車両用灯具
EP1883627B1 (en) 2005-05-18 2018-04-18 Pharmascience Inc. Bir domain binding compounds
MY159563A (en) 2006-05-16 2017-01-13 Pharmascience Inc Iap bir domain binding compounds
KR20120140658A (ko) 2010-02-12 2012-12-31 파마사이언스 인크. Iap bir 도메인 결합 화합물
CN105541631B (zh) * 2015-10-26 2017-09-05 云南西力生物技术股份有限公司 绣线菊阿替生素A(spiratisanin A)及其制备方法和在药物上的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380916A (en) * 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives

Also Published As

Publication number Publication date
NO178965C (no) 1996-07-10
KR930019597A (ko) 1993-10-18
RU2119485C1 (ru) 1998-09-27
ATE137734T1 (de) 1996-05-15
KR100255524B1 (ko) 2000-05-01
NO930773L (no) 1993-09-07
HK1007556A1 (en) 1999-04-16
CA2091002A1 (en) 1993-09-07
GR930300141T1 (en) 1994-02-28
ITMI920526A1 (it) 1993-09-06
JPH0641010A (ja) 1994-02-15
FI930977A0 (fi) 1993-03-04
DE559018T1 (de) 1994-03-17
EP0559018B1 (en) 1996-05-08
IT1254515B (it) 1995-09-25
DE69302508D1 (de) 1996-06-13
NO178965B (no) 1996-04-01
ES2049690T1 (es) 1994-05-01
DE69302508T2 (de) 1996-09-12
US5250722A (en) 1993-10-05
FI930977A (fi) 1993-09-07
RU2112770C1 (ru) 1998-06-10
GR3019871T3 (en) 1996-08-31
NO930773D0 (no) 1993-03-03
EP0559018A1 (en) 1993-09-08
ITMI920526A0 (it) 1992-03-06
ES2049690T3 (es) 1996-07-16
FI112208B (fi) 2003-11-14
CA2091002C (en) 2004-06-08

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